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1Ultrasonically activated scalpel versus monopolar electrocautery shovel in laparoscopic total mesorectal excision for rectal cancer显示文摘AIM: To investigate the feasibility and safety of monopolar electrocautery shovel (ES) in laparoscopic total mesorectal excision (TME) with anal sphincter preservation for rectal cancer in order to reduce the cost of the laparoscopic operation, and to compare ES with the ultrasonically activated scalpel (US). METHODS: Forty patients with rectal cancer, who underwent laparoscopic TME with anal sphincter preservation from June 2005 to June 2007, were randomly divided into ultrasonic scalpel group and monopolar ES group, prospectively. White blood cells (WBC) were measured before and after operation, operative time, blood loss, pelvic volume of drainage, time of anal exhaust, visual analogue scales (VAS) and surgery-related complications were recorded. RESULTS: All the operations were successful; no one was converted to open procedure. No significant differences were observed in terms of preoperative and postoperative d 1 and d 3 WBC counts (P = 0.493, P = 0.375, P = 0.559), operation time (P = 0.235), blood loss (P = 0.296), anal exhaust time (P = 0.431), pelvicdrainage volume and VAS in postoperative d 1 (P = 0.431, P = 0.426) and d 3 (P = 0.844, P = 0.617) between ES group and US group. The occurrence of surgery-related complications such as anastomotic leakage and wound infection was the same in the two groups. CONCLUSION: ES is a safe and feasible tool as same as US used in laparoscopic TME with anal sphincter preservation for rectal cancer on the basis of the skillful laparoscopic technique and the complete understanding of laparoscopic pelvic anatomy. Application of ES can not only reduce the operation costs but also benef it the popularization of laparoscopic operation for rectal cancer patients.Bao-Jun Zhou, Wei-Qing Song, Qing-Hui Yan, Jian-Hui Cai, Feng-An Wang, Jin Liu, Guo-Jian Zhang, Guo-Qiang Duan, Zhan-Xue Zhang, Department of Gastrointestinal Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China Author contributions: Zhou BJ, Song WQ, Yan QH, Cai JH, Wang FA, Liu J, Zhang GJ, Duan GQ and Zhang ZX contributed equally to this work Zhou BJ, Song WQ, Yan QH, Cai JH and Wang FA designed the research Zhou BJ, Liu J and Zhang GJ performed the research Duan GQ and Zhang ZX analyzed the data and Zhou BJ, Song WQ and Yan QH wrote the paper. 2008World Journal of Gastroenterology2008,14,25:25
2Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu 2018Molecular Plant2018,11,8:14
3Transient expression and antigenic characterization of HBsAg of HBV nt551 A to G mutant显示文摘NTRODUCTIONFromthelate80s,therehavebeenincreasingnumberofreportsonhepatitisB(HB)patientswithatypicalHBVserologicalmarkers,so...FANG De Xing 1, LI Fa Qing 1, TAN Wei Guo 1, CHEN Hua Biao 1, JIN Hui Ying 1, LI Su Qin 1, LIN Hou Ji 2 and ZHOU Zhen Xian 2 1999World Journal of Gastroenterology1999,5,1:10
4The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population显示文摘导致噪音的听觉损失(NIHL ) 是在环境、基因的因素之间的相互作用引起的复杂疾病。这研究调查了在 protocadherin 的基因可变性是否联系了 15 (PCDH15 ) 在一张中国人口位于增加的危险性下面到 NIHL 的发展。结果证明与 rs11004085 的 TT 遗传型相比, CT/CC 遗传型与 NIHL 的增加的风险被联系[调整机会比率(或)= 2.64;95% 信心间隔(CI ) :1.14-6.11, P = 0.024 ] 。另外,在 rs11004085 和 rs978842 之间的重要相互作用基因变化和噪音暴露在高级暴露组被观察(P < 0.05 ) 。而且,当与噪音暴露的高水平结合了时,风险 haplotype TAGCC 被观察(P < 0.05 ) 。因此,我们的学习证实在 PCDH15 的基因变化在人修改危险性到 NIHL 开发。XU Xiang Rong WANG Jing Jing YANG Qiu Yue JIAO Jie HE Li Hua YU Shan Fa GU Gui Zhen CHEN Guo Shun ZHOU Wen Hui WU Hui LI Yan Hong ZHANG Huan Ling ZHANG Zeng Rui JIN Xian Ning 2017Biomedical and Environmental Sciences2017,30,2:9
5Co-effect of Demand-control-support Model and Effort-reward Imbalance Model on Depression Risk Estimation in Humans: Findings from Henan Province of China显示文摘Objective To investigate the co-effect of Demand-control-support(DCS) model and Effort-reward Imbalance(ERI) model on the risk estimation of depression in humans in comparison with the effects when they are used respectively. Methods A total of 3 632 males and 1 706 females from 13 factories and companies in Henan province were recruited in this cross-sectional study. Perceived job stress was evaluated with the Job Content Questionnaire and Effort-Reward Imbalance Questionnaire(Chinese version). Depressive symptoms were assessed by using the Center for Epidemiological Studies Depression Scale(CES-D). Results DC(demands/job control ratio) and ERI were shown to be independently associated with depressive symptoms. The outcome of low social support and overcommitment were similar. High DC and low social support(SS), high ERI and high overcommitment, and high DC and high ERI posed greater risks of depressive symptoms than each of them did alone.ERI model and SS model seem to be effective in estimating the risk of depressive symptoms if they are used respectively. Conclusion The DC had better performance when it was used in combination with low SS. The effect on physical demands was better than on psychological demands. The combination of DCS and ERI models could improve the risk estimate of depressive symptoms in humans.YU Shan Fa NAKATA Akinori GU Gui Zhen SWANSON Naomi G ZHOU Wen Hui HE Li Hua WANG Sheng 2013Biomedical and Environmental Sciences2013,26,12:8
6Determination of aniline in environmental water samples by alternating-current oscillopolarographic titration显示文摘A new method for the determination of aniline in environmental water based on oscillopolarographic titration was presented in this paper. Several factors including the kind, concentration, and volume of acid, the dosage of potassium bromide, the temperature and concentration of concomitant substances were investigated in detail. The experimental results indicated that this method was simple, rapid, and sensitive. The linear range was 8.367×10-4 to 2.789×10-2 mol L-1, the relative standard deviation (R.S.D.) was lower than 0.96%, and the spiked recoveries of aniline in environmental water samples were in the range of 99.4-106.9% under the optimal conditions. The results indicated that the present method could be used as an alternative method for aniline determination in realworld water samples.Jun Ping Xiao Qing Xiang Zhou Xiao Ke Tian Hua Hua Bai Xian Fa Su 2007Chinese Chemical Letters2007,18,6:6
7Effect of Heat Treatment on the Microwave Electromagnetic Properties of Carbonyl Iron/Epoxy-Silicone Resin Coatings显示文摘Microwave absorbing properties of the carbonyl iron particles filled epoxy-silicone resin coatings showed visible degression when the coatings were heat treated at 300 ℃ with different time.The complex permittivity and permeability of the coatings before and after heat treatment were measured.After heat treatment at 300 ℃,the real part of permittivity of the coatings increased with increasing treatment time and showed frequency dependence dielectric response.The complex permeability showed remarkable variation while the resonance frequency of the coatings heat treated at 300 ℃ shifted from 7 to 12 GHz.The electromagnetic results indicated that microwave absorbing properties of the coatings showed more dependent on the complex permeability.The results showed that the difference of the electromagnetic and microwave absorbing properties before and after heat treatment was mainly attributed to the crystalline state transition of carbonyl iron particles.Yuchang Qing,Wancheng Zhou,Shu Jia,Fa Luo and Dongmei Zhu State Key Laboratory of Solidification Processing,Northwestern Polytechnical University,Xi an 710072,China 2010Journal of Materials Science & Technology2010,26,11:6
8Fluorometric determination of nonylphenol in water samples enriched with zirconium doped titanium dioxide nanotubes solid phase extraction显示文摘This paper developed a fluorometric method for the sensitive determination of nonylphenol in water samples by preconcentration with zirconium doped titanium dioxide nanotubes solid phase extraction.The parameters on extraction that would influence the enrichment performance such as the kind and volume of eluent,sample pH,sample flow rate,and sample volume were optimized in detail.Under the optimal conditions,the proposed method provided an excellent linear range of 1-150 mg/L and good LOD of 0.076 mg/L.The relative standard deviation(RSD,n = 6) was 2.8%.Proposed method was also used for the analysis of real water samples and the spiked recoveries were satisfied in the range of 98.7-103%.Xian Fa Su Xin Ning Zhao Guo Hong Xie Qing Xiang Zhou 2012Chinese Chemical Letters2012,23,8:5
9Yttria-stabilized-zirconia hollow spheres prepared by atmospheric plasma spray显示文摘Yttria-stabilizecl-zirconia(YSZ) hollow spheres are widely utilized for their novel physical and chemical properties.However,developing a simple and low-cost method for preparing such hollow spheres still remains a great challenge.In this paper,an atmospheric plasma spray(APS) method is introduced,and the formation mechanism of hollow 7YSZ(ZrO_2-7wt%Y_2O_3) spheres is presented.The hollow sphere morphology was observed by scanning electron microscopy(SEM) when agglomerated and sintered 7YSZ powders were used.Additionally,additive composition changes,phase transformations,and the thermal behavior of 7YSZ powders were analyzed by energy dispersive spectroscopy(EDS),X-ray diffractometry(XRD),thermogravimetric analysis(TG) and differential scanning calorimeter analysis(DSC).Furthermore,the phase transformations of agglomerated and sintered 7YSZ powders,7YSZ hollow spheres that annealed at various temperatures for different times are analyzed.Xiaofeng Zhang Kesong Zhou Fa Chang Chen Song Chunming Deng Siyuan Liang 2014Particuology2014,12,3:4
10Effect and mechanism of acute graft versus host disease on early diffuse murine lung injury following allogeneic stem cell transplantation显示文摘To explore the effect and pathogenssis of acute graft-versus-host disease (aGVHD) on early diffuse lung injury in allogeneic hematopoietic stem cell transplantation (allo-HSCT), we established an aGVHD model of C57BL/6→BALB/c mice. Chest computed tomography (CT) scans, histopathology and the levels of cytokines including tumor necrosis factor α (TNFα) and Interferon (IFNγ) in lungs were dynamically detected in recipient mice after transplantation. The incidence of aGVHD was respectively 0%, 0% and 100% in simple irradiation group (A), syngeneic transplant group(B) and allogeneic transplant group (C). Chest CT scans of recipient mice were normal in 3 groups on days +3 and +7 after transplantation. CT showed that two of ten mice had bilateral lung diffuse infiltrate on day +12 (on the brink of death) in group A and 6 of 10 mice had bilateral lung diffuse infiltrate on day +14 (3 d after aGVHD occurring) in group C, and were normal on days +12 and +14 in group B after transplantation. Histopathology of lungs in the 3 groups was similar, consisting of minor interstitial pneumonitis on day +3. Group A showed edema, hyperplasia of epithelial cells and widened alveolar interval on day +7, and epithelial cell necrosis, lymphocyte infiltration, hemorrhage, protein leakage, and local consolidation on day +12. The histopathology of group B showed slight edema of epithelial cells on +7 day, which were slighter than that on day +3, and virtually normal on day +14. The histopathology in group C was characterized by the significant expansion and congestion of capillaries, and lymphocyte infiltration on day +7, the acute pneumonitis was present involving tissue edema, lymphocyte and macrophage infiltration, protein leakage and perivascular inflammation on day +14. In group A, the levels of TNFα were lower on day +7 than on day +3. In group B, the levels of TNFα attained a peak on day +3, which decreased on days +7 and +14. In group C, the levels of TNFα were highest on day +7 and there was a significant difference between those on days +7 and +14 (P=0.816). In group A, the levels of IFNγ on day +7 were higher than on day +3. In group B, the levels of IFNγ increased progressively, but the comparison of IFNγ levels in different times had no statistical significance (P=0.521, 0.118, 0.340). In group C, the levels of IFNγ attained a peak by day +7 and decreased on day +14. aGVHD is the main cause of early non-infectious lung injury. T lymphocytes and TNFα are possibly implicated in the pathogenesis of acute GVHD-induced lung injury. The decreased levels of IFNγ in lung tissues following transplantation might be associated with pulmonary fibrosis in late non-infectious pulmonary complications.NING Juan, LIU Qi Fa, LUO Xiao Dan, FAN Zhi Ping & Zhang Yu Department of Hematology, Southern Hospital, Southern Medical University, Guang Zhou 510515, China 2009Science China(Life Sciences)2009,52,11:4
11Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia(2021 Edition)显示文摘Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety. In 2018, we issued the guideline “2018 Standard Edition”. However much new direct evidence has now emerged and this may change some of previous recommendations. The time is ripe to develop new evidence-based guidelines, so we formed a working group of clinical experts and methodologists. The steering group members posed 31 questions relevant to the management of TUPKP for BPH covering the following areas: questions relevant to the perioperative period (preoperative, intraoperative, and postoperative) of TUPKP in the treatment of BPH, postoperative complications and the level of surgeons’ surgical skill. We searched the literature for direct evidence on the management of TUPKP for BPH, and assessed its certainty generated recommendations using the grade criteria by the European Association of Urology. Recommendations were either strong or weak, or in the form of an ungraded consensus-based statement. Finally, we issued 36 statements. Among them, 23 carried strong recommendations, and 13 carried weak recommendations for the stated procedure. They covered questions relevant to the aforementioned three areas. The preoperative period for TUPKP in the treatment of BPH included indications and contraindications for TUPKP, precautions for preoperative preparation in patients with renal impairment and urinary tract infection due to urinary retention, and preoperative prophylactic use of antibiotics. Questions relevant to the intraoperative period incorporated surgical operation techniques and prevention and management of bladder explosion. The application to different populations incorporating the efficacy and safety of TUPKP in the treatment of normal volume (< 80 ml) and large-volume (≥ 80 ml) BPH compared with transurethral urethral resection prostate, transurethral plasmakinetic enucleation of prostate and open prostatectomy;the efficacy and safety of TUPKP in high-risk populations and among people taking anticoagulant (antithrombotic) drugs. Questions relevant to the postoperative period incorporated the time and speed of flushing, the time indwelling catheters are needed, principles of postoperative therapeutic use of antibiotics, follow-up time and follow-up content. Questions related to complications incorporated types of complications and their incidence, postoperative leukocyturia, the treatment measures for the perforation and extravasation of the capsule, transurethral resection syndrome, postoperative bleeding, urinary catheter blockage, bladder spasm, overactive bladder, urinary incontinence, urethral stricture, rectal injury during surgery, postoperative erectile dysfunction and retrograde ejaculation. Final questions were related to surgeons’ skills when performing TUPKP for the treatment of BPH. We hope these recommendations can help support healthcare workers caring for patients having TUPKP for the treatment of BPH.Xian-Tao Zeng Ying-Hui Jin Tong-Zu Liu Fang-Ming Chen De-Gang Ding Meng Fu Xin-Quan Gu Bang-Min Han Xing Huang Zhi Hou Wan-Li Hu Xin-Li Kang Gong-Hui Li Jian-Xing Li Pei-Jun Li Chao-Zhao Liang Xiu-Heng Liu Zhi-Yu Liu Chun-Xiao Liu Jiu-Min Liu Guang-Heng Luo Yi Luo Wei-Jun Qin Jian-Hong Qiu Jian-Xin Qiu Xue-Jun Shang Ben-Kang Shi Fa Sun Guo-Xiang Tian Ye Tian Feng Wang Feng Wang Yin-Huai Wang Yu-Jie Wang Zhi-Ping Wang Zhong Wang Qiang Wei Min-Hui Xiao Wan-Hai Xu Fa-Xian Yi Chao-Yang Zhu Qian-Yuan Zhuang Li-Qun Zhou Xiao-Feng Zou Nian-Zeng Xing Da-Lin He Xing-Huan Wang 2022Military Medical Research2022,9,5:4
12Vegetable and Fruit Consumption among Chinese Adults and Associated Factors: A Nationally Representative Study of 170,847 Adults显示文摘Objective This study examined vegetable and fruit(VF) consumption rate and its associated factors among Chinese adults.Methods Nationally representative data from the 2013 China Chronic Disease Surveillance survey were used. Dietary intake data, including VF consumption during the last 12 months, were collected. All analyses were weighted to obtain nationally representative estimates. Associations between VF consumption and other factors(e.g., meal frequency and physical activity) were examined through logistic regression analysis.Results The average fruit consumption was 102.3 g/day(95% CI: 97.0‐107.6) and the average vegetable consumption was 350.6 g/day(95% CI: 339.3‐361.8). Over half(53.2%, 95% CI: 50.9‐55.4) of Chinese adults met the VF consumption of 400 g/day recommended by the World Health Organization(WHO). Rural residents had a higher prevalence of low VF consumption rate than urban residents[49.20%(95% CI: 46.2%‐52.2%) vs. 44.0%(95% CI: 41.7%‐46.3%) P < 0.01]. Old age(OR = 1.01, 95% CI:1.00‐1.01), low educational level, low income, minority ethnicity(OR = 1.41, 95% CI: 1.15‐1.74),underweight(OR = 1.17, 95% CI: 1.03‐1.33), single marital status(OR = 1.20, 95% CI: 1.08‐1.33), low health literacy, irregular breakfast(OR = 1.20, 95% CI: 1.04‐1.38) or lunch(OR = 1.58, 95% CI: 1.26‐1.99)habits, and no leisure‐time physical activity were associated with low VF consumption.Conclusion Only half of Chinese adults met the VF consumption recommended by the WHO. Low socio‐economic status, irregular diet, and poor health literacy were likely associated with low VF consumption. National efforts and programs are needed to promote VF consumption.LI Yi Chong JIANG Bo ZHANG Mei HUANG Zheng Jing DENG Qian ZHOU Mai Geng ZHAO Zhen Ping WANG You Fa WANG Li Min 2017Biomedical and Environmental Sciences2017,30,12:3
13Dielectric Properties of Porous Reaction-boned Si_3N_4 Ceramics with Controlled Porosity and Pore Size显示文摘这篇论文论述反应的微波电介质性质有变体孔和毛孔的结合的多孔的氮化矽陶艺缩放粉末,它被增加形成毛孔的代理人谷物进硅准备。绝缘的常数和样品的绝缘的损失与在样品增加孔显然减少的试验性的结果表演。当孔是不变的时,当毛孔尺寸增加,绝缘的常数和陶艺的绝缘的损失显然减少。在所有获得的样品之中,最小的绝缘的常数是大约 2.4。Jie XU Dongmei ZHU Fa LUO Wancheng ZHOU Peng LI 2008Journal of Materials Science & Technology2008,24,2:3
14Synthesis and Properties of Novel Cationic Maleic Diester Polymerizable Surfactants显示文摘Three new cationic polymerizable surfactants are synthesized by the reaction of alkylmaleic hemiester with glycidyltrimethylammonium chloride. Their structures are confirmed by 1H NMR, IR and elements analysis. The values of CMC and (CMC of these surfactants have been measured. One can obtain nearly monodisperse polystyrene latex by emulsion polymerization using the polymerizable surfactant.Jian XU, Gan Zuo LI*, Guo Wei ZHOU, Fa Ye YAO Key Laboratory for Colloid and Interface Chemistry of State Education Ministry, Shandong University, Jinan 250100 2001Chinese Chemical Letters2001,12,6:3
15Atmospheric emission characterization of a novel sludge drying and co-combustion system显示文摘A novel system combining sludge drying and co-combustion with coal was applied in disposing sludge and its atmospheric emission characteristics were tested. The system was composed of a hollow blade paddle dryer, a thermal drying exhaust gas control system,a 75 tons/hr circulating fluidized bed and a flue gas cleaning system. The emissions of NH3, SO2, CH4and some other pollutants released from thermal drying, and pollutants such as NOx, SO2etc. discharged by the incinerator, were all tested. Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans(PCDD/Fs) in the flue gas from the incinerator were investigated as well. The results indicated that the concentrations of NOx and SO2in the flue gas from the incinerator were 145 and 16 mg/m3, respectively,and the I-TEQ concentration of 2,3,7,8-substitued PCDD/Fs was 0.023 ng I-TEQ/Nm3. All these values were greatly lower than the emission standards of China. In addition, there was no obvious odor in the air around the sludge dryer. The results demonstrated that this drying and co-combustion system is efcient in controlling pollutants and is a feasible way for large-scale treatment of industrial sludge and sewage sludge.Shengyong Lu Liqin Yang Fa Zhou Fei Wang Jianhua Yan Xiaodong Li Yong Chi Kefa Cen 2013Journal of Environmental Sciences2013,25,10:3
16Preparation and Dielectric Properties of Nonstoichiometric β-SiC Powder by Combustion Synthesis显示文摘The nonstoichiometric β-SiC powders were synthesized via combustion reaction of Si and C system in a 0.1 MPa nitrogen atmosphere, using Teflon as the chemical activator. The prepared powders were invistigated by XRD and Raman spectra. The results indicates that the cell parameters of all the prepared β-SiC powder are smaller than the standard value of β-SiC because of generation of CSi defects. The complex permittivity of prepared products was carried out in the frequency range of 8.2-12.4 GHz. It shows that the dielectric property of prepared β-SiC powder decrease with increasing PTFE content. The effect of CSi defects on dielectric property of β-SiC powder has been discussed.Xiaolei Su Wancheng Zhou Zhimin Li Fa Luo Dongmei Zhu 2009Journal of Materials Science & Technology2009,25,3:2
17Impacts of Typhoon ‘Koppu' on Infectious Diarrhea in Guangdong Province,China显示文摘This study aims to quantify the impact of typhoon ‘Koppu’ on infectious diarrhea in Guangdong, China in 2009. Rate ratios (RRs) were calculated by comparing person-time of infectious diarrhea cases between typhoon period and reference period. RRs of dysentery and other infectious diarrhea increased to a maximum of 1.12 (95% CI, 0.86-1.47), 1.10 (95% CI, 1.00-1.20) on the fifth lag day respectively. Children under 5 years were more vulnerable to infectious diarrhea, especially to other infectious diarrhea [RR: 1.21 (1.07-1.36) Vs. 1.03 (0.89-1.82)] after typhoon compared with people aged 〉5 years when RRs were at maximum. A mildly increased risk of infectious diarrhea was not only observed in great damaged regions, but also in other areas.WANG Wei XUN Huan Miao ZHOU Mai Geng JIANG Bao Fa WANG Song Wang GUO Qing KANG Rui Hua WANG Xin Marley Gifty MA Wei 2015Biomedical and Environmental Sciences2015,28,12:2
18Microwave electromagnetic properties of carbonyl iron particles and Si/C/N nano-powder filled epoxy-silicone coating显示文摘Yuchang Qing Wancheng Zhou Fa Luo Dongmei Zhu 2009Physica B: Physics of Condensed Matter2009,,4:1
19Spatial patterns and climate drivers of carbon fluxes in terrestrial ecosystems of China显示文摘Gui‐Rui Yu Xian‐Jin Zhu Yu‐Ling Fu Hong‐Lin He Qiu‐Feng Wang Xue‐Fa Wen Xuan‐Ran Li Lei‐Ming Zhang Li Zhang Wen Su Sheng‐Gong Li Xiao‐Min Sun Yi‐Ping Zhang Jun‐Hui Zhang Jun‐Hua Yan Hui‐Min Wang Guang‐Sheng Zhou Bing‐Rui Jia Wen‐Hua Xiang Ying‐Nian Li Lia 2012Glob Change Biol2012,,3:1
20Epidemiological Survey of Hemoglobinopathies Based on Next-Generation Sequencing Platform in Hunan Province,China显示文摘Objective This study was aimed at investigating the carrier rate of,and molecular variation in,α-andβ-globin gene mutations in Hunan Province.Methods We recruited 25,946 individuals attending premarital screening from 42 districts and counties in all 14 cities of Hunan Province.Hematological screening was performed,and molecular parameters were assessed.Results The overall carrier rate of thalassemia was 7.1%,including 4.83%forα-thalassemia,2.15%forβ-thalassemia,and 0.12%for bothα-andβ-thalassemia.The highest carrier rate of thalassemia was in Yongzhou(14.57%).The most abundant genotype ofα-thalassemia andβ-thalassemia was-α^(3.7)/αα(50.23%)andβ^(IVS-Ⅱ-654)/β^(N)(28.23%),respectively.Fourα-globin mutations[CD108(ACC>AAC),CAP+29(G>C),Hb Agrinio and Hb Cervantes]and sixβ-globin mutations[CAP+8(C>T),IVS-Ⅱ-848(C>T),-56(G>C),beta nt-77(G>C),codon 20/21(-TGGA)and Hb Knossos]had not previously been identified in China.Furthermore,this study provides the first report of the carrier rates of abnormal hemoglobin variants andα-globin triplication in Hunan Province,which were 0.49%and 1.99%,respectively.Conclusion Our study demonstrates the high complexity and diversity of thalassemia gene mutations in the Hunan population.The results should facilitate genetic counselling and the prevention of severe thalassemia in this region.XI Hui LIU Qin XIE Dong Hua ZHOU Xu TANG Wang Lan TANG De Guo ZENG Chun Yan WANG Qiong NIE Xing Hui PENG Jin Ping GAO Xiao Ya WU Hong Liang ZHANG Hao Qing QIU Li FENG Zong Hui WANG Shu Yuan ZHOU Shu Xiang HE Jun ZHOU Shi Hao ZHOU Fa Qun ZHENG Jun Qing WANG Shun Yao CHEN Shi Ping ZHENG Zhi Fen MA Xiao Yuan FANG Jun Qun LIANG Chang Biao WANG Hua 2023Biomedical and Environmental Sciences2023,36,2:1
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