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| 1 | Coopetition and product innovation performance: the role of internal knowledge sharing mechanisms and formal knowledge protection mechanisms 显示文摘 | ESTRADA I FAEMS D DE FARIA P | 2015 | Industrial Marketing Man- agement2015，53，2： | 1 |
| 2 | Visual and flight performance recovery after PRK or LASIK in helicopter pilots显示文摘 | Van de Pol C Greig JL Estrada A | | 0，，6： | 1 |
| 3 | Physical Activity Assessment in Adults显示文摘 | Estrada Bonilla YC Garavito FR Gonzdlez de Ios Reyes Y | 2015 | Medicine & Science in Sports & Exercise2015，47，5： | 1 |
| 4 | Visual and fight per for mance recover y af ter PR K or LASI K in helicopter pilots显示文摘 | Van de Pol C Greig JL Estrada A | 2007 | Aviat Space Environ Med2007，78，6： | 1 |
| 5 | Carbaz- de-based cyano-stilbene highly fluorescent microcrys- tats显示文摘 | Upamall K A N Estrada L A De P K et 01 | 2011 | Langrauir2011，27，5： | 1 |
| 6 | Clinicopathological differences,risk factors and prognostic scores for western patients with intestinal and diffuse-type gastric cancer显示文摘BACKGROUND In the molecular era,the Laurén system is still a cost-effective and widely implemented classification for gastric cancer(GC)and it has been recently associated with clinical,histological and molecular features of these tumors.Despite recent advances in the understanding of the molecular biology of GC,there is a need to develop new prognostic tools for patient stratification in clinical practice.Thus,the identification of easily available prognostic factors in patients with intestinal and diffuse-type tumors can significantly improve risk assessment and patient stratification in GC.AIM To identify clinicopathological differences,risk factors,and to develop costeffective prognostic scores for patients with intestinal and diffuse-type GC.METHODS Retrospective study of all patients undergoing surgery for GC at a tertiary referral center from 2001 to 2019.286 cases met inclusion criteria(intestinal:190,diffuse:96).Clinical data and gross findings were collected.All specimens were reviewed by two independent pathologists and a detailed protocol for histologic evaluation was followed.Five tissue microarrays(TMAs)were constructed and sections of the TMA block were immunostained for HERCEPTEST,MSH2,MSH6,MLH1 and PMS2.Statistical analyses were performed and prognostic scores were developed based on hazard ratios.RESULTS Intestinal and diffuse-type GC showed different epidemiological,clinicopathological and prognostic features.Diffuse tumors were significantly associated with younger age,less symptomatology,flat morphology,deeper invasion,perineural infiltration,advanced stage at diagnosis,administration of adjuvant therapy and poorer prognosis.Intestinal lesions were fungoid or polypoid,showed necrosis,desmoplasia,microsatellite instability and HERCEPTEST positivity and were diagnosed at earlier stages.Tumor depth,desmoplasia,macroscopic type and lymph node involvement were independently related to the Laurén subtype.Furthermore,intestinal and diffuse GC were associated with different risk factors for progression and death.Vascular invasion,perineural infiltration and growth pattern were important prognostic factors in intestinal-type GC.On the contrary,tumor size and necrosis were significant prognosticators in diffuse-type GC.Our recurrence and cancer-specific death scores for patients with intestinal and diffuse-type GC showed an excellent patient stratification into three(diffuse GC)or four(intestinal)prognostic groups.CONCLUSION Our findings support that Laurén subtypes represent different clinicopathological and biological entities.The development of specific prognostic scores is a useful and cost-effective strategy to improve risk assessment in GC. | Cristina Díaz del Arco Lourdes Estrada Muñoz Luis Ortega Medina Elena Molina Roldán MÁngeles Cerón Nieto Soledad García Gómez de las Heras M Jesús Fernández Aceñero | 2022 | World Journal of Gastrointestinal Oncology2022，14，6： | 1 |
| 7 | Erythropoietin protects the in vitro blood - brain barrier against VEGF - induced permeability显示文摘 | Martinez - Estrada OM Rodriguez - Millan E Gonzalez - De | 2003 | Eur J Neurosci2003，18，： | 1 |
| 8 | Erythropoietin protects the in vitro blood- brain barrier against VEGF- induced permeability 显示文摘 | Martinez- Estrada OM Rodriguez- Millan E de Vicente EG | 2003 | Eur J Neuroc2003，18，： | 1 |
| 9 | Eryth-ropoietin protects the in vitro blood - brain barrier against VEGF - induced permeability 显示文摘 | Martinez - Estrada OM Rodriguez - Millan E Gonzalez - De Vicente E | 2003 | Eur J Neurosci2003，18，： | 1 |
| 10 | Functional mitral regurgitation after a first non-ST segment elevation a- cute coronary syndrome: very-long-term follow-up, prognosis and contribution to left ventrieular enlargement and atrial fib- rillation development显示文摘 | Nnez-Gil I J Estrada I Perez de Isla L | 2013 | Heart2013，99，20： | 1 |
| 11 | Steroid-refractory ulcerative colitis and associated primary sclerosing cholangitis treated with infliximab显示文摘Primary sclerosing cholangitis is an infrequent extraintestinal manifestation of ulcerative colitis.Damage to bile ducts is irreversible and medical therapies to prevent progression of the disease are usually ineffective.We describe a patient with long-standing ulcerative colitis,which was refractory to corticosteroid therapy who developed primary sclerosing cholangitis(biochemical stage Ⅱ/Ⅳ) in the course of his pancolitis.Treatment with infliximab(5 mg/kg as an induction dose followed by maintenance doses every two months) was indicated because of steroid-dependent disease associated to primary sclerosing cholangitis as well as sacroiliitis and uveitis and previous episode of severe azathioprinerelated hepatic toxicity.At present,after two years of follow-up,the patient is asymptomatic with normal liver tests and complete resumption of daily life activities.This case draws attention to the usefulness of antitumor necrosis factor-alpha therapy for the management of primary sclerosing cholangitis as extraintestinal manifestation of inflammatory bowel disease. | Ileana Duca Patricia Ramírez de la Piscina Silvia Estrada Rosario Calderón Katerina Spicakova Leire Urtasun Carlos Marra-López Salvador Zabaleta Raquel Bengoa María Asunción Marcaide Francisco García-Campos | 2013 | World Journal of Gastroenterology2013，19，4： | 1 |
| 12 | Effects of the toxic dinoflagellate, Gymnodinium catenatum on hydrolytic and antioxidant enzymes, in tissues of the giant lions-paw scallop Nodipecten subnodosus显示文摘 | Estrada N de Jest~s Romero M Campa-C6rdova A | 2007 | Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology2007，146，4： | 1 |
| 13 | Erythropoietin protects the in vitro blood brain barrier against VEGF induced permeability显示文摘 | Martinez Estrada OM Rodriguez Millan E Gonzalez De Vicente E | 2003 | Eur J Neurosci2003，18，： | 1 |
| 14 | Growth enhancement in trans-genic tilapia by ectopic expression of tilapia growth hor-mone显示文摘 | Martínez R Estrada M.P Berlanga J Guillén I Hernández O Cabrera E Pimentel R Morales R Herrera F Morales A Pi?a J.C Abad Z Sánchez V Melamed P Lleonart R and de la Fuente J | | 0，，01： | 1 |
| 15 | Visual and flight performance recovery after PRK or LASIK in helicopter pilots显示文摘 | Van de Pol C Greig JL Estrada A | 2007 | Aviat Space Environ Med2007，78，6： | 1 |
| 16 | N-Terminal B-Type Natriuretic Peptide Assessment Provides Incremental Prognostic Information in Patients With Acute Coronary Syndromes and Normal Troponin T Values Upon Admission显示文摘 | Michael Weber Oscar Bazzino Jose L. Navarro Estrada Juan J. Fuselli Fernando Botto Diego Perez de Arenaza Helge M?llmann Holger N. Nef Albrecht Els?sser Christian W. Hamm | 2008 | Journal of the American College of Cardiology2008，，12： | 1 |
| 17 | Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/ thioctic acid: participation of elements of the insulin signaling pathway 显示文摘 | Estrada DE Ewart HS Tsakiridis T | 1996 | Diabetes1996，45，12： | 1 |
| 18 | Improved diagnostic and prognostic performance of a new high-sensitive troponin T assay in patients with acute coronary syndrome显示文摘 | Michael Weber Oscar Bazzino Jose Luis Navarro Estrada Raul de Miguel Simon Salzberg Juan J. Fuselli Christoph Liebetrau Mariella Woelken Helge Moellmann Holger Nef Christian Hamm | 2011 | American Heart Journal2011，，1： | 1 |
| 19 | Visual and flight performance recovery after PRA or LASIK in helicopter pilots 显示文摘 | Van DE Greig JL Estrada A | 2007 | Aviat Space Environ Meal2007，78，6： | 1 |
| 20 | Research and development of the back-end electronics for the two-dimensional improved resistive plate chambers in CMS upgrade显示文摘Purpose To complement and ensure redundancy in the endcap muon system of the Compact Muon Solenoid(CMS)detector and to extend the Resistive Plate Chamber(RPC)system coverage,improved RPCs(iRPCs)with either orthogonal layer strips with one-end electronics or single layer strips with two-end electronics providing more precise time measurement will be installed in the very forward pseudorapidity region of|η|<2.4.The iRPC readout system needs to support twodimensional(2D)or two-end readout.In addition,it must combine detector data with Timing,Trigger and fast Control(TTC)and Slow Control(SC)into one data stream over a bi-directional optical link with a line rate of 4.8 Gb/s between the Front-End Electronics(FEE)and the Back-End Electronics(BEE).To fulfill these requirements,a prototype BEE for the iRPC 2D chamber has been researched and designed.Methods A Micro-Telecommunication and Computing Architecture(μTCA)-based processing card was designed in this study to establish a prototype system together with aμTCA crate.The Giga-Bit Transceiver(GBT)protocol is integrated to provide bi-directional communication between the FEE and BEE.A server is connected with the BEE by a Gigabit Ethernet(GbE)link for SC and a 10-GbE link for Data AcQuisition(DAQ).Results The Bit Error Rate(BER)test of the back-end board and a joint test with the iRPC 2D prototype chamber were performed.ABERof less than 1.331×10−16 was obtained.The timemeasurement with a resolution of 3.05 nswas successfully realized,and detector efficiencies of 97.7%for longitudinal strips and 96.0%for orthogonal strips were measured.Test results demonstrate the correctness and reliability of the prototype BEE.Conclusion The BEE prototype satisfies the requirements for the iRPC 2D chamber,and it worked stably and reliably during a long-term joint test run. | P.Cao Z-A.Liu J.Zhao H.Kou J.Tao J.Song W.Gong N.Wang A.Samalan M.Tytgat N.Zaganidis G.A.Alves F.Marujo F.Torres.Da.S.ilva.De.Araujo E.M.Da Costa D.De Jesus Damiao H.Nogima A.Santoro S.Fonseca De Souza A.Aleksandrov R.Hadjiiska P.Iaydjiev M.Rodozov M.Shopova G.Sultanov M.Bonchev A.Dimitrov L.Litov B.Pavlov P.Petkov A.Petrov S.J.Qian C.Bernal A.Cabrera J.Fraga A.Sarkar S.Elsayed Y.Assran M.El Sawy M.A.Mahmoud Y.Mohammed X.Chen C.Combaret M.Gouzevitch G.Grenier I.Laktineh L.Mirabito K.Shchablo I.Bagaturia D.Lomidze I.Lomidze V.Bhatnagar R.Gupta P.Kumari J.Singh V.Amoozegar B.Boghrati M.Ebraimi R.Ghasemi M.Mohammadi Najafabadi E.Zareian M.Abbrescia R.Aly W.Elmetenawee N.De Filippis A.Gelmi G.Iaselli S.Leszki F.Loddo I.Margjeka G.Pugliese D.Ramos L.Benussi S.Bianco D.Piccolo S.Buontempo A.Di Crescenzo F.Fienga G.De Lellis L.Lista S.Meola P.Paolucci A.Braghieri P.Salvini P.Montagna C.Riccardi P.Vitulo B.Francois T.J.Kim J.Park S.Y.Choi B.Hong K.S.Lee J.Goh H.Lee J.Eysermans C.Uribe Estrada I.Pedraza H.Castilla-Valdez A.Sanchez-Hernandez C.A.Mondragon Herrera D.A.Perez Navarro G.A.Ayala Sanchez S.Carrillo E.Vazquez A.Radi A.Ahmad I.Asghar H.Hoorani S.Muhammad M.A.Shah I.Crotty | 2021 | Radiation Detection Technology and Methods2021，5，2： | 0 |
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