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| 1 | Altered blood-brain barrier permeability in rats with prehepatic portal hypertension turns to normal when portal pressure is lowered显示文摘AIM: To study the blood-brain barrier integrity in prehe-patic portal hypertensive rats induced by partial portal vein ligation, at 14 and 40 d after ligation when portal pressure is spontaneously normalized. METHODS: Adult male Wistar rats were divided into four groups: GroupⅠ: Sham14d, sham operated; GroupⅡ: PH14d, portal vein stenosis; (both groups were used 14 days after surgery); GroupⅢ: Sham40d, Sham operated and GroupⅣ: PH40d Portal vein stenosis (GroupsⅡandⅣused 40 d after surgery). Plasma ammonia, plasma and cerebrospinal fluid protein and liver enzymes concentrations were determined. Trypan and Evans blue dyes, systemically injected, were investigated in hippocampus to study blood-brain barrier integrity. Portal pressure was periodically recorded. RESULTS: Forty days after stricture, portal pressure was normalized, plasma ammonia was moderately high, and both dyes were absent in central nervous system parenchyma. All other parameters were reestablished. When portal pressure was normalized and ammonia level was lowered, but not normal, the altered integrity of blood-brain barrier becomes reestablished. CONCLUSION: The impairment of blood-brain barrier and subsequent normalization could be a mechanism involved in hepatic encephalopathy reversibility, Hemo-dynamic changes and ammonia could trigger blood-brain barrier alterations and its reestablishment. | Francisco Eizayaga Camila Scorticati Juan P Prestifilippo Salvador Romay Maria A Fernandez José L Castro Abraham Lemberg Juan C Perazzo | 2006 | World Journal of Gastroenterology2006，12，9： | 3 |
| 2 | Histological and molecular classification of gliomas显示文摘Rev Neurol (Paris). 2008 June-July;164(6-7):505-515. Epub 2008 Jun 10.Gliomas are the most frequent tumors of the central nervous system. The WHO classification, based on the presumed cell origin,distinguishes astrocytic,oligodendrocytic and mixed gliomas. A grading system is based on the presence of the following criteria: in- | Figarella-Branger D Colin C Coulibaly B Quilichini B Maues De Paula A Fernandez C Bouvier C | 2008 | 中国神经肿瘤杂志2008，6，2： | 3 |
| 3 | Occurrence of Organochlorine Insecticides, PCBs and PCB Congeners in waters and Sediments of the Ebro River (Spain) 显示文摘 | Fernandez M A Alonso C Gonzalez M J | 1999 | Chemosphere1999，38，： | 2 |
| 4 | Comparison of solid-phase microextraction and stir bar sorptive extraction for determining six organophosphorus insecticides in honey by liquid chromatography-mass spectrometry显示文摘 | BLASCO C FERNANDEZ M PICO Y | 2004 | Journal of Chromatography A2004，1030，12： | 1 |
| 5 | Role of ischemic preconditioning and the portosystemic shunt in the prevention of liver and lung damage after rat liver transplantation显示文摘 | Fernandez L Heredia N Peralta C | 2003 | Transplantation2003，76，2： | 1 |
| 6 | Tip grafts in closed rhiiloplasty:insertion and fixation made easy显示文摘 | FERNANDEZ D E da SIL VA CARVALHO G | 2008 | Plast Reconstr Surg2008，121，3： | 1 |
| 7 | Biotransformation of ent-13-ePimanoyl,oxides difunetionalizedat C-3 and C-12 by filamentous fungi显示文摘 | Andres Garcia-Granados Antonia Fernandez Maria C Gutierrez | 2004 | Phytoehemistry2004，65，： | 1 |
| 8 | Molecular characterization of a novel 8 kDa subunit of Echinococcus granulosus antigen B显示文摘 | Fernandez V Ferreira HB Fernandez C | 1996 | Mol Biochem Parasitol1996，77，2： | 1 |
| 9 | Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis显示文摘 | Suarez Y Fernandez Hernando C Yu J | 2008 | Proc Natl Acad Sci USA2008，105，14： | 1 |
| 10 | Dendritic cells directly trigger NK cell functions:cross-talk relevant in innate anti-tumor immune responses in vivo显示文摘 | Fernandez NC Lozier A Flament C | 1999 | Nat Med1999，5，4： | 1 |
| 11 | Investigation on the role played by fermentation esters in the aroma of young Spanish wines by multivariate analysis显示文摘 | FERREIRA V FERNANDEZ P PENA C ct al | 1995 | J Sci Food Agr1995，67，3： | 1 |
| 12 | Optimization of sparse matrix-vector multiplication using reordering techniques on GPUs显示文摘 | PICHEL J C RIVIERA F F FERNANDEZ M | 2012 | Microprocessors and Microsystems2012，36，2： | 1 |
| 13 | Materials used as PCM in thermal energy storage in buildings: a review 显示文摘 | Cabeza E Castell A Barreneche C Graeia A Fernandez A | 2011 | Renewable and Sustainable Energy Reviews2011，15，3： | 1 |
| 14 | Oral contra-ceptives and colorectal cancer risk:a meta-analysis显示文摘 | Fernandez E La Vecchia C Balducci A | 2001 | Br J Cancer2001，84，5： | 1 |
| 15 | Effect of corticosteroids on the clinical course of community - acquired pneumonia: a randomized controlled trial显示文摘 | Fernandez - Serrano S Dorca J Garcia - Vidal C | 2011 | Crti Care2011，15，2： | 1 |
| 16 | Nanostructured Oxides in Chemistry显示文摘 | Fernandez G M Martinez A A Hanson J C | 2004 | Chem Rev2004，104，： | 1 |
| 17 | Neonatal chylothorax: aetinlogy, clini-cal course and efficacy of treatment显示文摘 | Capons Fernandez C Benifez Segura I Castillo Salinas F Salcedo Ahizanda S | 2008 | An Pediatr (Barc)2008，68，3： | 1 |
| 18 | Diagnosis and management of intramural ectopic pregnancy显示文摘 | Bannon K Fernandez C Rojas D et td | 2013 | I Minim Invasive Gynecol2013，20，5： | 1 |
| 19 | Analysis of wind power generation andprediction using ANN :a case study 显示文摘 | Mabel M C Fernandez E | 2008 | Renewable Energy2008，，33： | 1 |
| 20 | Biotic and abiotic causes of yield failure in tropical aerobic rice显示文摘 | Kreye C Bouman B A M Reversat G Fernandez L Faronilo J E Llorca L | | 0，，： | 1 |
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