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| 1 | Diabetic Retinopathy显示文摘 | Thomas W Gardner David A Antonetti Alistair J Barber Kathryn F LaNoue Steven W Levison | 2002 | Survey of Ophthalmology2002，，： | 2 |
| 2 | SOFC technology development at Rolls-Royce显示文摘 | Gardner F J Day M J Brandon N P | 2000 | J Power Sources2000，86，： | 2 |
| 3 | Increased presence of effector lymphocytes during Helicobacter hepaticus-induced colitis显示文摘AIM:To identify and characterize drosophila mothers against decapentaplegic(SMAD)3-dependent changes in immune cell populations following infection with Helicobacter hepaticus(H.hepaticus).METHODS:SMAD3 -/-(n=19)and colitis-resistant SMAD3+/-(n=24)mice(8-10 wk of age)were in-fected with H.hepaticus and changes in immune cell populations[T lymphocytes,natural killer(NK)cells,T regulatory cells]were measured in the spleen and mesenteric lymph nodes(MsLNs)at 0 d,3 d,7 d and 28 d post-infection using flow cytometry.Genotypedependent changes in T lymphocytes and granzyme B+ cells were also assessed after 28 d in proximal colon tissue using immunohistochemistry.RESULTS:As previously observed,SMAD3 -/-,but not SMAD3+/-mice,developed colitis,peaking at 4 wk post-infection.No significant changes in T cell subsets were observed in the spleen or in the MsLNs between genotypes at any time point.However,CD4+and CD8+/ CD62Llo cells,an effector T lymphocyte population,as well as NK cells(NKp46/DX5+)were significantly higher in the MsLNs of SMAD3-/-mice at 7 d and 28 d post-infection.In the colon,a higher number of CD3+cells were present in SMAD3-/-compared to SMAD3+/-mice at baseline,which did not significantly change during infection.However,the number of granzyme B+cells,a marker of cytolytic lymphocytes,significantly increased in SMAD3-/-mice 28 d post-infection compared to both SMAD3+/-mice and to baseline values.This was consistent with more severe colitis development in these animals.CONCLUSION:Data suggest that defects in SMAD3 signaling increase susceptibility to H.hepaticus-induced colitis through aberrant activation and/or dysregulation of effector lymphocytes. | Sarah J McCaskey Elizabeth A Rondini Jonathan F Clinthorne Ingeborg M Langohr Elizabeth M Gardner Jenifer I Fenton | 2012 | World Journal of Gastroenterology2012，18，13： | 2 |
| 4 | Organic nitrogen mineralization and substrate limitation of bacteria in Lake Michigan显示文摘 | Gardner W S Chandler J F Laird A G | 1989 | Limnol Oceanogr1989，34，2： | 1 |
| 5 | An examination of response-surface methodologies for uncertainty analysis in assessment models 显示文摘 | Downing D J Gardner R H Hoffman F O | 1985 | Technometrics1985，27，： | 1 |
| 6 | On the use of prompt gamma-ray neutron activation analysis for determining phase amounts in multiphase flow 显示文摘 | Wang J X Li F S Gardner R P | 2008 | Measurement Science and Technology2008，19，6： | 1 |
| 7 | N-terminal probrain natriuretic peptide:A new gold standard in predicting mortality in patients with advanced heart failure 显示文摘 | Gardner RS Ozalp F Murday A J | 2003 | Eur Heart J2003，24，19： | 1 |
| 8 | Characteristics and approximations of optimal force distributions in walking machines on rough terrain显示文摘 | GARDNER J F | 1991 | IEEE International Conference on Advanced Robotics1991，4，： | 1 |
| 9 | Prevention of tamoxifen induced endometrial polyps using a levonorgestrel releasing intrauterine system long-term follow-up of a randomised eontrol trial 显示文摘 | Gardner F J Konje JC Bell SC | 2009 | Gyneeol Oncol2009，114，3： | 1 |
| 10 | Polyhydroxy alkaloids:chromatographic analysis显示文摘 | Molyneux R J Gardner D R James L F | 2002 | Journal of Chromatography A2002，967，： | 1 |
| 11 | Improved classification of ancmias by MCV and PDW 显示文摘 | Bassman J D Wiliams L J Gardner F H | 1983 | Am J Clin path1983，80，3： | 1 |
| 12 | An experimental investigation of factors affecting elastic wave velocities in porous media显示文摘 | Wyllie M R J Gregory A R Gardner G H F | 1958 | Geophysics1958，23，： | 1 |
| 13 | Uni- pedicular balloon kyphoplasty for the treatment of osteo- porotic vertebral compression fractures:early results 显示文摘 | Papadopoulos EC Edobor-Osula F Gardner M J et a/ | 2008 | J Spinal Disord Tech2008，21，8： | 1 |
| 14 | Endometrial protection from tamoxifen stimulated changes by a levonorgestrel- releasing intrauterine system: a randomized controlled trial显示文摘 | Gardner F J Konje J C Abrams K R | 2000 | Lancet2000，356，9243： | 1 |
| 15 | An Experimental Investigation of Factors Affecting Elastic Wave Velocity Porous Media显示文摘 | Wyllie M R J Gardner G H F | 1958 | Geophysics1958，23，3： | 1 |
| 16 | Biofumigation:isothiocynates released from Brassica roots inhibit growth of the take-all fungus显示文摘 | Angus J F Gardner P A Kirkegaard J A | 1994 | Plant and Soil1994，162，： | 1 |
| 17 | Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John' swort, garlic oil Panax ginseng and ginkgo biloba 显示文摘 | GURLEY B J GARDNER S F HUBBARD M A | 2005 | Drugs Aging2005，22，6： | 1 |
| 18 | Unipe- dicular balloon kyphoplasty for the treatment of osteoporotic verte- bral compression fractures : early results显示文摘 | Papadopoulos EC Edobor-Osula F Gardner M J | 2008 | J Spinal Disord Tech2008，21，8： | 1 |
| 19 | Distribution and dynamics of nitrogen and microbial plankton in southern Lake Michigan during spring transition 1999-2000显示文摘 | Gardner W S Lavrentyev P J Cavaletto J F | | 0，，： | 1 |
| 20 | Eglciem computation of force distributions for walking machines on rough terrain显示文摘 | Gardner J F | 1992 | Robotica1992，10，5： | 1 |
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