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| 1 | Development of hepatorenal syndrome in bile duct ligated rats显示文摘AIM: To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS: Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function parameters, rats wereplaced in metabolic cages and, at the end of the experiment, blood and urine samples were obtained. Histology and hydroxyproline content were analyzed in liver and renal tissue. RESULTS: Rats with 2 wk of BDL increased free water clearance (P = 0.02), reduced urinary osmolality (P = 0.03) and serum creatinine (P = 0.01) in comparison to the sham group. In contrast, rats at 6 wk of BDL showed features of HRS, including signif icant increase in serum creatinine and reductions in creatinine clearance, water excretion and urinary sodium concentration. Rats with 4 wk of BDL exhibited an intermediate stage of renal dysfunction. Progressive hepatic f ibrosis according to post-procedure time was confirmed by histology. The increased levels of liver hydroxyproline contrasted with the absence of structural changes in the kidney, as assessed by histology and unchanged hydroxyproline content in renal tissue. CONCLUSION: Our data show that BDL produced progressive renal dysfunction without structural changes in the kidney, characterizing HRS. The present model will be useful to understand the pathophysiology of HRS. | Regina M Pereira Robson AS dos Santos Eduardo A Oliveira Virgínia HR Leite Filipi LC Dias Alysson S Rezende Lincoln P Costa Lucíola S Barcelos Mauro M Teixeira Ana Cristina Sim■es e Silva | 2008 | World Journal of Gastroenterology2008，14，28： | 2 |
| 2 | Dehydration of xylose into furfural over micro-mesoporous sulfonic acid catalysts显示文摘 | Ana S Dias Martyn Pillinger Anabela A Valente | 2005 | Journal of Catalysis2005，229，2： | 1 |
| 3 | Modification of wheat straw lignin by solid state fermentation with white-rot fungi显示文摘 | Maria J. Dinis Rui M.F. Bezerra Fernando Nunes Albino A. Dias Cristina V. Guedes Luís M.M. Ferreira John W. Cone Guilhermina S.M. Marques Ana R.N. Barros Miguel A.M. Rodrigues | 2009 | Bioresource Technology2009，，20： | 1 |
| 4 | Exfoliated titanate, niobate and titanoniobate nanosheets as solid acid catalysts for the liquid-phase dehydration of d -xylose into furfural显示文摘 | Ana S. Dias Sérgio Lima Daniel Carriazo Vicente Rives Martyn Pillinger Anabela A. Valente | 2006 | Journal of Catalysis2006，，2： | 1 |
| 5 | Actinic prurigo of the lip: Two case reports显示文摘Actinic prurigo is a photodermatosis that can affect the skin, conjunctiva and lips. It is caused by an abnormal reaction to sunlight and is more common in high-altitude living people, mainly in indigenous descendants. The diagnosis of actinic prurigo can be challenging, mainly when lip lesions are the only manifestation, which is not a common clinical presentation. The aim of this article is to report two cases of actinic prurigo showing only lip lesions. The patients were Afro-American and were unaware of possible Indian ancestry. Clinical exam, photographs, videoroscopy examination and biopsy were performed, and the diagnosis of actinic prurigo was established. Topical corticosteroid and lip balm with ultraviolet protection were prescribed with excellent results. The relevance of this report is to show that although some patients may not demonstrate the classical clinical presentation of actinic prurigo, the associated clinical and histological exams are determinants for the correct diagnosis and successful treatment of this disease. | Ana MO Miranda Thiago M Ferrari Juliana T Werneck Arley Silva Junior Karin S Cunha Eliane P Dias | 2014 | World Journal of Clinical Cases2014，2，8： | 1 |
| 6 | Dehydration of xylose into furfural over micro-mesoporous sulfonic acid catalysts显示文摘 | Dias Ana S Pillinger Martyn Valente Anabela A | 2005 | Journal of Catalysis2005，229，： | 1 |
| 7 | Modified versions of sulfated zirconia as catalysts for the conversion of xylose to furfural 显示文摘 | Dias Ana S Lima Sergio Pillinger Martyn | 2007 | Catalysis Letters2007，114，34： | 1 |
| 8 | Dehydration of xylose into furfural over micro-mesoporous sulfonic acid catalysts 显示文摘 | Dias Ana S Pillinger Martyn Valente Anabela A | 2005 | Journal of Catalysis2005，229，2： | 1 |
| 9 | Mesoporous silica-supported 12-tungstophosphoric acid catalysts for the liquid phase dehydration of D-xylose 显示文摘 | Dias Ana S Pillinger Martyn Valente Anabela A | 2006 | Microporous and Mesoporous Materials2006，94，13： | 1 |
| 10 | Liquid-phase dehydration of D-xylose over microporous and mesoporous niobium silicates 显示文摘 | Dias Ana S Lima Sergio Brandao Paula | 2006 | Catalysis Letters2006，108，34： | 1 |
| 11 | Liquid phase dehydration of d-xylose in the presence of Keggintype heteropolyacids显示文摘 | Ana S Dias Martyn Pillinger Anabela A Valente | 2005 | Appl Cata A2005，285，： | 1 |
| 12 | Dehydration of xvlose into furfural over micro-mesoporous suIfonic acid eatalysts显示文摘 | DIAS Ana S Pillinger Martyn Valente Anabela A | 2005 | Journalof Catal ysls2005，229，： | 1 |
| 13 | Liquid phase dehydration of D-xylose in the presence of Keggin-type heteropolyacids显示文摘 | Ana S Dias Martyn Pillinger Anabela A Valente | 2005 | Applied Catalysis A2005，285，12： | 1 |
| 14 | Nutritional,rheological and sensory properties of butter processed with different mixtures of cow and sheep milk cream显示文摘This study assessed the quality parameters and consumer perception and behavior of butter processed with different ratios of cow and sheep milk cream.Cow milk cream butter(CMCB)showed lower moisture content and higher fat content,smaller fat globules,and higher concentrations of long-chain saturated fatty acids and monounsaturated fatty acids,resulting in improved potential health indices.In addition,CMCB showed yellow color,little salt,and butter taste as the main sensory characteristics,resulting in grateful and good digestibility perceptions.Sheep milk cream addition improved the rheological properties of the products(lower viscosity,consistency index,and rigidity(J0),and higher fluidity and viscoelastic behavior(J1)),mainly due to the increased concentrations of short-chain and medium-chain saturated fatty acids and polyunsaturated fatty acids.However,sheep milk cream butter(SMCB)was characterized by a greasy and striking aroma,with a lower perception of good digestibility and good appearance,and a higher bitter taste.The association of cow and sheep milk cream could be an exciting option to obtain products with improved fatty acid profiles,health indices,and yet maintain desired rheological and sensory properties.The formulation with 60%sheep milk cream and 40%cow milk cream would be the suggested combination. | Renata S Dias Celso F.Balthazar Rodrigo N.Cavalcanti Louise A.Sobral Jessica F.Rodrigues Roberto P.CNeto Maria Inˆes B.Tavares Ana Paula B.Ribeiro Renato Grimaldi Celso Sant’Anna Erick A.Esmerino Tatiana C.Pimentel Marcia Cristina Silva Adriano G.Cruz | 2022 | Food Bioscience2022，46，2： | 1 |
| 15 | Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey显示文摘 | Letícia Estevinho Ana Paula Pereira Leandro Moreira Luís G. Dias Ermelinda Pereira | 2008 | Food and Chemical Toxicology2008，，12： | 1 |
| 16 | Degradation of a textile reactive Azo dye by a combined chemical-biological process: Fenton's reagent-yeast显示文摘 | Marco S Lucas Albino A Dias Ana Sampaio | 2007 | Water Research2007，41，： | 1 |
| 17 | Liquid phase dehydration of D-xylose in the presence of Keggin-type heteropolyacids显示文摘 | DIAS ANA S PILLINGER MARTYN ANABELA A | 2005 | Applied Catalysis A: General2005，285，12： | 1 |
| 18 | ^(222)Rn calibration procedure for water analyses by liquid scintillation counting显示文摘Purpose Among the several methods to measure ^(222)Rn in water,the liquid scintillation counting(LSC)technique is one of the most sensitive and widely used when analysing non-saline waters by liquid extraction,providing excellent accuracy,precision and low-level detection limits.When using the liquid scintillation counter Tri-Carb 3170 TR/SL(Perkin-Elmer)it is not possible to make an automatic determination of the alpha/beta discrimination parameter,being necessary to evaluate the pulse decay discriminator(PDD)value manually to the ^(222)Rn determination.In this work,we describe the steps to perform the calibration of that type of equipment.Methods The method consists in the preparation of standard samples from a ^(226)Ra certified standard solution and the adjustment of the PDD value by hand until the percentage of alpha events reaches a plateau of a near-constant fraction of total events.The process consists in taking several measures between PDD 80 and 200 with 15 min counting time each.Within the plateau,the alpha/beta ratio was used to determine the plateau final range as well as the optimum PDD value.After that,the calibration standards and blanks were measured and the region of interest(ROI)was established by finding the maximum value for the figure of merit(FOM)in the upper and lower limits.Results The optimal PDD value of 148 was established by the alpha/beta ratio,and after that,it was possible to measure ^(226)Ra standards to perform the calibration.An efficiency of(9.758±0.035)×1^(0-1) was obtained.In routine measurements,a detection limit of about 0.50 Bq L^(-1) is achieved for a 120 min counting time.To evaluate the uncertainty budget,the uncertainties of the net count rate,the efficiency,the sample amount and the decay correction factor were considered.Conclusions A method was developed for the calibration of LSC Tri-Carb 3170 TR/SL with the optimization of the PDD using a ^(226)Ra standard solution.The acquisition to obtain the plot of the variation of the events fraction in each window(alpha and beta)in function of PDD allowed to evaluate a plateau where the fraction of events was at a minimum.Afterwards,it was possible to measure the set of ^(226)Ra standards after the equilibrium with ^(222)Rn and determine the efficiency for ^(222)Rn with a detection limit of about 0.50 Bq L^(-1) in routine analyses. | Ana Rita Gomes Sérgio Dias Anabela Mourato Joao Abrantes Mário Reis | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 19 | Hospitalizations and in-hospital mortality for inflammatory bowel disease in Brazil显示文摘BACKGROUND Inflammatory bowel disease(IBD)is associated with complications,frequent hospitalizations,surgery and death.The introduction of biologic drugs into the therapeutic arsenal in the last two decades,combined with an expansion of immunosuppressant therapy,has changed IBD management and may have altered the profile of hospitalizations and in-hospital mortality(IHM)due to IBD.AIM To describe hospitalizations from 2008 to 2018 and to analyze IHM from 1998 to 2017 for IBD in Brazil.METHODS This observational,retrospective,ecological study used secondary data on hospitalizations for IBD in Brazil for 2008-2018 to describe hospitalizations and for 1998-2017 to analyze IHM.Hospitalization data were obtained from the Hospital Information System of the Brazilian Unified Health System and population data from demographic censuses.The following variables were analyzed:Number of deaths and hospitalizations,length of hospital stay,financial costs of hospitalization,sex,age,ethnicity and type of hospital admission.RESULTS There was a reduction in the number of IBD hospitalizations,from 6975 admissions in 1998 to 4113 in 2017(trend:y=-0.1682x+342.8;R^(2)=0.8197;P<0.0001).The hospitalization rate also decreased,from 3.60/100000 in 2000 to 2.17 in 2010.IHM rates varied during the 20-year period,between 2.06 in 2017 and 3.64 in 2007,and did not follow a linear trend(y=-0.0005049x+2.617;R^(2)=0,00006;P=0.9741).IHM rates also varied between regions,increasing in all but the southeast,which showed a decreasing trend(y=-0.1122x+4.427;R^(2)=0,728;P<0.0001).The Southeast region accounted for 44.29%of all hospitalizations.The Northeast region had the highest IHM rate(2.86 deaths/100 admissions),with an increasing trend(y=0.1105x+1.110;R^(2)=0.6265;P<0.0001),but the lowest hospitalization rate(1.15).The Midwest and South regions had the highest hospitalization rates(3.27 and 3.17,respectively).A higher IHM rate was observed for nonelective admissions(2.88),which accounted for 81%of IBD hospitalizations.The total cost of IBD hospitalizations in 2017 exhibited an increase of 37.5%compared to 2008.CONCLUSION There has been a notable reduction in the number of hospitalizations for IBD in Brazil over 20 years.IHM rates varied and did not follow a linear trend. | Ana Luiza Vilar Guedes Amanda Lopes Lorentz Larissa Fernandes de Almeida Rios Rios Beatriz Camara Freitas Adriano Gutemberg Neves Dias Ana Luísa Eckhard Uhlein Felipe Oliveira Vieira Neto Jobson Felipe Soares Jesus Túlio de SáNovaes Torres Raquel Rocha Vitor D Andrade Genoile Oliveira Santana | 2022 | World Journal of Gastrointestinal Pharmacology and Therapeutics2022，13，1： | 0 |
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