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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | FXR: a metabolic regulator and cell protector显示文摘Farnesoid X 受体(FXR ) 是激活 ligand 的抄写因素的原子受体总科的一个成员。作为一个新陈代谢的管理者, FXR 戏在胆汁酸,胆固醇,类脂化合物,和葡萄糖新陈代谢给角色调音。因此, FXR 是为很多新陈代谢的混乱的一个潜在的药目标,特别那些与新陈代谢的症候群有关。更最近,我们的组和其它扩大了 FXR 的功能到非常新陈代谢的规定,它在肠,肝新生,和 hepatocarcinogenesis 包括抗菌剂生长。这些新调查结果比以前想建议 FXR 有宽广得多的角色,并且也为多重疾病作为一个药目标加亮 FXR。这评论总结 FXR 的基本信息,但是集中于它的新功能。 | Yan-Dong Wang Wei-Dong Chen David D Moore Wendong Huang | 2008 | Cell Research2008，18，11： | 33 |
| 3 | 桥梁健康监测应用与研究现状(英文)显示文摘桥梁损伤诊断与健康监测是近年来国际上的研究热点 ,在实践方面 ,土木工程和航空航天工程、机械工程有明显的差别 ,比如桥梁结构以及其他大多数土木结构 ,尺寸大、质量重 ,具有较低的自然频率和振动水平 ,桥梁结构的动力响应极容易受到不可预见的环境状态、非结构构件等的影响 ,这些变化往往被误解为结构的损伤 ,这使得桥梁这类复杂结构的损伤评估具有极大的挑战性 .本文首先给出了结构健康监测系统的定义和基本构成 ,然后集中回顾和分析了如下几个方面的问题 :①损伤评估的室内实验和现场测试 ;②损伤检测方法的发展 ,包括 :(a)动力指纹分析和模式识别方法 ,(b)模型修正和系统识别方法 ,(c)神经网络方法 ;③传感器及其优化布置等 ,并比较和分析了各自方法的优点和不足 .文中还总结了健康监测和损伤识别在桥梁工程中的应用 ,指出桥梁健康监测的关键问题在于损伤的自动检测和诊断 ,这也是最困难的问题 ; | 宗周红 WANG T L HUANG D Z 郑振飞 | 2002 | 福州大学学报(自然科学版)2002，30，2： | 18 |
| 4 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 5 | 通过监测乙型肝炎患者耐药突变株比例的变化推测cccDNA的快速更新周期显示文摘【据Hepatology 2021年1月报道】题:通过监测乙型肝炎患者耐药突变株比例的变化推测ccc DNA的快速更新周期(作者Huang Q等)来自南方医科大学南方医院的孙剑教授课题组利用两项已结束的随机对照临床研究样本,以拉米夫定耐药(LAMR)突变位点—rt M204I/V作为标记,以rt M204I/V耐药株相对于野毒株的比例变化,推测ccc DNA池的更新周期。 | 陆星宇 周彬孙 HUANG Q ZHOU B CAI D | 2021 | 临床肝胆病杂志2021，37，4： | 16 |
| 6 | Status monitoring and health assessment of Luhuitou fringing reef of Sanya, Hainan, China显示文摘The monitoring survey and health assessment for benthic community were carried out in Luhuitou fringing reef of Sanya, Hainan, China in 2002. Monitoring survey included manta tow, line intercept transect, video transect and digital photograph. The mean live coral cover was 23.40%. Comparison of used monitoring methods showed that video transect can replace line intercept transect, and 50 m transect is better than 20 m transect in uneven coral region. Survey data and comparison with previous research work showed that Luhuitou fringing reef has been damaged severely and has a general declining trend with live coral cover from about 85% in the 1960s down to 20% in 2004, but it still has quite high biodiversity and therefore has special protection value. Main factors of Luhuitou fringing reef declining were human activities including reef rock digging and curios collecting, destructive fishing, sediment and pollutant from coastal land, and recent marine aquaculture. Only strengthening integrated management can reach improvement and restoration of Luhuitou declining coral reef ecosystem. | ZHANG Qiaomin SHI Qi CHEN Gang FONG T C W WONG D C C HUANG Hui WANG Hankui ZHAO Meixia | 2006 | Chinese Science Bulletin2006，51，B12： | 15 |
| 7 | Clostridium difficile infections in China显示文摘Clostridium difficile (C. difficile) infection has become one of the major hospital-associated infections in West-ern countries in the last two decades. However, there is limited information on the status of C. difficile infection inChinese healthcare settings. Given the large and increasing elderly population and the well-recognized problem ofover-prescribing of broad spectrum antibiotics in China, it is critical to understand the epidemiology and potentialrisk factors that may contribute to C. difficile infection in China. A literature review of available published studies,including those in Chinese language-based journals, was conducted. A review of the currently available literaturesuggested the presence of C. difficile infections in China, but also suggested that these infections were not particu-larly endemic. This finding should lead to better designed and greatly expanded studies to provide a more reliableepidemiologically-based conclusion on the actual status of C. difficile infection in China, including the identifica-tion of any associated risk factors. Such information is ultimately valuable to develop appropriate strategies to pre-vent C. difficile infection and the vast negative impact of such infections in China and other developing countries. | Ke Jin a,b,c,Shixia Wang c,d,Zuhu Huang a,b,c,Shan Lu b,c,daDepartment of Infectious Diseases,bJiangsu Province Key Laboratory in Infectious Diseases,cChina-US Vaccine ResearchCenter,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China d Department of Medicine,University of Massachusetts Medical School,Worcester,MA 01655,USA. | 2010 | The Journal of Biomedical Research2010，24，6： | 14 |
| 8 | Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction显示文摘Zika 病毒(ZIKV ) 的最近的爆发为治疗学加亮迫切需要。朊酶建筑群 NS2B-NS3 在 flaviviral polyprotein 处理期间起必要作用,并且因此代表一个吸引人的药目标。这里,我们开发了裂口酶识别直接指向 flavivirus NS2B-NS3 相互作用的 orthosteric 禁止者的基于互补的高产量的屏蔽试金。由屏蔽一个总数 2 816 同意了并且 investigational 药,我们识别了三个有势力候选人, temoporfin, niclosamide,和 nitazoxanide,,有 nanomolar 力量的 flavivirus NS2B-NS3 相互作用禁止者。显著地,在老鼠的在人的胎盘、神经的祖先房间的大多数有势力化合物, temoporfin,不是仅仅禁止的 ZIKV 复制,而且阻止的导致 ZIKV 的 viremia 和死亡当模特儿。结构的停靠建议 temoporfin 潜在地绑保持批评 NS2B 残余的 NS3 衣袋,因此禁止以一种非竞争的方式处理的 flaviviral polyprotein。当这些药已经在 USA 或另外的国家在另外的指示任何一个为临床的使用被同意了,他们由 ZIKV 和另外的 flaviviruses 为感染的管理代表有希望、容易开发的治疗。 | Zhong Li Matthew Brecher Yong-Qiang Deng Jing Zhang Srilatha Sakamuru Binbin Liu Ruili Huang Cheri A Koetzner Christina A Allen Susan A Jones Haiying Chen Na-Na Zhang Min Tian Fengshan Gao Qishan Lin Nilesh Banavali Jia Zhou Nathan Boles Menghang Xia Laura D Kramer Cheng-Feng Qin Hongmin Li | 2017 | Cell Research2017，27，8： | 11 |
| 9 | Subclinical atherosclerosis in northern and southern China: the Chinese paradox显示文摘背景冠的心疾病(CHD ) 的发生是更高的在北比在南部的中国,然而,在传统的 CHD 的差别冒险的,解释这。没有学习在可以帮助在发生解释差别的无临床症状的动脉粥样硬化检验了差别。这研究为在北、南部的中国之间的石灰化用冠的计算断层摄影术(CT ) 在无临床症状的动脉粥样硬化检验了这些差别。我们在一个大多中心选择了参加者的一件随机的样品的方法为冠的钙在一个北城市(诺思) 里扫描的进行中的流行病的学习(北京, n = 49 ) 并且在二个南部的城市(南方) 里(上海, n = 50,并且广州, n = 50 ) 。从三个领域中心的参加者(意味着年龄 67 年) 经历了用动脉粥样硬化扫描的多种族的学习为冠的钙测量扫描的冠的风险因素评估和心脏的 CT 协议。结果调整了在诺思中国(北京) 的转变木头的冠的动脉钙 20 是 3.1 +/-0.4 并且在华南(上海和广州) 是 2.2 +/- 0.3 (P = 0.04 ) 。为北京的北城市的吝啬的钙分数比广州的南部的城市的高三倍(P = 0.01 ) 并且比为上海的南部的城市高 2.5 倍(P = 0.03 ) 。结论无临床症状的动脉粥样硬化的程度在广州和上海的二个南部的城市里比那在北京的北城市里是显著地更高的,甚至在为标准心脏的风险因素调整以后。这发现建议标准风险因素充分不在临床的 CHD 发生解释北方南方差别。 | Jie Huang Yang-Feng Wu Xiao-Qing Liu Ding Ding Lian-Cheng Zhao Bin Lu Xian Li Nathan D Wong Laurie D Dustin Stanley P Azen Robert C Detrano | 2011 | Journal of Geriatric Cardiology2011，8，2： | 7 |
| 10 | IFN-a production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and-independent pathways显示文摘Understanding the defense mechanisms of the host of an organism is important for infection control.In previous studies,we demonstrated that interferon-a(IFN-a),but not IL-12,was produced by human peripheral blood mononuclear cells infected with varicella-zoster virus(VZV).Here,we investigated what kind of cell(s)and which signal molecule(s)are involved in IFN-a production.Using cell isolation and ELISA,we found that plasmacytoid dendritic cells(pDCs)were responsible for IFN-a production during VZV infection.We also found that Toll-like receptor 9(TLR9)was involved in VZV-induced IFN-a production because inhibitory CpG oligodeoxynucleotide inhibited IFN-a production.UV-inactivated VZV-induced IFN-a production was lower than that of active VZV,indicating another TLR9-independent pathway.Further studies demonstrated that double-stranded RNA-dependent protein kinase,but not DNA-dependent protein kinase was involved in VZV-induced IFN-a production.Together,these results suggest that pDCs play an important role in IFN-a production during VZV infection through TLR9-dependent and-independent pathways. | Hong-Ren Yu Hsin-Chun Huang Ho-Chang Kuo Jiunn-Ming Sheen Chia-Yo Ou Te-Yao Hsu Kuender D Yang | 2011 | Cellular & Molecular Immunology2011，8，2： | 7 |
| 11 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 12 | Microbial biomass, N mineralization and nitrification, enzyme activities, and microbial community diversity in tea orchard soils显示文摘 | Xue D Yao HY Huang CY | 2007 | 中国生物学文摘2007，21，8： | 6 |
| 13 | Genome resequencing and transcriptome profiling reveal structural diversity and expression patterns of constitutive disease resistance genes in Huanglongbing-tolerant Poncirus trifoliata and its hybrids显示文摘Huanglongbing(HLB)is the most destructive bacterial disease of citrus worldwide.While most citrus varieties are susceptible to HLB,Poncirus trifoliata,a close relative of Citrus,and some of its hybrids with Citrus are tolerant to HLB.No specific HLB tolerance genes have been identified in P.trifoliata but recent studies have shown that constitutive disease resistance(CDR)genes were expressed at much higher levels in HLB-tolerant Poncirus hybrids and the expression of CDR genes was modulated by Candidatus Liberibacter asiaticus(CLas),the pathogen of HLB.The current study was undertaken to mine and characterize the CDR gene family in Citrus and Poncirus and to understand its association with HLB tolerance in Poncirus.We identified 17 CDR genes in two citrus genomes,deduced their structures,and investigated their phylogenetic relationships.We revealed that the expansion of the CDR family in Citrus seems to be due to segmental and tandem duplication events.Through genome resequencing and transcriptome sequencing,we identified eight CDR genes in the Poncirus genome(PtCDR1-PtCDR8).The number of SNPs was the highest in PtCDR2 and the lowest in PtCDR7.Most of the deletion and insertion events were observed in the UTR regions of Citrus and Poncirus CDR genes.PtCDR2 and PtCDR8 were in abundance in the leaf transcriptomes of two HLB-tolerant Poncirus genotypes and were also upregulated in HLB-tolerant,Poncirus hybrids as revealed by real-time PCR analysis.These two CDR genes seem to be good candidate genes for future studies of their role in citrus-CLas interactions. | Nidhi Rawat Brajendra Kumar Ute Albrecht Dongliang Du Ming Huang Qibin Yu Yi Zhang Yong-Ping Duan Kim D Bowman Fred G Gmitter Jr Zhanao Deng | 2017 | Horticulture Research2017，4，1： | 5 |
| 14 | High efficiency, high power 808nm laser array and stacked arrays optimized for elevated temperature operation显示文摘Operation of 808-nm laser diode pumping at elevated temperature is crucial to many applications. Reliable operation at high power is limited by high thermal load and low catastrophic optical mirror damage (COMD) threshold at elevated temperature range. We demonstrated high efficiency and high power operation at elevated temperature with high COMD power. These results were achieved through device design optimization such as growth conditions, doping profile, and materials composition of the quantum-well and other layers. Electrical-to-optical efficiency as high as 62% was obtained through lowered threshold current, lowered series resistance and increased slope efficiency. The performance of single broad-area laser diodes scales to that of high power single bars on water-cooled copper micro-channel heatsinks or conductively-cooled CS heatsinks. No reduction in bar performance or significant spectral broadening is seen when these micro-channel coolers are assembled into 6-bar and 18-bar CW stacks for the highest power levels. | Crump P A Crum T R DeVito M Farmer J Grimshaw M Huang Z Igl S A Macomber S Thiagarajan P Wise D | 2004 | 光机电信息2004，21，6： | 4 |
| 15 | 金刚石中的冰-Ⅶ相包裹体:来自地球深部地幔的含水流体证据显示文摘水在地球内部不同圈层的存在形态、分布、含量以及全球水循环一直以来都是固体地球科学研究的前沿热点问题之一。冰-Ⅶ相作为水的一种高压相,目前已经被国际矿物学会认定为一种新矿物。 | Tschauner O Huang S Greenberg E Prakapenka V B Rossman G R Shen A H Zhang D Newville M Lanzirotti A Tait K 张宝华 | 2018 | 矿物岩石地球化学通报2018，37，6： | 4 |
| 16 | Analysis of CO_2 utilization into synthesis gas based on solar thermochemical CH_4-reforming显示文摘In this study, the solar thermochemical reactor performance for CO_2 utilization into synthesis gas(H_2+ CO) based on CH_4 reforming process was investigated in the context of carbon capture and utilization(CCU) technologies. The P1 radiation heat transfer model is adopted to establish the heat and mass transfer model coupled with thermochemical reaction kinetics. The reactor thermal behavior with direct heat transfer between gaseous reactant and products evolution and the effects of different structural parameters were evaluated. It was found that the reactor has the potential to utilize by ~60% of CO_2 captured with 40% of CH_4 co-fed into syngas(72.9% of H_2 and 27.1% of CO) at 741.31 k W/mof incident radiation heat flux. However, the solar irradiance heat flux and temperature distribution were found to significantly affect the reactant species conversion efficiency and syngas production. The chemical reaction is mainly driven by the thermal energy and higher species conversion into syngas was observed when the temperature distribution at the inner cavity of the reactor was more uniform. Designed a solar thermochemical reactor able to volumetric store concentrated irradiance could highly improve CCU technologies for producing energy-rich chemicals. Besides, the mixture gas inlet velocity, operating pressure and CO_2/CH_4 feeding ratio were crucial to determining the efficiency of CO_2 utilization to solar fuels. Catalytic CO_2-reforming of CH_4 to chemical energy is a promising strategy for an efficient utilization of CO_2 as a renewable carbon source. | Bachirou Guene Lougou Yong Shuai Gédéon Chaffa Huang Xing Heping Tan Huibin Du | 2019 | Journal of Energy Chemistry2019，28，1： | 4 |
| 17 | Diaporthe species occurring on citrus in China显示文摘Diaporthe species are important pathogens of a wide range of hosts including many economically important crops.Diaporthe citri is generally accepted to cause melanose of Citrus fruits,leaves and shoots;stem-end rot of fruits and gummosis of perennial branches.In this study,147 strains of Diaporthe were isolated from diseased leaves,twigs,fruits and branches of Citrus from Shaanxi,Zhejiang,Guangxi,Fujian,Guangdong,Jiangxi,Hunan,Chongqing and Shanghai and identified by morphology and molecular analysis of nuclear ribosomal internal transcribed spacer(ITS),partial sequences of translation elongation factor 1-α(EF 1-α),tubulin(TUB)and calmodulin(CAL)genes.All strains from Citrus clustered in three clades.Diaporthe citri was the predominant species and is compared with strains from Florida,USA,where this species was first collected and described.Two new taxa differing from D.citri are described as D.citriasiana and D.citrichinensis in this paper.Inoculation tests indicate that all three species are able to cause stem-end rot of fruits,while only D.citri could cause melanose on leaves. | Feng Huang Xin Hou Megan M Dewdney Yushi Fu Guoqing Chen Kevin D Hyde Hongye Li | 2013 | Fungal Diversity2013，，4： | 4 |
| 18 | Comparison of HER-2/neu,ER and PCNA expression in premenopausal and postmenopausal patients with breast carcinoma显示文摘 | Zheng W Zheng J Ma L Meng F Huang L Ma D | 2005 | 第二军医大学学报2005，26，8： | 4 |
| 19 | 血浆7-酮胆固醇与冠状动脉疾病患者心血管结局和总死亡率的关系显示文摘7-酮胆固醇(7-ketocholesterol,7-KC)是胆固醇氧化产物的一种形式,在动物动脉粥样硬化模型的形成中起重要作用。该文研究人员试图确定循环7-KC与稳定型冠状动脉疾病(coronary artery disease,CAD)患者的临床心血管结局和总死亡率的关系。 | 刘莉 叶鹏 Song J Wang D Chen H Huang X Zhong Y Jiang N Chen C Xia M | 2017 | 中华高血压杂志2017，25，6： | 4 |
| 20 | Pathotypes and Genetic Diversity of Chinese Collections of Elsinoě fawcettii Causing Citrus Scab显示文摘Two scab diseases are currently recognized on citrus: citrus scab, caused by El sino? fawcettii, and sweet orange scab, caused by E. australis. Although these pathogens are economically important, there is no molecular data on these species in China. Here we use internal transcribed spacer sequence data to report on host-specificity and genetic relationships among 46 isolates collected from the main citrus varieties grown across China. All strains isolated were E. fawcettii. Based on pathogenicity testing on 9 diffe rent citrus species, isolates were divided into 11 path otypes(SM, FBHR, SJCR, SPOJCR, SR, SOJG, SPOJC, SRGC, Lemon and two unnamed pathotypes). SM is a new pathotype, and two isolates did not fit into any of the known pathotypes of E. fawcettii. Inter-simple sequence repeat(ISSR-PCR) assays separated the E. fawcettii isolates into 10 subgroups; the groupings basically corresponded to the pathogenicity test. | HOU Xin HUANG Feng ZHANG Tian-yuan XU Jian-guo Hyde D Kevin LI Hong-ye | 2014 | Journal of Integrative Agriculture2014，13，6： | 4 |
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