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| 1 | 曹雪涛院士科研团队论文荣膺中国百篇最具影响国际学术论文--长链非编码RNA1nc-DC通过STAT3调控人DC的分化和功能显示文摘树突状细胞(DC)是免疫系统中重要的抗原提呈细胞,其成熟和功能状态决定着免疫应答的走向和强度。哺乳动物基因组能够转录产生大量的长链非编码RNA(long noncoding RNA,IncRNA),其在免疫系统中的功能还知之甚少。
曹雪涛院十科研团队王品副教授课题组采用了转录组芯片二代测序高通量筛选方法、RNA-pulldown、ChIP-seq等技术展开了对IncRNA在DC分化和功能中作用的研究,发现并鉴定了特异性高表达于DC的1ncRNA,命名为1nc-DC,其可通过抑制STAT3去磷酸化,从而促进DC分化和功能。该研究成果发表于Science杂志[2014,344(6181):310-313],并于2015年12月被评为“中国百篇最具影响国际学术论文”。 | wang p xue y han y lin l wu c xu s jiang z xu j liu q cao x | 2016 | 中国肿瘤生物治疗杂志2016，23，1： | 10 |
| 2 | Assessment of erosion haz- ard with the USLE and GIS A ease study of the Upper Ewaso Nglro North basin of Kenya显示文摘 | Bancy M Mati Royston P C Morgan Francis N Gichuki John N Quinton Tim R Brewer Hans P l iniger | 2000 | lnternation Journal of Applied Earth Ob- servation and Geoinformation2000，2，2： | 1 |
| 3 | Simultaneous Shift and Carbon Dioxide Separation for the Direct Production of Hydrogen显示文摘 | Han C Harrison D P | | 0，，24： | 1 |
| 4 | A high-throughput Agrobacterium mediated transformation system for the grass model species Brachypodium distachyon L显示文摘 | Daniel I P Hans T C Klaus K N | 2008 | Transgenie Re search2008，17，： | 1 |
| 5 | Preparation of Greenberger-Horne-Zeilinger entangled states with multiple superconducting quantum-interference device qubits or atoms in cavity QED显示文摘 | Han S | 2004 | Phys Rev A2004，70，06： | 1 |
| 6 | Microbial degradation of quinQline by immobilized cells of Burkholderia pickettii 显示文摘 | Wang J L Quan X C Han L P | 2002 | Water Res2002，36，9： | 1 |
| 7 | Efficient transformation of Actinidia arguta by reducing the strength of basal salts in the medium to alleviate callus browning显示文摘 | Han M L Gleave A P Wang T C | 2010 | Plant B iotechnology Reporter2010，4，： | 1 |
| 8 | Controlling eutrophication: Nitrogen and phosphorus显示文摘 | Daniel J C Hans W P Robert W H | 2009 | Science2009，323，20： | 1 |
| 9 | The short form of the alternatively spliced flt-4 but not its ligand vascular endothelial growth factoa C is related to lymph node mestasis in homan breast cancer显示文摘 | Gunningham S P Currie M J Han C | 2000 | Clin Cancer Res2000，6，11： | 1 |
| 10 | Ho:Tm lasers Ⅱ:experiments,IEEE显示文摘 | LEE C J HAN G BARNES N P | 1996 | Journal of Quantum Electrics1996，32，1： | 1 |
| 11 | The cementogenic differentiation of periodontal ligament cells via the activation of WntlB-catenin signalling pathway by Li' ions released from bioactive scaffolds显示文摘 | Han P Wu C Chang J | 2012 | Bio?materials2012，33，27： | 1 |
| 12 | Effect of film-hole shape on turbine-blade heat-transfer coefficient distribution 显示文摘 | TENG S HAN J C POINSATTE P E | 2001 | Jour- nal of Thermophysics and Heat Transfer2001，15，3： | 1 |
| 13 | The effect of dehydration and ion stress on carbon dioxide fixation in drought-tolerant phototrophic micro-organisms 显示文摘 | Ben De W Hans C P W Luuc R M | 1990 | FEMS Microhiol Lett1990，74，1： | 1 |
| 14 | Inclined Load Capacity of Suction Caissons 显示文摘 | Aubeny C P Han S W Murff J D | 2003 | International Journal for Numerical and Analytical Methods in Geomechanics2003，27，： | 1 |
| 15 | Bone dowels in anterior lumbar interbody fusion显示文摘 | Lekovic G P Han P P Kenny K J Dickman C A | 2007 | J Spinal Disord Tech2007，20，： | 1 |
| 16 | Efficient many-party controlled teleportation of multiqubit quantum informatin via entanglement显示文摘 | YANG C P CHU S J HAN S Y | 2004 | Physical Review A2004，70，02： | 1 |
| 17 | Facile Synthesis of Li4Ti5 O1JC Composite with Super Rate Performance 显示文摘 | LIB H HAN C P HE Y B | 2012 | En- ergy & Environmental Science2012，5，11： | 1 |
| 18 | ' Synthesis, characterization, and activity of visible-light-driven nitrogen-Doped TiO2-SiO2 mixed oxide photocatalysts 显示文摘 | ~k~qG T P Toll C S HAN Y F | 2009 | J Phys Chem C2009，113，10： | 1 |
| 19 | Effect of thermal history on the rheological behavior of thermoplastic polyurethanes显示文摘 | Yoon P J Han C D | 2000 | Macromolecules2000，33，： | 1 |
| 20 | Heat transfer and pressure drop correlations for square channels with 45 deg ribs at high Reynolds numbers显示文摘 | Rallabandi A P Yang H T Han J C | 2009 | Journal of Heat Trans- fer2009，131，7： | 1 |
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