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| 1 | Nuclear Factor-κB:Activation and Regulation during Toll-Like Receptor Signaling显示文摘Toll-like receptors (TLRs) recognize distinct microbial components to initiate the innate and adaptive immune responses. TLR activation culminates in the expression of appropriate pro-inflammatory and immunomodulatory factors to meet pathogenic challenges. The transcription factor NF-κB is the master regulator of all TLR-induced responses and its activation is the pivotal event in TLR-mediated activation of the innate immune response. Many of the key molecular events required for TLR-induced NF-κB activation have been elucidated. However, much remain to be learned about the ability of TLRs to generate pathogen-specific responses using a limited number of transcription factors. This review will focus on our current understanding of NF-κB activation by TLRs and potential mechanisms for achieving a signal-specific response through NF-κB. | Ruaidhrí J. Carmody | 2007 | Cellular & Molecular Immunology2007，4，1： | 63 |
| 2 | Transcriptional Control of SET DOMAIN GROUP 8 and CAROTENOID ISOMERASE during Arabidopsis Development显示文摘类胡萝卜素是为光合作用, photoprotection 和象骆驼毛的织物和 strigolactones 那样的导出类胡萝卜素的荷尔蒙的生产要求的颜料。类胡萝卜素 biosynthetic 小径在 lycopene 以后区分生产 epsilon 类胡萝卜素和贝它类胡萝卜素,这个分支为决定类胡萝卜素作文是批评的。这里,我们显示出分支点怎么能被修改染色质的 histone methyltransferase 调整,集合领域组 8 (SDG8 ) 指向类胡萝卜素 isomerase (CRTISO ) 。SDG8 被要求在幼苗开发期间维持 CRTISO 的容许的表示,在叶子,射击顶,和一些花的机关。CRTISO 和 SDG8 倡导者显示出记者基因活动的重叠织物特定的模式。有趣地, CRTISO 与花椰菜马赛克病毒 35S 倡导者(CaMV35s ) 和 LCY 倡导者相比以在不同的线之间的更大的可变性显示出不正常的记者基因表示,潜在地,由于 chromosomal,位置完成。CRTISO 倡导者的规定部分地依赖于 SDG8 的存在或缺席。SDG8 (类胡萝卜素和叶绿体规定(ccr1 )) 和 CRTISO (ccr2 ) 的大美人导致改变的类胡萝卜素作文和这能用 CaMV35s 或 CRTISO 倡导者在 ccr2 被恢复。相反,在 ccr1 背景用 CaMV35S 或 CRTISO 倡导者由 CRTISO overexpression 改变 GUS 表示和类胡萝卜素互补的度证明 CRTISO 倡导者和开的读物装裱为 CRTISO 的调停 SDG8 的表示是必要的。 | Christopher I. Cazzonelli Andrea C. Roberts Melanie E. Carmody Barry J. Pogson | 2010 | Molecular Plant2010，3，1： | 8 |
| 3 | TIPE2, a Negative Regulator of Innate and Adaptive Immunity that Maintains Immune Homeostasis显示文摘 | Honghong Sun Shunyou Gong Ruaidhri J. Carmody Anja Hilliard Li Li Jing Sun Li Kong Lingyun Xu Brendan Hilliard Shimin Hu Hao Shen Xiaolu Yang Youhai H. Chen | 2008 | Cell2008，，： | 2 |
| 4 | Using on-site liver 3-D reconstruction and volumetric calculations in split liver transplantation显示文摘BACKGROUND: Split liver transplantation increases the number of grafts available for transplantation. Pre-recovery assessment of liver graft volume is essential for selecting suitable recipients. The purpose of this study was to determine the ability and feasibility of constructing a 3-D model to aid in surgical planning and to predict graft weight prior to an in situ division of the donor liver. METHODS: Over 11 months, 3-D volumetric reconstruction of 4 deceased donors was performed using Pathfinder Scout~? liver volumetric software. Demographic, laboratory, operative, perioperative and survival data for these patients along with donor demographic data were collected prospectively and analyzed retrospectively.RESULTS: The average predicted weight of the grafts from the adult donors obtained from an in situ split procedure were 1130 g(930-1458 g) for the extended right lobe donors and 312 g(222-396 g) for left lateral segment grafts. Actual adult graft weight was 92% of the predicted weight for both the extended right grafts and the left lateral segment grafts. The predicted and actual graft weights for the pediatric donors were 176 g and 210 g for the left lateral segment grafts and 308 g and 280 g for the extended right lobe grafts, respectively. All grafts were transplanted except for the right lobe from the pediatric donors due to the small graft weight.CONCLUSIONS: On-site volumetric assessment of donors provides useful information for the planning of an in situ split and for selection of recipients. This information may expand the donor pool to recipients previously felt to be unsuitable due to donor and/or recipient weight. | Trevor W Reichman Brittany Fiorello Ian Carmody Humberto Bohorquez Ari Cohen John Seal David Bruce George E Loss | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，6： | 2 |
| 5 | Reactive oxygen species as mediators of photoreceptor apoptosis in vitro显示文摘 | Carmody R J McGowan A J Cotter TG | 1999 | Exp Cell Res1999，248，2： | 1 |
| 6 | Predictors of survival after liver transplantation for hepatocellular carcinoma associated with hepatitis C显示文摘 | Shimoda M Ghobrial R Carmody I | 2004 | Liver Transpl2004，10，2： | 1 |
| 7 | Reactive oxygen species as mediators ofphotoreceptor apoptosis in vitro显示文摘 | Carmody RJ McGowan AJ Cotter TG | 1999 | Exp Cell Res1999，248，52： | 1 |
| 8 | Laparoscopic mesh hiatoplasty for paraesophageal hernias and fundoplieations: a critical analysis of the available literature显示文摘 | Johnson JM Carbonell AM Carmody B J | 2006 | Surg Endose2006，20，3： | 1 |
| 9 | Biosynthesis of amphoteri- cin derivatives lacking exocyclic carboxyl groups显示文摘 | Carmody M Murphy B Byrne B | 2005 | Journal of Bio- logical Chemistry2005，280，34： | 1 |
| 10 | Neutrophils as early immunologic effectors in hemorrhage-or endotoxemia-induced acute lung injury显示文摘 | Carmody A Shenkar R | 2000 | Am J Physiol Lung Cell Mol Physiol2000，279，6： | 1 |
| 11 | Cutting edge: HMG - 1 as a mediator of acute lung inflammation显示文摘 | Abraham E Arcaroli J Carmody A | 2000 | J Immunol2000，165，6： | 1 |
| 12 | Early Predictors of 15-Year End-Stage Renal Disease in Hypertensive Patients显示文摘 | Jr Perry J. Philip Miller Jane Rossiter Fornoff Jack D. Baty Mohinder P. Sambhi Gale Rutan David W. Moskowitz Sharon E. Carmody | 1995 | Hypertension1995，，4： | 1 |
| 13 | Symptom burden, quality of life,advance care planning and the potential value of palli- ative care in severely ill haemodialysis patients显示文摘 | Weisbord S D Carmody S S Bruns F J | 2003 | Nephrol Dial Transpl2003，18，13： | 1 |
| 14 | Paraquat poisoning;a review of nineteen cases显示文摘 | Malone J D Carmody M Keogh B | 1971 | J Ir Med Assoc1971，64，405： | 1 |
| 15 | Character istics of Dispositional Mindfulness in Patients with Severe Cardiac Disease显示文摘 | Salmoirago-- Blotcher E Crawford S Carmody J | 2011 | J Evid Based Complementary Altern Med2011，16，3： | 1 |
| 16 | Cutting edge:HMG - 1 as a mediator of acute lung inflammation显示文摘 | Abraham E Arcaroli J Carmody A | 2000 | J Immunol2000，165，6： | 1 |
| 17 | Impact of enhanced Staphylococcus DNA extraction on microbial community measures in cystic fibrosis sputum显示文摘 | Zhao J Carmody LA Kalikin LM | 2012 | PLoS One2012，7，33： | 1 |
| 18 | Perioperative needs of families;Results of a survey显示文摘 | Carmody C Hickey P Bookbinder M | 1991 | Aorn J1991，54，3： | 1 |
| 19 | Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins 显示文摘 | Vuong C Durr M Carmody AB | 2004 | Cell Microbiol2004，6，8： | 1 |
| 20 | TIPE2 ,a negative regulator of innate and adaptive immunity that maintain immune homeostasis显示文摘 | Sun HH Gong SY Carmody RJ | 2008 | Cell2008，133，3： | 1 |
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