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| 1 | 光动力疗法治疗非小细胞肺癌显示文摘光动力疗法被越来越多地应用于治疗胸部恶性肿瘤。对于早期非小细胞肺癌(如支气管腔内肺癌)、X线检查阴性或同时性原发癌,光动疗法可作为主要治疗手段进行腔内根治性治疗。作为单一根治疗法,光动力疗法是治疗支气管镜可见≤1 cm且无软骨外浸润的肺部肿瘤的最有效方法。对于晚期非小细胞癌患者,光动力治疗可以作为综合根治疗法的一部分,用于减轻阻塞性支气管内病变,增加可手术性或缩小所需手术范围。本文对现有发表的应用光动力疗法治疗至少10例以上非小细胞肺癌病例的研究文献进行综述,提出了光动力疗法应用的治疗建议并进行了总结。 | Charles B Simone II Joseph S Friedberg Eli Glatstein James P Stevenson Daniel H Sterman Stephen M Hahn Keith A Cengel 袁光金 李金銮 朱宇熹 凌扬 | 2013 | 国际病理科学与临床杂志2013，33，3： | 3 |
| 2 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 3 | Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study显示文摘 | Daniel J Drucker John B Buse Kristin Taylor David M Kendall Michael Trautmann Dongliang Zhuang Lisa Porter | 2008 | The Lancet2008，，9645： | 2 |
| 4 | Reich characterization of a quasi-one dimensional spin -1/2 magnet which is gapless and paramagnetic for gμBH≤J and kBT《J显示文摘 | Hammar P R Stone M B Daniel H | 1999 | Phys Rev B1999，59，2： | 1 |
| 5 | Activitybased costing accounting for a market orientation 显示文摘 | Daniel J G Greg W M William B C | 1998 | Industrial Marketing Management1998，，127： | 1 |
| 6 | Mobilization and functionality of endothelial progenitor cells during antihypertensive treatment in patients with essential hypertension显示文摘 | Ralf A B Ulla M G Daniel A | 2004 | Circulation2004，110，17： | 1 |
| 7 | Combination of Two Catalytic Sites in a Novel Nanocrystalline TiO2-iron Tet- rasulfophthaloeyanine Material Provides Better Catalytic Properties 显示文摘 | Beyrhouty M Sorokin A B Daniele S | 2005 | New J Chem2005，29，： | 1 |
| 8 | Vocal response to pain in piglets显示文摘 | Daniel M W Leah A B David F | 1998 | Applied Animal Behaviour Science1998，56，2： | 1 |
| 9 | Twenty years of inten- sive fertilization and competing vegetation suppression in loblolly pine plantations: Impacts on soil C,N, and microbial biomass显示文摘 | Sami W R Daniel M Bruce B | 2010 | Soil Biology & Biochemistry2010，42，5： | 1 |
| 10 | Suppression of allergic immune responses to house dust mite (HDM) in rats exposed to 2,3,7,8-TCDD显示文摘 | Luebke R W Copeland C B Daniels M | 2001 | Toxicol Sci2001，62，1： | 1 |
| 11 | Fentanyl aug- ments the blockade of the sympathetic response to incision (MAC-BAR) produced by desflurane and isoflurane: Des- flurane and isoflurane MAC-BAR without and with fentanyl 显示文摘 | Daniel M Weiskopf R B Noorani M | 1998 | Anesthesiology1998，88，1： | 1 |
| 12 | A form of albinism in cattle is caused by a tyrosinase frameshift mutation 显示文摘 | SHEILA M S TOM G B DANIEL C C | 2004 | MammalianGenome2004，15，： | 1 |
| 13 | Toxicity studies of 1,3- dichlorobenzene in Sprague-Dawley rats显示文摘 | McCauley P T Robinson M Daniel F B | 1995 | Drug and Chemical Toxicology1995，18，23： | 1 |
| 14 | Synthesis of 2,3,5- Trichloropyridine 显示文摘 | Eginhard S Pierre M Daniel B | 2005 | Organic Process Research and Development2005，3，： | 1 |
| 15 | Incorporating observational data into the formulary decision-making process- summary of aroundtable discussion显示文摘 | ANKE-PEGGY H JOHN B W DANIEL M | 2008 | J Managed Care Pharma- cy2008，14，3： | 1 |
| 16 | Lactobacillus species isolated from the vagina: identification, hydrogen peroxide production and nonoxynol-9 resistance显示文摘 | PASCUAL L M DANIELE M B PAJARO C | 2006 | Contraception2006，73，： | 1 |
| 17 | Frontier estimation and firm-specific ineffi- ciency measures in the presence of heteroscedasticity显示文摘 | Steven B Caudill Jon M Ford and Daniel M Groppe | 1995 | Journal of Business and Economic Statistics1995，13，1： | 1 |
| 18 | Crystallization of para-Xylene in Scraped-Surface Crystallizers显示文摘 | Daniel B P James B R Hazim A M | 2001 | AICh E J2001，47，11： | 1 |
| 19 | Effects of ur- ban sewage on dissolved oxygen,dissolved inorganic and organ- ic carbon,and electrical conductivity of small streams along agradient of urbanization in the Piracicaba river basin显示文摘 | Daniel M H B Montebelo A A Bemardes M C | 2002 | Water Air and Soil Pollution2002，136，： | 1 |
| 20 | Protein method department of biochemistry university of genera显示文摘 | Stuart J E | 1997 | Genera Switzerland1997，，： | 1 |
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