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| 1 | Model for end-stage liver disease score versus Child score in predicting the outcome of surgical procedures in patients with cirrhosis显示文摘AIM:To determine factors affecting the outcome of patients with cirrhosis undergoing surgery and to compare the capacities of the Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD)score to predict that outcome. METHODS:We reviewed the charts of 195 patients with cirrhosis who underwent surgery at two teaching hospitals over a five-year period.The combined endpoint of death or hepatic decompensation was considered to be the primary endpoint. RESULTS:Patients who reached the endpoint had a higher MELD score,a higher CTP score and were more likely to have undergone an urgent procedure.Among patients undergoing elective surgical procedures,no statistically significant difference was noted in the mean MELD(12.8±3.9 vs 12.6±4.7,P=0.9)or in the mean CTP(7.6±1.2 vs 7.7±1.7,P=0.8)between patients who reached the endpoint and those who did not.Both mean scores were higher in the patients reaching the endpoint in the case of urgent procedures(MELD:22.4± 8.7 vs 15.2±6.4,P=0.0007;CTP:9.9±1.8 vs 8.5±1.8, P=0.008).The performances of the MELD and CTP scores in predicting the outcome of urgent surgery were only fair,without a significant difference between them (AUC=0.755±0.066 for MELD vs AUC=0.696±0.070 for CTP,P=0.3). CONCLUSION:The CTP and MELD scores performedequally,but only fairly in predicting the outcome of urgent surgical procedures.Larger studies are needed to better define the factors capable of predicting the outcome of elective surgical procedures in patients with cirrhosis. | Maarouf A Hoteit Amaar H Ghazale Andrew J Bain Eli S Rosenberg Kirk A Easley Frank A Anania Robin E Rutherford | 2008 | World Journal of Gastroenterology2008，14，11： | 16 |
| 2 | Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial显示文摘 | Paul Y Kwo Eric J Lawitz Jonathan McCone Eugene R Schiff John M Vierling David Pound Mitchell N Davis Joseph S Galati Stuart C Gordon Natarajan Ravendhran Lorenzo Rossaro Frank H Anderson Ira M Jacobson Raymond Rubin Kenneth Koury Lisa D Pedicone Clifford | 2010 | The Lancet2010，，9742： | 3 |
| 3 | Stomach contents of juvenile Cobia, Rachycentron canadum, from the northern Gulf of Mexico 显示文摘 | Franks J S Garber N M Warren J R | 1996 | Fishery Bulletin1996，94，2： | 1 |
| 4 | A conformationally sensitive GHR antibody : impact on GH signaling and GHR proteolysis显示文摘 | Jiang J Wang X He K Li X Chen C M Sayeski P P Waters M J Frank S J | 2004 | Mol Endocrinol2004，18，12： | 1 |
| 5 | Plankton patchiness in highfrequency internal waves 显示文摘 | Lennert Cody C E Franks P J S | 1999 | Marine Ecology Progress Series1999，186，： | 1 |
| 6 | Expressional regulation of angiopoietin-1 and -2 and the tie-I and -2 receptor tyrosine kinazes during cutaneous wound healing: a comparative study of normal and impaired repair 显示文摘 | Kampfer H Pfeilschifter J Frank S | 2001 | Lab hwest2001，81，3： | 1 |
| 7 | Mutiresidue determination of abamectin, doramectin, ivermectin and moxidectin in milk using liquid chromatography and fluorescence detection 显示文摘 | Frank J S Lawence H L | 1999 | J AOAC Int1999，82，： | 1 |
| 8 | Ionospheric Imaging Using Computerized Tomography显示文摘 | Austen J R Franke S J Liu C H | 1988 | Radio Science1988，23，3： | 1 |
| 9 | Motor Learning of a Dynamic Balancing Task After Stroke:Implicit Implications for Stroke Rehabilitation显示文摘 | Alison J Otrell Frank F Eves Rich S W Masters | 2006 | Physical Theropy2006，3，86： | 1 |
| 10 | Multi-objective conditioning of a simple SVAT model显示文摘 | Franks S W Beven K J Gash H C | 1999 | Hydrology and Earth System Sciences1999，3，4： | 1 |
| 11 | Follicle dynamics and anovulation in polycystic ovary syndrome显示文摘 | Franks S Stark J Hardy K | 2008 | Hum Reprod Update2008，14，4： | 1 |
| 12 | Induction of inducible nitric oxide synthase and its corresponding tetrahydrobiopterin-cofactor-synthesizing enzyme GTP-cyclohydrolase I during cutaneous wound repair显示文摘 | Frank S Madlener M Pfeilschifter J | 1998 | J Invest Dermatol1998，111，6： | 1 |
| 13 | Direct Analysis of Oxidizing Agents in Aqueous Solution with Attenuated Total Reflectance Mid-Infrared Spectroscopy and Diamond-like Carbon Protected Waveguides显示文摘 | MARKUS J FRANK V VORABERGER H S | 2004 | Analytical Chemistry2004，76，2： | 1 |
| 14 | Ovulatory disorders in women with polycystic ovary syndrome显示文摘 | Frank S Adam J Mason H | 1985 | Clin Obstet Gynecol1985，12，3： | 1 |
| 15 | Growth Hormone-induced JAK2 Signaling and GH Receptor Down-regulation:Role of GH Receptor Intraeellular Domain Tyrosine Residues显示文摘 | Deng L Jiang J Frank S J | 2012 | Endo- crinology2012，153，5： | 1 |
| 16 | Growth hormone receptor is a target for presenilin-dependent gam- ma-secretase cleavage 显示文摘 | Cowan J W Wang X D Guan R He K Jiang J Baumann G Black R A Wolfe M S Frank S J | 2005 | J Biol Chem2005，280，19： | 1 |
| 17 | Application of Computerized Tomography to Investigation of Ionospheric Structures 显示文摘 | Raymund T D Austen J R Franke S J | 1990 | Radio Science1990，25，5： | 1 |
| 18 | Trophic cascades in a formerly cod-Dominated ecosystem 显示文摘 | Frank K T Petrie B Choi J S | 2005 | Science2005，308，10： | 1 |
| 19 | Reverse engineering of scalp- tured surfaces by four-axis non-contacting scanning显示文摘 | WANG G J WANG C C FRANK S H | 1999 | The internation- al journal of Advanced Manufacturing Technology1999，，15： | 1 |
| 20 | Clinically applicable labeling of mammalian and stem cells by combining superparamagnetic iron oxides and transfection agents显示文摘 | Frank J A Miller B R Arbab A S | 2003 | Radiology2003，228，： | 1 |
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