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| 1 | Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro显示文摘Gastrin and cyclooxygenase-2(COX-2) playimportant roles in the carcinogenesis and progression ofgastric cancer.However,it remains unknown whether the combination of cholecystokinin-2(CCK-2) receptor antagonist plus COX-2 inhibitor exerts synergistic anti-tumor effects on human gastric cancer.Here,we demonstrated that the combination of AG-041R(a CCK-2 receptor antagonist) plus NS-398(a selective COX-2 inhibitor) treatment had synergistic effects on proliferation inhibition,apoptosis induction,down-regulation of Bcl-2 and up-regulation of Bax expression in MKN-45 cells.These results indicate that simultaneous targeting of CCK-2 receptor and COX-2 may inhibit gastric cancer development more effectively than targeting either molecule alone.(C)2008 Elsevier Ireland Ltd.All rights reserved. | Sun, W. H. | 2008 | 南京医科大学学报(自然科学版)2008,28,9: | 30 |
| 2 | Schistosoma japonicum egg antigens stimulate CD4(+) CD25(+) T cells and modulate airway inflammation in a murine model of asthma显示文摘 | Yang, J. H. Zhao, J. Q. Yang, Y. F. Zhang, L. Yang, X. Zhu, X. Ji, M. J. Sun, N. X. Su,C. | 2007 | 南京医科大学学报(自然科学版)2007,27,4: | 25 |
| 3 | Mathematical modeling and full-scale shaking table tests for multi-curve buckling restrained braces显示文摘自从他们在 1970 年代被介绍,弄弯制止的背带(BRB ) 广泛地在地震缓解被使用了。然而,传统的 BRB 把几劣势被使用一个钢试管包臼阻止核心板弄弯引起了,例如:在生产进程期间的在使用的材料之间的复杂接口,不明确的精确,和时间消费。在这研究,称为弄弯制止的钩住(MC-BRB ) 的多曲线的一台新设备被建议克服这些劣势。新设备由一个核心盘子组成,多重颈部分集合了形成多重精力阻止 BRB 弄弯的驱散片断,和扩大片断,侧面的支持元素和抑制元素。位于核心板的中间的扩大片断能被焊接到侧面的支持并且抑制元素增加弄弯抵抗并且阻止他们在地震期间滑动。与 MC-BRBs 装备的照原尺寸的钢结构上的部件测试和一系列摇晃的桌子测试被执行为地震缓解调查这个新 BRB 图案的行为和能力。试验性的结果说明 MC-BRB 在周期的装载下面拥有稳定的机械行为并且在地震期间提供好保护给结构。另外,一个数学模型被开发了模仿 BRB 的机械特征。 | C. S. Tsai Yungchang Lin Wenshin Chen H. C. Su | 2009 | Earthquake Engineering and Engineering Vibration2009,8,3: | 8 |
| 4 | Schistosoma japonicum egg antigens stimulate CD4(+) CD25(+) T cells and modulate airway inflammation in a murine model of asthma显示文摘 | Yang, J. H. Zhao, J. Q. Yang, Y. F. Zhang, L. Yang, X. Zhu, X. Ji, M. J. Sun, N. X. Su, C. | 2007 | 南京医科大学学报(自然科学版)2007,27,5: | 4 |
| 5 | Effects of dietary selenite, copper, and zinc on tissue trace mineral levels in chicks显示文摘 | G. F. Combs Q. Su C. H. Liu S. B. Combs | 1986 | Biological Trace Element Research1986,,1: | 1 |
| 6 | Late gadolinium enhancement: precursor to cardiomyopathy in Duchenne muscular dystrophy?显示文摘 | Michael D. Puchalski Richard V. Williams Bojana Askovich C. Todd Sower Kan H. Hor Jason T. Su Nathan Pack Edward Dibella William M. Gottliebson | 2009 | The International Journal of Cardiovascular Imaging2009,,1: | 1 |
| 7 | Clinicopathological differences of laterally spreading tumors of the colorectum according to gross appearance显示文摘 | B. Kim H. Chang K. Su Han D. Sohn C. Hong J. Park S.-C. Park H. Choi J. Oh | 2011 | Endoscopy2011,,02: | 1 |
| 8 | High Prevalence of Latent Tuberculosis Infection in Patients in End-Stage Renal Disease on Hemodialysis: Comparison of QuantiFERON-TB GOLD, ELISPOT, and Tuberculin Skin Test显示文摘 | S. S. J. Lee K. J. Chou I.J. Su Y. S. Chen H. C. Fang T. S. Huang H. C. Tsai S. R. Wann H. H. Lin Y. C. Liu | 2009 | Infection2009,,2: | 1 |
| 9 | Electron-beam welding behavior in Mg-Al-based alloys显示文摘 | S. F. Su H. K. Lin J. C. Huang N. J. Ho | 2002 | Metallurgical and Materials Transactions A2002,,5: | 1 |
| 10 | Electron-beam welding behavior in Mg-Al-based alloys显示文摘 | S. F. Su H. K. Lin J. C. Huang N. J. Ho | 2002 | Metallurgical and Materials Transactions A2002,,5: | 1 |
| 11 | Lysogenic infection of a Shiga toxin 2-converting bacteriophage changes host gene expression, enhances host acid resistance and motility显示文摘 | L. K. Su C. P. Lu Y. Wang D. M. Cao J. H. Sun Y. X. Yan | 2010 | Molecular Biology2010,,1: | 1 |
| 12 | Biologic and genetic comparison of Toxoplasma gondii isolates in free-range chickens from the northern Pará state and the southern state Rio Grande do Sul, Brazil revealed highly diverse and distinct parasite populations显示文摘 | J.P. Dubey N. Sundar S.M. Gennari A.H.H. Minervino N.A. da R. Farias J.L. Ruas T.R.B. dos Santos G.T. Cavalcante O.C. H. Kwok C. Su | 2006 | Veterinary Parasitology2006,,2: | 1 |
| 13 | Thermal diffusivity, thermal conductivity, and specific heat capacity measurements of molten tellurium显示文摘 | Shen Zhu C. Li Ching-Hua Su B. Lin H. Ban R.N. Scripa S.L. Lehoczky | 2002 | Journal of Crystal Growth2002,,1: | 1 |
| 14 | 4-1BB-based Isolation and Expansion of CD8+ T Cells Specific for Self-Tumor and Non–Self-Tumor Antigens for Adoptive T-cell Therapy显示文摘 | Beom K. Choi Sang C. Lee Myoung J. Lee Young H. Kim Young-Woo Kim Keun-Won Ryu Jun-Ho Lee Su M. Shin Sang-Ho Lee Susumu Suzuki Ho S. Oh Chang H. Kim Don G. Lee Sun H. Hwang Eun-Mi Yu In O. Lee Byoung S. Kwon | 2014 | Journal of Immunotherapy2014,,4: | 1 |
| 15 | QTL detection for eating quality of cooked rice in a population of chromosome segment substitution lines显示文摘 | X. Y. Wan J. M. Wan C. C. Su C. M. Wang W. B. Shen J. M. Li H. L. Wang L. Jiang S. J. Liu L. M. Chen H. Yasui A Yoshimura | 2004 | Theoretical and Applied Genetics2004,,1: | 1 |
| 16 | WITHDRAWN: A dynamic stiffness element for free vibration analysis of composite beams and its application to aircraft wings显示文摘 | J.R. Banerjee H. Su C. Jayatunga | 2007 | Advances in Engineering Software2007,,: | 1 |
| 17 | Expression of factor VII in the liver of patients with liver disease: correlations with the disease severity and impairment in the hemostasis显示文摘 | E. Rodríguez-I?igo J. Bartolomé J. A. Quiroga U. Hedner A. Suárez J. F. Tomás F. Manzarbeitia C. Arocena M. L. Manzano H. Oliva V. Carre?o | 2001 | Blood Coagulation and Fibrinolysis2001,,3: | 1 |
| 18 | Hepatitis C virus infection: a risk factor for P arkinson’s disease显示文摘 | W. Y.‐Y. Wu K.‐H. Kang S. L.‐S. Chen S. Y.‐H. Chiu A. M.‐F. Yen J. C.‐Y. Fann C.‐W. Su H.‐C. Liu C.‐Z. Lee W.‐M. Fu H.‐H. Chen H.‐H. Liou | 2015 | J Viral Hepat2015,,10: | 1 |
| 19 | Characteristics of norovirus gastroenteritis outbreaks in a psychiatric centre显示文摘 | C. Y. TSENG C. H. CHEN S. C. SU F. T. WU C. C. CHEN G. Y. HSIEH C. H. HUNG C. P. FUNG | 2010 | Epidemiology and Infection2010,,: | 1 |
| 20 | Calix[4]arene derivatives as stationary phases for capillary gas chromatography显示文摘 | L. Lin C. Y. Wu Z. Q. Yan X. Q. Yan X. L. Su H. M. Han | 1998 | Chromatographia (-)1998,,11: | 1 |