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| 1 | Robotic surgery for rectal cancer: A systematic review of current practice显示文摘AIM: To give a comprehensive review of current litera-ture on robotic rectal cancer surgery.METHODS: A systematic review of current literature via PubMed and Embase search engines was per-formed to identify relevant articles from january 2007 to november 2013. The keywords used were: 'robotic surgery', 'surgical robotics', 'laparoscopic computer-assisted surgery', 'colectomy' and 'rectal resection'. RESULTS: After the initial screen of 380 articles, 20 pa-pers were selected for review. A total of 1062 patients(male 64.0%) with a mean age of 61.1 years and body mass index of 24.9 kg/m2 were included in the review.Out of 1062 robotic-assisted operations, 831(78.2%) anterior and low anterior resections, 132(12.4%) in-tersphincteric resection with coloanal anastomosis, 98(9.3%) abdominoperineal resections and 1(0.1%) Hart-mann's operation were included in the review. Robotic rectal surgery was associated with longer operative time but with comparable oncological results and anastomotic leak rate when compared with laparoscopic rectal surgery. CONCLUSION: Robotic colorectal surgery has con-tinued to evolve to its current state with promising re-sults; feasible surgical option with low conversion rate and comparable short-term oncological results. The challenges faced with robotic surgery are for more high quality studies to justify its cost. | Tony Wing Chung Mak Janet Fung Yee Lee Kaori Futaba Sophie Sok Fei Hon Dennis Kwok Yu Ngo Simon Siu Man Ng | 2014 | World Journal of Gastrointestinal Oncology2014，6，6： | 16 |
| 2 | Quality of life after laparoscopic vs open sphincter-preserving resection for rectal cancer显示文摘AIM: To compare quality of life (QoL) outcomes in Chinese patients after curative laparoscopic vs open surgery for rectal cancer. METHODS: Eligible Chinese patients with rectal cancer undergoing curative laparoscopic or open sphincterpreserving resection between July 2006 and July 2008 were enrolled in this prospective study. The QoL outcomes were assessed longitudinally using the validated Chinese versions of the European Organization for Research and Treatment of Cancer QLQ-C30 and QLQCR38 questionnaires before surgery and at 4, 8, and 12 mo after surgery. The QoL scores at the different time points were compared between the laparoscopic and open groups. A higher score on a functional scale indicated better functioning, whereas a higher score on a symptom scale indicated a higher degree of symptoms.RESULTS: Seventy-four patients (49 laparoscopic and 25 open) were enrolled. The two groups of patients were comparable in terms of sociodemographic data, types of surgery, tumor staging, and baseline mean QoL scores. There was no significant decrease from baseline in global QoL for the laparoscopic group at different time points, whereas the global QoL was worse compared to baseline beginning at 4 mo but returned to baseline by 12 mo for the open group (P = 0.019, Friedman test). Compared to the open group, the laparoscopic group had significantly better physical (89.9±1.4 vs 79.2±3.7, P = 0.016), role (85.0±3.4 vs 63.3±6.9, P = 0.005), and cognitive (73.5±3.4 vs 50.7±6.2, P = 0.002) functioning at 8 mo, fewer micturition problems at 4-8 mo (4 mo: 32.3±4.7 vs 54.7±7.1, P = 0.011; 8 mo: 22.8±4.0 vs 40.7±6.9, P = 0.020), and fewer male sexual problems from 8 mo onward (20.0±8.5 vs 76.7±14.5, P = 0.013). At 12 mo after surgery, no significant differences were observed in any functional or symptom scale between the two groups, with the exception of male sexual problems, which remained worse in the open group (29.2±11.3 vs 80.0±9.7, P = 0.026). CONCLUSION: Laparoscopic sphincter-preserving resection for rectal cancer is associated with better preservation of QoL and fewer male sexual problems when compared with open surgery in Chinese patients. These findings, however, should be interpreted with caution because of the small sample size of the study. | Simon Siu-Man Ng Wing-Wa Leung Cherry Yee-Ni Wong Sophie Sok-Fei Hon Tony Wing-Chung Mak Dennis KwokYu Ngo Janet Fung-Yee Lee | 2013 | World Journal of Gastroenterology2013，19，29： | 6 |
| 3 | Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model显示文摘在最近的十年,从动物和临床的研究积累证据建议了一个足够地激活的免疫系统可以强烈扩充癌症治疗的各种各样的类型,包括光力学的治疗(太平洋夏季时间) 。通过反应的氧种类的产生,太平洋夏季时间根除由触发局部性的肿瘤损坏并且导致反肿瘤免疫的肿瘤。作为反肿瘤免疫的主要部件,在太平洋夏季时间的调停房间的有免疫力的回答的参与很好在过去的十年被调查了,而体液的免疫的角色仍然保持相对未经勘探。在现在的调查,使用 photosensitizer BAM-SiPc 和 CT26 忍受肿瘤的 BALB/c 老鼠模型,调停房间、体液的适应有免疫力的部件能涉及太平洋夏季时间,这被表明。与脉管的太平洋夏季时间(VPDT ) 政体, BAM-SiPc 能根除 ~ 的肿瘤 70 %忍受肿瘤的老鼠和扳机能持续超过 1 年的反肿瘤免疫者回答。Th2 cytokines 的举起是在 VPDT 以后的检测前 vivo,显示体液的回答的潜在的参与。从治好 VPDT 的老鼠的浆液的分析也揭示了肿瘤特定的抗体的提高的层次。而且,这浆液能有效地妨碍肿瘤生长并且保护老鼠免于进一步以一种 T-cell-dependent 方式重新质问。一起拿,体液的部件在 BAM-SiPc-VPDT 以后导致了的这些结果表演能帮助反肿瘤免疫的发展。 | Hing-Yuen Yeung Pui-Chi Lo Dennis K.P. Ng Wing-Ping Fong | 2017 | Cellular & Molecular Immunology2017，14，2： | 4 |
| 4 | Obstructive jaundice due to a rare periampullary tumor显示文摘Gangliocytic paraganglioma is a rare neuroendocrine tumor predominantly arising in the second part of the duodenum with rare local recurrence or metastasis to regional lymph nodes.A 92-year-old female presented with obstructive jaundice.On exam she had pale conjunctiva and icteric sclera.Abdominal examination revealed tenderness in the upper abdomen.Laboratory data was consistent with obstructive jaundice.Computed tomography of the abdomen revealed a dilated gall bladder and a common bile duct(CBD)with no evidence of liver lesions or pancreatic head mass.Endoscopic ultrasonography revealed a 1 cm isoechoic submucosal nodule at the periampullary area,dilated CBD(9 mm),a prominent pancreatic duct(4.1 mm)and a hydropic gall bladder with no stones.Endoscopic retrograde cholangiopancreaticography was performed to relieve obstruction and showed a 1 cm periampullary mass which underwent an en-bloc snare resection.Histopathology analyses with immunohistochemical stains were positive for cytokeratin,synaptophysin,S-100 protein,neuron specific enolase and negative for actin and desmin consistent with periampullary gangliocytic paraganglioma.Periampullary gangliocytic paraganglioma is a rare benign tumor of the small bowel.Common presentation includes abdominal pain and obstructive jaundice which should be included in differential diagnosis of obstructive jaundice.Endoscopic resection is a curative therapy in the absence of local invasion or distant metastasis. | Anjana Sathyamurthy Abhishek Choudhary Dennis Ng Shuaib Okponobi Alberto Diaz-Arias Ajitinder Grewal Ghassan M Hammoud | 2013 | World Journal of Gastrointestinal Oncology2013，5，10： | 2 |
| 5 | Efficacy and tolerability of vardenafil in Asian men with erectile dysfunction显示文摘瞄准:评估功效和 vardenafil 的 toler 能力,一个 phosphodiesterase type-5 (PDE-5 ) 禁止者,在有可勃起的机能障碍(编辑) 的亚洲种族的人。方法:在这未来,双窗帘,多民族的学习,亚洲人被使随机化收到 vardenafil (10 mg ) 或安慰剂(4:1 比率) 12 个星期。主要功效变量是可勃起的功能的国际索引可勃起的功能领域(IIEF-EF ) ,和性相遇侧面(9 月) 与穿入和交际结束有关询问。重要吝啬的改进在所有三项措施被要求显示出 vardenafil 处理的积极好处。第二等的功效变量在勃起改进上包括了全球评价问题(GAQ ) 。结果:最少平方的吝啬的基线 IIEF-EF 领域分数(vardenafil 14.6,安慰剂 13.4 ) 与在 12 个星期以后的中等编辑一致, vardenafil 处理与安慰剂相比在 IIEF-EF 领域分数从基线与重要增加被联系(22.4 对 14.3;P <
0.001 ) 。Vardenafil 在吝啬的成功为 SEP-2 评估的最少的广场(LS ) 从基线与重要改进被联系(vardenafil 82.2 对安慰剂 43.6;P <
0.001 ) 并且 SEP-3 (vardenafil 66.1 对安慰剂 24.0;P <
0.001 ) 。积极 GAQ 回答被 81.8% vardenafil 接受者对 24.3% 安慰剂接受者报导。不利事件被 25.4% vardenafil 组,报导温和、短暂的多数。结论:Vardenafil (10 mg ) 是为在亚洲男人的中等编辑的一个高度有效、容忍得好的处理。这些结果增加在耐心的人口的一个范围为编辑的治疗表明 vardenafil 的安全和功效的数据的增加的数量。 | Hui Meng Tan Chong Min Chin Chong Beng Chua Edsal Gatchalian Apichat Kongkanand Clarence Lei Chang Moh Foo Cheong Ng Krisada Ratana-Olarn Dennis Serrano Akmal Taher Ismail Tambi Anupan Tantiwong Michael Wong Yuet Chen Wai-Chun Yip | 2008 | Asian Journal of Andrology2008，10，3： | 2 |
| 6 | Endo-Laparoscopic Colectomy Without Mini-Laparotomy for Left-Sided Colonic Tumors显示文摘 | Hester Y. S. Cheung Alex L. H. Leung C. C. Chung Dennis C. K. Ng Michael K. W. Li | 2009 | World Journal of Surgery2009，，6： | 1 |
| 7 | Synthesis and characterization of meso-ferrocenylethynyl 5,15-diphenylporphyrins显示文摘 | Ka-Lok Cheng Hung-Wing Li Dennis K P Ng | 2004 | Organometallic Chemistry2004，689，9： | 1 |
| 8 | Laparoscopic-assisted versus open total mesorectal excision with anal sphincter preservation for mid and low rectal cancer: a prospective, randomized trial显示文摘 | Simon S. M. Ng Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Sophie S. F. Hon Tony W. C. Mak Dennis K. Y. Ngo Wing Wa Leung Ka Lau Leung | 2014 | Surgical Endoscopy2014，，1： | 1 |
| 9 | Endo-Laparoscopic Colectomy Without Mini-Laparotomy for Left-Sided Colonic Tumors显示文摘 | Hester Y. S. Cheung Alex L. H. Leung C. C. Chung Dennis C. K. Ng Michael K. W. Li | 2009 | World Journal of Surgery2009，，6： | 1 |
| 10 | Spectroscopic study of electron and energy transfer in novel silicon phthalocyanine-boron dipyrromethene triads 显示文摘 | Ermilov Eugeny A Liu Jianyong Ng Dennis K P | 2009 | Phys Chem Chem Phys2009，11，30： | 1 |
| 11 | Hand-assisted Laparoscopic Versus Open Right Colectomy: A Randomized Controlled Trial显示文摘 | Chi Chiu Chung Dennis Chung Kei Ng Wilson Wen Chieng Tsang Wai Lun Tang Kevin Kwok Kay Yau Hester Yui Shan Cheung James Cheuk Hoo Wong Michael Ka Wah Li | 2007 | Annals of Surgery2007，，5： | 1 |
| 12 | Disturbance decoupled fault reconstruction using cascaded sliding mode observers 显示文摘 | Kok Yew Ng Chee Pin Tan Denny Oetomo | 2012 | Automatica2012，48，5： | 1 |
| 13 | Synthesis of distributed wastewater treatment networks for one- and two-contaminant systems显示文摘 | Sarah S.T. Soo Ee Ling Toh Kevin K.K. Yap Denny K.S. Ng Dominic C.Y. Foo | 2013 | Chemical Engineering Research and Design2013，，1： | 1 |
| 14 | Graphical approach to minimum flowrate targeting for partitioning water pretreatment units显示文摘 | Raymond R. Tan Denny K.S. Ng Dominic C.Y. Foo | 2009 | Chemical Engineering Research and Design2009，，4： | 1 |
| 15 | Phthalocyanine synthesis in ionic liquids: preparation of differently substituted phthalocyanines in tetrabutylammonium bromide 显示文摘 | Pui-Chi Lo Diana Y Y Cheng Dennis K P Ng | 2005 | Synthesis2005，，7： | 1 |
| 16 | Assessing the effects of age on long white matter tracts using diffusion tensor tractography显示文摘 | Davis SW Dennis NA Buchler NG | 2009 | Neuroimage2009，46，2： | 1 |
| 17 | Laparoscopic Resection for Rectal Cancers: Lessons Learned From 579 Cases显示文摘 | Kheng-Hong Ng Dennis Chung-Kei Ng Hester Yui-Shan Cheung James Cheuk-Hoo Wong Kevin Kwok-Kay Yau Clift Chi-Chiu Chung Michael Ka-Wah Li | 2009 | Annals of Surgery2009，，： | 1 |
| 18 | An Ensemble Multiscale Filter for Large Nonlinear Data Assimilation Problems显示文摘 | Zhou Yuhua McLaughlin Dennis Entekhabi Dara Ng Gene-Hua Crystal | 2008 | Monthly Weather Review2008，，2： | 1 |
| 19 | Efficient and recyclable phthalocyanine based sensitizers for photooxygenation reactions显示文摘 | Xu Hu Chan Wing-Kin Ng Dennis K P | 2009 | Synthesis2009，，11： | 1 |
| 20 | Effects of Coupling Agent on the Physical Properties of Wood-polymer Composites显示文摘 | Shane B Elvy Gary R Dennis Loo-Teck Ng | 1995 | Journal of Materials Processing Technology1995，48，： | 1 |
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