|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 2 | A high-density, multi-parental SNP genetic map on apple validates a new mapping approach for outcrossing species显示文摘Quantitative trait loci(QTL)mapping approaches rely on the correct ordering of molecular markers along the chromosomes,which can be obtained from genetic linkage maps or a reference genome sequence.For apple(Malus domestica Borkh),the genome sequence v1 and v2 could not meet this need;therefore,a novel approach was devised to develop a dense genetic linkage map,providing the most reliable marker-loci order for the highest possible number of markers.The approach was based on four strategies:(i)the use of multiple full-sib families,(ii)the reduction of missing information through the use of HaploBlocks and alternative calling procedures for single-nucleotide polymorphism(SNP)markers,(iii)the construction of a single backcross-type data set including all families,and(iv)a two-step map generation procedure based on the sequential inclusion of markers.The map comprises 15417 SNP markers,clustered in 3 K HaploBlock markers spanning 1267 cM,with an average distance between adjacent markers of 0.37 cM and a maximum distance of 3.29 cM.Moreover,chromosome 5 was oriented according to its homoeologous chromosome 10.This map was useful to improve the apple genome sequence,design the Axiom Apple 480 K SNP array and perform multifamily-based QTL studies.Its collinearity with the genome sequences v1 and v3 are reported.To our knowledge,this is the shortest published SNP map in apple,while including the largest number of markers,families and individuals.This result validates our methodology,proving its value for the construction of integrated linkage maps for any outbreeding species. | Erica A Di Pierro Luca Gianfranceschi Mario Di Guardo Herma JJ Koehorst-van Putten Johannes W Kruisselbrink Sara Longhi Michela Troggio Luca Bianco Hélène Muranty Giulia Pagliarani Stefano Tartarini Thomas Letschka Lidia Lozano Luis Larisa Garkava-Gustavsson Diego Micheletti Marco CAM Bink Roeland E Voorrips Ebrahimi Aziz Riccardo Velasco François Laurens W Eric van de Weg | 2016 | Horticulture Research2016，3，1： | 3 |
| 3 | Obstructive sleep apnea and heart disease: the biomarkers point of view显示文摘 | VITULANO N DI MARCO BERARDINO A RE A | 2013 | Front Biosci (Schol Ed)2013，5，： | 1 |
| 4 | Epidemiology and clinical features of Mycoplas-ma pneumoniae infection in children显示文摘 | Defilippi A Silvestri M Tacchella A Giacchino R Melioli G Di Marco E | 2008 | Resoir Med2008，102，12： | 1 |
| 5 | Physiological respons- es of European sea bass Dicentrarchus labrax to different stock- ing densities and acute stress challenge显示文摘 | Di Marco P Priori A Finoia M G | 2008 | Aquaculture2008，275，1： | 1 |
| 6 | Preparation and characterization of ealeium phosphate biomaterials 显示文摘 | CALAFIORI A R MARCO Di G MARTINO G | 2007 | J Mater Sci: Mater Med2007，18，： | 1 |
| 7 | Overview of the main methods used to combine proteins with nano systems:absorption,bioconjugation and encapsulation显示文摘 | Di Marco M Shamsuddin S Razak K A | 2010 | International Journal of Nanomedicine2010，2，5： | 1 |
| 8 | The Parkinson's disease sleep scale:a new instrument for assessing sleep and nocturnal disability in Parkinson’s disease显示文摘 | Chaudhuri K R Pal S Di Marco A | 2002 | J Neurol Neurosurg Psychiatry2002，73，6： | 1 |
| 9 | The impact of eoexistent diabetes on the prevalence of coronary heart disease 显示文摘 | MORICI M L DI MARCO A SESTITO D | 1997 | Diabetes Complication1997，11，5： | 1 |
| 10 | Model-based performance prediction in software development:a survey显示文摘 | Balsamo S di Marco A Inverardi P | | 0，，05： | 1 |
| 11 | Thermal and mechanical properties of simultaneous and sequential fullinterpenetrating polymer networks显示文摘 | Bartolotta A Di Marco G Lanza M | 2004 | Materials Science and Engineering A2004，370，： | 1 |
| 12 | Implications of Classical Scheduling Results for Real-Time Systems显示文摘 | John A Stankovic Marco Spun Marco Di Natale | 1995 | Computer1995，28，6： | 1 |
| 13 | Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine显示文摘 | Di Marco V Marzano A Lampertico P | 2004 | Hepatology2004，40，： | 1 |
| 14 | Peroxisome proliferator-activa-ted receptor-? mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives : Synthesis and biological evalua-tion 显示文摘 | Brun P Dean A Di Marco V | 2013 | Eur J Med Chem2013，62，： | 1 |
| 15 | The inhibition in vitro of DNA polymerase and RNA polymerases by daunomyein and adri- amycin 显示文摘 | Zunina F Gambetta R Di Marco A | 1975 | Biochem Pharmacol1975，24，2： | 1 |
| 16 | Periprosthetic femoral fracaares treated by locked plating: feasibility assessment of the mini-invasive surgical option: a prospective series of 36 fractures 显示文摘 | Ehlinger M Adam P Di Marco A | 2011 | Orthop Traumatol Surg Res2011，97，6： | 1 |
| 17 | Extensive disease of the thoracic aorta:hybrid treatment with the frozen elephant trunk technique显示文摘 | Di Eusan M Armaro A Di Marco L | 2011 | G Ital Cardiol(Rome)2011，12，6： | 1 |
| 18 | Learning Curves of the Airtraq and the Macintosh laryngoscopes for tracheal intubation by novice laryngoscnpists:a clinical study显示文摘 | Di Marco P Scattoni L Spinoglio A | | 0，，01： | 1 |
| 19 | Short-and midtel'm'reSults after hybridtreatmerttlof chronic artic dissection with the frozen eiephant trunk technique显示文摘 | Di Eusanio M aro A Di Marco L | 2011 | E''[I Eardi thorac Surg2011，40，4： | 1 |
| 20 | Visceral organ protec- tion in aortic arch surgery: safety of moderate hypothermia 显示文摘 | Pacini D Pantaleo A Di Marco L | 2014 | Eur J Cardiothorac Surg2014，46，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员