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| 1 | Portal vein thrombosis:Insight into physiopathology,diagnosis,and treatment显示文摘Portal vein thrombosis (PVT) is a relatively common complication in patients with liver cirrhosis, but might also occur in absence of an overt liver disease. Several causes, either local or systemic, might play an important role in PVT pathogenesis. Frequently, more than one risk factor could be identified; however, occasionally no single factor is discernable. Clinical examination, laboratory investigations, and imaging are helpful to provide a quick diagnosis, as prompt treatment might greatly affect a patient's outcome. In this review, we analyze the physiopathological mechanisms of PVT development, together with the hemodynamic and functional alterations related to this condition. Moreover, we describe the principal factors most frequently involved in PVT development and the recent knowledge concerning diagnostic and therapeutic procedures. Finally, we analyze the implications of PVT in the setting of liver transplantation and its possible influence on patients' future prognoses. | Francesca R Ponziani Maria A Zocco Chiara Campanale Emanuele Rinninella Annalisa Tortora Luca Di Maurizio Giuseppe Bombardieri Raimondo De Cristofaro Anna M De Gaetano Raffaele Landolfi Antonio Gasbarrini | 2010 | World Journal of Gastroenterology2010,16,2: | 75 |
| 2 | Intestinal permeability after Mediterranean diet and low-fat diet in non-alcoholic fatty liver disease显示文摘BACKGROUND In non-alcoholic fatty liver disease(NAFLD), a high-fat or high-fructose diet increases intestinal permeability and promotes derangement of the gut-liver axis.We hypothesize that, diet could be able to modulate intestinal permeability in patients with NAFLD.AIM To detect diet-induced modification of intestinal permeability in patients with NAFLD undergoing a Mediterranean diet or a low-fat diet.METHODS The current study was a dietary intervention for non-diabetic, patients with biopsy-verified NAFLD and increased transaminases. A crossover design was employed: participants underwent 16 weeks of Mediterranean diet, 16 wk of free wash-out, and 16 weeks of low-fat diet. Both diets were hypocaloric and no consumption of supplements was allowed. All patients were followed bimonthly by a dietitian. Evaluations of clinical and metabolic parameters were completed at baseline and at the end of each dietary period. Intestinal permeability was assessed by chromium-51 ethylene diamine tetraacetate excretion testing(51 CrEDTA).RESULTS Twenty Caucasian patients, 90% male, median age 43 years, body mass index(BMI) 30.9, with biopsy-verified NAFLD were enrolled. At the end of 16 weeks of a Mediterranean diet, a significant reduction in mean body weight(-5.3 ± 4.1 kg,P = 0.003), mean waist circumference(-7.9 ± 4.9 cm, P = 0.001), and mean transaminase levels [alanine aminotransferase(ALT)-28.3 ± 11.9 IU/L, P =0.0001; aspartate aminotransferase(AST)-6.4 ± 56.3 IU/L, P = 0.01] were observed. These benefits were maintained after 16 wk of wash-out and also after16 wk of low-fat diet, without further improvements. Fourteen of the 20 patients had intestinal permeability alteration at baseline(mean percentage retention of51 Cr-EDTA = 5.4%), but no significant changes in intestinal permeability were observed at the end of the 16 wk of the Mediterranean diet or 16 wk of the low-fat diet.CONCLUSION Mediterranean diet is an effective strategy for treating overweight, visceral obesity and serum transaminase in patients with NAFLD. If the Mediterranean diet can improve intestinal permeability in patients with NAFLD, it deserves further investigation. | Marco Biolato Fiorella Manca Giuseppe Marrone Consuelo Cefalo Simona Racco Giacinto A Miggiano Venanzio Valenza Antonio Gasbarrini Luca Miele Antonio Grieco | 2019 | World Journal of Gastroenterology2019,25,4: | 4 |
| 3 | Regression of au-toimmune thrombocytopenia after eradication of Helicobacter pylori显示文摘 | Gasbarrini A Franceschi F Tartaglione R | 1998 | Lancet1998,352,9131: | 1 |
| 4 | Association of helicobacter pylori infection with raynaud phenomenon显示文摘 | Gasbarrini A Serricchio M Tondi P | 1996 | Lancet1996,348,: | 1 |
| 5 | The mode of transmission of Helicobacter pylori infenction显示文摘 | Turoi A Gasbarrini Fedell G | 1997 | RECEN TI proy MED1997,88,5: | 1 |
| 6 | Regression of autoimmune thrombocytopenia after of helicobacter pylori 显示文摘 | Gasbarrini A Pranceschi P Tartaglione R | 1998 | Lancet1998,,: | 1 |
| 7 | Helicobactor Pylori and Raynaud phenomenon显示文摘 | Massari M Sericchio M | 1997 | Gastroenterol Int1997,10,1: | 1 |
| 8 | Regression of autoimmune thrombocytopenia after eradication of helicobacter pylori显示文摘 | Gasbarrini A Franceschi F Tartaglione R | 1998 | Lancet1998,352,9131: | 1 |
| 9 | Helicobaetor Pylori and primary headache 显示文摘 | De Luea A Fiore G | 1997 | Gastroenterol Int1997,10,1: | 1 |
| 10 | Intraepiphyseal resection of the proximal tibia and its impact on lewer limb growth显示文摘 | Manfrini M Gasbarrini A Malaguti C | 1999 | Clin Orthop1999,358,: | 1 |
| 11 | Efficacy of different Helicobacter pylori eradication regimens in patients affected by insulin - dependent diabetes mellitus 显示文摘 | Gasbarrini A Ojetti V Pitocco D | 2000 | Scand J Gastroenterol2000,35,: | 1 |
| 12 | Regression of autoimmune thrombocytopenia after eradication of helicobacter pylori显示文摘 | Gasbarrini A Franceschi F Tartaglione R | 1998 | Lancet1998,352,9131: | 1 |
| 13 | Small intestinal bacterial overgrowth : diagnosis and treatment 显示文摘 | Gasbarrini A Lauritano EC Gabrielli M | 2007 | Dig Dis2007,25,3: | 1 |
| 14 | Extradigestive manifestations of Helicobacter pylori gastric infection显示文摘 | Gasbarrini A Franceschi F Armuzzi A | 1999 | Gut1999,,: | 1 |
| 15 | New insights into the pathophysiology of I BS:intestinal micro flora,gas production and gut motility 显示文摘 | GASBARRINI A LAURITANO EC GARCOVICH M | 2008 | Eur Rev Med Pharmaeol Sci2008,121,: | 1 |
| 16 | Cross-reactivity of an- ti-CagA antibodies with vascular wall antigens 显示文摘 | Franceschi F Sepulveda AR Gasbarrini A | 2002 | Circulation2002,106,: | 1 |
| 17 | Regression of autoimmune thro mbocytopenia after eradication of Helicobacter pylori显示文摘 | Gasbarrini A Franceschi F Tartglione R | 1998 | Lancet1998,352,9131: | 1 |
| 18 | Insulin -dependent diabetes mellitus affects eradication rate of Helicobacter pylori infection 显示文摘 | Gasbarrini A Ojetti V Pitocco D | 1999 | Eur J Gastroenterol Hepatol1999,11,: | 1 |
| 19 | Autcimmune diseases and Helicobater pylori infefction 显示文摘 | Gasbarrini A franceshi F | 1999 | Iomed Phannacother1999,53,56: | 1 |
| 20 | Cross- reactivity of anti- CagA antibodies with vascular wall antigens: possible pathogenic link between Helicobacter pylori infection athercsclerosis 显示文摘 | FRANCESCHI F SEPULVEDA A R GASBARRINI A | 2002 | Circulation2002,106,4: | 1 |