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89篇 您的检索式:作者名="Coxon FP"
    题名 作者 年代 出处 被引量
1Stucture - activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen con- taining BPs显示文摘Dunford JE Thompson K Coxon FP 2001J Pharmacol Exp2001,296,2:1
2Structure-activity relation-ships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates显示文摘Dunford JE Thompson K Coxon FP 2001J Pharmacol Exp Ther2001,296,:1
3Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298显示文摘Coxon FP Helfrich MH Van't Hof R 2000J Bone Miner Res2000,15,8:1
4Nitrogen- containing bispbosphonates inhibit the mevalonate pathway and prevent post - translationa prenylation of GTP - bingding proteins,including Ras 显示文摘Luckman SP Hughes DE Coxon FP 1998J Bone Miner Res1998,13,:1
5Recent advances inunderstanding the mechanism of action of bisphosphonates显示文摘Coxon FP Thompson K Roqers MJ 2006Current Opinion in Pharmacology2006,6,3:1
6Protein geranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphanates and GGTI-298 显示文摘Coxon FP Helfrich MH Vant Hof RJ 2000J Bone Miner Res2000,15,8:1
7Nitrogen-containing bisphosphonates inhibit the mevalonate path way and prevent poat translational prenylation of GTP-binding proteins,including Ras显示文摘Luckman SP Hughes DE Coxon FP 1998J Bone Miner Res1998,13,:1
8The role of prenylated small GTPbinding proteins in the regulation of osteoclast function显示文摘Coxon FP Rogers MJ 2003Calcify Tissue lnt2003,72,:1
9Protein geranylation is required for osteoelast formation,function,and survival:inhibition by bisphosphanates and GGTI-298显示文摘Coxon FP Helfrich MH Vant Hof RJ 2000J Bone Miner Res2000,15,8:1
10Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates显示文摘Dunford JE Thompson K Coxon FP 2001J Pharmacol Exp Ther2001,296,:1
11Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations显示文摘Guerrini MM Sobacchi C Cassani B Abinun M Kilic SS Pangrazio A Moratto D Mazzolari E Clayton-Smith J Orchard P Coxon FP Helfrich MH Crockett JC Mellis D Vellodi A Tezcan I N otarangelo L D R ogers MJ V ezzoni P V illa A F rattini A 0,,:1
12Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent posttranslational prenylation of GTP-binding proteins,including Ras显示文摘Luckman SP Hughes DE Coxon FP 1998J Bone Miner Res1998,13,:1
13Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation:evidence from structure-activity relationships in J774 macrephages显示文摘Luckman SP Coxon FP Ibetino FH 1998J Bone Miner Res1998,13,:1
14Bone remodelling at a glance显示文摘Crockett JC Rogers MJ Coxon FP 2011J Cell Sci2011,124,7:1
15In- volvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans 显示文摘Van Wesenbeeck L Odgren PR Coxon FP 2007J Clin Invest2007,117,:1
16Stature-ac- tivity relationships for inhibition of farnesyl dipbosphate synthase in vitro and inhibition of bone recorption in vivo by nitrogen-containing bispbosphonates 显示文摘Dunford JE Thoanpson K Coxon FP 2001J Pharma- col Exp Ther2001,296,:1
17Recent advances inunderstanding the mechanism of action of bisphosphonates显示文摘Coxon FP Thompson K Rogers MJ 2006Curr Opin Pharmacol2006,6,3:1
18Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells显示文摘Coxon FP Thompson K Roelofs AJ 2008Bone2008,42,5:1
19Vesicular trafficking in osteoclasts 显示文摘Coxon FP Taylor A 2008Semin Cell Dev Biol2008,19,5:1
20Protein geranylgeranylation is required for osteoclast formation, function, and Survival: inhibition by bisphosphonates and GGTI-298 显示文摘Coxon FP Helffich MH Van't Hof R 2000J Bone Miner Res2000,15,:1
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