2篇
您的检索式：作者名="Giulio Riva"
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| 1 | Ampulla of Vater carcinoma: Molecular landscape and clinical implications显示文摘Ampulla of Vater is a peculiar anatomical structure, characterized by the crossroad of three distinct epithelia: Intestinal, ductal pancreatic and biliary. Adenocarcinomas arising in this area represent an opportunity to understand the comparative biology of all periampullary malignancies. These neoplasms can exhibit intestinal, pancreaticobiliary or mixed features, whereas the subclassification based on morphology and immunohistochemical features failed in demonstrating a robust prognostic reliability. In the last few years, the molecular landscape of this tumor entity has been uncovered, identifying alterations that may serve as prognostic and predictive biomarkers. In this review, the histological and genetic characteristics of ampullary carcinomas are discussed, taking into account the main clinical and therapeutic implications related to this tumor type as well. | Antonio Pea Giulio Riva Riccardo Bernasconi Elisabetta Sereni Rita Teresa Lawlor Aldo Scarpa Claudio Luchini | 2018 | World Journal of Gastrointestinal Oncology2018，10，11： | 4 |
| 2 | Histo-molecular oncogenesis of pancreatic cancer:From precancerous lesions to invasive ductal adenocarcinoma显示文摘Pancreatic cancer is a lethal malignancy,whose precursor lesions are pancreatic intraepithelial neoplasm,intraductal papillary mucinous neoplasm,intraductal tubulopapillary neoplasm,and mucinous cystic neoplasm.To better understand the biology of pancreatic cancer,it is fundamental to know its precursors and to study the mechanisms of carcinogenesis.Each of these precursors displays peculiar histological features,as well as specific molecular alterations.Starting from such pre-invasive lesions,this review aims at summarizing the most important aspects of carcinogenesis of pancreatic cancer,with a specific focus on the recent advances and the future perspectives of the research on this lethal tumor type. | Giulio Riva Antonio Pea Camilla Pilati Giulia Fiadone Rita Teresa Lawlor Aldo Scarpa Claudio Luchini | 2018 | World Journal of Gastrointestinal Oncology2018，10，10： | 0 |
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