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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Reinterpretation of histology of proximal colon polyps called hyperplastic in 2001显示文摘AIM: To evaluate how proximal colon polyps interpreted as hyperplastic polyps in 2001 would be interpreted by expert pathologists in 2007. METHODS: Forty consecutive proximal colon polyps ≥ 5 mm in size, removed in 2001, and originally interpreted as hyperplastic polyps by general pathologists at Indiana University, were reviewed in 2007 by 3 GI pathologists. RESULTS: The gastrointestinal (GI) pathologists interpreted 85%, 43% and 30% of the polyps as sessile serrated polyps (sessile serrated adenomas). The overall Kappa was 0.16. When diagnoses were compared in pairs, Kappa values were 0.38 and 0.25 (fair agreement) and 0.14 (slight agreement). CONCLUSION: Many polyps interpreted as hyperplastic in 2001 were considered sessile serrated lesions by GI pathologists in 2007, but there is substantial inter-observer variation amongst GI pathologists. | Omer Khalid Sofyan Radaideh Oscar W Cummings Michael J O'Brien John R Goldblum Douglas K Rex | 2009 | World Journal of Gastroenterology2009，15，30： | 3 |
| 3 | Germ cell deficient ( gcd ) mouse as a model of premature ovarian failure 显示文摘 | Duncan MK Cummings L Chada K | 1993 | Biol Reprod1993，49，2： | 1 |
| 4 | Neuropsychiatric inventory:comprehensive assessment of psychopathology in dementia显示文摘 | Cummings JL Mega M Gray K | 1994 | Neurology1994，44，11： | 1 |
| 5 | Effect of dexamethasone on the duration of interscalene nerve blocks with ropivacaine or bupivacaine显示文摘 | Cummings K C Napierkowsk D E Parra-Sanchez | 2011 | British Journal of Anaesthesia2011，107，： | 1 |
| 6 | Dielectrophoresis in Microchips Containing Arrays of Insulating Posts:Theoretical and Experimental Results显示文摘 | Cummings E B Singh A K | 2003 | Analytical Chemistry2003，75，18： | 1 |
| 7 | The complete DNA sequence of the mitochondrial genome of Podospora anserina 显示文摘 | CUMMINGS D J MCNALLY K L DOMENICO J M | 1990 | Cun~nt genetics1990，17，5： | 1 |
| 8 | Tuberculosis in children and adolescents: California, 1985 to 1995显示文摘 | Lobato MN Cummings K Will D Royce S | 1998 | Pediatr Infect Disease Journal1998，17，： | 1 |
| 9 | Oral glucose loading acutely attenuates endothelium -dependent vasodilation in healthy adults without diabetes: an effect prevented by vitamins C and E显示文摘 | TITLE L M CUMMINGS P M GIDDENS K | 2000 | J Am Coil Cradiol2000，36，7： | 1 |
| 10 | Does digestibility of meat protein help explain large-bowel cancer risk显示文摘 | SILVESTER K R CUMMINGS J H | 1995 | Nutr Cancer1995，24，： | 1 |
| 11 | Prevalence and causes of amblyopia in an adult population显示文摘 | Attebo K Mitchell P Cumming R | 1998 | Ophthalmology1998，105，1： | 1 |
| 12 | Cognitive evaluation theory: An experimental test of processes and outcomes显示文摘 | Boal K B Cummings L L | 1981 | Organizational Behavior and Human Performance1981，，28： | 1 |
| 13 | Dielectric Materials for Window Applications显示文摘 | Cumming K A Risbud S H | 2000 | Journal of Physics and Chemistry of Solids2000，61，： | 1 |
| 14 | The effect of physical activity on cognitive ftmction after stroke: a systematic review 显示文摘 | Cumming TB Tyedm K Churilov L | 2011 | IntPsychogeriatr2011，14，： | 1 |
| 15 | Gastric bypass for obesity : mechanisms of weight loss and diabetes resolution显示文摘 | Cummings D E Overduin J Foster-Schubert K E | 2004 | J Clin Endocrinol Metab2004，89，6： | 1 |
| 16 | Once-yearly zoledronic acid for treatment of post-menopausal osteoporosis显示文摘 | Black DM Delmas PD Eastell R Reid IR Boonen S Cauley JA Cosman F Lakatos P Leung PC Man Z Mautalen C Mesenbrink P Hu H Caminis J Tong K Rosario-Jansen T Krasnow J Hue TF Sellmeyer D Eriksen EF Cummings SR HORIZON Pivotal Fracture Trial | | 0，，： | 1 |
| 17 | Antimicrobial resistance trends among Salmonella isolates obtained form dairy cat- tie in the northeastern United States,2004 -2011 显示文摘 | Cummings K J Perkins GA Khatibzadeh SM | 2013 | Foodborne Pthog Dis2013，10，4： | 1 |
| 18 | Renal artery aneurysms and hypertension显示文摘 | Cummings K B Lecky J W Kaufman J J | 1973 | J Urol1973，109，： | 1 |
| 19 | Seakeeping of two ships in close proximity 显示文摘 | CUMMING D | 2003 | Ocean Engineering2003，30，： | 1 |
| 20 | Prevalence and causes of am-blyopia in an adult population显示文摘 | Mitchell P Cumming R | 1998 | Ophthalmology1998，105，1： | 1 |
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