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| 1 | Isolation and NMR spectral as- signments of steviolbioside and stevioside 显示文摘 | Chaturvedula V S P Prakash I | 2011 | International Journal of Research in Ayurveda & Pharmacy2011，2，4： | 1 |
| 2 | Cytotoxic diterpenes from Cassipourea madagascariensis from the Madagascar Rainforest显示文摘 | Prakash Chaturvedula V S Norris A Miller J S | 2006 | J Nat Prod2006，69，2： | 1 |
| 3 | Long-term and non-invasive in vivo tracking of DiD dye-labeled human hepatic progenitors in chronic liver disease models显示文摘BACKGROUND Chronic liver diseases(CLD)are the major public health burden due to the continuous increasing rate of global morbidity and mortality.The inherent limitations of organ transplantation have led to the development of stem cell-based therapy as a supportive and promising therapeutic option.However,identifying the fate of transplanted cells in vivo represents a crucial obstacle.AIM To evaluate the potential applicability of DiD dye as a cell labeling agent for longterm,and non-invasive in vivo tracking of transplanted cells in the liver.METHODS Magnetically sorted,epithelial cell adhesion molecule positive(1×106 cells/mL)fetal hepatic progenitor cells were labeled with DiD dye and transplanted into the livers of CLD-severe combined immunodeficiency(SCID)mice.Near-infrared(NIR)imaging was performed for in vivo tracking of the DiD-labeled transplanted cells along with colocalization of hepatic markers for up to 80 d.The existence of human cells within mouse livers was identified using Alu polymerase chain reaction and sequencing.RESULTS NIR fluorescence imaging of CLD-SCID mice showed a positive fluorescence signal of DiD at days 7,15,30,45,60,and 80 post-transplantation.Furthermore,positive staining of cytokeratin,c-Met,and albumin colocalizing with DiD fluorescence clearly demonstrated that the fluorescent signal of hepatic markers emerged from the DiD-labeled transplanted cells.Recovery of liver function was also observed with serum levels of glutamic-oxaloacetic transaminase,glutamate-pyruvate transaminase,and bilirubin.The detection of human-specific Alu sequence from the transplanted mouse livers provided evidence for the survival of transplanted cells at day 80.CONCLUSION DiD-labeling is promising for long-term and non-invasive in vivo cell tracking,and understanding the regenerative mechanisms incurred by the transplanted cells. | Chaturvedula Tripura Srinivas Gunda Sandeep Kumar Vishwakarma Avinash Raj Thatipalli Jedy Jose Mahesh Kumar Jerald Aleem Ahmed Khan Gopal Pande | 2022 | World Journal of Hepatology2022，14，10： | 1 |
| 4 | New lupane trierpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase β显示文摘 | Chaturvedula P V S Zhou B N Gao Z J | 2004 | Bioorganic & Medicinal2004，12，23： | 1 |
| 5 | New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase beta显示文摘 | Zhou BN Gao Z | 2004 | Bio org Med Chem2004，12，23： | 1 |
| 6 | Accident Proneness of Pilots in Indian Air Force:An Empirical Analysis Through selection criteria 显示文摘 | Rani EK Chaturvedula S | 2009 | Indian Journal of Aerospace Medicine2009，53，1： | 1 |
| 7 | Stability of rebaudioside A under acidic conditions and its degradation products显示文摘 | PRAKASH I CLOS J F CHATURVEDULA V S P | 2012 | Food Research International2012，48，1： | 1 |
| 8 | A new diterpene glyco-side from Stevia rebaudiana显示文摘 | Chaturvedula V S P Prakash I | 2011 | Molecules2011，16，： | 1 |
| 9 | Minor diter-penoid glycosides from the leaves of Stevia rebaudiana显示文摘 | Chaturvedula V S P Clo J F Rhea J | 2011 | Phytochemistry Letters2011，4，： | 1 |
| 10 | Accident Proneness of Pilots in Indian Air Force:An Empirical Analysis Through Selection Criteria显示文摘 | E Kalpana Rani Chaturvedula S | 2009 | Indian Journal of Aerospace Medicine2009，53，1： | 1 |
| 11 | New norditerpenoids and a diterpenoid from a sponge that inhibit the lyase activity of DNA polymerase beta 显示文摘 | CHATURVEDULA V S P GAO Z J THOMAS S H | 2004 | Tetrahedron2004，60，： | 1 |
| 12 | Bioengineered functional humanized livers: An emerging supportive modality to bridge the gap of organ transplantation for management of end-stage liver diseases显示文摘End stage liver diseases(ESLD) represent a major, neglected global public health crisis which requires an urgent action towards finding a proper cure. Orthotropic liver transplantation has been the only definitive treatment modality for ESLD. However, shortage of donor organs, timely unavailability, post-surgery related complications and financial burden on the patients limits the number of patients receiving the transplants. Since last two decades cell-based therapies have revolutionized the field of organ/tissue regeneration. However providing an alternative organ source to address the donor liver shortage still poses potential challenges. The developments made in this direction provide useful futuristic approaches, which could be translated into preclinical and clinical settings targeting appropriate app-lications in specific disease conditions. Earlier studieshave demonstrated the applicability of this particularapproach to generate functional organ in rodent systemby connecting them with portal and hepatic circulatorynetworks. However, such strategy requires very highlevel of surgical expertise and also poses the technicaland financial questions towards its future applicability.Hence, alternative sites for generating secondary organsare being tested in several types of disease conditions.Among different sites, omentum has been proved tobe more appropriate site for implanting several kindsof functional tissue constructs without eliciting muchimmunological response. Hence, omentum may be considered as better site for transplanting humanized bioengineered ex vivo generated livers, thereby creatinga secondary organ at intra-omental site. However, theexpertise for generating such bioengineered organs arelimited and only very few centres are involved for investigating the potential use of such implants in clinicalpractice due to gap between the clinical transplantsurgeons and basic scientists working on the conceptevolution. Herein we discuss the recent advances andchallenges to create functional secondary organs through intraomental transplantation of ex vivo generated bioengineered humanized livers and their furtherapplication in the management of ESLD as a supportivebridge for organ transplantation. | Sandeep Kumar Vishwakarma Chandrakala Lakkireddy Avinash Bardia Syed Ameer Basha Paspala Chaturvedula Tripura Md Aejaz Habeeb Aleem Ahmed Khan | 2018 | World Journal of Hepatology2018，10，11： | 1 |
| 13 | In vivo iontophoretic delivery and pharmacokinetics of salmon calcitonin显示文摘 | Chaturvedula A Joshi D P Anderson C | 2005 | Int J Pharm2005，297，2： | 1 |
| 14 | A review of 93 cases of ruptured uterus over a period of 2 years in a tertiary care hospital in South India显示文摘 | Veena P Habeebul ah S Chaturvedula L | | 0，，03： | 1 |
| 15 | Minor diterpenoids glycosides from the leaves of Stevia rebaudiana显示文摘 | Chaturvedula VSP Clos JF Rhea J Milanowski D Mocek U DuBois GE Prakash I | | 0，，03： | 1 |
| 16 | New cytotoxic lupane triterpenoids from the twigs of Coussarea paniculata显示文摘 | Chaturvedula Prakash V S Schilling Jennifer K Johnson Randall K | 2003 | J Nat Prod2003，66，： | 1 |
| 17 | New lupane trierpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase显示文摘 | CHATURVEDULA P V S ZHOU B N GAO Z J | 2004 | Bioorganic & Medicinal2004，，12： | 1 |
| 18 | Ethyl methanesulfonate mutagenesis - enhanced mineral phosphate solubilization by groundnut - associated Serratia marcestens GPS - 5 显示文摘 | Chaturvedula Tripura Burla Sashidhar Appa Rao Podile | 2007 | Current Microbiology2007，54，： | 1 |
| 19 | A new ursane triter- pene from Monochaetum vulcanicum that inhibits DNA polymer- ase 显示文摘 | Chaturvedula VS Gao Z Jones SH | 2004 | J Nat Prod2004，67，5： | 1 |
| 20 | New lupane triterpenoids from Solidago canadensis that inhibit the lyase activity of DNA polymerase β显示文摘 | Chaturvedula V S P Zhou B N Gao Z J | 2004 | Bioorganic & Medicinal Chemistry2004，12，： | 1 |
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