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您的检索式：作者名="Deike Varoga"
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| 1 | Enhanced microfracture techniques in cartilage knee surgery: Fact or fiction?显示文摘The limited intrinsic healing potential of human articular cartilage is a well-known problem in orthopedic surgery. Thus a variety of surgical techniques have been developed to reduce joint pain, improve joint function and delay the onset of osteoarthritis. Microfractures as a bone marrow stimulation technique present the most common applied articular cartilage repair procedure today. Unfortunately the deficiencies of fibrocartilaginous repair tissue inevitably lead to breakdown under normal joint loading and clinical results deteriorate with time. To overcome the shortcomings of microfracture, an enhanced microfracture technique was developed with an additional collagen Ⅰ/Ⅲ membrane(Autologous, Matrix-Induced Chondrogenesis, AMIC). This article reviews the pre-clinical rationale of microfractures and AMIC, presents clinical studies and shows the advantages and disadvantages of these widely usedtechniques. PubM ed and the Cochrane database were searched to identify relevant studies. We used a comprehensive search strategy with no date or language restrictions to locate studies that examined the AMIC technique and microfracture. Search keywords included cartilage, microfracture, AMIC, knee, ChondroGide. Besides this, we included our own experiences and study authors were contacted if more and non published data were needed. Both cartilage repair techniques represent an effective and safe method of treating full-thickness chondral defects of the knee in selected cases. While results after microfracture deteriorate with time, mid-term results after AMIC seem to be enduring. Randomized studies with long-term followup are needed whether the grafted area will maintain functional improvement and structural integrity over time. | Stefan Bark Tomasz Piontek Peter Behrens Sabiah Mkalaluh Deike Varoga Justus Gille | 2014 | World Journal of Orthopedics2014，5，4： | 3 |
| 2 | The systemic angiogenic response during bone healing显示文摘 | Stefan Weiss Gerald Zimmermann Thomas Pufe Deike Varoga Philipp Henle | 2009 | Archives of Orthopaedic and Trauma Surgery2009，，： | 1 |
| 3 | The Treatment of Intra-articular Calcaneus Fractures with Severe Soft Tissue Damage with a Hinged External Fixator or Internal Stabilization: Long-term Results显示文摘 | Lutz Besch Jan Soeren Waldschmidt Mark Daniels-Wredenhagen Deike Varoga Michael Mueller Ralf-Erik Hilgert Guenther Mathiak Stefanie Oestern Sebastian Lippross Andreas Seekamp | 2010 | The Journal of Foot and Ankle Surgery2010，，1： | 1 |
| 4 | Multiple trauma induces serum production of host defence peptides显示文摘 | Sebastian Lippross Tim Klueter Nadine Steubesand Stefanie Oestern Rolf Mentlein Frank Hildebrandt Rainer Podschun Thomas Pufe Andreas Seekamp Deike Varoga | 2011 | Injury2011，，2： | 1 |
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