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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | An arbitrary Lagrangian- Eulerian computing method for all flow speeds 显示文摘 | Hirt C W Amsden A A Cook J L | 1997 | Journal of Computational Physics1997，135，2： | 1 |
| 3 | National Ignition Facility target design and fabrication显示文摘 | COOK R C KOZIOZIEMSKI B J NIKROO A | 2008 | Laser and Particle Beams2008，26，3： | 1 |
| 4 | A recombinant fowlpox virus that expresses the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus显示文摘 | BAYLISS C D PETERS R W COOK J K A | 1991 | Arch Virol1991，120，： | 1 |
| 5 | Survey of veterinary practitioners on PMWS and PDNS in the UK显示文摘 | Gresham A Cook A J C Thomson J R | 2003 | Veterinary Record2003，153，13： | 1 |
| 6 | Removal of oil,grease,and suspended solids from produced water with ceramic crossflow microfiltration显示文摘 | Chen A S C Flynn J T Cook R G | 1991 | SPE Production Engineering1991，6，2： | 1 |
| 7 | The underwater sound generated by heavy rainfall显示文摘 | Nystuen J A McGlothin C Cook M | | 0，，06： | 1 |
| 8 | An arbitrary Lagrangian Eulerian computing method forall follow speeds 显示文摘 | HIRT C W AMSDEN A A COOK J L | 1974 | J Comput Plays1974，14，3： | 1 |
| 9 | An arbitrary lagrangian-eulerian computing method for all flow speeds显示文摘 | Hirt C W Amsden A A Cook J L | 1974 | Journal of Computational Physics1974，14，3： | 1 |
| 10 | Xenon purity analysis for exo-200 via mass spectrometry 显示文摘 | Dobi A Hall C Slutsky S Yen Y R Aharmin B Auger M Barbeau P S Benitez-Medina C Breidenbach M Cleveland B Conley R Cook J Cook S Counts I Craddock W Daniels T Davis C G Davis J Devoe R Dixit M Dolinski M J Donato K Fairbank Jr W Farine J Fierlinger P Franco D Giroux G Gornea R Graham K Gratta G Green C Hagemann C Hall K Hallman D Hargrove C Herrin S Hughes M Hodgson J Juget F Karelin A Kaufman L J Kuchenkov A Kumar K Leonard D S Lutter G Mackay D Maclellan R Marino M Mong B Montero Diez M Morgan P MUller A R Neilson R Odian A Oullivan K Piepke A Pocar A Prescott C Y Pushkin K Rivas A Rollin E Rowson P C Sabourov A Sinclair D Skarpaas K Stekhanov V Strickland V Swift M Twelker K Vuilleumier J L Vuilleumier J M Weber M Wichoski U Wodin J Wright J D Yang L | 2012 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators Spectrometers Detectors and Associated Equipment2012，675，： | 1 |
| 11 | Motilin, a gastric motor activity-stimulating polypeptide 显示文摘 | BROWN J C COOK M A DRYBRUGH J R | 1972 | Gastroenterology1972，62，3： | 1 |
| 12 | An arbitrary Lagrangian-Eulerian computing method for all flow speeds显示文摘 | Hirt C W Amsden A A Cook J L | 1974 | J Computational Physics1974，14，： | 1 |
| 13 | Statistical approaches to group sequential monitoring of postmarket safety surveillance da- ta: Current state of the art for use in the mini-sentinel pilot 显示文摘 | Cook A J Tiwari R C Wellman R D | 2012 | Pharmacoepidemiol Drug Saf2012，，： | 1 |
| 14 | Bed mixing and heat transfer in a batch loaded rotary kiln显示文摘 | LEGER C B COOK C A CUNDY V A STERLIMG A M DENG X LIGHTY J S | | 0，，02： | 1 |
| 15 | Are oxidative mechanisms primary in ethanol induced Purkiuje neuron death of the neonatal rat? 显示文摘 | Pierce D R Cook C C Hinson J A | 2006 | Neurosci Lett2006，400，12： | 1 |
| 16 | Brief reports : a program to reduce use of physical restraint in psychiatric inpatient facilities显示文摘 | Jonikas J A Cook J A Rosen C | 2004 | Psy- chiatrics Service2004，55，7： | 1 |
| 17 | A recombinant fowlpox virus that expresss the VP2 antigen of infectious bursal disease virus induces protection against mortality caused by the virus 显示文摘 | Bayliss C D Peters R W Cook J K A | 1991 | Arch Virol1991，120，： | 1 |
| 18 | Radiation sensitisation by nitric oxide releasing agents 显示文摘 | Mitchell J B Cook J A Krishna M C | 1996 | Br J Cancer Suppl1996，27，： | 1 |
| 19 | An arbitrary Lagrangian-Eulerian computing method for all flow speeds显示文摘 | HIRT C W AMSDEN A A COOK J L | 1974 | Journal of Computational Physics1974，14，3： | 1 |
| 20 | Behavior and design of single anchors under tensile load in uncracked concrete显示文摘 | COOK R A KUCHS J FUCHS R C | 1998 | Structural Journal1998，95，1： | 1 |
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