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| 1 | Ammonia Sensing System Based on Wavelength Modulation Spectroscopy显示文摘在近红外线的区域的一个察觉到的系统为基于波长调整光谱学 WMS 原则察觉到的氨被开发了。WMS 是为检测原子 / 分子的种类的一种相当敏感的技术,介绍它能在由使用光电信技术的在红外线附近的区域被使用的优点。在这种技术,激光波长和紧张被通过注射水流使用一个正弦波浪信号调制,它允许察觉带宽的移动到激光紧张噪音典型地更低的更高的频率。二个多传递房间基于有 160 厘米和 16 厘米光路径长度的空间光繁殖被使用,允许冗余性操作和技术确认。这个系统在 1512.21 nm 与排放波长使用了二极管激光,在的地方 NH < 潜水艇 class= “ a-plus-plus ” > 3 有一根强壮的吸收线。NH 的控制 < 潜水艇 class= “ a-plus-plus ” > 3 气体察觉到系统,以及获得,处理并且数据表示被执行。 | Duarte VIVEIROS Joao FERREIRA Susana O. SILVA Joana RIBEIRO Deolinda FLORES Jose L. SANTOS Orlando FRAZAO Jose M. BAPTISTA | 2015 | Photonic Sensors2015，5，2： | 3 |
| 2 | Ovarian cancer and DNA repair: DNA ligase IV as a potential key显示文摘Ovarian cancer(OC)is the sixth most common cancer and the seventh cause of death from cancer in women.The etiology and the ovarian carcinogenesis still need clarification although ovulation may be determinant due to its carcinogenic role in ovarian surface epithelium.The link between ovarian carcinogenesis and DNA repair is well established and it became clear that alterations in DNA damage response may affect the risk to develop OC.Polymorphisms are variations in the DNA sequence that exist in normal individuals of a population and are capable to change,among other mechanisms,the balance between DNA damage and cellular response.Consequently,genetic variability of the host has a great role in the development,progression and consequent prognosis of the oncologic patient as well as in treatment response.Standard treatment for OC patients is based on cytoreductive surgery,followed by chemotherapy with a platinum agent and a taxane.Although 80%of the patients respond to the first-line therapy,the development of resistance is common although the mechanisms underlying therapy failure remain mostly unknown.Because of their role in oncology,enzymes involved in the DNA repair pathways,like DNA Ligase IV(LIG4),became attractive study targets.It has been reported that variations in LIG4 activity can lead to a hyper-sensitivity to DNA damage,deregulation of repair and apoptosis mechanisms,affecting the susceptibility to cancer development and therapy response.To overcome resistance mechanisms,several investigations have been made and the strategy to target crucial molecular pathways,such as DNA repair,became one of the important areas in clinical oncology.This review aims to elucidate the link between DNA repair and OC,namely which concerns the role of LIG4 enzyme,and how genetic polymorphisms in LIG4 gene can modulate the activity of the enzyme and affect the ovarian carcinogenesis and treatment response.Moreover,we try to understand how LIG4 inhibition can be a potential contributor for the development of new cancer treatment strategies. | Joana Assis Deolinda Pereira Rui Medeiros | 2013 | World Journal of Clinical Oncology2013，4，1： | 2 |
| 3 | Insight into p95HER2 in Breast Cancer: Molecular Mechanisms and Targeted Therapies显示文摘 | Ramon Andrade de Mello Alessandro de Vasconcelos Ronaldo A Ribeiro Ines Pousa Noemia Afonso Deolinda Pereira Helena Rodrigues | 2012 | Recent Patents on DNA and Gene Sequences2012，，1： | 1 |
| 4 | Molecular epidemiology and antimicrobial susceptibility of extended- and broad-spectrum β-lactamase-producing Klebsiella pneumoniae isolated in Portugal显示文摘 | Nuno Mendon?a Eugénia Ferreira Deolinda Louro Manuela Cani?a | 2009 | International Journal of Antimicrobial Agents2009，，1： | 1 |
| 5 | DNA repair polymorphisms might contribute differentially on familial and sporadic breast cancer susceptibility: a study on a Portuguese population显示文摘 | Sandra Costa Daniela Pinto Deolinda Pereira Helena Rodrigues Jorge Cameselle-Teijeiro Rui Medeiros Fernando Schmitt | 2007 | Breast Cancer Research and Treatment2007，，2： | 1 |
| 6 | Ultrastructural and growth factor analysis of amniotic membrane preserved by different methods for ocular surgery显示文摘 | Deolinda de Oliveira Pena J Melo GB Gomes JA | 2007 | Arq Bras Oftalmol2007，70，5： | 1 |
| 7 | Review and update of the applications of organic petrology: Part 1, geological applications显示文摘 | Isabel Suárez-Ruiz Deolinda Flores Jo?o Graciano Mendon?a Filho Paul C. Hackley | 2012 | International Journal of Coal Geology2012，，： | 1 |
| 8 | Case study of igneous intrusion effects on coal nitrogen functionalities显示文摘 | Bruno Valentim Alexandra Guedes Sandra Rodrigues Deolinda Flores | 2011 | International Journal of Coal Geology2011，，2： | 1 |
| 9 | Insight into p95HER2 in Breast Cancer: Molecular Mechanisms and Targeted Therapies显示文摘 | Ramon Andrade de Mello Alessandro de Vasconcelos Ronaldo A Ribeiro Ines Pousa Noemia Afonso Deolinda Pereira Helena Rodrigues | 2012 | Recent Patents on DNA and Gene Sequences2012，，1： | 1 |
| 10 | Role of the RAD51 G172T polymorphism in the clinical outcome of cervical cancer patients under concomitant chemoradiotherapy显示文摘 | Augusto Nogueira Raquel Catarino Ilda Faustino Cristina Nogueira-Silva Tiago Figueiredo Liliana Lombo Inês Hilário-Silva Deolinda Pereira Rui Medeiros | 2012 | Gene2012，，2： | 1 |
| 11 | G-308A TNF-α polymorphism is associated with an increased risk of invasive cervical cancer显示文摘 | Isabel Duarte Alexandra Santos Hugo Sousa Raquel Catarino Daniela Pinto Ana Matos Deolinda Pereira José Moutinho Paulo Canedo José Carlos Machado Rui Medeiros | 2005 | Biochemical and Biophysical Research Communications2005，，2： | 1 |
| 12 | Identification of nanominerals and nanoparticles in burning coal waste piles from Portugal显示文摘 | Joana Ribeiro Deolinda Flores Colin R. Ward Luis F.O. Silva | 2010 | Science of the Total Environment2010，，23： | 1 |
| 13 | 煤中有毒有机物质的健康效应:“流行性”肾病显示文摘煤含有无数有机化合物,一些是已知的有毒化合物,其它具有潜在的毒性。煤中发现的特别值得关注的有毒有机化合物包括:1)稠环芳烃结构(例如多环芳烃),它可作为诱变剂、促癌剂、内分泌干扰物;2)芳胺,它具有潜在的肾毒性;3)杂环化合物。它为致癌物和肾毒性物质。有毒有机化合物可由煤中渗透入水源,人体长期暴露于这些化合物可导致疾病的产生, | William Orem Calin Tatu Nikola Pavlovic Joseph Bunnell Harry Lerch Virgil Paunescu Valentin Ordodi Deolinda Flores Margo Corum Anne Bates 周群芳(译) | 2007 | AMBIO-人类环境杂志2007，36，1： | 0 |
| 14 | Vitamin D in Food Supplements:Labeling Survey显示文摘An adequate vitamin D(vitD)intake(Recommended Daily Allowance,RDA=5μg)is crucial for health maintenance and its deficiency is associated with several health problems.The increase in hypovitaminosis D cases and the proliferation of food supplements(FS)that are easily accessible by the population,have led to an unrestrained chronic consumption of FS.VitD may accumulate in the body and originate toxicity(Tolerable Upper Limit,UL=100μg).The aim of this study was to evaluate if daily vitD doses mentioned in FS labels are in conformity with RDA.210 solid and liquid FS(for pediatrics and adults)sold in Portuguese pharmacies,supermarkets,health shops and on the internet were examined for indicated daily intake of vitD and compared to RDA and UL values.51.43%of FS have values higher than RDA,8.57%higher than UL.The average vitD daily dose in FS is 24.48μg,with a high variability between samples(0.25-250μg).Majority of FS labels recommend vitD daily doses above RDA and some even above UL,regardless of being for adults or children.Therefore,it is crucial that vitD dose in FS is reviewed to ensure the safety of these products. | Alexandra Figueiredo Maria Deolinda Auxtero Maria Guilhermina Moutinho Inês Neves Raquel Inez Isabel Margarida Costa | 2021 | Journal of Integrative Medicine(双语)2021，10，2： | 0 |
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