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| 1 | Wideband electromagnetic characteristics modeling and analysis of missile targets in ballistic midcourse显示文摘The wideband electromagnetic characteristics of missile targets in midcourse are the foundation of midcourse attack-defense confrontation.This paper proposes a novel electromagnetic scattering modeling method for midcourse targets based on a precise scattering center model,in which the nonideal scattering phenomenon,shielding effect and micro-motion are taken into consideration for the first time.Firstly,a precise scattering center model incorporating both the sliding scattering and anisotropic scattering is established.Then the change rule of the target attitude is generalized,and a checking method of the scattering center shielding effect is proposed for rotationally symmetric targets.Afterwards,a novel dynamic electromagnetic scattering model is presented,where the scattering center model updates along with the variation of the target attitude and can characterize the change of the electromagnetic characteristics of midcourse targets exactly.Finally,in light of the established model,the dynamic electromagnetic characteristics within different attitude angle bounds are analyzed by stages,and some useful conclusions are obtained.Experiment results from the measured data in anechoic chamber verify the validity of the proposed modeling method and relevant analysis. | XU ShaoKun LIU JiHong WEI XiZhang LI Xiang GUO GuiRong | 2012 | Science China(Technological Sciences)2012，55，6： | 11 |
| 2 | Parameter Estimation and Performance Analysis of Coherent Polarization Attributed Scattering Center Model显示文摘 | XU Shaokun WEI Xizhang LI Xiang GUO Guirong | 2013 | Chinese Journal of Electronics2013，22，1： | 9 |
| 3 | In-situ fabrication of particulate reinforced aluminum matrix composites under high-frequency pulsed electromagnetic field显示文摘Pulsed magnetic field is generated when imposing pulse signal on high-frequency magnetic field. Distribution of the inner magnetic intensity in induction coils tends to be uniform. Furthermore oscillation and disturbance phenomena appear in the melt. In-situ Al2O3 and Al3Zr particulate reinforced aluminum matrix composites have been synthesized by direct melt reaction using Al-Zr(CO3)2 components under a foreign field. The size of reinforced particulates is 2-3 μm. They are well distributed in the matrix. Thermodynamic and kinetic analysis show that high-frequency pulsed magnetic field accelerates heat and mass transfer processes and improves the kinetic condition of in-situ fabrication. | Guirong Li Yutao Zhao Qixun Dai Hongjie Zhang Hongming Wang | 2007 | Journal of University of Science and Technology Beijing2007，14，5： | 8 |
| 4 | High-efficiency and multiplex adenine base editing in plants using new TadA variants显示文摘Recently reported adenine base editors(ABEs)exhibit powerful potential for targeted gene correction as well as developing gain-of-function mutants and novel germplasms for both gene function studies and crop breeding.However,editing efficiency varies significantly among different target sites.Here,we investigated the activities of three evolved E.coli adenosine deaminase TadA variants(TadA8e,TadA8.17,and TadA8.20)side-by-side in transgenic rice.We found that TadA8e outperforms TadA8.17 and TadA8.20,and induces efficient A-to-G conversion at all tested sites in the rice genome,including those that were un-editable by ABE7.10 in our previous experiments.Furthermore,V82S/Q154R mutations were incorporated into TadA8e,resulting in a new variant that we named TadA9.Our data show that TadA9 is broadly compatible with CRISPR/SpCas9,CRISPR/SpCas9-NG,and CRISPR/SpRY,as well as CRISPR/ScCas9 nickase systems,achieving comparable or enhanced editing in a larger editing window at diverse PAM sites as compared with TadA8e.Finally,TadA9 was used to simultaneously install novel SNPs in four endogenous herbicide target genes in the commercial rice cultivar Nangeng 46 for potential field application in.weed control.Collectively,we successfully generated a series of novel ABEs that can efficiently edit adenosines in the rice genome.Our findings suggest that TadA9 and TadA8e have great potentials in the development of plant base editors and crop molecular breeding. | Daqi Yan Bin Ren Lang Liu Fang Yan Shaofang Li Guirong Wang Wenxian Sun Xueping Zhou Huanbin Zhou | 2021 | Molecular Plant2021，14，5： | 8 |
| 5 | A nonlinear POD reduced order model for limit cycle oscillation prediction显示文摘As the amplitude of the unsteady flow oscillation is large or large changes occur in the mean background flow such as limit cycle oscillation,the traditional proper orthogonal decomposition reduced order model based on linearized time or frequency domain small disturbance solvers can not capture the main nonlinear features.A new nonlinear reduced order model based on the dynamically nonlinear flow equation was investigated.The nonlinear second order snapshot equation in the time domain for proper orthogonal decomposition basis construction was obtained from the Taylor series expansion of the flow solver.The NLR 7301 airfoil configuration and Goland+ wing/store aeroelastic model were used to validate the capability and efficiency of the new nonlinear reduced order model.The simulation results indicate that the proposed new reduced order model can capture the limit cycle oscillation of aeroelastic system very well,while the traditional proper orthogonal decomposition reduced order model will lose effectiveness. | CHEN Gang *,LI YueMing & YAN GuiRong MOE Key Laboratory for Strength & Vibration,College of Aerospace,Xi’an Jiaotong University,Xi’an 710049,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，7： | 7 |
| 6 | Big data-enabled multiscale serviceability analysis for aging bridges显示文摘 | Yu Liang Dalei Wu Guirong Liu Yaohang Li Cuilan Gao Zhongguo John Ma Weidong Wu | 2016 | Digital Communications and Networks2016，2，3： | 5 |
| 7 | Nonuniform stretch processing for the range profile of a target with micro-motion显示文摘Complex motions such as micro-motions induce complex range-Doppler coupling effect in radar imaging. Hence, it is a challenge to reconstruct a clear range profile of a target with micro-motion. Stretch processing with fine motion compensation cannot perform well while it ties to eliminate the distortion of range profile caused by Doppler effect, because it is difficult to accurately estimate each scattering center velocity during coherent processing interval. Based on nonuniform stretch processing (NSP), a new technology is proposed to decouple range, time and Doppler and then achieve range profile of target with micro-motion. The new technology uses a new synthetic wide-band waveform and has an innovative mathematic interpretation. Statistical properties of the new approach are primarily examined. Typical models of target with micro-motion for high resolution radar are presented. Monte Carlo simulations demonstrate the performance of the new technology and the simulation results confirm our expectations. | CHEN Hangyong JIANG Weidong LIU Yongxiang LI Xiang GUO Guirong | 2006 | Progress in Natural Science:Materials International2006，16，11： | 4 |
| 8 | Role of helicity of a-helical antimicrobia peptides to improve specificity显示文摘 | Yibing Huang Liyan He Guirong Li Naicui Zhai Hongyu Jiang Yuxin Chen | 2014 | Protein & Cell2014，5，8： | 3 |
| 9 | Synthesis, Antitumor Activity and Preliminary Structure-activity Relationship of 2-Aminothiazole Derivatives显示文摘In this paper, we described the synthesis of 2-aminoflfiazole sublibrary containing methyl, bromo, phenylor butylidene at 4- or/and 5-position of its core. All target compounds were evaluated tbr their antitumor activitiesagainst human lung cancer cell line H1299 and human glioma cell line SHG-44. Among the compotmds screened,4,5,6,7-tetrahydrobenzo[d]thiazole(26b) exhibited the most potent antittunor activities with IC50 values of 4.89 and4.03 μmol/L against the two tested cell lines, respectively. Preliminary structure-activity relationship(SAR) studies ofthese compound were subsequently investigated. | LI Hongshuang WANG Xinran DUAN Guiyun XIA Chengcai XIAO Yuliang LI Furong GE Yanqing YOU Guirong HAN Junfen FU Xiaopan | 2016 | Chemical Research in Chinese Universities2016，32，6： | 3 |
| 10 | Urban-rural disparities in mild cognitive impairment and its functional subtypes among community- dwelling older residents in central China显示文摘background Substantial variations in the prevalence of mild cognitive impairment(MCI)and its subtypes have been reported,although mostly in geographically defined developed countries and regions.Less is known about MCI and its subtypes in rural areas of less developed central China.Aims The study aimed to compare the prevalence of MCI and its subtypes in residents aged 65 years or older in urban and rural areas of Hubei Province,China.Methods Participants aged 65 years or older were recruited between 2018 and 2019.Inperson structured interviews and clinical and neuropsychological assessments were performed at city health community centres and township hospitals.results Among 2644 participants without dementia,735 had MCI,resulting in a prevalence of 27.8%for total MCI,20.9%for amnestic MCI(aMCI)and 6.9%for non-amnestic MCI(naMCI).The prevalence of MCI in urban and rural areas was 20.2%and 44.1%,respectively.After adjusting for demographic factors,the prevalence of total MCI,aMCI and naMCI differed significantly between rural and urban areas(adjusted odds ratio(OR)2.10,1.44 and 3.76,respectively).Subgroup analysis revealed an association between rural socioeconomic and lifestyle disadvantage and MCI and its subtypes.Conclusions Our findings suggest that the prevalence of MCI among urban residents in central China is consistent with that in other metropolis areas,such as Shanghai,but the prevalence in rural areas is twice that in urban areas.Prospective studies and dementia prevention in China should focus on rural areas. | Dan Liu Lin Li Lina An Guirong Cheng Cong Chen Mingjun Zou Bo Zhang Xuguang Gan Lang Xu Yangming Ou Qingming Wu Ru Wang Yan Zeng | 2021 | General Psychiatry2021，34，5： | 3 |
| 11 | The Sinorhizobium meliloti LysR family transcriptional factor LsrB is involved in regulation of glutathione biosynthesis显示文摘谷胱甘肽,在 Sinorhizobium meliloti 的一种关键抗氧化剂,为苜蓿(Medicago sativa ) 的发展被要求修理氮的小瘤。这 tripeptide 能被两 -glutamyl 半胱氨酸合成酶(GshA ) 和谷胱甘肽合成酶(GshB ) 在 Escherichia coli 和 S 综合。meliloti。基因证据显示了 S 的空异种。meliloti gshA 或 gshB1 不在苜蓿上建立有效共生。然而, gshA 和 gshB 的 transcriptional 规定很好没被理解。这里, S。meliloti LsrB, LysR 家庭 transcriptional 因素的一个成员,被发现断然由在免费生活、共生的条件下面激活 gshA 和 gshB1 的抄写调整谷胱甘肽生合成。在在 lsrB 在里面框架删除异种(lsrB1-2 ) 的谷胱甘肽生产的减少被使用四极 time-of-flight 液体层析团 spectrometry 决定。gshA 和 gshB1 的表示被即时量的反向的抄写聚合酶链反应和 promoter-GUS 熔化的分析相应地在免费生活、共生的条件下面在异种减少。有趣地, LsrB 断然调整了 oxyR 的抄写,它编码 LysR 家庭管理者的另一个成员并且在 S 对氧化压力作出回应。meliloti。oxyR 0 异种生产了更少的谷胱甘肽, gshA 的抄写在是一致地下面调整的。这些调查结果证明谷胱甘肽生合成被 LsrB 和 OxyR 断然在 S 调整。meliloti。 | Dawei Lu Guirong Tang Dong Wang Li Luo | 2013 | Acta Biochimica et Biophysica Sinica2013，45，10： | 3 |
| 12 | PrP mutants with different numbers of octarepeat sequences are more susceptible to the oxidative stress显示文摘One of the physiological functions of cellular prion protein(PrP C )is believed to work as a cellular resistance to oxidative stress,in which the octarepeats region within PrP plays an important role.However,the detailed mechanism is less clear.In this study,the expressing plasmids of wild-type PrP (PrP-PG5)and various PrP mutants containing 0(PrP-PG0),9(PrP-PG9)and 12(PrP-PG12)octarepeats were generated and PrP proteins were expressed both in E.coli and in mammalian cells.Protein aggregation and formation of carbonyl groups were clearly seen in the recombinant PrPs expressed from E.coli after treatment of H2O2.MTT and trypan blue staining assays revealed that the cells expressing the mutated PrPs within octarepeats are less viable than the cells expressing wild-type PrP.Statistically significant high levels of intracellular free radicals and low levels of glutathione peroxidase were observed in the cells transfected with plasmids containing deleted or inserted octarepeats.Remarkably more productions of carbonyl groups were detected in the cells expressing PrPs with deleted and inserted octarepeats after exposing to H2O2.Furthermore,cells expressing wild-type PrP showed stronger resistant activity to the challenge of H2O2 at certain extent than the mutated PrPs and mock. These data provided the evidences that the octarepeats number within PrP is critical for maintaining its activity of antioxidation.Loss of its protective function against oxidative stress may be one of the possible pathways for the mutated PrPs to involve in the pathogenesis of familial Creutzfeldt-Jacob diseases. | AN Run1 ,2,DONG ChenFang 2,LEI YanJun 1,2,HAN Lu 2,LI Ping 2,CHEN JianMing 2,WANG GuiRong 2, SHI Qi 2 ,GAO Chen 2 ,JIANG HuiYing 2 ,ZHOU Wei 2 ,HAN Jun 2 ,CHU YongLie 1 ,DONG XiaoPing 2 1School of Medicine,Xi’an JiaoTong University,Xi’an 710061,China 2State Key Laboratory for Infectious Disease Prevention and Control,National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention,YingXin Rd 100,Beijing 100052,China | 2008 | Science China(Life Sciences)2008，51，7： | 3 |
| 13 | Active Control Law Design for Flutter/LCO Suppression Based on Reduced Order Model Method显示文摘Active stability augmentation system is an attractive and promising technology to suppress flutter and limit cycle oscillation(LCO).In order to design a good active control law,the control plant model with low order and high accuracy must be provided,which is one of the most important key points.The traditional model is based on low fidelity aerodynamics model such as panel method,which is unsuitable for transonic flight regime.The physics-based high fidelity tools,reduced order model(ROM) and CFD/CSD coupled aeroservoelastic solver are used to design the active control law.The Volterra/ROM is applied to constructing the low order state space model for the nonlinear unsteady aerodynamics and static output feedback method is used to active control law design.The detail of the new method is demonstrated by the Goland+ wing/store system.The simulation results show that the effectiveness of the designed active augmentation system,which can suppress the flutter and LCO successfully. | Chen Gang Li Yueming Yan Guirong | 2010 | Chinese Journal of Aeronautics2010，23，6： | 3 |
| 14 | Photoluminescence Properties of Porous Silicon Based on FZ(H) Si Wafer显示文摘The photoluminescence (PL) properties of porous silicon (PS) have been studied based on n-type single- crystal (111) silicon wafers (80-90Ω .cm in the resistivity). The porous silicon layers (PSL) were created by anodizing the wafers with a denuded zone of 20-40 μm formed by neutron transmutation doping (NTD) and thermal treatment at 940℃ for 4 h and then 700℃ for 2 h, two-step heating of the floating-zone silicon (FZ Si) grown in a hydrogen (H2) ambience. By surface modification with stannic chloride or amine immersion and rapid thermal oxidation (RTO), the PL peak position from the PS can be qualitatively controlled factitiously. The as-prepared PS shows an orange-yellow luminescence, while the modified samples emit red, green and blue luminescence. Mechanisms for the different colors of the PL are discussed. Fourier transform infrared (FTIR) is carried out to analyze the differences in the structural configuration of the PS samples. | Yuejiao He, Huaixiang Li, Chenghua Guo, Guirong Liu, Yansheng Chen, Shuzhen Duan (Institute of Semiconductors, Shandong Normal University, Jinan 250014, China Metallurgy School, University of Science and Technology Beijing, Beijing 100083, China) | 2001 | Rare Metals2001，20，1： | 2 |
| 15 | Analysis of the Influencing Factors of Changes in Foxtail Millet Planting Area in Hebei Province显示文摘Since reform and open to the outside world,foxtail millet planting area in Hebei Province has constantly reduced,and its planting region has changed from the whole province into some regions,with obvious changes. In this paper,by using qualitative and quantitative approaches like chart analysis,summarizing,Delphi method and osculating value model,the influencing factors of changes in millet growing region in Hebei Province were studied. The results showed that the changes of millet planting area were closely related to many factors,such as little investment in scientific research,weak policy support,a single consumer product demand,the rapid development of other staple crops, labor migration,relatively low comparative effectiveness and physiological characteristics of the millet itself. Then some suggestions were put forward,such as increasing research support,strengthening scientific research strength,researching and developing deeply processed products, expanding consumer groups,improving millet policy support,providing subsidies for planting the improved varieties,researching and developing various types of machinery,and increasing millet production technology training. | Meng LIU Yu ZHAO Fei LIU Shunguo LI Guirong WANG Xinshi ZHANG | 2013 | Asian Agricultural Research2013，5，3： | 2 |
| 16 | A Clicked Tetrathiafulvalene-oxyquinoline Dyad as an Optical and Electrochemical Zn2+ Probe显示文摘一篇小说点按 tetrathiafulvalene 衍生物 3 生二个 8-oxyquinoline 组通过光、电气化学的变化为 Zn2+ 的选择察觉被综合。Zn2+ 和 Cd2+ 的增加在荧光紧张导致了一个重要变化,它对从 oxyquinoline 和 1,2,3-triazole 戒指的提高 chelation 的荧光效果可归因。3 的电气化学的潜力测试的另外的金属阳离子相对那些向更积极的价值面对 Zn2+ 被转移。 | Zhao,Bangtun Liu,Lianwei Li,Xiaochuan Qu,Guirong | 2012 | Chinese Journal of Chemistry2012，30，2： | 2 |
| 17 | Cytocompatibility of High Nitrogen Nickel-Free Stainless Steel for Orthopedic Implants显示文摘Cytocompatibility of high nitrogen nickel-free stainless steel(HNS) with different nitrogen content was evaluated and compared with a conventional austenitic stainless steel 317L.The MTT assay(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) was performed on MG63 osteoblasts to assess the cytotoxicity.The expression of selected marker typical of differentiated osteoblasts,such as alkaline phosphatase activity(AKP),was also monitored in MG63 cells cultured on the tested materials.As a result,HNS had higher cell growth than 317L;meanwhile the cytocompatibility was increased with increasing nitrogen content.Furthermore,HNS enhanced osteoblasts differentiation,as confirmed by AKP activity.Overall these facts indicated that HNS had higher cytocompatibility than 317L and the nitrogen content contributed to the higher cytocompatibility of HNS.The influence of nitrogen on surface energy further explained the cytocompatibility of HNS. | Tianchi Ma Peng Wan Yuyan Cui Guirong Zhang Jiqiang Li Jihui Liu Yibin Ren Ke Yangg Li Lu | 2012 | Journal of Materials Science & Technology2012，28，7： | 2 |
| 18 | Sinorhizobium meliloti lsrB is involved in alfalfa root nodule development and nitrogen-fixing bacteroid differentiation显示文摘Rhizobia interact with host legumes to induce the formation of nitrogen-fixing nodules,which is very important in agriculture and ecology.The development of nitrogen-fixing nodules is stringently regulated by host plants and rhizobial symbionts.In our previous work,a new Sinorhizobium meliloti LysR regulator gene(lsrB)was identified to be essential for alfalfa nodulation.However,how this gene is involved in alfalfa nodulation was not yet understood.Here,we found that this gene was associated with prevention of premature nodule senescence and abortive bacteroid formation.Heterogeneous deficient alfalfa root nodules were induced by the in-frame deletion mutant of lsrB(lsrB1-2),which was similar to the plasmid-insertion mutant,lsrB1.Irregular senescence zones earlier appeared in these nodules where bacteroid differentiation was blocked at different stages from microscopy observations.Interestingly,oxidative bursts were observed in these nodules by DAB staining.The decreased expression of lipopolysaccharide core genes(lpsCDE)was correspondingly determined in these nodules.S.meliloti lipopolysaccharide is required for suppression of oxidative bursts or host cell defense.These findings demonstrate that the S.meliloti lsrB gene is involved in alfalfa root nodule development and bacteroid differentiation by suppressing oxidative bursts or defense responses in host cells. | TANG GuiRong LU DaWei WANG Dong LUO Li | 2013 | Chinese Science Bulletin2013，58，33： | 2 |
| 19 | Structural and enhanced memory activity studies of extracts from Panax ginseng root显示文摘 | Ying Wang Ruizhi Jiang Guirong Li Yinghong Chen Haoming Luo Yang Gao Qipin Gao | 2009 | Food Chemistry2009，，3： | 1 |
| 20 | Analysis of plates and shells using an edge-based smoothed finite ele- ment method显示文摘 | CUI Xiangyang LIU Guirong LI Guangyao | 2010 | Comput Mech2010，45，： | 1 |
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