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您的检索式：作者名="Gregory J Stoddard"
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| 1 | Determinants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke显示文摘Introduction: Increased blood pressure variability (BPV) is detrimental after acute ischaemic stroke, but the interaction between BPV and neuroimaging factors that directly influence stroke outcome has not been explored. Methods: We retrospectively reviewed inpatients from 2007 to 2014 with acute anterior circulation ischaemic stroke, CT perfusion and angiography at hospital admission, and a modified Rankin Scale (MRS) 30- 365 days after stroke onset. BPV indices included SD, coefficient of variation and successive variation of the systolic blood pressure between 0 and 120 hours after admission. Ordinal logistic regression models were fitted to MRS with predictor variables of BPV indices. Models were further stratified by CT perfusion volumetric measurements, proximal vessel occlusion and collateral score. Results: 110 patients met the inclusion criteria. The likelihood of a 1-point rise in the MRS increased with every 10 mm Hg increase in BPV (OR for the 3 BPV indices ranged from 2.27 to 5.54), which was more pronounced in patients with larger ischaemic core volumes (OR 8.37 to 18.0) and larger hypoperfused volumes (OR 6.02 to 15.4). This association also held true for patients with larger mismatch volume, proximal vessel occlusion and good collateral vessels. Conclusions: These results indicate that increased BPV is associated with worse neurological outcome after stroke, particularly in patients with a large lesion core volume, concurrent viable ischaemic penumbra, proximal vessel occlusion and good collaterals. This subset of patients, who are often not candidates for or fail acute stroke therapies such as intravenous tissue plasminogen activator or endovascular thrombectomy, may benefit from interventions aimed at reducing BPV. | Adam de Havenon Alicia Bennett Gregory J Stoddard Gordon Smith Lee Chung Steve O’Donnell J Scott McNally David Tirschwell Jennifer J Majersik | 2017 | Stroke & Vascular Neurology2017，2，1： | 6 |
| 2 | Low plasma arginine concentrations in children with cerebral malaria and decreased nitric oxide production显示文摘 | Bert K Lopansri Nicholas M Anstey J Brice Weinberg Gregory J Stoddard Maurine R Hobbs Marc C Levesque Esther D Mwaikambo Donald L Granger | 2003 | The Lancet2003，，9358： | 1 |
| 3 | Adipocyte iron regulates leptin and food intake显示文摘 | Gao Yan Li Zhonggang Gabrielsen J Scott Simcox Judith A Lee Soh-hyun Jones Deborah Cooksey Bob Stoddard Gregory Cefalu William T McClain Donald A | 2015 | Journal of Clinical Investigation2015，，9： | 1 |
| 4 | A Prospective Evaluation :The Infusion Nurse and Patient Complication Rates of Peripheral-Short Catheters显示文摘 | Sandra Solomon Palefski Gregory J Stoddard | 2001 | J Intraven Nurs2001，24，2： | 1 |
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