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| 1 | 含酒精的肝炎的管理: 当前的概念显示文摘 Alcoholic hepatitis is a devastating form of acute liver injury seen in chronic alcohol abusers with significant morbidity and mortality.It is a multisystem disease that is precipitated by ingesting large quantities of alcohol with genetic and environmental factors playing a role.Prognostic criteria have been developed to predict disease severity and these criteria can serve as indicators to initiate medical therapy.Primary therapy remains abstinence and supportive care,as continued alcohol abuse is the most important risk factor for disease progression.The cornerstone of supportive care remains aggressive nutritional support,and although acute alcoholic hepatitis has been extensively studied,few specific medical therapies have been successful.Corticosteroids remain the most effective medical therapy available in improving short term survival in a select group of patients with alcoholic hepatitis;however,the long-term outcome of drug therapies is still not entirely clear and further clinical investigation is necessary.While liver transplantation for acute alcoholic hepatitis have demonstrated promising results,this practice remains controversial and has not been advocated universally,with most transplant centers requiring a prolonged period of abstinence before considering transplantation.Extracorporeal liver support devices,although still experimental,have been developed as a form of liver support to give additional time for liver regeneration.These have the potential for a significant therapeutic option in the future for this unfortunately dreadful disease. | Hetal A Karsan Samir Parekh | 2012 | World Journal of Hepatology2012,4,12: | 6 |
| 2 | Transjugular intrahepatic porto 全身的分流在老: 为门高血压的复杂并发症的减轻显示文摘 AIM:To present a dedicated series of transjugular intrahepatic porto-systemic shunts(TIPS) in the elderly since data is sparse on this population group.METHODS:A retrospective review was performed of patients at least 65 years of age who underwent TIPS at our institutions between 1997 and 2010.Twentyfive patients were referred for TIPS.We deemed that 2 patients were not considered appropriate candidates due to their markedly advanced liver disease.Of the 23 patients suitable for TIPS,the indications for TIPS placement was portal hypertension complicated by refractory ascites alone(n = 9),hepatic hydrothorax alone(n = 2),refractory ascites and hydrothorax(n = 1),gastrointestinal bleeding alone(n = 8),gastrointestinal bleeding and ascites(n = 3).RESULTS:Of these 23 attempted TIPS procedure patients,21 patients had technically successful TIPS procedures.A total of 29 out of 32 TIPS procedures including revisions were successful in 21 patients with a mean age of 72.1 years(range 65-82 years).Three of the procedures were unsuccessful attempts at TIPS and 8 procedures were successful revisions of our existing TIPS.Sixteen of 21 patients who underwent successful TIPS(excluding 5 patients lost to follow-up) were followed for a mean of 14.7 mo.Ascites and/or hydrothorax was controlled following technically successful procedures in 12 of 13 patients.Bleeding was controlled following technically successful procedures in 10 out of 11 patients.CONCLUSION:We have demonstrated that TIPS is an effective procedure to control refractory complications of portal hypertension in elderly patients. | Mubin I Syed Hetal Karsan Hector Ferral Azim Shaikh Uzma Waheed Talal Akhter Alan Gabbard Kamal Morar Robert Tyrrell | 2012 | World Journal of Hepatology2012,4,2: | 4 |
| 3 | Endoscopic screening for esophageal varices in cirrhosis: Is it ever cost effective?显示文摘 | Brennan M.R. Spiegel Laura Targownik Gareth S. Dulai Hetal A. Karsan Ian M. Gralnek | 2003 | Hepatology2003,,2: | 2 |
| 4 | Formulation and evalution of irbesartan liquisolid tablets显示文摘 | Rikisha B Anuradha P Hetal D | 2011 | Int J Pharm Sci Rev Res2011,9,2: | 1 |
| 5 | Intersive insulin treatment prevents the gression of diabetic microvascular complications in Japanese patients with nan- insulin dependent diabetes mellitus:A randomized prospective 6 year study显示文摘 | Ohkubo Y Kishikawa Hetal | 1995 | Diabtes Res Clin Pratt1995,28,: | 1 |
| 6 | Cloning and sequencing of a phospholipase C gene of Clostridium perfringens 显示文摘 | Shimizu T Hayashi Hetal | 1989 | Biochem Biophys Res Commun1989,160,: | 1 |
| 7 | The pittsburgh sleep quality index:A new instrument for psychiatricand research显示文摘 | Bugsse DJ Reynolds CF Mor RT Hetal | 1989 | Psychiatry Research1989,28,: | 1 |
| 8 | The effect of land use on runoff and soil erosion rates under Mediterranean conditions显示文摘 | Kosmas C Danalatos N C Cammeraat L Hetal | 1997 | Catena1997,29,1: | 1 |
| 9 | Color and oxidative rancidity of gamma and electron beam-irradiated boneless pork chops 显示文摘 | Luchsinger S E Kmpf D Hetal | 1996 | Food Sci1996,61,5: | 1 |
| 10 | Insulin-regulated Glut4 translocation: Membrane proteintrafficking with six distinctive steps显示文摘 | BREWER P D HABTEMICHAEL E N ROMENSKAIA hetal | 2014 | J Biol Chem2014,289,17: | 1 |
| 11 | Influence of banana fibre chemical modification on the mechanical and morphological proper- ties of woven banana fabric/unsaturated polyester resin composites 显示文摘 | Hetal Shah B Srinivasulu Subhas C Shit | 2013 | Polymers from Renewable Resources2013,4,2: | 1 |
| 12 | The effects of fluoxetine on several neurophysiological variables in patients with premature ejaculation 显示文摘 | Yilmaz U Tatlisen A Turan Hetal | 1999 | J Urol1999,161,1: | 1 |
| 13 | Complement activation regulates the capacity of proximal tubular epithelial cell to stimulate alloreactive T cell response显示文摘 | Ke LI Hetal Patel | 2004 | J Am Soc Nephrol2004,15,: | 1 |
| 14 | Macrophages from C3- deficient mice have impaired potency to stimulate alloreaetive T cells 显示文摘 | Wuding Zhou Hetal P Ke Li | 2006 | Blood2006,107,6: | 1 |
| 15 | Systematic Review of the Epidemiology of Urinary Incontinence and Detrusor Overactivity among Patients with Neurogenic Overactive Bladder显示文摘 | Ruffion Alain Castro-diaz David Patel Hetal Khalaf Kristin Onyenwenyi Ahunna Globe Denise Lereun Corinne Teneishvili Mamuka Edwards Meredith | 2013 | Neuroepidemiology . 2013 (3-4)2013,,3: | 1 |
| 16 | A two-point, three-dimensional seismic ray tracing u- sing genetic algorithms 显示文摘 | Hetal S | 1999 | Physics of the Earth and Planetary Interiors1999,113,: | 1 |
| 17 | Quench detection of superconducting magnets using ultrasonic wave显示文摘 | Ninomiya A Sakaniwa K Kado Hetal | 1989 | IEEE Transactions on Magnet1989,25,2: | 1 |
| 18 | Complement Activation Regulates the capacity of proximal tubular epithelial cell to stimulate alloreactive T cell response显示文摘 | Ke LI Hetal Patel | 2004 | J Am Soc Nephrol2004,15,: | 1 |
| 19 | Monoclona lantibo dydefined phenoty pesofre gionall ymphno deandperi pheral blood lymphocybesu bpopula tionsinear lybreastcancer 显示文摘 | Morton BA Ramey WG Paderon Hetal | 1986 | CancerRes1986,46,: | 1 |
| 20 | A simple effieient method for realistic animation of cloud显示文摘 | Dobashi Y Kaneda K Hamashima Hetal | 2000 | Acm siggraph2000,,7: | 1 |