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| 1 | CVD growth of fingerprint-like patterned 3D graphene film for an ultrasensitive pressure sensor显示文摘与便携设备的快速的发展,有高敏感和宽可使用的范围的灵活压力传感器高度被需要。在自然,有许多改编得好的结构,通过自然选择开发,它为 biomimetic 材料或设备的设计鼓舞了我们。特别地,在许多表皮的山脉放大外部刺激的地方,人的指尖皮肤可能是一个好例子为高度敏感的传感器模仿。在这个工作,基于唯一的化学蒸汽免职( CVD )种模仿指尖皮肤的形态学的 3D graphene 电影,我们制作了察觉到膜的灵活压力,它同时显示出 110 的高敏感( kPa )为 0-0.2 kPa 和宽可使用的压力范围(多达 75 kPa )的1。从自然叶子塑造的层次结构化的 PDMS 电影为 graphene 电影被用作支持的有弹性的电影,它也贡献压力传感器的优异表演。压力传感器显示出低察觉限制(0.2 Pa ) ,快反应(< 30 ms ) ,并且为超过 10,000 的优秀稳定性装载 / 卸掉周期。把特征基于这些,我们在检测微小的对象,声音,和人的生理的信号演示了它的应用程序,为监视的健康和人 / 机器在便携电子学显示出它的潜力连接。 | Kailun Xia Chunya Wang Muqiang Jian Qi Wang Yingying Zhang | 2018 | Nano Research2018，11，2： | 13 |
| 2 | Superelastic wire-shaped supercapacitor sustaining 850% tensile strain based on carbon nanotube@graphene fiber显示文摘 | Huimin Wang Chunya Wang Muqiang Jian Qi Wang Kailun Xia Zhe Yin Mingchao Zhang Xiaoping Liang Yingying Zhang | 2018 | Nano Research2018，11，5： | 6 |
| 3 | Traditional Chinese Medicine for the treatment of influenza: a systematic review and Meta-analysis of randomized controlled trials显示文摘OBJECTIVE: To justify the clinical use of Traditional Chinese Medicine(TCM) in the treatment of influenza.METHODS: MEDLINE, EMBASE, Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, China Science and Technology Journal Database, Wanfang Database and the Cochrane Database of Systematic Reviews were searched from thedate of inception until January 1,2013, for the literature on treatment of influenza with TCM.RESULTS: A total of 7 randomized controlled trials were identified and reviewed. Of these trials, 2 compared a(modified) prescription of TCM with oseltamivir and 5 compared a patent traditional Chinese drug with oseltamivir. Based on the Meta-analysis,compared to oseltamivir, the(modified) prescription had similar effect in defervescence [WMD=5.66, 95% CI(﹣32.02, 43.35), P=0.77] and viral shedding [WMD=﹣ 6.21, 95% CI(﹣84.19, 71.76), P=0.88], and the patent traditional Chinese drug also had similar effect in viral shedding [WMD=﹣ 0.24,95% CI(﹣4.79, 4.31), P=0.92] but more effective in defervescence [WMD=﹣4.65, 95%CI(﹣8.91, ﹣0.38),P=0.03].CONCLUSION: TCM has potential positive effects in the treatment of influenza. | Chunya Wang Hao Wang Xinying Liu Dongping Xu Yiping Tang Ping Luo | 2014 | Journal of Traditional Chinese Medicine2014，34，5： | 5 |
| 4 | Comparison of rescue strategies in lamivudine-resistant patients with chronic hepatitis B显示文摘 | Pan Zhao Chunya Wang LiLi Huang Dongping Xu Tanshi Li | 2012 | Antiviral Research2012，，2： | 2 |
| 5 | Research on the se- mantic-based co -word analysis 显示文摘 | Wang Zhengyi Li Gang Li Chunya | 2012 | Seientometries2012，90，3： | 1 |
| 6 | Development of a parathion sensor based on molecularly imprinted nano-TiO2 self-assembled film electrode 显示文摘 | Li Chunya WangChangfa Wang Chenghang | 2006 | Sensors and Actuators B2006，117，1： | 1 |
| 7 | Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer显示文摘Background:Immune checkpoint inhibitors(ICIs)targeting programmed cell death protein 1(PD-1)and programmed death-ligand 1(PD-L1)have shown a moderate response in colorectal cancer(CRC)with deficient mismatch repair(dMMR)functions and poor response in patients with proficientMMR(pMMR).pMMRtumors are generally immunogenically“cold”,emphasizing combination strategies to turn the“cold”tumor“hot”to enhance the efficacy of ICIs.ATR inhibitors(ATRi)have been proven to cooperate with radiation to promote antitumor immunity,but it is unclear whether ATRi could facilitate the efficacy of IR and ICI combinations in CRCs.This study aimed to investigate the efficacy of combining ATRi,irradiation(IR),and anti-PD-L1 antibodies in CRC mouse models with different microsatellite statuses.Methods:The efficacy of combining ATRi,IR,and anti-PD-L1 antibodies was evaluated in CRC tumors.The tumor microenvironment and transcriptome signatures were investigated under different treatment regimens.The mechanisms were explored via cell viability assay,flow cytometry,immunofluorescence,immunoblotting,co-immunoprecipitation,and real-time quantitative PCR in multiple murine and human CRC cell lines.Results:Combining ATRi berzosertib and IR enhanced CD8+T cell infiltration and enhanced the efficacy of anti-PD-L1 therapy in mouse CRC models with different microsatellite statuses.The mechanistic study demonstrated that IR+ATRi could activate both the canonical cGAS-STING-pTBK1/pIRF3 axis by increasing cytosolic double-stranded DNA levels and the non-canonical STING signaling by attenuating SHP1-mediated inhibition of the TRAF6-STINGp65 axis,via promoting SUMOylation of SHP1 at lysine 127.By boosting the STING signaling,IR+ATRi induced type I interferon-related gene expression and strong innate immune activation and reinvigorated the cold tumor microenvironment,thus facilitating immunotherapy.Conclusions:The combination of ATRi and IR could facilitate anti-PD-L1 therapy by promoting STING signaling in CRC models with different microsatellite statuses.The new combination strategy raised by our study isworth investigating in the management of CRC. | Chaofan Liu Xi Wang Wan Qin Jingyao Tu Chunya Li Weiheng Zhao Li Ma Bo Liu Hong Qiu Xianglin Yuan | 2023 | Cancer Communications2023，43，4： | 1 |
| 8 | Electrocatalytic oxidation of nitric oxide at nano-TiO2/Nafion composite film modified glassy carbon electrode显示文摘 | WANG Yazhen LI Chunya HU Shengshui | 2006 | J Solid State Electrochem2006，10，6： | 1 |
| 9 | Research on the semantic- based co-word analysis 显示文摘 | Wang Zhongyi Li Gang Li Chunya | 2012 | Scientometrics2012，90，3： | 1 |
| 10 | Covalent Modification of Glassy Carbon Electrode with L-Cysteine for the Determination of Acetaminophen 显示文摘 | Chenghang Wang Chunya Li Fang Wang | 2006 | Microchim Acta2006，，： | 1 |
| 11 | Electrochemical sensor for the determination of parathion based on p-tert-butylcalix arene-1,4-crown-4 sol-gel film and its characterization by electrochemical methods 显示文摘 | Li Chunya Wang Changfa Zhang Yangyang | 2005 | Sensors and Actuators B2005，107，1： | 1 |
| 12 | Electrocatalytic oxidation of nitric oxide at nano -TiO2/Nafion composite film modified glassy carbon electrode显示文摘 | WANG Yazhen LI Chunya HU Shengshui | 2006 | J Solid State Electrochem2006，10，6： | 1 |
| 13 | Construction of a novel molecularly imprinted sensor for the determination of O, O-dimethyl-( 2,4-dichlorophenoxyacetoxyl ) ( 3'-nitrophenyl ) methinephosphonate 显示文摘 | Li Chunya Wang Changfa Wang Chenghang | 2005 | Analytiea Chimica Acta2005，545，2： | 1 |
| 14 | Phosphonate electrochemical recognition by molecularly imprinted deposited film 显示文摘 | Wang Chenghang Li Chunya Wang Fang | 2006 | Applied Surface Science2006，253，4： | 1 |
| 15 | Voltammetric sensor for tinidazole based on poly(carmine)film modified electrode and its application显示文摘 | Wang Chenghang Wang Fang Li Chunya | 2007 | Dyes and Pigments2007，75，1： | 1 |
| 16 | Fluorescent sensor for selective determination of copper ion based on N-acetyl- l -cysteine capped CdHgSe quantum dots显示文摘 | Qingqing Wang Xiangyang Yu Guoqing Zhan Chunya Li | 2014 | Biosensors and Bioelectronics2014，，： | 1 |
| 17 | A reduced graphene oxide–nanoporous magnetic oxide iron hybrid as an improved anode material for lithium ion batteries显示文摘 | Xianjun Zhu Wenyan Wu Zhen Liu Liang Li Jing Hu Huaili Dai Lei Ding Kun Zhou Chunya Wang Xuegang Song | 2013 | Electrochimica Acta2013，，： | 1 |
| 18 | Causes and outcomes of acute liver failure in china显示文摘 | Pan Zhao Chunya Wang Weiwei Liu | 2013 | PLoS One2013，8，80： | 1 |
| 19 | A novel amperometric sensor and chromatographic detector for determination of parathion显示文摘 | Li Chunya Wang Changfa Ma Yong | 2005 | Anal Bioanal Chem2005，381，： | 1 |
| 20 | Nuclear PKM2 expression predicts poor prognosis in patients with esophageal squamous cell carcinoma显示文摘 | Xuelin Zhang Chengzhi He Chunya He Baofu Chen Yanxia Liu Min Kong Chunguo Wang Lizhong Lin Yan Dong Haihui Sheng | 2013 | Pathology - Research and Practice2013，，： | 1 |
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