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| 1 | Effect of electric acupoint stimulation on gastrointestinal hormones and motility among geriatric postoperative patients with gastrointestinal tumors显示文摘OBJECTIVE:To evaluate the effects of electric acupoint stimulation on gastrointestinal hormones and motility among geriatric postoperative patients with gastrointestinal tumors,and to explore an efficient and noninvasive method for postoperative recovery of bowel functions.METHODS:Forty patients were randomly and evenly assigned into a regular nursing care group(RNC) and an acupoint electric stimulation group(AES).Patients in the RNC group received regular nursing care and patients in the AES group received regular nursing care plus electric stimulation of acupoints.The serum levels of gastrin(GAS),motilin(MOT),and cholecystokinin(CCK),and an electrogastrogram(EGG) of all the patients were evaluated on the first,third,and fifth day after surgery.The time to first flatus after surgery and the number of patients with side effects such as abdominal pain,abdominal distention,and diarrhea were recorded.RESULTS:There were significant differences between the two groups in GAS,MOT,EGG,time to first flatus,abdominal pain,abdominal distention,and diarrhea(P < 0.05).CONCLUSION:Electric stimulation on acupoints could increase levels of GAS and MOT,promote the recovery of gastrointestinal functions,and decrease complications among postoperative senile patients with gastrointestinal tumors. | Hou Lili Xu Lei Shi Yan Gu Fen | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 15 |
| 2 | The role of autophagic and lysosomal pathways in ischemic brain injury显示文摘Autophagy is involved in neural cell death after cerebral ischemia. Our previous studies showed that rapamycin-induced autophagy decreased the rate of apoptosis, but the rate of apoptosis was in-creased after the autophagy inhibitor, 3-methyladenine, was used. In this study, a suture-occluded method was performed to generate a rat model of brain ischemia. Under a transmission electron microscope, autophagic bodies and autophagy lysosomes were markedly accumulated in neurons at 4 hours post brain ischemic injury, with their numbers gradually reducing over time. Western blotting demonstrated that protein levels of light chain 3-II and cathepsin B were significantly in-creased within 4 hours of ischemic injury, but these levels were not persistently upregulated over time. Confocal microscopy showed that autophagy was mainly found in neurons with positive light chain 3 signal. Injection of rapamycin via tail vein promoted the occurrence of autophagy in rat brain tissue after cerebral ischemia and elevated light chain 3 and cathepsin B expression. However, in-jection of 3-methyladenine significantly diminished light chain 3-II and cathepsin B expression. Results verified that autophagic and lysosomal activity is increased in ischemic neurons. Abnormal components in cells can be eliminated through upregulating cell autophagy or inhibiting autophagy after ischemic brain injury, resulting in a dynamic balance of substances in cells. Moreover, drugs that interfere with autophagy may be potential therapies for the treatment of brain injury. | Zhaohua Gu Yinyi Sun Kangyong Liu Fen Wang Ting Zhang Qiang Li Liwei Shen Ling Zhou Liang Dong Nan Shi Qian Zhang Wei Zhang Meizhen Zhao Xiaojiang Sun | 2013 | Neural Regeneration Research2013，8，23： | 2 |
| 3 | Value of radiotherapy after radical surgery for esophageal carcinoma: a report of 495 patients显示文摘 | Ze Fen Xiao Zong Yi Yang Jun Liang Yan Jun Miao Mei Wang Wei Bo Yin Xian Zhi Gu De Chao Zhang Ru Gang Zhang Liang Jun Wang | 2003 | The Annals of Thoracic Surgery2003，，2： | 2 |
| 4 | Value of radiotherapy after radical surgery for esophageal carcinoma: a report of 495 patients显示文摘 | Ze Fen Xiao Zong Yi Yang Jun Liang Yan Jun Miao Mei Wang Wei Bo Yin Xian Zhi Gu De Chao Zhang Ru Gang Zhang Liang Jun Wang | 2003 | The Annals of Thoracic Surgery2003，，2： | 1 |
| 5 | Isolation and characterization of an acidic polysaccharide from Mesoua Blumes gum 显示文摘 | FEN T GU Z B JIN Z Y | 2008 | Carbohydrate Polymers2008，71，2： | 1 |
| 6 | The preparation ofhigh-strength and micropore lightweight bauxite aggregate by in-situpolymerization and decomposition 显示文摘 | Fang Yineng Gu Huazhi Fen Yunsheng | 2011 | Advanced Materials Research2011，，： | 1 |
| 7 | Synthesis and photoluminescence characteristics of Dy3+ -doped ZnAl2O4 nanocrystals via a combustion process显示文摘 | Shu Fen Wang Feng Gu | 2005 | Journal of Alloys and Compounds2005，394，： | 1 |
| 8 | Photoluminescence characteristics of Pb 2+ ion in sol–gel derived ZnTiO 3 nanocrystals显示文摘 | Shu Fen Wang Meng Kai Lü Feng Gu Chun Feng Song Dong Xu Duo Rong Yuan Guang Jun Zhou Yong Xin Qi | 2002 | Inorganic Chemistry Communications2002，，： | 1 |
| 9 | Preparation and characterization of sol–gel derived ZnTiO 3 nanocrystals显示文摘 | Shu Fen Wang Feng Gu Meng Kai Lü Chun Feng Song Su Wen Liu Dong Xu Duo Rong Yuan | 2003 | Materials Research Bulletin2003，，8： | 1 |
| 10 | Photoluminescence of sol–gel derived ZnTiO 3 :Ni 2+ nanocrystals显示文摘 | Shu Fen Wang Feng Gu Meng Kai Lü Chun Feng Song Dong Xu Duo Rong Yuan Su Wen Liu | 2003 | Chemical Physics Letters2003，，： | 1 |
| 11 | Green liquor pretreatment for improving enzymatic hydrolysis of corn stover显示文摘 | GU Fen YANG Lin-feng JIN Yong-cang | 2012 | Bioresource Technology2012，，124： | 1 |
| 12 | Photoluminescence characteristics of ZnTiO 3 : Bi 3+ nanocrystals显示文摘 | Shu Fen Wang Feng Gu Meng Kai Lü Wen Guo Zou Su Wen Liu Dong Xu Duo Rong Yuan Guang Jun Zhou | 2004 | Journal of Physics and Chemistry of Solids2004，，： | 1 |
| 13 | Preparation and characterization of sol-gel derived ZnTiO3 nanocrystals 显示文摘 | SHU FEN WANG FENG GU MENG KAI LU | 2003 | Materials Research Bulletin2003，38，： | 1 |
| 14 | Value of radiotherapy after radical surgery for esophageal carcinoma: a report of 495 patients显示文摘 | Ze Fen Xiao Zong Yi Yang Jun Liang Yan Jun Miao Mei Wang Wei Bo Yin Xian Zhi Gu De Chao Zhang Ru Gang Zhang Liang Jun Wang | 2003 | The Annals of Thoracic Surgery2003，，2： | 1 |
| 15 | POTASSIUM FLUORIDE ON ALUMINA CATALYZED ALDOL CONDENSATION OF INDENE AND ACETOPHENONE显示文摘POTASSIUM FLUORIDE ON ALUMINA CATALYZED ALDOL CONDENSATION OF INDENE AND ACETOPHENONEPOTASSIUMFLUORIDEONALUMINACATALYZEDALDOL... | Weng Xing LU Chao Guo YAN Hui Fen GU(Dept. of Chem., Teachers college of Yangzhou University. Yangzhou. 225002) | 1994 | Chinese Chemical Letters1994，5，9： | 0 |
| 16 | Analysis of the Clinical Interventions for Falls in Elderly Patients in the Community From 2002 To 2022:A Bibliometric Analysis显示文摘Objective:To analyze and provide a comprehensive overview of the knowledge structure and research hotspots of clinical interventions for falls in elderly patients in the community.Methods:The search for publications related to clinical interventions for falls in elderly patients in the community from 2002 to 2022 was conducted on the Web of Science Core Collection(WoSCC)database.VOSviewers,CiteSpace,and the R package“bibliometrix”were used to conduct this bibliometric analysis.Results:2091 articles from 70 countries,primarily the United States and Australia,were included.The number of publications related to clinical interventions for falls in elderly patients is increasing yearly.The main research institutions in this field were the University of Sydney,Harvard University,and the University of California.BioMed Central(BMC)Geriatrics was the most popular journal in this field and Journals of the American Geriatrics Society was the most co-cited journal.These publications came from 8984 authors among which author Lord SR had published the most papers and author Tinetti Me had the most co-citations.The main keywords in this research field were“balance,”“exercise,”and“risk factor.”Conclusion:This was the first bibliometric study that comprehensively summarized the research hot spots and development of clinical interventions for falls in elderly patients in the community.This paper aims to provide a reference for scholars and researchers in this particular field. | Xiaoxiao Zhu Yue Zhang Fen Gu | 2024 | Journal of Clinical and Nursing Research2024，8，3： | 0 |
| 17 | Fatigue correlates with sleep disturbances in Parkinson disease显示文摘Background: Many Parkinson disease (PD) patients complain about chronic fatigue and sleep disturbances during the night. The objective of this study is to determine the relationship between fatigue and sleep disturbances by using polysomnography (PSG) in PD patients.Methods: Two hundred and thirty-two PD patients (152 with mild fatigue and 80 with severe fatigue) were recruited in this study. Demographic information and clinical symptoms were collected. Fatigue severity scale (FSS) was applied to evaluate the severity of fatigue, and PSG was conducted in all PD patients. FSS ≥4 was defined as severe fatigue, and FSS <4 was defined as mild fatigue. Multivariate logistic regression and linear regression models were used to investigate the associations between fatigue and sleep disturbances.Results: Patients with severe fatigue tended to have a longer duration of disease, higher Unified Parkinson Disease Rating Scale score, more advanced Hoehn and Yahr stage, higher daily levodopa equivalent dose, worse depression, anxiety, and higher daytime sleepiness score. In addition, they had lower percentage of rapid eye movement (REM) sleep (P = 0.009) and were more likely to have REM sleep behavior disorder (RBD) (P = 0.018). Multivariate logistic regression analyses found that the presence of RBD and proportion of REM sleep were the independent predictors for fatigue. After the adjustment of age, sex, duration, body mass index, severity of disease, scores of Hamilton Rating Scale for Depression, Hamilton Anxiety Rating Scale, and other sleep disorders, proportion of REM sleep and degree of REM sleep without atonia in patients with PD were still associated with FSS score.Conclusion: Considering the association between fatigue, RBD, and the altered sleep architecture, fatigue is a special subtype in PD and more studies should be focused on this debilitating symptom. | Xiang-Yang Cao Jin-Ru Zhang Yun Shen Cheng-Jie Mao Yu-Bing Shen Yu-Lan Cao Han-Ying Gu Fen Wang Chun-Feng Liu | 2021 | Chinese Medical Journal2021，，6： | 0 |
| 18 | Diagnostic Efficacy of^(18)F-FDG PET/CT in Detecting Bone Marrow Infiltration in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma显示文摘Objective Diffuse large B-cell lymphoma(DLBCL)is often associated with bone marrow infiltration,and 2-deoxy-2-(18F)fluorodeoxyglucose positron emission tomography/computed tomography(^(18)F-FDG PET/CT)has potential diagnostic significance for bone marrow infiltration in DLBCL.Methods A total of 102 patients diagnosed with DLBCL between September 2019 and August 2022 were included.Bone marrow biopsy and^(18)F-FDG PET/CT examinations were performed at the time of initial diagnosis.Kappa tests were used to evaluate the agreement of^(18)F-FDG PET/CT with the gold standard,and the imaging features of DLBCL bone marrow infiltration on PET/CT were described.Results The total detection rate of bone marrow infiltration was not significantly different between PET/CT and primary bone marrow biopsy(P=0.302)or between the two bone marrow biopsies(P=0.826).The sensitivity,specificity,and Youden index of PET/CT for the diagnosis of DLBCL bone marrow infiltration were 0.923(95%CI,0.759-0.979),0.934(95%CI,0.855-0.972),and 0.857,respectively.Conclusion^(18)F-FDG PET/CT has a comparable efficiency in the diagnosis of DLBCL bone marrow infiltration.PET/CT-guided bone marrow biopsy can reduce the misdiagnosis of DLBCL bone marrow infiltration. | GUO Bo QIN Ran GU Zhen Yang LI Yan Fen GAO Lei HUANG Wen Rong | 2023 | Biomedical and Environmental Sciences2023，36，6： | 0 |
| 19 | Rapid assembly of 1,3-indanedione-based spirocyclic tetrahydroquinolines for inducing human lung cancer cell apoptosis显示文摘The rapid collection of a library of biologically relevant molecules is essential in new drug discovery.Here we show a variety of bioactive 1,3-indanedione-based spirocyclic tetrahydroquinolines that have been concisely and efficiently constructed under the guidance of biology-oriented synthesis(BIOS).Using Pd(PPh_(3))_(4) as a catalyst,various 2-arylidene-1,3-indanediones can react with vinyl benzoxazinanones under the mild condition to afford a new class of spirocyclic tetrahydroquinolines in moderate to excellent yields(45%-99%)with high stereocontrol(>95:5 diastereoselectivity).Their structures were unambiguously confirmed by X-ray single crystal analysis.The biological evaluation revealed that two of the 1,3-indanedione-based spirocyclic tetrahydroquinolines show remarkable apoptosis-inducing activities over A549 human lung cancer cells,exceeding that of cisplatin.The antitur activities were triggered by reactive oxygen species,commonly overproduced in cancer cells.The clinical demand for antitumor chemotherapy for lung cancer has encouraged an all-out search for analogues with lower toxcity,improved therapeutic index and increased activity. | Fen Tan Luojia Chen Yuncong Yuan Xiaoyu He Yiwen Su Shuqiang Cao Conghua Xie Meijia Gu Youquan Zou | 2022 | Green Synthesis and Catalysis2022，3，4： | 0 |
| 20 | Low Temperature Heat Capacity of Zn Substituted Cobalt Ferrite Nanosphere:The Relation between Magnetic Properties and Microstructure显示文摘Co_((1-x))ZnxFe_(2)O_(4)nanospheres(x=0,0.5,0.8)with a unidirectional cubic spinel structure were prepared by a solvothermal method.By using a range of theoretical and empirical models,the experimental heat capacity values were fitted as a function of temperature over a suitable temperature range to explain the possible relationship between the magnetic properties and microstructure of the nanospheres.As a result,at a low temperature(T<10 K),the parameter Bfswdecreases with increasing Zn concentration,implying that the exchange interaction between A and B sites decreases.At a relatively high temperature(T>50 K),the Debye temperature decreases with increasing Zn concentration,which is due to the weakening of the interatomic bonding force after the addition of non-magnetic materials to the Co Fe_(2)O_(4)spinel ferrite. | YUAN Meng GU Xiaojie FU Jie WANG Shaoxu SHI Quan TAN Zhicheng XU Fen | 2023 | Journal of Wuhan University of Technology(Materials Science)2023，38，5： | 0 |
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