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| 1 | 中国妇女妊娠前后单纯服用叶酸对神经管畸形的预防效果显示文摘目的 评价妇女在妊娠前后服用单纯 40 0 μg叶酸增补剂对胎 /婴儿神经管畸形 (NTDs)的预防效果。方法 1993~ 1995年在中国北方的NTDs高发地区和南方的NTDs低发地区妇女增补叶酸的推广项目中 ,共募集从孕前或孕后任何时间开始服药的妇女 130 142名 ,未服药的妇女 1176 89名 ;设计的服药方法从婚检时开始到孕满 3个月为止 ,每天服用单纯叶酸片 40 0 μg ;最后对妇女的分娩结局进行监测并进行预防效果的对比评价研究。结果 服药组妇女生育的胎婴儿中共发现 10 2例NTDs ,对照组胎婴儿中共发现 173例NTDs。末次月经前募集的未服药妇女在孕 2 0周以后分娩的胎婴中NTDs发生率 ,北方为 4 8‰ (16 / 3 318) ,南方为 1 0‰ (2 8/ 2 82 6 5 ) ,而妊娠前后服药妇女组则分别为1 0‰ (13/ 13 0 12 )和 0 6‰ (34/ 5 86 38)。与末次月经前募集的未服药妇女组相比 ,北方服药妇女NTDs发生率明显降低 ,其中依从性大于 80 %的服药组妇女预防率达 85 % (95 %CI为 6 2 %~ 94% ) ,南方地区服叶酸的预防率为 41% (95 %CI为 3 %~ 6 4% )。结论 妇女在妊娠前后每天服用单纯叶酸 40 0 | 李竹 RobertJ Berry 李松 J David Erickson 王红 Cynthia A Moore 赵平 Joseph Mulinare 洪世欣 Lee-Yang C Wong 呼和牧人 Jacqueline Gindler 郝玲 Adolfo Correa 朱慧萍 Elaine Gunter | 2000 | 中华医学杂志2000，80，7： | 185 |
| 2 | The ovarian androgen producing cells:a review ofstructure/function relationships显示文摘 | ERICKSON G F MAGOFFIN D A DYER C A etal | 1985 | Endocr Rev1985，6，3： | 1 |
| 3 | A global model of natural volatile organic compound emission 显示文摘 | Guenther A B Hewitt C N Erickson D | 1995 | Journal of Geophysical Research1995，100，： | 1 |
| 4 | Be smart, exercise your heart: exercise effects on brain and cognition 显示文摘 | Hillman C H Erickson K I Kramer A F | 2008 | Neurosci2008，9，1： | 1 |
| 5 | A global mod- el of natural volatile organic compound emissions 显示文摘 | Guenther A Hewitt C N Erickson D | 1995 | Journal of Geophysical Research1995，100，5： | 1 |
| 6 | Problem and pathological gambling are associated with poorer mental and physical health in older adults显示文摘 | ERICKSON L MOLINA C A LADD G T | 2005 | Int J Geriatric Psych2005，20，8： | 1 |
| 7 | A global model of natural volatile organic compound emissions 显示文摘 | Guenther A B Hewitt C N Erickson D | 1995 | J Geophys Res1995，100，： | 1 |
| 8 | The role of mRNA stability and transcription in O6-methylguanine-DNA methyltransferase(MGMT)expression in Mer+ human tumor cells显示文摘 | KROES R A ERICKSON L C | 1995 | Carcinogenesis1995，16，： | 1 |
| 9 | A global model of natural volatile organic compound emissions显示文摘 | GUENTHER A HEWITT C N ERICKSON D | 1995 | Jour- nal o: Geophysical Research1995，100，： | 1 |
| 10 | A global model of natural volatile organic compound emissions显示文摘 | Guenther A Hewitt C N Erickson D | 1995 | Journal of Geophysical Research1995，100，： | 1 |
| 11 | Exercise training increases size of hippocampus and improves memory显示文摘 | Erickson KI Voss MW Prakash RS Basak C Szabo A Chaddock L | | 0，，： | 1 |
| 12 | A global model of natural volatile organic compound emissions 显示文摘 | Guenther A Hewitt C N Erickson D | 1995 | J Geophys Res1995，100，5： | 1 |
| 13 | A global model of natural volatile organic compound emissions显示文摘 | Guenther A B Hewitt C N Erickson D | | 0，，5： | 1 |
| 14 | Emis- sions of sulfur trioxide from coal-fired power plants显示文摘 | Srivastava R K Miller C A Erickson C | 2004 | Journal of the Air & Waste Management Association2004，54，6： | 1 |
| 15 | Designing immunotoxins for cancer therapy 显示文摘 | Pennell C A Erickson H A | 2002 | Immunol Res2002，25，2： | 1 |
| 16 | A global-model of natural volatile organic compound emissions 显示文摘 | GUENTHER A B HEWITT C N ERICKSON D | 1995 | Journal of Geophysical Research1995，，5： | 1 |
| 17 | Neural Mechanisms of Visual Working Memory in Prefrontal Cortex of The Macaque 显示文摘 | MILLER E K ERICKSON C A DESIMONE R | 1996 | Journal of Neuroscience1996，16，16： | 1 |
| 18 | Be smart, exercise your heart: exercise effects on brain and cognition显示文摘 | HILLMAN C H ERICKSON K I KRAMER A F | 2008 | Nature Rev Neuroscience2008，1，9： | 1 |
| 19 | Disruption of the metallothionein-Ⅲgene in mice:analysis of brain zinc,behaviour,and neuron viability to metals,aging,and seizures显示文摘 | Erickson J C Hollopeter G Thomas S A | 1997 | J Neuroscience1997，17，： | 1 |
| 20 | Interior and exterior noise emitted by a fuel cell transit bus显示文摘 | Matheny M S Erickson P A Niezrecki C | 2002 | Journal of Sound and Vibration2002，251，5： | 1 |
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