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1篇 您的检索式:作者名="Ch. Swamalatha"
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1Note Microwave synthesis and pharmacological activity of Mannich base cyclohexanone derivatives显示文摘We have synthesized mannich base cyclohexanone using microwave irradiation method,and studied their pharma-cological activity.Based on analytical and spectral(IR,NMR and Mass) data,a number of mono as well as double mannich base cyclohexanones have been synthesized from primary and secondary amines and formaldehyde,and then purified and characterized. The required 3-aryl-2,4-diacetyl-5-hydroxy-5-methylcyclohexanone was prepared from appropriate aldehyde and acetylacetone. The synthesized compounds were screened for analgesic activity via standard approaches,and they have shown positive analgesic activity.Ch. Rajveer B. Stephenrathinaraj Naveen Kumar Bimal S. Sudharshini Ch. Swamalatha Prasanta Kumar Choudhury 2010Journal of Chinese Pharmaceutical Sciences2010,19,4:1
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