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| 1 | Phase I study of chimeric antigen receptor modified T cells in treating HER2-positive advanced biliary tract cancers and pancreatic cancers显示文摘 | Kaichao Feng Yang Liu Yelei Guo Jingdan Qiu Zhiqiang Wu Hanren Dai Qingming Yang Yao Wang Weidong Han1,3 | 2018 | Protein & Cell2018，9，10： | 37 |
| 2 | Secondary organic carbon quantification and source apportionment of PM_(10) in Kaifeng, China显示文摘During 2005, the filter samples of ambient PM10 from five sites and the source samples of particulate matter were collected in Kaifeng, Henan Province of China. Nineteen elements, water-soluble ions, total carbon (TC) and organic carbon (OC) contained in samples were analyzed. Seven contributive source types were identified and their contributions to ambient PM10 were estimated by chemical mass balance (CMB) receptor model. Weak associations between the concentrations of organic carbon and element carbon (EC) were observed during the sampling periods, indicating that there was secondary organic aerosol pollution in the urban atmosphere. An indirect method of 'OC/EC minimum ratio' was applied to estimate the concentration of secondary organic carbon (SOC). The results showed that SOC contributed 26.2%, 32.4% and 18.0% of TC in spring, summer-fall and winter, respectively, and the annual average SOC concentration was 7.07 μg/m3, accounting for 5.73% of the total mass in ambient PM10. The carbon species concentrations in ambient PM10 were recalculated by subtracting SOC concentrations from measured concentrations of TC and OC to increase the compatibility of source and receptor measurements for CMB model. | WU Lin FENG Yinchang WU Jianhui ZHU Tan BI Xiaohui HAN Bo YANG Weihong YANG Zhiqiang | 2009 | Journal of Environmental Sciences2009，21，10： | 26 |
| 3 | Discovery of Late Cretaceous foraminifera in the Songliao Basin: Evidence from SK-1 and implications for identifying seawater incursions显示文摘The Songliao Basin is the largest oil-bearing basin in China.In the absence of sufficient evidence,the possibility of seawater incursion(s) into the Songliao Basin remains controversial.Recently,we discovered relatively abundant foraminifera fossils from units 1 and 2 of the Nenjiang Formation of borehole SK-1.Benthic foraminifera (Gavlinella sp.,Anomalinoides sp.,Pullenia sp.,Haplophragmoides sp.,Karrorulina hokkaidoana,Clavulinoides sp.),as well as planktonic foraminifera (Archaeoglobigerina blowi,Archaeoglobigerina cretacea and Hedbergella flandrini),were identified.These fossils were widely distributed in the marine Cretaceous.According to the global distribution of the above-mentioned planktonic foraminifera,the age of these fossil bearing strata appears to be Late Coniacian to Santonian.More importantly,these foraminifera provide direct evidence for marine water incursions into the Songliao Basin during deposition of the Lower Nenjiang Formation. | XI DangPeng WAN XiaoQiao FENG ZhiQiang LI Shun FENG ZiHui JIA JianZhong JING Xia SI WeiMin | 2011 | Chinese Science Bulletin2011，56，3： | 21 |
| 4 | The Deep-Time Digital Earth program:data-driven discovery in geosciences显示文摘Current barriers hindering data-driven discoveries in deep-time Earth(DE)include:substantial volumes of DE data are not digitized;many DE databases do not adhere to FAIR(findable,accessible,interoperable and reusable)principles;we lack a systematic knowledge graph for DE;existing DE databases are geographically heterogeneous;a significant fraction of DE data is not in open-access formats;tailored tools are needed.These challenges motivate the Deep-Time Digital Earth(DDE)program initiated by the International Union of Geological Sciences and developed in cooperation with national geological surveys,professional associations,academic institutions and scientists around the world.DDE’s mission is to build on previous research to develop a systematic DE knowledge graph,a FAIR data infrastructure that links existing databases and makes dark data visible,and tailored tools for DE data,which are universally accessible.DDE aims to harmonize DE data,share global geoscience knowledge and facilitate data-driven discovery in the understanding of Earth’s evolution. | Chengshan Wang Robert MHazen Qiuming Cheng Michael HStephenson Chenghu Zhou Peter Fox Shu-zhong Shen Roland Oberhansli Zengqian Hou Xiaogang Ma Zhiqiang Feng Junxuan Fan Chao Ma Xiumian Hu Bin Luo Juanle Wang Craig M.Schiffries | 2021 | National Science Review2021，8，9： | 14 |
| 5 | Long Distance Transmission of SARS-CoV-2 from Contaminated Cold Chain Products to Humans——Qingdao City,Shandong Province,China,September 2020显示文摘Summary What is already known about this topic?Though coronavirus disease 2019(COVID-19)has largely been controlled in China,several outbreaks of COVID-19 have occurred from importation of cases or of suspected virus-contaminated products.Though several outbreaks have been traced to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)isolated on the outer packaging of cold chain products,live virus has not been obtained. | Huilai Ma Zhaoguo Wang Xiang Zhao Jun Han Yong Zhang Hong Wang Cao Chen Ji Wang Fachun Jiang Jie Lei Jingdong Song Shaofeng Jiang Shuangli Zhu Huihui Liu Dongyan Wang Yao Meng Naiying Mao Yanhai Wang Zhen Zhu Zhixiao Chen Bingling Wang Qinqin Song Haijun Du Qun Yuan Dong Xia Zhiqiang Xia Peipei Liu Yuchao Wu Zijian Feng Ruqin Gao George F.Gao Wenbo Xu | 2021 | China CDC weekly2021，3，30： | 13 |
| 6 | Zebrafish model for assessing induced organ toxicity by Strychnos nux-vomica显示文摘OBJECTIVE:To assess the acute organ toxicity of Strychnos nux-vomica with zebrafish model visually.METHODS:To assess acute toxicity,we initially determined the lethal concentration after Strychnos nux-vomica treatment for 24 h.Zebrafish was treated with five concentrations Strychnos nux-≦vo LC10 for 24 h,and the effects ofmica on morphology,function of heart,central nervous system,liver,kidney and organ-specific cell death were assessed.Next,we assessed the reversibility of toxic effect.RESULTS:Strychnos nux-vomica has an effect on the different organs of zebrafish,including heart,central nervous system,liver,and kidney,and cadiotoxicity induced by Strychnos nux-vomica was reversible to some extent.CONCLUSION:Zebrafish model is suitable for confirming the toxic target organs for Chinese traditional medicine. | Zhao Chongjun Tian Jinghuan Wang Jinfeng Feng Yaru Ni Yuanyuan Fan Jiaojiao Wang Chunmei Cao Dan Zou Qinwen Ma Zhiqiang Lin Ruichao | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 9 |
| 7 | Dynamic-statistics combined forecast scheme based on the abrupt decadal change component of summer precipitation in East Asia显示文摘基于 19832011 CMAP 数据,在东亚的降水异例和它的附近的海区域(此后叫的东亚为短) 在 1999 前表明 ++ 模式并且 + 模式以后;这个十的变化在相应 EOF3 部件主要被包含。然而, NCC_CGCM 预报结果是相当不同的,它在 1999 前揭示 ++ 模式并且 ++ 模式以后。同时,基于这些关键 SST 区域改进 NCC_CGCMs 预报精确性的概率被讨论,并且动态统计的联合预报计划为增加在东亚在夏天降水包含的十的变化的信息被构造。独立样品预报结果显示这个预报计划罐头有效地修改十的变化信息在东亚在夏天降水包含了的 NCC_CGCMs (特别在 30 敢琠敨攠癮 的区域吗?? | GONG ZhiQiang ZHAO JunHu FENG GuoLin CHOU JiFan | 2015 | Science China Earth Sciences2015，58，3： | 7 |
| 8 | Discovery of “Enveloping Surface of Oil and Gas Overpressure Migration” in the Songliao Basin and its bearings on hydrocarbon migration and accumulation mechanisms显示文摘The Fuyang oil layer of the Songliao Basin is a tight and low-permeability sandstone pay zone formed in the fluvial-shallow water delta environment.In the formation are mainly lithologic reservoir and tight reservoir.The lacustrine-mudstone of K2qn1 is a good source rock and also acts as a good regional cap rock.The Fuyang oil layer is a typical upper-source and lower-reservoir pattern distributed in a large area.Based on a large number of exploration and development data, a macroscopic enveloping surface is found developed in the Fuyang oil layer, which is below K2qn1.The effective reservoirs within the enveloping surface are commonly saturated with oil, and below the enveloping surface are mainly water layers.The distance from the enveloping surface to the bottom of the source rock is usually 100-350 m and at most 550 m.Through the research of the distribution patterns and the physical properties of the sandbodies above or beneath the source rock, it is concluded that: 1) the enveloping surface is the boundary of the overpressure hydrocarbon migration; 2) the spacial distribution of the pressure release beds controls the direction and the distance of the overpressure hydrocarbon migration; 3) tight oil reservoirs and lenticular oil reservoirs are mainly formed inside the envelope surface, whereas, conventional reservoirs are formed outside the envelope surface as a result of the buoyancy hydrocarbon migration.The discovery of the 'overpressure hydrocarbon migration enveloping surface' and the concepts of overpressure hydrocarbon migration and buoyancy hydrocarbon migration not only challenge the old notion that 'hydrocarbon migrates along the faults and is distributed along fault belts' in the Fuyang oil layer of the Songliao Basin, give a new explanation to the long-distance-oil-downwards migration (hundreds of meters) and expand the exploration potential of the Fuyang oil layer, and provide a rational guidance to the exploration of syncline plays, but also better categorize tight oil/gas and conventional reservoirs in all of the key elements related to hydrocarbon migration, accumulation, reservoir characteristics and oil and gas spatial distribution. | FENG ZhiQiang ZHANG Shun FENG ZiHui | 2012 | Science China Earth Sciences2012，55，12： | 6 |
| 9 | Rapid Assessment on Potential Risks of Schistosomiasis Transmission—7 PLADs,China,2019 and 2021显示文摘Summary What is already known about this topic?Oncomelania hupensis(O.hupensis)and livestock are main infection sources of schistosomiasis.The schistosome infected O.hupensis and livestock’s feces are important risk factors in the transmission of schistosomiasis.What is added by this report?The potential risks of schistosomiasis transmission remain prevalent,giving an early warning to local government with information on existing transmission risks.It is expected that the effectiveness and efficiency of schistosomiasis surveillance could be improved by conducting rapid risk assessment at the beginning of transmission season. | Junyi He Hongqing Zhu Ziping Bao Lijuan Zhang Yinlong Li Ting Feng Suying Guo Wangping Deng Can Wang Hui Dang Tiewu Jia Chao Lyu Zhiqiang Qin Chunli Cao Jing Xu Shizhu Li Xiaonong Zhou | 2021 | China CDC weekly2021，3，51： | 5 |
| 10 | Additive manufacturing alumina components with lattice structures by digital light processing technique显示文摘Digital light processing technique was applied to manufacture alumina ceramic parts with two types of lattice structure units, i.e. vertex interconnect structure and edge structure. The internal porosity of the unit is 40%. The printed parts were sintered and the grain size is about 1.1 μm. The bending strength of the vertex interconnect structure is much larger than that of the edge structure. Materials genome initiative(MGI) aims to digital design and intelligent manufacture for advanced components. This research shows us an example to achieve this goal. | Qjngfeng Zeng Changhao Yang Dingyi Tang Jiayao Li Zhiqiang Feng Jiantao Liu Kang Guan | 2019 | Journal of Materials Science & Technology2019，35，12： | 5 |
| 11 | Numerical Simulation for Accuracy of Velocity Analysis in Small-Scale High-Resolution Marine Multichannel Seismic Technology显示文摘When used with large energy sparkers, marine multichannel small-scale high-resolution seismic detection technology has a high resolution, high-detection precision, a wide applicable range, and is very flexible. Positive results have been achieved in submarine geological research, particularly in the investigation of marine gas hydrates. However, the amount of traveltime difference information is reduced for the velocity analysis under conditions of a shorter spread length, thus leading to poorer focusing of the velocity spectrum energy group and a lower accuracy of the velocity analysis. It is thus currently debatable whether the velocity analysis accuracy of short-arrangement multichannel seismic detection technology is able to meet the requirements of practical application in natural gas hydrate exploration. Therefore, in this study the bottom boundary of gas hydrates(Bottom Simulating Reflector, BSR) is used to conduct numerical simulation to discuss the accuracy of the velocity analysis related to such technology. Results show that a higher dominant frequency and smaller sampling interval are not only able to improve the seismic resolution, but they also compensate for the defects of the short-arrangement, thereby improving the accuracy of the velocity analysis. In conclusion, the accuracy of the velocity analysis in this small-scale, high-resolution, multi-channel seismic detection technology meets the requirements of natural gas hydrate exploration. | LUO Di CAI Feng WU Zhiqiang | 2017 | Journal of Ocean University of China2017，16，3： | 5 |
| 12 | Concentration quenching in transparent glass ceramics containing Er^(3+):NaYF_4 nanocrystals显示文摘In this work, we have studied the concentration quenching in transparent glass ceramics containing Er3+:NaYF4 nanocrystals. For different concentrations, the emission spectra and decay curves of the 4I13/2→4I15/2 emission were measured. The Er-concentration dependence of integrated intensity and lifetime of 4I13/2→4I15/2 emission are showed. With the increase of the Er3+ doping concentration, the 1.5 m fluorescence emission first increases, then decreases, and the lifetime falls gradually. With 980 nm excitation, the efficiency of the energy transfer from Er3+ to quenching centers reaches 73.73% for the sample with 4 mol% Er3+. Meanwhile, owing to the relation of fluorescence integrated intensity and Er-concentration, a dipole-dipole quenching mechanism in the framework of a limited diffusion regime has been proved. Using the limited diffusion case, the critical concentration for quenching has been determined from a fitting equation of the lifetime and Er-concentration. The fitting result shows the critical concentration for quenching is higher than the values obtained in Er-doped different glass by an order of magnitude. | HUANG XingYong CHEN DaQin LIN Lin WANG ZheZhe WANG YuanSheng FENG ZhuoHong ZHENG ZhiQiang | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，7： | 5 |
| 13 | Perioperative factors related to prognosis of regular hepatectomy in comparison with irregular hepatectomy显示文摘 | Feng Zhiqiang Li Hongqi Zhang Jinqian Xu Lining Xiao Mei Huang Zhiqiang Zhang Hongyi | 2014 | Chinese Medical Journal2014，，2： | 4 |
| 14 | Natural gas consumption forecasting model based on coal-to-gas project in China显示文摘Natural gas is widely used because it is environmentally friendly,particularly in reducing carbon emission and improving the Air Quality Index(AQI)around densely populated cities.China has initiated a coal-to-gas project(CGP)to improve the air quality in northern China.As a subcompany of China National Petroleum Corporation,PetroChina Natural Gas Marketing North Company has been focusing on natural gas resource allocation while considering numerous issues such as ensuring the bottom line of livelihood requirements in winter and the performance of economic indicators for an entire calendar year in the northern part of China.Therefore,the accurate prediction of natural gas consumption is important to PetroChina Natural Gas Marketing North Company.It has become a challenge to forecast natural gas consumption because the natural gas market has changed considerably because of the CGP.Natural gas consumption cannot be forecasted using conventional models.This study analyzes the characteristics of the CGP based on the data obtained from rural individual users and company users.Based on the analysis,the gas consumption in winter is predicted using two different forecasting approaches.The methods presented in this paper provide a basis for formulating effective measures for natural gas scheduling in the northern part of China. | Zhiqiang Wang Yichen Li Zhanjun Feng Kai Wen | 2019 | Global Energy Interconnection2019，2，5： | 4 |
| 15 | Extractive Desulfurization from Simulated Sulfur-Rich Naphtha显示文摘Upon extractive desulfurization of sulfur-rich oil obtained after recycling raffinate,the effects of single and compound extractants,temperature,and extractant/oil ratio on desulfurization rate,oil loss rate,extractant loss rate,and selectivity coefficient were investigated.The results showed that the thiophene existing in the simulated sulfur-rich oil could be further removed by extraction.The single-stage desulfurization rates achieved by dimethyl sulfoxide(DMSO)and sulfolane(SF)were 53.51%and 47.36%,respectively,while the selectivity coefficient of SF was 1.13,which was higher than that of DMSO(with a selectivity coefficient of 1.04).For the compound extractant,a single-stage desulfurization rate of 49.59%and a selectivity coefficient of 1.40 were obtained by using DMSO+10%MEA as the extractant,which was higher than that of SF.Upon using 50%SF+50%DMSO as the extractant,the single-stage desulfurization rate reached 50.92%with a selectivity coefficient of 1.32.Based on the comprehensive consideration,the DMSO+10%MEA extractant was selected as the best extractant for treating the sulfur-rich oil. | Shen Xizhou Li Zhiqiang Fang Liuya Song Hao Gan Feng Shen Zhi | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，3： | 4 |
| 16 | Effect of electrode Pt-loading and cathode flow-field plate type on the degradation of PEMFC显示文摘The electrode Pt-loading has an effect on the number of active sites and the thickness of catalyst layer,which has huge influence on the mass transfer and water management during dynamic process in PEMFCs. In this study, membrane electrode assemblies with different Pt-loadings were prepared, and PEMFCs were assembled using those membrane electrode assemblies with traditional solid plate and water transport plate as cathode flow-field plates, respectively. The performance and electrochemical surface area of cells were characterized to evaluate the membrane electrode assemblies degradation after rapid currentvariation cycles. Scanning electron microscope and transmission electron microscope were used to investigate the decay of catalyst layers and Pt/C catalyst. With the increase of Pt-loading, the performance degradation of membrane electrode assemblies will be mitigated. But higher Pt-loading means thicker catalyst layer, which leads to a longer pathway of mass transfer, and it may result in carbon material corrosion in membrane electrode assemblies. The decay of Pt/C catalyst in cathode is mainly caused by the corrosion of carbon support, and the degradation of anode Pt/C catalyst is a consequence of migration and aggregation of Pt particles. And using water transport plate is beneficial to alleviating the age of cathode Pt/C catalyst. | Lijuan Qu Zhiqiang Wang Xiaoqian Guo Wei Song Feng Xie Liang He Zhigang Shao Baolian Yi | 2019 | Journal of Energy Chemistry2019，28，8： | 4 |
| 17 | Geoscience knowledge graph in the big data era显示文摘Since the beginning of the 21 st century,the geoscience research has been entering a significant transitional period with the establishment of a new knowledge system as the core and with the drive of big data as the means.It is a revolutionary leap in the research of geoscience knowledge discovery from the traditional encyclopedic discipline knowledge system to the computer-understandable and operable knowledge graph.Based on adopting the graph pattern of general knowledge representation,the geoscience knowledge graph expands the unique spatiotemporal features to the Geoscience knowledge,and integrates geoscience knowledge elements,such as map,text,and number,to establish an all-domain geoscience knowledge representation model.A federated,crowd intelligence-based collaborative method of constructing the geoscience knowledge graph is developed here,which realizes the construction of high-quality professional knowledge graph in collaboration with global geo-scientists.We also develop a method for constructing a dynamic knowledge graph of multi-modal geoscience data based on in-depth text analysis,which extracts geoscience knowledge from massive geoscience literature to construct the latest and most complete dynamic geoscience knowledge graph.A comprehensive and systematic geoscience knowledge graph can not only deepen the existing geoscience big data analysis,but also advance the construction of the high-precision geological time scale driven by big data,the compilation of intelligent maps driven by rules and data,and the geoscience knowledge evolution and reasoning analysis,among others.It will further expand the new directions of geoscience research driven by both data and knowledge,break new ground where geoscience,information science,and data science converge,realize the original innovation of the geoscience research and achieve major theoretical breakthroughs in the spatiotemporal big data research. | Chenghu ZHOU Hua WANG Chengshan WANG Zengqian HOU Zhiming ZHENG Shuzhong SHEN Qiuming CHENG Zhiqiang FENG Xinbing WANG Hairong LV Junxuan FAN Xiumian HU Mingcai HOU Yunqiang ZHU | 2021 | Science China Earth Sciences2021，64，7： | 4 |
| 18 | Preparation and particle size characterization of Cu nanoparticles prepared by anodic arc plasma显示文摘Copper nanoparticles were successfully prepared in large scale by means of anodic arc discharging plasma method in inert atmosphere. The particle size, specific surface area, crystal structure, and morphology of the samples were characterized by X-ray diffraction (XRD), BET equation, transmission electron microscopy (TEM), and the corresponding selected area electron diffraction (SAED). The experimental results indicate that the crystal structure of the samples is fcc structure the same as that of the bulk materials. The specific surface area is 11 m2/g, the particle size distribution is 30 to 90 nm, and the average particle size is about 67 nm obtained from TEM and confirmed from XRD and BET results. The nanoparticles with uniform size, high purity, narrow size distribution and spherical shape can be prepared by this convenient and effective method. | WEI Zhiqiang XIA Tiandong FENG Wangjun DAI Jianfeng WANG Qing LI Weixue YAN Pengxun | 2006 | Rare Metals2006，25，2： | 4 |
| 19 | Advances in diagnosis and non-surgical treatment of Bell's palsy显示文摘Bell's palsy is a commonly seen cranial nerve disease and can result in compromised facial appearance and functions. Its etiology, prognosis and treatment are still being debated. This paper is a review of recent development in the understanding of etiology, diagnosis and non-surgical treatment of Bell's palsy. | Yang Zhao Guodong Feng Zhiqiang Gao | 2015 | Journal of Otology2015，10，1： | 3 |
| 20 | Phase Ⅲ Clinical Trials of the Cell Differentiation Agent-2 (CDA-2): Therapeutic Efficacy on Breast Cancer, Non-Small Cell Lung Cancer and Primary Hepatoma显示文摘 | Fengyi Feng Qing Lu Changquan Ling Yang Zhang Fengzhan Qin Huaqing Wang Wenxia Huang Shunchang Jiao Qiang Chen Mingzhong Li Yunzhong Zhu Meizhen Zhou Jun Ren Yetao Gao Jingpo Zhao Rongsheng Zheng Wenhua Zhao Zhiqiang Meng Fang Li Qizhong Zhang Dongli Zhao Liyan Xu Yongqiang Zhang Yanjun Zhang Zhenjiu Wang Shuonqi Liu Ming C. Liau | 2005 | Chinese Journal of Clinical Oncology2005，2，4： | 3 |
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