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| 1 | Evaluation of three-dimensional biofilms on antibacterial bonding agents containing novel quaternary ammonium methacrylates显示文摘Antibacterial adhesives are promising to inhibit biofilms and secondary caries.The objectives of this study were to synthesize and incorporate quaternary ammonium methacrylates into adhesives,and investigate the alkyl chain length effects on three-dimensional biofilms adherent on adhesives for the first time.Six quaternary ammonium methacrylates with chain lengths of 3,6,9,12,16 and 18were synthesized and incorporated into Scotchbond Multi-Purpose.Streptococcus mutans bacteria were cultured on resin to form biofilms.Confocal laser scanning microscopy was used to measure biofilm thickness,live/dead volumes and live-bacteria percentage vs.distance from resin surface.Biofilm thickness was the greatest for Scotchbond control;it decreased with increasing chain length,reaching a minimum at chain length 16.Live-biofilm volume had a similar trend.Dead-biofilm volume increased with increasing chain length.The adhesive with chain length 9 had 37%live bacteria near resin surface,but close to 100%live bacteria in the biofilm top section.For chain length 16,there were nearly 0%live bacteria throughout the three-dimensional biofilm.In conclusion,strong antibacterial activity was achieved by adding quaternary ammonium into adhesive,with biofilm thickness and live-biofilm volume decreasing as chain length was increased from 3 to 16.Antibacterial adhesives typically only inhibited bacteria close to its surface;however,adhesive with chain length 16 had mostly dead bacteria in the entire three-dimensional biofilm.Antibacterial adhesive with chain length 16 is promising to inhibit biofilms at the margins and combat secondary caries. | Han Zhou Michael D Weir Joseph M Antonucci Gary E Schumacher Xue-Dong Zhou Hockin H K Xu | 2014 | International Journal of Oral Science2014，6，2： | 5 |
| 2 | Low temperature water-gas shift: in situ DRIFTS-reaction study of ceria surface area on the evolution of formats on Pt/CeO2 fuel processing catalysts for fuel cell applications 显示文摘 | Gary Jacobs Leann Williams Uschi Graham Gerald A Pennis E Burtron H D | 2003 | Applied Catalysis A: General2003，252，： | 1 |
| 3 | Influence of intensity, quality, and du- ration of lighter on nitrogen reduction and assimilation in wheat显示文摘 | Jams E H Gary M P | 1968 | Crop Science1968，910，： | 1 |
| 4 | Poliovirus detection in wastewater and stools following an immunization campaign in Havana, Cuba显示文摘 | Mas Lago P Gary H E Perez LS | 2003 | Int J Epidemiol2003，32，： | 1 |
| 5 | XPS and FTIR surface characterization of TiO2 particles used in polymer encapsulation显示文摘 | Bedri E Robert A H Gary W S | 2001 | Langmuir2001，17，： | 1 |
| 6 | Synthesis of a Transition State Analogue Inhibitor of Purine Nucleoside Phosphorylase Via The Mannich Reaction 显示文摘 | Gary B E Richard H F Peter C T | 2003 | Org Lett2003，5，20： | 1 |
| 7 | Hyperbaric oxygen for patients with chronic bowel dysfunction after pelvic radiotherapy (HOT2): a randomised, double-blind, sham-controlled phase 3 trial显示文摘 | Mark Glover Gary R Smerdon H Jervoise Andreyev Barbara E Benton Pieter Bothma Oliver Firth Lone Gothard John Harrison Mihaela Ignatescu Gerard Laden Sue Martin Lauren Maynard Des McCann Christine E L Penny Spencer Phillips Grace Sharp John Yarnold | 2016 | The Lancet Oncology2016，，2： | 1 |
| 8 | The molecular basis of shootresponsos of maize seedlings to Trichoderma harzianum T22 inoculation of the root: a proteomic approach显示文摘 | Shoresh M Gary E H | 2008 | Plant Physiology2008，147，4： | 1 |
| 9 | An epidermal growth factor receptor variant Ⅲ-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme显示文摘 | John H Gary E Duane A | 2009 | Mol Cancer Ther2009，8，10： | 1 |
| 10 | 早期乳腺癌最佳辅助化疗方案与人类表皮生长因子受体2阳性乳腺癌辅助靶向治疗选择:依据 ASCO 对 CCO临床实践指南的改编显示文摘目的研究加拿大安大略癌症治疗中心(CCO)关于早期乳腺癌最佳辅助化疗方案,包括人类表皮生长因子受体2(HER2)阳性乳腺癌辅助靶向治疗方案,并对其进行改编。方法按照美国临床肿瘤协会(ASCO)对其他组织临床实践指南改编的策略和程序,对CCO临床实践指南的严谨性与内容适用性进行回顾。结果基于对CCO临床实践指南内容的回顾,ASCO小组认为,CCO临床实践指南在整体上清晰全面,以最确切的科学证据为基础,为患者提供可接受的治疗选项。推荐关于辅助化疗方案的决定,应考虑到基线复发风险、毒性、利益可能性和宿主因素(如合并症)。对于高风险HER2阴性的身体状况良好的人群,蒽环类和紫杉烷治疗方案是标准治疗方案。4个周期的多西他赛和环磷酰胺治疗方案是可接受的非蒽环类治疗方案。对于高风险HER2阳性患者,推荐蒽环类与紫杉烷序贯疗法联合曲妥单抗或多西他赛、卡铂、曲妥单抗进行6个周期的治疗。对于低风险、非淋巴结转移、HER2阳性人群,推荐每周一次的紫杉醇和曲妥单抗连续进行12个周期的替代治疗。曲妥单抗应持续使用1年。不应采用铂复合盐对三阴性人群进行常规的辅助管理,除非出现有效的生存数据加以支持。 | Neelima Denduluri Mark R Somerfield Andrea Eisen Jamie N Holloway Arti Hurria Tari A King Gary H Lyman Ann H Partridge Melinda L Telli Maureen E Trudeau Antonio C Wolff 本刊编辑部 | 2016 | 中国全科医学2016，19，18： | 1 |
| 11 | Further Evidence on Managerial Motives for Stock Splits 显示文摘 | Baker H Kent Gary E Powell | 1993 | Quarterly Journal of Business and Economics1993，32，3： | 1 |
| 12 | Ultra-Accelerated Weathering System I: Design and Functional Considera- tions显示文摘 | HENRY K H GARY J J CARL E B | 2010 | Material Testing Product and Technology News2010，44，88： | 1 |
| 13 | C-peptide reverses TGF- 13 1-induced changes in renal proximal tubular cells: implications for treatment of diabetic nephropathy显示文摘 | CLAIRE E H GARY B W NIGEL J B | 2009 | Am J Physiol Renal Physiol2009，296，3： | 1 |
| 14 | New strategy for preparing thin gold films on modified glass surfaces by electroless deposition显示文摘 | SABAHUDIN H LIU Ya-li GARY E FARID B JOHN H T | 2003 | Langmuir2003，19，： | 1 |
| 15 | Chemical processing in high-pressure aqueous environments,7:process development for catalytic gasification of wet biomass coal-water slurrys 显示文摘 | Douglas C E Gary G N Todd R H | 2004 | Ind Eng Chem Res2004，43，1： | 1 |
| 16 | Respira- tory syneytial virus is an important cause of community-ac-quired lower respiratory infection among hospitalized adults 显示文摘 | DOWELL S F ANDERSON L J GARY H E et ai | 1996 | Journal of Infectious Diseases1996，174，3： | 1 |
| 17 | Detection of Important Atmospheric and Surface Features by Employing Principal Component Im- age Transformation of GOES Imagery显示文摘 | Donald W H Gary P E | 2003 | Journal of Applied Meteorology2003，42，5： | 1 |
| 18 | Duration of poliovirus excretion and its implications for acute flaccid paralysis surveillance~ a review of the literature显示文摘 | Alexander J P Gary H E Pallansch M A | 1997 | J Infect Dis1997，175，1： | 1 |
| 19 | Solid-state Study of the Hexamethyleneteramine Curing of Phenolic Resins显示文摘 | Galen R H Gary E M | 1987 | Macromolecules1987，20，： | 1 |
| 20 | The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhagditis elegans显示文摘 | Reinhart B J Slack F J Basson M Pasquinelli1 A E Bettinger J C Rougvie A E H Robert Horvitz Gary Ruvkun | 2000 | Nature2000，403，6772： | 1 |
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