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| 1 | Agricultural Risk Factors Influence Microbial Ecology in Honghu Lake显示文摘Agricultural activities, including stock-farming, planting industry, and fish aquaculture,can affect the physicochemical and biological characters of freshwater lakes. However, the effects of pollution producing by agricultural activities on microbial ecosystem of lakes remain unclear.Hence, in this work, we selected Honghu Lake as a typical lake that is influenced by agriculture activities. We collected water and sediment samples from 18 sites, which span a wide range of areas from impacted and less-impacted areas. We performed a geospatial analysis on the composition of microbial communities associated with physicochemical properties and antibiotic pollution of samples. The co-occurrence networks of water and sediment were also built and analyzed. Our results showed that the microbial communities of impacted and less-impacted samples of water were largely driven by the concentrations of TN, TP, NO_3^--N, and NO_2^--N, while those of sediment were affected by the concentrations of Sed-OM and Sed-TN. Antibiotics have also played important roles in shaping these microbial communities: the concentrations of oxytetracycline and tetracycline clearly reflected the variance in taxonomic diversity and predicted functional diversity between impacted and less-impacted sites in water and sediment samples, respectively. Furthermore, for samples from both water and sediment, large differences of network topology structures between impacted and less-impacted were also observed. Our results provide compelling evidence that the microbial community can be used as a sentinel of eutrophication and antibiotics pollution risk associated with agricultural activity; and that proper monitoring of this environment is vital to maintain a sustainable environment in Honghu Lake. | Maozhen Han Melissa Dsouza Chunyu Zhou Hongjun Li Junqian Zhang Chaoyun Chen Qi Yao Chaofang Zhong Hao Zhou Jack A Gilbert Zhi Wang Kang Ning | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 3 |
| 2 | Improved plasmid-based recovery of coxsackievirus A16 infectious clone driven by human RNA polymerase I promoter显示文摘Dear Editor,Coxsackievirus A16(CA16)is one of the major viral pathogens associated with hand,foot,and mouth disease.CA16 belongs to the Enterovirus genus of the Picornaviridae family and possesses a single-stranded positivesense RNA genome(Mao et al.,2014).Reverse genetics is an important tool for CA16 research.Previously,a reverse genetics T7 polymerase-based system was de- | xiaoli wang chaoyun shen tan chen ke lan zhong huang yunfang zhang qingwei liu | 2016 | Virologica Sinica2016，31，4： | 2 |
| 3 | Impossible meet-in-the-middle fault analysis on the LED lightweight cipher in VANETs显示文摘With the expansion of wireless technology, vehicular ad-hoc networks(VANETs) are emerging as a promising approach for realizing smart cities and addressing many serious traffic problems, such as road safety, convenience, and efficiency. To avoid any possible rancorous attacks, employing lightweight ciphers is most effective for implementing encryption/decryption, message authentication, and digital signatures for the security of the VANETs. Light encryption device(LED) is a lightweight block cipher with two basic keysize variants: LED-64 and LED-128. Since its inception, many fault analysis techniques have focused on provoking faults in the last four rounds to derive the 64-bit and 128-bit secret keys. It is vital to investigate whether injecting faults into a prior round enables breakage of the LED. This study presents a novel impossible meet-in-the-middle fault analysis on a prior round. A detailed analysis of the expected number of faults is used to uniquely determine the secret key. It is based on the propagation of truncated differentials and is surprisingly reminiscent of the computation of the complexity of a rectangle attack. It shows that the impossible meet-in-the-middle fault analysis could successfully break the LED by fault injections. | Wei LI Vincent RIJMEN Zhi TAO Qingju WANG Hua CHEN Yunwen LIU Chaoyun LI Ya LIU | 2018 | Science China(Information Sciences)2018，61，3： | 1 |
| 4 | Facile synthesis of mesoporous zeolite Y with improved catalytic performance for heavy oil fl uid catalytic cracking显示文摘 | Jin Junsu Peng Chaoyun Wang Jiujiang | 2014 | Ind Eng Chem Res2014，53，8： | 1 |
| 5 | Neuroprotective effects of safflor yellow B on brain ischemic injury显示文摘 | WANG Chaoyun ZHANG Dalei LI Guisheng | | 0，，： | 1 |
| 6 | Strain-Insensitive Hierarchically Structured Stretchable Microstrip Antennas for Robust Wireless Communication显示文摘As the key component of wireless data transmission and powering,stretchable antennas play an indispensable role in flexible/stretchable electronics.However,they often suffer from frequency detuning upon mechanical deformations;thus,their applications are limited to wireless sensing with wireless transmission capabilities remaining elusive.Here,a hierarchically structured stretchable microstrip antenna with meshed patterns arranged in an arched shape showcases tunable resonance frequency upon deformations with improved overall stretchability.The almost unchanged resonance frequency during deformations enables robust on-body wireless communication and RF energy harvesting,whereas the rapid changing resonance frequency with deformations allows for wireless sensing.The proposed stretchable microstrip antenna was demonstrated to communicate wirelessly with a transmitter(input power of−3 dBm)efficiently(i.e.,the receiving power higher than−100 dBm over a distance of 100 m)on human bodies even upon 25%stretching.The flexibility in structural engineering combined with the coupled mechanical-electromagnetic simulations,provides a versatile engineering toolkit to design stretchable microstrip antennas and other potential wireless devices for stretchable electronics. | Jia Zhu Senhao Zhang Ning Yi Chaoyun Song Donghai Qiu Zhihui Hu Bowen Li Chenghao Xing Hongbo Yang Qing Wang Huanyu Cheng | 2021 | Nano-Micro Letters2021，13，8： | 1 |
| 7 | Facile synthesis of mesoporous zeolite Y with improved catalytic performance for heavy oil fluid catalytic cracking 显示文摘 | Jin Junsu Peng Chaoyun Wang Jiujiang | 2014 | Industrial & Engineering Chemistry Research2014，53，8： | 1 |
| 8 | Role of Elevated Thrombospondin-1 in Kainic Acid-Induced Status Epilepticus显示文摘Previous studies have suggested that thrombospondin-1(TSP-1) regulates the transforming growth factor beta 1(TGF-b1)/phosphorylated Smad2/3(p Smad2/3) pathway. Moreover, TSP-1 is closely associated with epilepsy. However, the role of the TSP-1-regulated TGFb1/p Smad2/3 pathway in seizures remains unclear. In this study, changes in this pathway were assessed following kainic acid(KA)-induced status epilepticus(SE) in rats.The results showed that increases in the TSP-1/TGF-b1/p Smad2/3 levels spatially and temporally matched the increases in glial fibrillary acidic protein(GFAP)/chondroitin sulfate(CS56) levels following KA administration.Inhibition of TSP-1 expression by small interfering RNA or inhibition of TGF-b1 activation with a Leu-Ser-Lys-Leu peptide significantly reduced the severity of KA-induced acute seizures. These anti-seizure effects were accompanied by decreased GFAP/CS56 expression and Smad2/3 phosphorylation. Moreover, inhibiting Smad2/3 phosphorylation with ponatinib or SIS3 also significantly reduced seizure severity, alongside reducing GFAP/CS56 immunoreactivity. These results suggest that the TSP-1-regulated TGF-b1/p Smad2/3 pathway plays a key role in KA-induced SE and astrogliosis, and that inhibiting this pathway may be a potential anti-seizure strategy. | Yurong Zhang Mengdi Zhang Wei Zhu Xiaohong Pan Qiaoyun Wang Xue Gao Chaoyun Wang Xiuli Zhang Yuxia Liu Shucui Li Hongliu Sun | 2020 | Neuroscience Bulletin2020，36，3： | 1 |
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