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| 1 | Electro-acupuncture to prevent prolonged postoperative ileus:A randomized clinical trial显示文摘AIM:To examine whether acupuncture can prevent prolonged postoperative ileus(PPOI)after intraperitoneal surgery for colon cancer. METHODS:Ninety patients were recruited from the Fudan University Cancer Hospital,Shanghai,China. After surgery,patients were randomized to receive acupuncture(once daily,starting on postoperative day 1, for up to six consecutive days)or usual care.PPOI was defined as an inability to pass flatus or have a bowel movement by 96 h after surgery.The main outcomes were time to first flatus,time to first bowel movement, and electrogastroenterography.Secondary outcomes were quality of life(QOL)measures,including pain, nausea,insomnia,abdominal distension/fullness,and sense of well-being. RESULTS:No significant differences in PPOI on day 4 (P=0.71)or QOL measures were found between the groups.There were also no group differences when the data were analyzed by examining those whose PPOI had resolved by day 5(P=0.69)or day 6(P= 0.88).No adverse events related to acupuncture were reported. CONCLUSION:Acupuncture did not prevent PPOI andwas not useful for treating PPOI once it had developed in this population. | M Kay Garcia Joseph S Chiang Bob Thornton J Lynn Palmer Jennifer McQuade Lorenzo Cohen | 2010 | World Journal of Gastroenterology2010,16,1: | 27 |
| 2 | Tonoplast calcium sensors CBL2 and CBL3 control plant growth and ion homeostasis through regulating V-ATPase activity in Arabidopsis显示文摘对发展、环境的暗示的植物回答被钙经常调停(被多样的钙传感器播送的 Ca 2+) 信号。calcineurin 象 B 一样(CBL ) 蛋白质家庭代表通过和一组交往 CBL 蛋白质 kinases 的特定的相互作用译码钙信号的钙传感器。我们报导 Arabidopsis CBL2 和 CBL3 的功能的分析,对通过 N 终端指向 tonoplast 的 vacuolar 膜局部性的二个密切相关的 CBL 成员定序。当 cbl2 或 cbl3 单身者异种没从野类型显示出任何 phenotypic 差别时, cbl2 cbl3 两倍异种与叶尖端坏死,不发达的根,更短的 siliques 和更少种子被阻碍。这些缺点在 vha-a2 vha-a3 使人想起那些在 vacuolar H +-ATPase (V-ATPase ) 缺乏的两倍异种。确实, V-ATPase 活动在 cbl2 cbl3 被减少两倍变异的、连接 tonoplast CBL 类型钙传感器到 V-ATPase 的规定。而且, cbl2 cbl3 两倍异种在离子的忍耐和微量元素累积被损害,与在被显示了在离子区分工作的 V-ATPase 活动的缺点一致。我们的结果建议钙传感器 CBL2 和 CBL3 用作在钙发信号和 V-ATPase 之间的分子的连接,细胞内部的离子动态平衡的一个中央管理者。 | Ren-Jie Tang Hua Liu Yang Yang Lei Yang Xiao-Shu Gao Veder J Garcia Sheng Luan Hong-Xia Zhang | 2012 | Cell Research2012,22,12: | 26 |
| 3 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017,25,2: | 10 |
| 4 | 微波与感应加热对沥青混合料自愈特性影响研究显示文摘为了研究微波与感应加热对沥青混合料自愈特性的影响,采用裂-愈循环前后三点弯曲试验强度之比对愈合率进行表征,通过试验与计算对两种加热方式下沥青混合料加热特性进行分析,采用微观观测并辅以其他试验方法对混合料加热前后理化特性进行探讨。结果表明:钢棉可以增强沥青混合料抗松散性能,但混合料设计时应考虑钢棉的掺入使混合料空隙增大的影响;沥青混合料自愈机理在于混合料内部空隙的重组;微波加热具有较感应加热更好的愈合效果,但微波加热易导致温度过高造成沥青损伤,建议微波加热时间不大于40 s,有条件时应优选感应加热技术。 | 彭文举 张瑶瑶(编译) Norambuena-Contreras J Garcia A | 2019 | 中外公路2019,39,5: | 8 |
| 5 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021,24,8: | 7 |
| 6 | 补体B因子是代谢综合征模型代谢与心血管特征的一个决定因素显示文摘补体B因子(complenment factor B,CFB)在2型糖尿病及心血管病患者脂肪组织及血清中水平升高,但与疾病发病机制的因果关系不明确。自发性高血压大鼠(spontaneously hypertensive rats,SHR)脂肪组织及血清中CFB也升高。为明确CFB在代谢综合征中的作用,研究者在SHR中敲除Cfb基因。 | 赵狄 练桂丽 Coan PM Barrier M Alfazema N Carter RN Marion de Procé S Dopico XC Garcia Diaz A Thomson A Jackson-Jones LH Moyon B Webster Z Ross D Moss J Arends MJ Morton NM Aitman TJ | 2017 | 中华高血压杂志2017,25,8: | 3 |
| 7 | 维生素C和维生素E减轻热应激改善蛋鸡活质量和蛋品质显示文摘试验为研究维生素C和维生素E对热应激下蛋鸡活质量和蛋品质的影响。试验选用720羽39周龄白莱航蛋鸡,随机分为4个处理组,各组分别添加0、150 mg/kg维生素C、150 mg/kg(150 IU)维生素E和150 mg/kg维生素C+150 mg/kg维生素E。试验结束时各试验组的最终活质量、蛋质量、蛋黄质量、蛋清质量和蛋壳质量都显著高于对照组(P<0.05),其中添加维生素C+维生素E组的蛋壳质量最高。通过对蛋鸡活质量和蛋品质指标的跟踪观察发现,抗氧化添加剂的加入能缓解热应激造成的不良影响。 | J J Ajakaiye M Cuesta - Mazorra J R Garcia - Diaz 黄鑫 李彪 谭斌 | 2013 | 饲料研究2013,36,7: | 3 |
| 8 | MRI对糖尿病足部神经血管病变的诊断价值显示文摘目的研究MRI对糖尿病足部神经血管病变的诊断价值。方法 对14例有足部神经血管病变的糖尿病患者行MRI、X-线平片、同位素骨扫描。结果14例患者中10例MRI诊断为血管神经病变。X-线平片无法显示早期骨隋炎,仅在晚期表现为骨质破坏。同位素骨扫描鉴别软组织及骨隋变化较困难。结论 MRI可显示细微解剖结构,诊断糖尿病引起的血管、神经性病变较X-线平片及放射性同位素骨扫描敏感,特异性高,是诊断糖尿病足部神经血管病变的有效方法。 | 刘琰 钱铭辉 Garcia J | 2001 | 实用放射学杂志2001,17,4: | 2 |
| 9 | Nd3+ ion based self frequency doubling solid state lasers显示文摘 | JAQUE D CAPMANY J GARCIA J | 1999 | Optical Materials1999,13,2: | 2 |
| 10 | Measurement of fractional flow reserve to assess moderately severe coronary lesions: correlation with dobutamine stress echocardiography显示文摘 | Jimenez Navarro M Alonso Briales J H Hernandez Garcia M J | 2001 | J Interv Cardiol2001,14,5: | 2 |
| 11 | Gastric cancer in young people under 30 years of age: worse prognosis, or delay in diagnosis?显示文摘 | Horacio N López-Basave Diaz Romero C Alejandro Padilla Rosciano Melchor Ruan J Silvio A. ?amendys-Silva Vela Sarmiento I Ruiz Molina JM Calderillo Ruiz G Flavia Morales-Vásquez Abelardo Meneses Garcia Angel Herrera-Gomez | 2013 | Cancer Management and Research (default)2013,,: | 2 |
| 12 | Magnetic behavior of an array of cobalt nanowires显示文摘 | Garcia J M Asenjo A Velazquez J | 1999 | J Appl Phys1999,85,: | 2 |
| 13 | Long-range magnetostatic interactions in arrays of nanowires显示文摘 | Raposo V Garcia J M Gonzalez J M | 2000 | J Magn Magn Mater2000,222,: | 2 |
| 14 | Programmed cell death of retinal ganglion cells during experimental glaucoma 显示文摘 | Garcia VE Shareef S Walsh J | 1995 | Exp Eye Res1995,61,: | 2 |
| 15 | Assessment of metal contamination in donana national park (spain) using crayfish (proeamburus elarkia) 显示文摘 | Sanchez Lopez F J Gil Garcia M D Martinez Vidal J | 2004 | Environmental Monitoring and Assessment2004,,93: | 1 |
| 16 | Highly sensitive and specific microRNA expression profiling using BeadArray technology显示文摘 | CHEN Jing LOZACH J GARCIA E W | 2008 | Nucleic Acids Res2008,36,14: | 1 |
| 17 | Postprocessing the Galerkin method : a novel approach, to approximate inertial manifolds 显示文摘 | Garcia - Archilla B Novo J Titi E S | 1998 | SIAM Journal on Numerical Analysis1998,35,: | 1 |
| 18 | Cyto toxicity of tumour necrosis factor alpha and gamma interferon against primary human placental trophoblasts 显示文摘 | Yui J Garcia Floret M Wegmann TG | 1994 | Placenta1994,15,8: | 1 |
| 19 | Routing mechanisms for mobile ad hoe networks based on the energy drain rate显示文摘 | Kim D Garcia - Luna - Aceves J Obraezka K | 2003 | IEEE Transactions on Mobile Computing2003,2,2: | 1 |
| 20 | Antimicrobial activity and phytochemical studies of some lichens from south of Spain显示文摘 | SAENZ M T GARCIA M D ROWE J G | 2006 | Fitoterapia2006,77,: | 1 |