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| 1 | MHD and kinetic analysis of flow bursts in the Earth's plasma sheet显示文摘In an attempt to study the flow bursts in the Earth’s plasma sheet we select an event that took place on August 7,2004 in the expansion phase of a substorm,using data from the geomagnetic index,solar wind data,plasma and magnetic field observations from C1 Cluster satellite(the Cluster mission has 4 satellites)and from Double Star TC-1 satellite.In MHD approach,TC-1 firstly observed the tailward flow,then the earthward,and finally the flow alternated in two directions.C1 firstly observed the earthward plasma flow,and then the tailward plasma flow.Before flow bursts are observed by TC-1 and C1,there are disturbances in local entropy with their tailward local entropy larger than those of the earthward.The kinetic features of the plasma flow observed by C1 are similar to those in MHD.However,kinetic characteristics of the plasma flow observed by TC-1 are far more than the description in MHD.The inadequacy mainly exists in two cases:(i)the firstly enhanced tailward flows given in MHD are found without significant increase of the energetic tailward flux;(ii)the almost stagnant flow in MHD is composed of the enhanced energetic ion flux in both earthward and tailward directions.The earthward flow burst observed by TC-1 might be multiple overshoots and rebounds.The earthward flow burst observed by C1 might be simply rebounded in the near-Earth.The pulsation observed by C1 is earlier than that observed by TC-1 with the former intensity less than that of the latter.After the energetic ion flux in the tailward direction is significantly enhanced,the power spectrum intensity of the ULF wave commences to increase obviously,which may suggest that the stream instability is closely correlated with ULF pulsations. | MA YuDuan CAO JinBin FU HuiShan REME H. DANDOURAS I. YANG JunYing WANG ZhiQiang TAO Dan YANG Jian | 2014 | Science China(Technological Sciences)2014，57，1： | 7 |
| 2 | Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly显示文摘Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to ensure chromatid segregation during metaphase-anaphase transition.However,the mechanism underlying the key transition from the mitotic spindle to central spindle before anaphase onset remains elusive.Given the prevalence of chromosome instability phenotype in gastric tumorigenesis,we developed a strategy to model context-dependent cell division using a combination of light sheet microscope and 3D gastric organoids.Light sheet microscopic image analyses of 3D organoids showed that CENP-E inhibited cells undergoing aberrant metaphase-anaphase transition and exhibiting chromosome segregation errors during mitosis.Highresolution real-time imaging analyses of 2D cell culture revealed that CENP-E inhibited cells undergoing central spindle splitting and chromosome instability phenotype.Using biotinylated syntelin as an affinity matrix,we found that CENP-E forms a complex with PRC1 in mitotic cells.Chemical inhibition of CENP-E in metaphase by syntelin prevented accurate central spindle assembly by perturbing temporal assembly of PRC1 to the midzone.Thus,CENP-E-mediated PRC1 assembly to the central spindle constitutes a temporal switch to organize dynamic kinetochore microtubules into stable midzone arrays.These findings reveal a previously uncharacterized role of CENP-E in temporal control of central spindle assembly.Since CENP-E is absent from yeast,we reasoned that metazoans evolved an elaborate central spindle organization machinery to ensure accurate sister chromatid segregation during anaphase and cytokinesis. | Xu Liu Leilei Xu Junying Li Phil Y.Yao Wanjuan Wang Hazrat Ismail Haowei Wang Bryce Liao Zhihong Yang Tarsha Ward Ke Ruan Jianchun Zhang Quan Wu Ping He Xia Ding Dongmei Wang Chuanhai Fu Zhen Dou Feng Yan Wenwen Wang Xing Liu Xuebiao Yao | 2020 | Journal of Molecular Cell Biology2020，12，8： | 3 |
| 3 | Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity显示文摘Triple-negative breast cancer(TNBC)is the most challenging subtype of breast cancer.Various endeavor has been made to explore the molecular biology basis of TNBC.Herein,we reported a novel function of factor Kinectin 1(KTN1)as a carcinogenic promoter in TNBC.KTN1 expression in TNBC was increased compared with adjacent tissues or luminal or Her2 subtypes of breast cancer,and TNBC patients with high KTN1 expression have poor prognosis.In functional studies,knockdown of KTN1 inhibited the proliferation and invasiveness of TNBC both in vitro and in vivo,while overexpression of KTN1 promoted cancer cell proliferation and invasiveness.RNA-seq analysis revealed that the interaction of cytokine-cytokine receptor,particularly CXCL8 gene,was upregulated by KTN1,which was supported by the further experiments.CXCL8 depletion inhibited the tumorigenesis and progression of TNBC.Additionally,rescue experiments validated that KTN1-mediated cell growth acceleration in TNBC was dependent on CXCL8 both in vitro and in vivo.Furthermore,it was found that KTN1 enhanced the phosphorylation of NF-κB/p65 protein at Ser536 site,and specifically bound to NF-κB/p65 protein in the nucleus and cytoplasm of cells.Moreover,the transcription of CXCL8 gene was directly upregulated by the complex of KTN1 and NF-κB/p65 protein.Taken together,our results elucidated a novel mechanism of KTN1 gene in TNBC tumorigenesis and progression.KTN1 may be a potential molecular target for the development of TNBC treatment. | Lin Gao Shanze Chen Malin Hong Wenbin Zhou Bilan Wang Junying Qiu Jinquan Xia Pan Zhao Li Fu Jigang Wang Yong Dai Ni Xie Qinhe Yang Hsien-Da Huang Xiang Gao Chang Zou | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 2 |
| 4 | Double-lipase Catalyzed Synthesis of Kojic Dipalmitate in Organic Solvents显示文摘 | WANG Zhiyuan LUO Wen FU Junying LI Zhibing WANG Zhongming LU Pengmei | 2017 | Chemical Research in Chinese Universities2017，33，6： | 2 |
| 5 | National Alveolar Echinococcosis Distribution--China, 2012−2016显示文摘What is already known about this topic?Both alveolar echinococcosis(AE)and cystic echinococcosis are endemic in China,among which alveolar echinococcosis has a very high mortality rate.What is added by this report?The survey results showed the prevalence and scope of AE in China and identified high-risk groups including children,monks,herdsmen and illiterate people.At the same time,all the cases found in the survey(more than 90%of the patients did not go to the hospital for diagnosis and treatment before survey)were promptly diagnosed and treated.What are the implications for public health practice?This study provides information for the development of a plan for AE prevention and control and for the implementation of interventions targeted to high-risk populations. | Canjun Zheng Chuizhao Xue Shuai Han Zhongjie Li Hu Wang Liying Wang Ying Wang Qian Wang Yu Feng Yanyan Hou Xiao Ma Junying Ma Xiumin Han Gongsang Quzhen Xiaofeng Jiang Weidong Guo Xianglin Wu Yaming Yang Lei Cao Fanka Li Weiqi Chen Xinliu Yan Shicheng Yu Meihua Fu Qing Yu Ning Xiao Jiangping Cao Jun Yan Weiping Wu Xiao-nong Zhou | 2020 | China CDC weekly2020，2，1： | 2 |
| 6 | Wastewater reuse potential analysis: implications for China’s water resources management显示文摘 | Junying Chu Jining Chen Can Wang Ping Fu | 2004 | Water Research2004，，11： | 1 |
| 7 | Bulk glass formation in ternary Cu-Zr-Ti system显示文摘The formation of bulk metallic glasses (BMGs) in ternary Cu-Zr-Ti system was investigated by a copper mold casting method. The nature of the amorphous phase was verified by X-ray diffraction (XRD) and differential scanning calorimetry (DSC). It was demonstrated that the BMGs could be formed in a broad composition range in this system. Cu50Zr42.5Ti7.5, Cu60Zr27.5Ti12.5, Cu60Zr30Ti10 and Cu60Zr32.5Ti7.5 alloys exhibit strong glass-forming ability (GFA), and fully glassy rods of 5 mm in diameter can be obtained. In the center region of the ternary diagram, however, the GFA of the alloys was degraded due to the presence of Laves phase. The degradation of the GFA results from easy nucleation of the Laves phase in the undercooled liquid. | Hua Men, Junying Fu, Chaoli Ma, Shujie Pang, and Tao Zhang Department of Materials Science and Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100083, China | 2007 | International Journal of Minerals,Metallurgy and Materials2007，15，S1： | 1 |
| 8 | Formation and thermal stability of Cu-Zr-Al-Er bulk metallic glasses with high glass-forming ability显示文摘The formation and thermal stabilities of Cu46.25Zr46.25xAl7.5Erx (x=0 to 8) bulk metallic glasses (BMGs) were investigated. The addition of a small amount of Er (2at%) for replacing Zr effectively improves the glass-forming ability of Cu46.25Zr46.25Al7.5 alloy, and the glassy rod with a diameter of at least 12 mm can be formed. The glass transition temperature (Tg), temperature interval of su- percooled liquid region △Tx (=Tx-Tg), and reduced glass transition temperature Trg (=Tg/Tl) of Cu46.25Zr44.25Al7.5Er2 glassy alloy are 699 K, 62 K and 0.607, respectively. | Junying Fu, Hua Men, Shujie Pang, Chaoli Ma, and Tao Zhang Department of Materials Science and Engineering, Behang University, Beijing 100083, China | 2007 | International Journal of Minerals,Metallurgy and Materials2007，15，S1： | 1 |
| 9 | Wastewater reuse potential analysis: implications for China's water resources management显示文摘 | Junying Chu Jining Chen Can Wang Ping Fu | 2004 | Water Research2004，，38： | 1 |
| 10 | Formation and thermal stability of Cu-Zr-Al-Er bulk metallic glasses with high glass-forming ability 显示文摘 | Fu Junying Men Hua Pang Shujie Ma Chaoli Zhang Tao | 2007 | Journal of University of Science and Technology Beijing Mineral Metallurgy Material2007，14，： | 1 |
| 11 | Research on the construction and practice of the evaluation system of postgraduate supervision显示文摘In recent years,with the rapid development and expansion of postgraduate education in China,the cultivation quality has become increasingly prominent.In graduate education activities,there are many factors that affect the quality of cultivation,among which the tutor’s guiding ability is undoubtedly the key factor that affects the quality of graduate students’cultivation.In the 2020 National Graduate Education Conference,one of its topics is how to objectively quantify the guiding ability of supervisors based on which the teaching resources can be optimally allocated.Taking Hangzhou Dianzi University as an example,this paper investigates the index systems to evaluate the guiding ability of graduate students’supervisors including 6 first-level indicators and 19 second-level indicators in order to further improve the cultivation performance of graduate students. | Wanzeng Kong Yong Peng Hongwen Du Jianjiang Pan Junying Fu JiangrongXu | 2022 | Data Science and Informetrics2022，2，3： | 1 |
| 12 | FTIR study of pyrolysis products evolving from typical agricultural residues显示文摘 | Peng Fu Song Hu Jun Xiang Peisheng Li Dan Huang Long Jiang Anchao Zhang Junying Zhang | 2010 | Journal of Analytical and Applied Pyrolysis2010，，2： | 1 |
| 13 | PML–LRIF1 interactions form a novel link between promyelocytic leukemia bodies and centromeres显示文摘Dear Editor,Promyelocytic leukemia(PML)is the scaffold protein that organizes PML bod-ies,which are nuclear membraneless organelles involved in various biologi-cal processes,including tumor suppres-sion and antiviral responses(Ugge et al.,2022).Early electron microscopic analy-ses revealed contacts between the sur-face of PML bodies and chromatin struc-ture(Corpet et al.,2020).In fact,sev-eral chromatin and cell cycle regulators,such as TIP60,P300,and heterochro-matin protein 1(HP1),are localized in PML bodies in interphase cells(Corpet et al.,2020). | Junying Li Xiao Yuan Fengrui Yang Jun Cao Chunyue Wang Saima Akram Peng Zou Felix Aikhionbare Xuejun Li Yong Chen Liangyu Zhang Chuanhai Fu Zhikai Wang Xing Liu Xuebiao Yao | 2023 | Journal of Molecular Cell Biology2023，15，6： | 0 |
| 14 | PREPARATION OF Al-Si INGOTS WITH FULL EUTECTIC-LIKE MICROSTRUCTURE AT LOW COOLING RATE显示文摘PREPARATIONOFAl-SiINGOTSWITHFULLEUTECTIC-LIKEMICROSTRUCTUREATLOWCOOLINGRATEWEIPengyi;FUHengzhi(StateKeyLaboratoryofSolidifica... | WEI Pengyi FU Hengzhi(State Key Laboratory of Solidification Processing,Northwestern Polytechnical University,Xi’an 710072,China) W.REIF(Institute fuer Metallforshung-Metallkunde,Technische Universitaete Berlin,Strasse des 17 Juni 135,D-1000 Berlin 12,Ger | 1996 | Acta Metallurgica Sinica(English Letters)1996，9，1： | 0 |
| 15 | Properties and nucleotide sequence of linear plasmid-like DNA pC4 from mitochondria of Cucumis sativus显示文摘Four kinds of mitochondrial plasmid-like DNAs, designated pC1, pC2, pC3 and pC4, were detected in Cucumis sativus Jinyan No. 4. The electron microscopy observation showed that pC4 was linear conformation. Complete sequence of pC4 was cloned into pUC19 with E. coli JM109 as host. Sequence analysis revealed that pC4 was 370 bp long, the shortest one among all the reported mitochondrial plasmid-like DNAs. pC4 was AT rich. It contained terminal direct repeat sequence (35 bp in length)as well as many short direct and inverted repeats. ORFs in pC4 were short. pC4 was found to be homologous to nuclear DNAs, but lack homology with main mitochondrial and chloroplast DNAs. pC4-homologous sequence also occurred in nuclear genome of Jinyan No. 7 which contained no mitochondrial plasmid-like DNAs. The hybridization pattern of Jinyan No. 7 was slightly different from that of Jinyan No. 4. This suggested that pC4 occurred at the forepart of Cucumis sativus species divergence and integrated into the nuclear genome, | Junying Li Yingda Wen Yanling Bai Juan Fu Xiuming Zhang Caichang Gao | 2001 | Chinese Science Bulletin2001，46，15： | 0 |
| 16 | Facile construction of aggregation-induced emission molecular liquids via Piers-Rubinsztajn reaction for green fluorescent ink显示文摘Solvent-free luminescent molecular liquids(LMLs), which exhibit nonvolatile fluidic nature and active optoelectronic properties, were widely used. For further development, we introduced siloxane units into AIE molecules, designed and synthesized TPE derivatives with siloxane side chains via facile Piers-Rubinsztajn reaction. The obtained AIE molecular liquids exhibit unique photophysical properties. Compared with the obtained alkyl TPE-solids, siloxane TPE show liquid state, which proves that the siloxane units have stronger liquefaction effect than alkyl. Viscosity test shows that siloxane TPE-liquids has far more lower viscosity and better fluidity than the long-chain alkyl molecular liquids in previous research. All those properties are attributed to the weak interaction between flexible molecular chains of siloxane. Besides,fluorescence test shows temperature responsiveness of siloxane TPE-liquids. We developed this lowviscosity nonvolatile AIE molecular liquid as green fluorescent ink. | Rong Fu Longyue Yu Junying Zhang Huidong Yu Shengyu Feng Xing-Dong Xu | 2022 | Chinese Chemical Letters2022，33，4： | 0 |
| 17 | 近30年中医药研究全球发展概况显示文摘中医药主要包括三个方面,即中医、中药和针灸,且因其显著的医疗价值逐渐引起广泛重视。采用文献计量分析法对关于中医药以及其分支研究的文献进行分析,数据来源于1980-2009年科学引文扩展数据库,共收录16536篇相关文献。统计结果显示,关于针灸的文献数量呈明显下降趋势,而关于中医和中药的文献数量则大幅上升。东亚地区是发表中医药文献最多的区域,紧随其后的是北美和欧洲。虽然在东亚各国中,中国是发表中医药文献最多的国家,但是美国的文献引用率居全球首位;东亚学者的研究重点在于中药,而北美和欧洲各国则更重视针灸的研究。在过去的30年中,中国取代日本成为中医药研究第一大国,而美国则继续保持其在针灸研究方面的优势并保持上升态势。在所有研究中医药的科研机构中,中国科学院居于首位,韩国庆熙大学发表的关于针灸的文献最多,而美国哈佛大学发表的关于针灸的文献引用率最高。 | Fu Junying Zhang Xu Zhao Yunhua Chen Darzen Huang Musuan 本刊编辑 | 2013 | 亚太传统医药2013，9，10： | 0 |
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