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| 1 | Chitosan tubes enriched with fresh skeletal muscle fibers for delayed repair of peripheral nerve defects显示文摘Nerve regeneration after delayed nerve repair is often unsuccessful. Indeed, the expression of genes associated with regeneration, including neurotrophic and gliotrophic factors, is drastically reduced in the distal stump of chronically transected nerves; moreover, Schwann cells undergo atrophy, losing their ability to sustain regeneration. In the present study, to provide a three-dimensional environment and trophic factors supporting Schwann cell activity and axon re-growth, we combined the use of an effective conduit(a chitosan tube) with a promising intraluminal structure(fresh longitudinal skeletal muscle fibers). This enriched conduit was used to repair a 10-mm rat median nerve gap after 3-month delay and functional and morphometrical analyses were performed 4 months after nerve reconstruction. Our data show that the enriched chitosan conduit is as effective as the hollow chitosan conduit in promoting nerve regeneration,and its efficacy is not statistically different from the autograft, considered the 'gold standard' technique for nerve reconstruction. Since hollow tubes not always lead to good results after long defects(> 20 mm), we believe that the conduit enriched with fresh muscle fibers could be a promising strategy to repair longer gaps, as muscle fibers create a favorable three-dimensional environment and release trophic factors. All procedures were approved by the Bioethical Committee of the University of Torino and by the Italian Ministry of Health(approval number: 864/2016/PR) on September 14, 2016. | AlessANDro Crosio Benedetta Elena Fornasari Giovanna Gambarotta Stefano Geuna Stefania Raimondo Bruno Battiston Pierluigi Tos Giulia Ronchi | 2019 | Neural Regeneration Research2019，14，6： | 2 |
| 2 | Bimanual microincision cataract surgery with implantation of the new Incise~? MJ14 intraocular lens through a 1.4 mm incision显示文摘AIM: To analyze the visual outcomes and the posterior capsule opacification(PCO) with the new Incise? MJ14 intraocular lens(IOL) implanted through a 1.4 mm clear corneal incision(CCI) in patients who underwent bimanual microincision cataract surgery(B-MICS). METHODS: Eighty eyes which underwent cataract surgery using B-MICS technique performed by the same experienced surgeon were included in the study: 40 eyes were implanted with an Incise? MJ14 IOL through a 1.4 mm CCI(group A)without enlargement of the main CCI, while 40 eyes were implanted with an Akreos? MI60 IOL with enlargement of the main CCI to 1.8 mm(group B). Best corrected visual acuity(BCVA), astigmatism and endothelial cell loss were evaluated before and after surgery at 7, 30 d and 6 mo.Anterior segment-optical coherence tomography(AS-OCT) of CCI was performed at 1, 3, 7, 30 d, 6 and 18 mo. PCO incidence was evaluated at 18 mo using EPCO 2000 Software. RESULTS: Mean BCVA improvement and endothelial cell loss were statistically significant at 18 mo in both groups with no difference between the two groups; no statistically significant difference in surgically induced astigmatism(SIA) was noticed in the two groups. At AS-OCT the only significant alterations in the CCI were endothelial gaping and local detachment of Descemet's membrane at 1 and 7 d after surgery; no statistically significant alterations were found at 1, 6 and 18 mo. PCO score at 18 mo was 0.03±0.07 for group A and 0.08±0.18 for group B(P=0.11) with no sign of central optic plate invasion in both groups.CONCLUSION: The implant of the new Incise? MJ14 IOL through a 1.4 mm CCI and B-MICS technique appeared to be a safe and effective procedure with rapid visual recovery. PCO rate resulted very low and the CCI presented few morphological alterations which were only detectable in the first days postoperatively and achieved fast corneal healing during the long-term follow-up. | Gian Maria Cavallini Tommaso Verdina Michele De Maria Elisa Fornasari Giulio Torlai Veronica Volante Simone Donati Carlo Cagini | 2017 | International Journal of Ophthalmology(English edition)2017，10，11： | 2 |
| 3 | TS-1 catalytic mechanism in cyclohexanone oxime production显示文摘 | Dal Pozzo L Fornasari G Monti T | 2002 | Catal Commun2002，，3： | 1 |
| 4 | Synthesis of hydrotalcite - type compounds containing noble metals显示文摘 | Basile F Fornasari G and thermal evolution Gazza M | 2000 | Applied Clay Science2000，16，： | 1 |
| 5 | General anesthesia versus spinal anesthesia for laparoscopic cholecystectomy显示文摘 | Imbelloni LE Fornasari M Fialho JC | 2010 | Rev Bras Anestesiol2010，60，3： | 1 |
| 6 | Vapor phase Beck mann rearrangement using high silica zeolite catalyst显示文摘 | ForniL Fornasari G Giordano G | 2004 | Phys Chem Chem Phys2004，，6： | 1 |
| 7 | Improved modeling of Sigma-Delta modulator non idealities in Simulink显示文摘 | Fornasari A Malcovati P Maloberti F | 2005 | IEEE Circuits and Systems2005，6，： | 1 |
| 8 | Gain and offset mismatch calibration in time-interleaved multipath A/D sigma-delta modulators显示文摘 | Ferragina Vincenzo Fornasari | 2004 | IEEE Transactions on Circuits and Systems I:Regular Papers2004，51，12： | 1 |
| 9 | Partial oxidation of methane:Effect of reaction parameters and catalyst composition on the thermal profile and heat distribution显示文摘 | SILE F FORNASARI G TRIFIRO F VACCARI A | 2001 | Catal Today2001，64，12： | 1 |
| 10 | Progenitor cell isolation from muscle-derived cells based on adhesion properties显示文摘 | Rouger K Fornasari B Armengol V | 2007 | J Histochem Cytochem2007，55，6： | 1 |
| 11 | Functional properties of muscle-derived cells related to morphological characteristics 显示文摘 | Jouvion G Rouger K Fornasari B | 2006 | Histochem Cell Biol2006，126，5： | 1 |
| 12 | Hydrotalcite-type precursors of active catalysts for hydrogen production显示文摘 | Basile F Benito P Fornasari G | 2010 | Applied Clay Science2010，48，1： | 1 |
| 13 | TS-1,catalytic mechanism in cyclohexanone oxime producfion显示文摘 | Dal Pozzo L Fornasari G Monti T | 2002 | Catalysis Communication2002，3，： | 1 |
| 14 | Virtual reality in autism: state of the art显示文摘 | Bellani M Fornasari L Chittaro L | 2011 | Epidemiol Psychiatr Sci2011，20，3： | 1 |
| 15 | Deactivation of a Pt/γ-Al 2 O 3 catalyst in the partial oxidation of methane to synthesis gas显示文摘 | S Albertazzi P Arpentinier F Basile P Del Gallo G Fornasari D Gary A Vaccari | 2003 | Applied Catalysis A General2003，，1： | 1 |
| 16 | On the mechanism of n-butane oxidation to maleic anhydride: Oxidation in oxygen-stoichiometry-controlled conditions显示文摘 | Centi G Fornasari G Trifiro F | 1984 | J Catal1984，89，： | 1 |
| 17 | Deactivation of a Pt/α-Al2O3 catalyst in the partial oxidation of methane to synthesis gas显示文摘 | Albertazzi S Arpentinier P Basile F Del Gallo P Fornasari G Gary D Vaccari A | | 0，，： | 1 |
| 18 | Synthesis and thermal evolution of hydrotalcite-type compounds containing noble metals 显示文摘 | Fornasari G Gazzano M | 2000 | Appl Clay Sci2000，16，： | 1 |
| 19 | NOx storage- reduction catalysts based on hydrotalcite Effect of Cu in printing resistance to deactivation显示文摘 | G Centin G Fornasari C Gobbi | 2002 | Catal Today2002，73，34： | 1 |
| 20 | Human mesenchymat stem cells:A bank perspective on the isolation, characterization and poten- tial of alternative sources {or the regeneration of musculoskel- etal tissues显示文摘 | Moron L Fornasari PM | 2013 | J Cell Physiol2013，228，4： | 1 |
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