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| 1 | Immunomodulatory effects of polysaccharides from edible fungus:a review显示文摘The polysaccharides from edible fungus showed many kinds of biological activities,including anti-tumor,immunomodulatory,anti-inflammatory,anti-diabetes,improving functional constipation activities.In particular,the immunomodulatory effects have been paid more and more attention by scholars,but there was no systematic introduction of their immunomodulatory mechanism.So,this review introduced the immunomodulatory effects and mechanism of edible fungus polysaccharides in recent years,and then the relationships between structure and immunomodulatory effect were also discussed. | Zhenghua Yin Zhenhua Liang Changqin Li Jinmei Wang Changyang Ma Wenyi Kang | 2021 | Food Science and Human Wellness2021，10，4： | 12 |
| 2 | A critical review on chemical constituents and pharmacological effects of Lilium显示文摘Genus Lilium is famous for edible and medicinal function which is related to its chemical constituents and pharmacological effects.Chemical researches showed that genus Lilium genus mainly contains steroidal saponins,polysaccharides,alkaloids and flavonoids.Pharmacological effects of Lilium include anti-tumor,hypoglycemic,antibacterial,anti-oxidation,anti-depression and anti-inflammatory.This paper summarized chemical constituents and pharmacological effects of Lilium. | Pengyu Wang Jian Li Fatma Alzahra K.Attia Wenyi Kang Jinfeng Wei Zhenhua Liu Changqin Li | 2019 | Food Science and Human Wellness2019，8，4： | 6 |
| 3 | Spectrum-effect relationship of immunologic activity of Ganoderma lucidum by UPLC-MS/MS and component knock-out method显示文摘This study was designed to elucidate the immunoregulation of Ganoderma lucidum.HPLC fingerprint and spectrum-effect relationship of G.lucidum were established to predict the active compounds and BP neural network model was established to predict the efficacy.Then the target compounds were identified by high resolution mass spectrometry.The results indicated that there are both enhanced immunity and immunosuppressive components in G.lucidum.BP neural network was trained with the common peak area and immune effi cacy index of G.lucidum fi ngerprint as samples,and a combined evaluation system of G.lucidum fi ngerprint effi cacy was established.The correlation coeffi cient R of BP network model was 0.98643,and the error of pharmacodynamic prediction results was in the ideal range.Eight compounds were identifi ed by high resolution mass spectrometry.The compounds related to immune activity in G.lucidum were determined in this study. | Changqin Li Yiping Cui Jie Lu Lijun Meng Changyang Ma Zhenhua Liu Yan Zhang Wenyi Kang | 2021 | Food Science and Human Wellness2021，10，3： | 6 |
| 4 | Antioxidant activity and total phenolic content of essential oils and extracts of sweet basil(Ocimum basilicum L.)plants显示文摘The present study was conducted to evaluate the chemical composition and antioxidant activity of the essential oils and ethanol extracts of Ocimum basilicum L.obtained from Assiut,Minia and BeniSuef of Egypt.The major constituents of sweet basil essential oils from three locations were linalool,estragole,methyl cinnamate,bicyclosesquiphellandrene,eucalyptol,-bergamotene,eugenol,-cadinene and germacrene D by the method of GC–MS.The relative concentration of these compounds varies.The basil extracts contained appreciable levels of total phenolic contents and exhibited good DPPH radical scavenging capacity higher than that of essential oils.The highest TPC(82.45 mg PE/g)and maximum radical scavenging activity with IC50 value(1.29 mg/mL)was obtained from Minia basil extract.High correlation between antioxidant activity and total phenolic contents of basil extracts was observed.High variation in free radical scavenging activity of essential oils was found.The essential oil from Minia basil showed high activity in DPPH radical scavenging with IC50(11.23 mg/mL)and contained the highest content of phenolic(41.3 mg PE/g).On contrary,low correlation between antioxidant activity and total phenolic contents of basil essential oils from different locations.The results of the present investigation demonstrated significant variations in the antioxidant activities of sweet basil essential oils and extracts from Egypt. | Adel F.Ahmed Fatma A.K.Attia Zhenhua Liu Changqin Li Jinfeng Wei Wenyi Kang | 2019 | Food Science and Human Wellness2019，8，3： | 4 |
| 5 | Characterization of impurities in cefpodoxime proxetil using LC–MS^(n)显示文摘Reversed-phase liquid chromatography coupled with electrospray ionization tandem mass spectrometry(ESI-MS/MS)was used to characterize impurities in cefpodoxime proxetil,an ester-modified prodrug.Based on the mechanisms by which cephalosporins are degraded,stress tests were designed and performed.The bulk material and capsule were eluted through a C18 column with formic acid–methanol–water as the mobile phase.In total,15 impurities were characterized in commercial samples,including 7 known impurities and 8 new impurities.The structures of these unknown compounds were deduced via comparison with the fragmentation patterns of cefpodoxime proxetil.Data from this systematic study will help improve the safety and quality of cefpodoxime proxetil. | Jin Li Dousheng Zhang Changqin Hu | 2014 | Acta Pharmaceutica Sinica B2014，4，4： | 3 |
| 6 | Development of a Method for the Detection of-Laetamases in Milk Samples显示文摘 | JINGYUN LI CHANGQIN HU | 2007 | CUI ET AL:JOURNAL OF AOAC INTERNATIONAL2007，90，4： | 1 |
| 7 | Simple and Sensitive Assay for Nucleic Acids Using Their Quenching Effect on the Chemiluminescence Reaction Between Luminol and Hydrogen Peroxide withManganese-Tetrasulfonatophthalocyanine as a new Catalyst显示文摘 | Yongxin Li Changqin Zhu Lun Wang Donghui Li Jingou Xu | 2003 | Mikrochimica Acta2003，143，1： | 1 |
| 8 | Isolation and characterization of Streptococcus gallolyticus subsp. pasteurianus causing meningitis in ducklings显示文摘 | Meixia Li Changqin Gu Wanpo Zhang Shuang Li Jiren Liu Chong Qin Jingliang Su Guofu Cheng Xueying Hu | 2012 | Veterinary Microbiology2012，，： | 1 |
| 9 | Procoagulant constituents from Cordyceps militaris显示文摘Cordyceps militaris,belongs to Clavicipitaceae family,was investigated for its chemical compounds,and six compounds were isolated and purified by silica gel column chromatography,Sephadex LH-20 and recrystallization,and their structures were elucidated by spectral techniques and physicochemical properties as ergosterol(1),adenosine(2),cordycepin(3),ergosterol peroxide(4),tetracosanoic acid 2,3-dihydroxypropylester(5),mannitol(6).Procoagulant activity was screened by assaying the activated partial thromboplastin time(APTT),prothrombin time(PT),thrombin time(TT)and fibrinogen(FIB)in vitro.The results indicated that ergosterol,adenosine,cordycepin,ergosterol peroxide and mannitol showed strong procoagulant activity. | Juanjuan Zhang Wei Zhang Zhenhua Yin Changqin Li Wenyi Kang | 2018 | Food Science and Human Wellness2018，7，4： | 1 |
| 10 | Development of a method for the detection of beta- lactamases in milk samples 显示文摘 | CUI Shenghui LI Jingyun HU Changqin | 2007 | J AOAC Int2007，90，： | 1 |
| 11 | Development of a method for the detection of β-lactamase in milk samples显示文摘 | CUI Shenghui LI Jingyun HU Changqin | 2007 | Journal of AOAC International2007，90，4： | 1 |
| 12 | Simple and sensitive assay for nucleic acids by use of the resonancelight-scattering technique with copper phthalocyanine tetrasulfonic acid in the presence ofcetyltrimethylammonium bromide显示文摘 | Yongxin Li Yuqin Wu Jinlong Chen Changqin Zhu Lun Wang Sujuang Zhuo Danhua Zhao | 2003 | Analytical and Bioanalytical Chemistry2003，377，4： | 1 |
| 13 | A comprehensive review on mechanism of natural products against Staphylococcus aureus显示文摘The abuse of antibiotics seriously threatens the therapeutic effect.Natural products from plants,antimicrobial peptides and micro-organisms have antibacterial activity against Staphylococcus aureus.The mechanism of natural products reported in recent years on S.aureus includes six types,which are the acting on bacterial cell wall,cytomembrane,metabolic pathway,protein,nucleic acid,biofilm and quorum sensing system to achieve antibacterial effect.This article summarized the mechanism of natural products reported in recent years on S.aureus.It is found that the natural products acting on cell wall or cell wall synthesis pathway key enzymes are relatively safe and highly selective.It has the prospect of developing into medicine and provides the clue to investigate and utilize natural products in antibacterial activity. | Yingying Zhao Jinfeng Wei Changqin Li Adel F.Ahmed Zhenhua Liu Changyang Ma | 2022 | Journal of Future Foods2022，2，1： | 0 |
| 14 | The quality control and hypoglycemic effect of Cinnamomi Cortex aqueous extract显示文摘Cinnamomi Cortex was a material as medicinal and edible resources and it has been demonstrated that Cinnamomi Cortex aqueous extract(CCAE)possess hypoglycemic effect,but there were no active compounds identified as quality standard of CCAE to be used in the investigate of hypoglycemic activity.Hence,in this study,the quality standard and the hypoglycemic effect of CCAE were investigated.Cinnamaldehyde and coumarin as the quality control in CCAE were analyzed by high performance liquid chromatography(HPLC)method.The results showed that the average yield of extraction was 10.06%.The concentration of coumarin was linear with peak area ranging from 0.02–1.00μg/mL(r=0.9996,n=6)and that of cinnamaldehyde also demonstrated a good linear relationship with peak area in the range of 1.05–52.50μg/mL(r=0.9997,n=6).The average recovery rate of coumarin and cinnamaldehyde was 99.42%and 100.11%,respectively.The investigation of hypoglycemic effect revealed that CCAE could improve weight loss,lower liver and pancreas indices,improve organ damage caused by diabetes,and lower fasting blood glucose,glycosylated serum protein(GSP)and total cholesterol(TC)levels.The results showed that CCAE can reduce fasting blood glucose and blood lipid levels in diabetic mice. | Xuting Hao Ziheng Jin Ruiyu Gao Shiming Li Changqin Li Lijun Liu Jinmei Wang | 2024 | Journal of Future Foods2024，4，2： | 0 |
| 15 | Straw return increases crop production by improving soil organic carbon sequestration and soil aggregation in a long-term wheat-cotton cropping system显示文摘Straw return is a promising strategy for managing soil organic carbon(SOC)and improving yield stability.However,the optimal straw return strategy for sustainable crop production in the wheat(Triticum aestivum L.)-cotton(Gossypium hirsutum L.)cropping system remains uncertain.The objective of this study was to quantify the long-term(10 years)impact of carbon(C)input on SOC sequestration,soil aggregation and crop yields in a wheat-cotton cropping system in the Yangtze River Valley,China.Five treatments were arranged with a single-factor randomized design as follows:no straw return(Control),return of wheat straw only(Wt),return of cotton straw only(Ct),return of 50%wheat and 50%cotton straw(Wh-Ch)and return of 100%wheat and 100%cotton straw(Wt-Ct).In comparison to the Control,the SOC content increased by 8.4 to 20.2%under straw return.A significant linear positive correlation between SOC sequestration and C input(1.42-7.19 Mg ha^(−1)yr^(−1))(P<0.05)was detected.The percentages of aggregates of sizes>2 and 1-2 mm at the 0-20 cm soil depth were also significantly elevated under straw return,with the greatest increase of the aggregate stability in the Wt-Ct treatment(28.1%).The average wheat yields increased by 12.4-36.0%and cotton yields increased by 29.4-73.7%,and significantly linear positive correlations were also detected between C input and the yields of wheat and cotton.The average sustainable yield index(SYI)reached a maximum value of 0.69 when the C input was 7.08 Mg ha^(−1)yr^(−1),which was close to the maximum value(SYI of 0.69,C input of 7.19 Mg ha^(−1)yr^(-1))in the Wt-Ct treatment.Overall,the return of both wheat and cotton straw was the best strategy for improving SOC sequestration,soil aggregation,yields and their sustainability in the wheat-cotton rotation system. | Changqin Yang Xiaojing Wang Jianan Li Guowei Zhang Hongmei Shu Wei Hu Huanyong Han Ruixian Liu Zichun Guo | 2024 | Journal of Integrative Agriculture2024，23，2： | 0 |
| 16 | Transactional Dependency for Failure Recovery in Web Services Composition System显示文摘 | MEI Xiaoyong LI Shixian HUANG Changqin ZHENG Xiaolin | 2012 | Chinese Journal of Electronics2012，21，2： | 0 |
| 17 | Chemical constituents and coagulation effects of the flowers of Rosa chinensis Jacq.显示文摘In this paper,the flowers of Rosa chinensis Jacq.were investigated and 14 compounds were isolated and identified,namely kaempferol(1),quercetin(2),isoquercitrin(3),afzelin(4),quercitrin(5),phenylethyl glucopyranoside(6),avicularin(7),juglanin(8),nicotiflorin(9),phenylethyl-6′-O-galloyl-β-D-glucopyranoside(10),tiliroside(11),methyl gallate(12),8-O-methylherbacetin-3-O-β-D-sophoroside(13),gallic acid(14).Among these compounds,compounds 7,9,12 and 13 were isolated from R.chinensis for the first time.These compounds and extracts of R.chinensis.were studied for coagulation activity in vitro.The results showed that tiliroside(11)had good effect on promoting blood coagulation,and the effect of tiliroside was better than that of Yunnanbaiyao.Juglanin(8)and nicotiflorin(9)could significantly shorten thrombin time(TT)and significantly elevated fibrinogen(FIB),which proved that juglanin and nicotiflorin had good procoagulant effect. | Peiqing Wang Miyun Hu Li Wang Jiaojiao Qu Yuhang Liu Changqin Li Zhenhua Liu Changyang Ma Wenyi Kang | 2023 | Journal of Future Foods2023，3，2： | 0 |
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