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2篇 您的检索式:作者名="Ferran Bolao"
    题名 作者 年代 出处 被引量
1Alcohol use disorder and its impact on chronic hepatitis C virus and human immunodeficiency virus infections显示文摘Alcohol use disorder(AUD) and hepatitis C virus(HCV) infection frequently co-occur. AUD is associated with greater exposure to HCV infection, increased HCV infection persistence, and more extensive liver damage due to interactions between AUD and HCV on immune responses, cytotoxicity, and oxidative stress. Although AUD and HCV infection are associated with increased morbidity and mortality, HCV antiviral therapy is less commonly prescribed in individuals with both conditions. AUD is also common in human immunodeficiency virus(HIV) infection, which negatively impacts proper HIV care and adherence to antiretroviral therapy, and liver disease. In addition, AUD and HCV infection are also frequent within a proportion of patients with HIV infection, which negatively impacts liver disease. This review summarizes the current knowledge regarding pathological interactions of AUD with hepatitis C infection, HIV infection, and HCV/HIV co-infection, as well as relating to AUD treatment interventions in these individuals.Daniel Fuster Arantza Sanvisens Ferran Bolao Inmaculada Rivas Jordi Tor Robert Muga 2016World Journal of Hepatology2016,8,31:4
2Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use显示文摘Hepatitis C virus(HCV)infection and unhealthy alcohol use are major drivers of the burden of liver disease worldwide and commonly co-occur.Assessment of underlying liver damage is a cornerstone of the clinical care of patients with chronic HCV infection and/or unhealthy alcohol use because many of them are diagnosed at advanced stages of disease.Early diagnosis of liver disease before decompensated liver cirrhosis becomes established is essential for treatment with direct acting antivirals and/or abstinence from alcohol consumption,which are the main therapeutic approaches for clinical management.In this review,we discuss current knowledge around the use of non-invasive methods to assess liver disease,such as abdominal ultrasound,controlled attenuation parameter,transient elastography,magnetic resonance imaging,and indices based on serum markers of liver injury.Daniel Fuster Xavier García-Calvo Paola Zuluaga Ferran Bolao Robert Muga 2021World Journal of Gastroenterology2021,27,23:0
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