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| 1 | Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia. | Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng | 2015 | World Journal of Gastroenterology2015，21，42： | 2 |
| 2 | Neuropeptides, food intake and body weight regulation: A hypothalamic focus显示文摘 | HILLEBRAND J J G DEWIED D ADAN R A H | 2002 | Peptides2002，23，： | 1 |
| 3 | Minimal processing and edible coating effects on composition and sensory quality of mini-peeled carrots显示文摘 | Howard L R Dewi T | 1996 | Journal of Food Science1996，61，3： | 1 |
| 4 | Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific显示文摘 | Dewi D A Abayasekara D R E Wheeler-Jones C P D | 2001 | J Clin Endocrinol Metab2001，86，： | 1 |
| 5 | The effects of shopping orientations,consumer innovativeness,purchase experience,and gender on intention to shop for fashion products online显示文摘 | Nirmala R P Dewi I J | 2011 | Gadjah Mada International Journal of Business2011，13，1： | 1 |
| 6 | The effects of shopping orientations,consumer innovativeness,purchase experience,and gender on intention to shop for fashion products online显示文摘 | NIRMALA R P DEWI I J | 2011 | Gadjah mada international journal of business2011，13，1： | 1 |
| 7 | A-gis Based Approach of Evacuation Model for Tsunami Risk Reduction 显示文摘 | Dewi R S | 2012 | IDRiM Journal ($2185-8322)2012，2，2： | 1 |
| 8 | Methylation impact analysis of erythropoietin (EPO) Gene to hypoxia inducible factor - let(HIF - lc) activity显示文摘 | DEWI F R FATCHIYAH F | 2013 | Bioinformation2013，9，15： | 1 |
| 9 | PEPCK coordinates the regulation of centralcarbon metabolism to promote cancer cell growth显示文摘 | Montal E D Dewi R Bhalla K | 2015 | Mol Cell2015，60，4： | 1 |
| 10 | The diagnostic value of the ELISA-Ty test for the detection of typhoid fever in children显示文摘 | Handojo I Dewi R | 2000 | Southeast Asian J Trap Med Public Health2000，31，4： | 1 |
| 11 | Methylation impact analysis of erythropoietin (EPO) Gene to hypoxia inducible factor-1α (HIF-1α) activity显示文摘 | Dewi F R Fatchiyah F | 2013 | Bioinformation2013，9，15： | 1 |
| 12 | Peroxidation enhances the bio- gas production in the anaerobic digestion ofbiosolids显示文摘 | DEWI R APPELS L BAEYENS J | 2007 | J Hazard Mater2007，146，3： | 1 |
| 13 | Minimal Processing and Edible Coating Effects on Composition and Sensory Quality of Mini-peeled Carrots 显示文摘 | Howard L R Dewi T | 1996 | Food Science1996，61，： | 1 |
| 14 | Comparison of the strength of barncle and commercial dental cements显示文摘 | Despain R R Dewies K L Luntz R D | 1973 | J Dent Res1973，52，4： | 1 |
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