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| 1 | 如何设计高质量针刺临床研究:基于证据的专家共识显示文摘本针刺随机对照试验(Randomised controlled trials, RCT)专家共识是基于目前针刺试验面临的最普遍、最关键问题,由临床医生、研究人员、从事针灸和外科的临床试验专家、统计专家、临床流行病学和方法学专家以及患者组成的国际临床研究小组联合制订。该共识将有助于临床试验资助者、注册者以及期刊编辑等评估针刺RCT方案及研究结果的相关性、重要性和质量。 | 张誉清 焦睿珉 Claudia M Witt 劳力行 刘建平 Lehana Thabane Karen J Sherman Mike Cummings Dawn P Richards Eun-Kyung Anna Kim Tae-Hun Kim Myeong Soo Lee Michael E Wechsler Benno Brinkhaus Jun J Mao Caroline A Smith 岗卫娟 刘保延 刘志顺 刘岩 郑晖 吴佳霓 AloBSO Carrasco-Labra Mohit Bhandari Philip J Devereaux 景向红 Gordon Guyatt | 2022 | 英国医学杂志中文版2022，25，6： | 7 |
| 2 | Current and novel approaches in the pharmacological treatment of hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is one of the most lethal malignant tumours worldwide.The mortality-to-incidence ratio is up to 91.6%in many countries,representing the third leading cause of cancer-related deaths.Systemic drugs,including the multikinase inhibitors sorafenib and lenvatinib,are first-line drugs used in HCC treatment.Unfortunately,these therapies are ineffective in most cases due to late diagnosis and the development of tumour resistance.Thus,novel pharmacological alternatives are urgently needed.For instance,immune checkpoint inhibitors have provided new approaches targeting cells of the immune system.Furthermore,monoclonal antibodies against programmed cell death-1 have shown benefits in HCC patients.In addition,drug combinations,including first-line treatment and immunotherapy,as well as drug repurposing,are promising novel therapeutic alternatives.Here,we review the current and novel pharmacological approaches to fight HCC.Preclinical studies,as well as approved and ongoing clinical trials for liver cancer treatment,are discussed.The pharmacological opportunities analysed here should lead to significant improvement in HCC therapy. | Fernanda Villarruel-Melquiades María Eugenia Mendoza-Garrido Claudia M García-Cuellar Yesennia Sánchez-Pérez Julio Isael Pérez-Carreón Javier Camacho | 2023 | World Journal of Gastroenterology2023，29，17： | 2 |
| 3 | Urinary neutrophil gelatinase-associated lipocalin as biomarker in the differential diagnosis of impairment of kidney function in cirrhosis显示文摘 | Claudia Fagundes Marie-No?lle Pépin Mónica Guevara Rogelio Barreto Gregori Casals Elsa Solà Gustavo Pereira Ezequiel Rodríguez Elisabet Garcia Verónica Prado Esteban Poch Wladimiro Jiménez Javier Fernández Vicente Arroyo Pere Ginès | 2012 | Journal of Hepatology2012，，2： | 2 |
| 4 | A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome显示文摘 | Claudia M Tonino E Rosa D P | 2002 | Diabetes2002，51，7： | 1 |
| 5 | Structural aspects of the Mucor bacilliformis proteinase, a new member of the aspar- tyl-proteinase family显示文摘 | CLAUDIA M MARIA L P C1KISTINA M | 2006 | Journal of Biotechnology2006，123，： | 1 |
| 6 | Id-1,ITF-2,and Id-2 Comprise a Network of Helix-Loop-Helix Proteins That Regulate Mammary Epithelial Cell Proliferation,Differentiation,and Apoptosis显示文摘 | Simona P Claudia QL Kenji M | 2001 | J Biol Chem2001，276，39： | 1 |
| 7 | Patagonicoside:a novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus显示文摘 | Ana P M Claudia M Alicia M S | 2001 | JTetrahedron2001，，57： | 1 |
| 8 | Fast liquid chromatography/tandem mass spectrometry ( highly selective selected reaction monitoring) for the determination of toltrazuril and its metabolites in food显示文摘 | Anna M V Encamacion M Martins Claudia P B | 2010 | Analytical and Bioanalytical Chemistry2010，397，7： | 1 |
| 9 | Heat recovery from Diesel engines:A thermodynamic com- parison between Kalina and ORC cycle 显示文摘 | BOMBARDA P COSTANTE M I CLAUDIA P | 2010 | Applied Thermal Engineering2010，33，23： | 1 |
| 10 | Solitary gastric recur- rence from ovarian carcinoma:A case report and literature review 显示文摘 | Milena P Natalina M Claudia M | 2006 | Surg Oncol2006，15，： | 1 |
| 11 | Accumulation and partitioning of heavy metals in mangroves: A synthesis of field-based studies 显示文摘 | Geoff R M Claudia E K Simon P B | 2007 | Chemosphere2007，69，9： | 1 |
| 12 | Decolorization of reactive dyes by immobilized laccase显示文摘 | PATRICIO P Z CLAUDIA M P ELAINE R L | 2003 | Applied Catalysis B:Environmemal2003，42，2： | 1 |
| 13 | Heart-type fatty acid -binding protein permits early risk stratification of pulmonary embolism 显示文摘 | Miriam P Claudia D M areike L | 2007 | EurHeart J2007，28，： | 1 |
| 14 | Intermittent acti- vation of bradykinin B2 receptor and mitochondrial KATP channels trigger cardiac postconditioning through redox sig- naling显示文摘 | Claudia P Daniele M Raffaelta R | 2007 | Cardiovasc Res2007，75，1： | 1 |
| 15 | Somatic embryogenesis and plant regeneration through cellsuspensions in Musa acumninata 显示文摘 | CLAUDIA G M CECILE P JEAN V E | 1993 | In Vitro Cell Del Biol1993，29，： | 1 |
| 16 | Cardioprotection: A radical view Free radicals in pre and postconditioning 显示文摘 | Claudia P Daniele M Raffaella R | 2009 | Biochimiea et Biophysica Acta2009，1787，： | 1 |
| 17 | A dendritic cell vaccine against invasive aspergillosis in allogeneic hemotopoietic transplantation显示文摘 | Silvia B Katia P Claudia M | 2003 | Blood2003，102，10： | 1 |
| 18 | Plant grow promoting properties of a strain of Enterobacter ludwigii isolated firom Lolium pernne rhizosphere显示文摘 | Mauricio S Claudia M R Martin A P | 2008 | Soil Biology and Biochemistry2008，41，2009： | 1 |
| 19 | A haplotype at theadiponectin locus is associated with obesity and other features of theinsulin resistance syndrome显示文摘 | Claudia M Tonino E Rosa D P | 2002 | Diabetes2002，51，： | 1 |
| 20 | To split or not to split: That is the question 显示文摘 | ARCHETrI CLAUDIA MARTIN W P SAVEI_SBERGH M | 2008 | Transportation Research-Part E2008，，44： | 1 |
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