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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Deter- mination of Sex Hormones and Nonylphenol Ethox- ylates in the Aqueous Matrixes of Two Pilot-scale Municipal Wastewater Treatment Plants 显示文摘 | Esperanza M Suidan M T Nishimura F | 2004 | Environ Sci Technol2004，38，： | 1 |
| 3 | In vivo 5-fluorouracil- induced apoptosis on murine thymocytes: involvement of FAS, Bax and Caspase3 显示文摘 | Aquino Esperanza J A Aguirre M V Aispuru G R | 2008 | Cell Biol Toxicol2008，24，5： | 1 |
| 4 | Kinetics of the thermal decomposition of tannery waste 显示文摘 | Caballero J A Font R Esperanza M M | 1998 | Journal of Analytical and Applied Pyrolysis1998，47，： | 1 |
| 5 | Determination of sex hormones and nonylphenol ethoxylates in the aqueous matrixes of two pilot-scale municipal wastewater treatment plants 显示文摘 | Esperanza M Suidan M T Nishimura F | 2004 | Environ Sci Teehnol2004，38，11： | 1 |
| 6 | Engineered autolytic yeast strains secreting Kluyveromyces lactis β-galactosidase for production of heterologous proteins in lactose media显示文摘 | MANUEL B ESTHER R B ESPERANZA C M | 2004 | Journal of Biotechnology2004，109，： | 1 |
| 7 | In vivo 5-fluorouracil- induced apoptosis on murine thymocytes:involvement of FAS,Bax and Caspase-3显示文摘 | AQUINO ESPERANZA J A AGUIRRE M V AISPURU G R | 2008 | Cell Biol Toxicol2008，24，5： | 1 |
| 8 | Determination of sex hormones and nonylphenol ethoxylates in the aqueous matrixes of two pilot-scale municipal wastewater treatment plants 显示文摘 | Esperanza M Suidan T Nishimura F | 2004 | Environ Sci Technol2004，38，11： | 1 |
| 9 | Galantamine postischemia provides neuroprotection and memory recovery against transient global cerebral ischemia in gerbils显示文摘 | Silvia Lorrio Mónica Sobrado Esperanza Arias | 2007 | J Pharrnacol Exp Ther2007，322，2： | 1 |
| 10 | Thermogravimetric kinetic model of the combustion of a varnish waste based on polyurethane显示文摘 | ANGELA N C FONT R ESPERANZA M M | 2001 | Energy Fuels2001，15，4： | 1 |
| 11 | Deaf Children With Cochlear Implants Do Not Appear to Use Sentence Context to Help Recognize Spoken Words显示文摘 | Conway Christopher M Deocampo Joanne A Walk Anne M Anaya Esperanza M Pisoni David B | 2014 | Journal of Speech, Language and Hearing Research2014，，6： | 1 |
| 12 | Updating channel morphology in digital elevation models: lahar assessment for Tenenepanco-Huiloac Gorge, Popocat6petI volcano, Mexico 显示文摘 | Esperanza M S Renschler C S Palacios D | 2008 | Natural Hazards2008，45，2： | 1 |
| 13 | A reduced chemical kinetic mechanism of a diesel fuel surrogate (n-heptane/toluene) for HCCI combustion modelling显示文摘 | JUAN J H JOSEP S A ESPERANZA M V | 2014 | Fuel2014，133，5： | 1 |
| 14 | Where do the odorous halogenated phenols in drinking water resources come from? 显示文摘 | BRUCHET A PROLONGEAU 12 ESPERANZA M | 2008 | Water Sci Technol: Water Supply2008，8，3： | 1 |
| 15 | Fate of sex hormones in two pilot-scale municipal wastewater treatment plants: conventional treatment显示文摘 | ESPERANZA M SUIDAN M T MARFIL-VEGA R | 2007 | Chemosphere2007，66，8： | 1 |
| 16 | Limiting the emissions of micro-pollutants: what efficiency can we expect from wastewater treatment plants? 显示文摘 | Choubert J M Rue1 S M Esperanza M | 2011 | Water Science and Technology2011，63，1： | 1 |
| 17 | Galileo Constellation Design显示文摘 | Alvaro M G Esperanza H M Ana B M P | 2001 | GPS Solutions2001，4，4： | 1 |
| 18 | Limiting the emissions of micro-pollutants:what efficiency can we expect from wastewater treatment plants显示文摘 | Choubert J M Ruel S M Esperanza M | 2011 | Water Science&Technology2011，63，1： | 1 |
| 19 | Kinetics of the thermal decomposition of tannery waste 显示文摘 | CABALLERO J A FONT R ESPERANZA M M | 1998 | Journal of Analytical and Applied Pyrolysis1998，47，2： | 1 |
| 20 | Comparison between product yields in the pyrolysis and combustion of different refuse显示文摘 | Garcia A N Esperanza M M Rafael F | 2003 | Journal of Analytical and Applied Pyrolysis2003，68，8： | 1 |
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