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    题名 作者 年代 出处 被引量
1Variable epitope library-based vaccines:shooting moving targets显示文摘CESAR P R CLAUDIA C N RAFAEL S 2009Molecular Immunology2009,47,2:1
2Dietary advanced glycation end products and aging显示文摘Claudia L C Karen C N 2010Nutrients2010,2,:1
3Forwarding strategies innamed data wireless ad hoc networks: design and evaluation显示文摘MARICA A CLAUDIA C ANTONELLA N 2015Jour-nal of Network and Computer Applications2015,50,:1
4Chemical composition of flavonoids and styrylpyrones and the genetic variability of isozymes in natural populations of Cryptocarya mandioccana Meisner (Lauraceae)显示文摘PEDRO L R D CLAUDIA J N MERCELO C A 2007Biochem Syst Ecol2007,35,4:1
5Nitrogen distribution, remobilization and re - cycling in young orchard of non - bearing ' Rocha' pear trees 显示文摘Claudia N Corina C Josue C 2008Scientia Horticulturae2008,118,:1
6Active tuberculosis in inflammatory bowel disease patients under treatment from an endemic area in Latin America显示文摘BACKGROUND There has been an increase in cases of inflammatory bowel disease(IBD)in recent years.There is also greater access and availability of immunosuppressive and biological agents,which increase the risk of opportunistic infection despite improving the quality of life and promoting mucosal healing.Tuberculosis(TB)remains a public health problem,and it has a high incidence in several countries.Therefore,knowledge of the risk of developing TB in patients with IBD is important.AIM To evaluate the risk of active TB in patients with IBD under treatment from an endemic area in Latin America.METHODS A standard questionnaire included demographic variables,clinical aspects of IBD disease,history of active TB during treatment,active TB characteristics and evolution,initial screening and results and time from the start of anti-tumor necrosis factor alpha(TNFα)to TB development.RESULTS Azathioprine,anti-TNFα and the combination of these two drugs were associated with a higher risk of active TB incidence.The TNFα blockers increased the relative risk of developing active TB compared to other treatments.All four multivariable models showed that the use of TNFα blockers alone or in combination with azathioprine was an important risk factor for the incidence of active TB.After adjustment for sex,age,type of IBD and latent TB,anti-TNFα with azathioprine increased the relative risk to 17.8 times more than conventional treatment.Late TB,which was diagnosed 3 mo after the start of anti-TNFα,was the most frequent.CONCLUSION Treatment with anti-TNFα increased the risk of active TB in IBD patients from an endemic area in Latin America.This risk was increased when anti-TNFα was combined with azathioprine.The time from the beginning of the treatment to the active TB diagnosis suggests a new TB infection.Flora Maria Lorenzo Fortes Ney Boa Sorte Victor D Mariano Laila D Andrade Fernanda A Oliveira Monique CA Santos Claudia Ivanilda N dos Santos Catharina A Passos Mila P Pacheco Valdiana C Surlo Neogelia P de Almeida Jaciane AM Fontes Andrea M Pimentel Raquel Rocha Genoile Oliveira Santana 2020World Journal of Gastroenterology2020,26,44:1
7Boron removal by the duckweed Lerrma gibba: A potential method for the remediation of boron-polluted waters显示文摘CLAUDIA M MAR~N D C ORON G 2007Water Res2007,41,20:1
8Frequencies of GSTM1, GSTT1, and GSTP 1 polymorphisms in a Brazilian population显示文摘Ana Rossinil Davy C M Rapozol Lidia M F Amorim2 Jacyara M B Macedo1 Raquel Medina1 Jose F N Neto3 Claudia V M Gallol and Luis F R Pintol 2002Genetics and Molecular Research2002,1,3:1
9Effect of Applied Potential on Photocatalytic Phenol Degradation Using Nanocrystalline TiO2 Electrodes 显示文摘Haroldo G O Daiane C N Claudia L 2010Applied Catalysis B: Environmental2010,93,3:1
10Triterpenes and other constituents of Nassauvia axillaris 显示文摘Claudia K Cesar A N C Claire L G 2005Biochem Systematics Ecolo2005,33,7:1
11Variable epitope library-based vaccines:Shooting moving targets显示文摘Cesar P R Claudia C N Rafael S 2009Mol Immunol2009,47,2:1
12Capture of fine and ultra_fine particles in a wet electrostatic scrubber 显示文摘FRANCESCO D N CLAUDIA C LUCA D A 2015Journal of Environmental Chemical Engineering2015,,3:1
13Recovery of protein from chrome shavings and application as a food supplement for tilapia oreochromis niloticus 显示文摘Eurica M N Claudia C M 2000JALCA12000,95,:1
14Estimation of soil moisture patterns in mountain grasslands by means of SAR RADARSATS images and hydrologcial modeling 显示文摘GIACOMO B STEFANO C CLAUDIA N 2014Journal of Hydrology2014,516,:1
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