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| 1 | 亚太地区慢性乙型肝炎治疗共识(2012最新版)显示文摘自2008年至今,有大量关于慢性HBV感染的自然史和治疗的最新数据不断涌现。其中包括慢性HBV感染的无症状感染者,以社区为基础的队列研究,HBV基因型的作用,非药物诱导的自然HBV变异型毒株,无创性肝纤维化评估方法的应用,HBsAg定量在临床中的应用,更有效的新治疗药物和新治疗方案等等。来自亚太地区的专家审查和评估了相关数据,并共同商讨了近年来报道的最有意义的发现,基于此,对2008年版的亚太地区慢性乙型肝炎治疗共识进行修订,同时对2008年版治疗指南定义的关键词组进行了修订。修订后的指南包括以下几方面内容:一般治疗,肝纤维化评价适应证,何时开始治疗或停药,初始抗病毒治疗药物的选择,如何监测治疗中和治疗后的患者。关于特殊人群的治疗建议中包括了对妊娠妇女,已发生耐药,合并其他病毒感染,肝功能失代偿,接受免疫抑制治疗、化疗,肝移植或肝细胞癌患者的具体治疗建议。 | 廖运范 Jia-HorngKao Teerha Piratvisuth Henry Lik Yuen Chan Rong-Nan Chien Chun-Jen Liu Ed Gane Stephen Locarnini Seng-Gee Lim Kwang-Hyub Han Deepak Amarapurkar Graham Cooksley Wasim Jafri Rosmawati Mohamed Wan-Long Chuang Laurentius A.Lesmana Jose D.Sollano Dong-Jin Suh Masao Omata 刘颖 徐莹 李芸 黄祖雄 樊蓉 李小溪 吕国涛 周彬 孙剑 侯金林 | 2012 | 临床肝胆病杂志2012，28，8： | 182 |
| 2 | Clinical correlation of gallstone disease in a Chinese population in Taiwan:Experience at Cheng Hsin General Hospital显示文摘瞄准:在与它有关的台湾和联系条件的因素探索胆石疾病(GSD ) 的流行。方法:我们自愿地学习了 2386 个健康成年人(1235 男性和 1151 女性) 的一个总数为在 2002 年 1 月和 2002 年 12 月之间的付的物理检查承认了到 Cheng Hsin 医院将军。血样品和超声 sonography 结果是镇定的。结果:在这张学习人口之中的 GSD 的全面流行是 5.3% ,包括 1.7%(n=40 ) 有一块单个石头, 2.3%(n=55 ) 有多重石头,并且 1.3%(n=31 ) 有胆囊炎。流行与增加年龄(P<0.0001 ) 揭示了统计上重要的增加。女性们比展出了多重石头的更大的流行做了男性(3.0% 对 1.7% , P=0.04 ) 。用多重逻辑回归分析,下列看起来是显著地与 GSD 的流行有关:老年(40-49 年对 <
40 年, OR=1.63 [95% CI:0.76-3.48 ] , 50-59 年对 <
40 年, OR=4.93 [95% CI:2.43-9.99 ] , 60-69 年对 <
40 年, OR=6.82 [95% CI:3.19-14.60 ] , >
或 = 70 年对 <
40 年, OR=10.65 [95% CI:4.78-23.73 ]) ,更高的 BMI (>
或 = 27 kg/m2 对 <
24 kg/m2,调整 OR=1.74 [95% CI:1.04-2.88 ]) ,并且更高的 FPG (>
或 = 126 mg/dL 对 <
110 mg/dL, OR=1.71, 95%CI:1.01-2.96 ) 。结论:老年(>
或 = 50 年) ,肥胖(BMI >
或 = 27 kg/m2 ) ,并且类型 2 糖尿病(FPG >
或 = 126 mg/dL ) 与 GSD 的流行被联系。 | Chi-Ming Liu Tao-Hsin Tung Pesus Chou Victor Tze-Kai Chen Chung-Te Hsu Wu-Shyong Chien Yeu-Tyng Lin Hsu-Feng Lu Hui-Chuan Shih Jorn-Hon Liu | 2006 | World Journal of Gastroenterology2006，12，8： | 11 |
| 3 | Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update显示文摘 | Yun-Fan Liaw Jia-Horng Kao Teerha Piratvisuth Henry Chan Rong-Nan Chien Chun-Jen Liu Ed Gane Stephen Locarnini Seng-Gee Lim Kwang-Hyub Han Deepak Amarapurkar Graham Cooksley Wasim Jafri Rosmawati Mohamed Jin-Lin Hou Wan-Long Chuang Laurentius Lesmana Jose | 2012 | Hepatology International2012，，3： | 6 |
| 4 | Sedation-associated hiccups in adults undergoing gastrointestinal endoscopy and colonoscopy显示文摘AIM:To investigate whether the incidence of hiccups in patients undergoing esophagogastroduodenoscopy (EGD) or same-day bidirectional endoscopy (EGD and colonoscopy;BDE) with sedation is different from those without sedation in terms of quantity,duration and typical onset time.METHODS:Consecutive patients scheduled for elective EGD or same-day BDE at the gastrointestinal endoscopy unit or the health examination center were allocated to two groups:EGD without sedation (Group A) and BDE with sedation (Group B).The use of sedation was based on the patients' request.Anesthesiologists participated in this study by administrating sedative drugs as usual.A single experienced gastroenterologist performed both the EGD and the colonoscopic examinations for all the patients.The incidence,duration and onset time of hiccups were measured in both groups.In addition,the association between clinical variables and hiccups were analyzed.RESULTS:A total of 435 patients were enrolled in the study.The incidences of hiccups in the patients with and without sedation were significantly different (20.5% and 5.1%,respectively).The use of sedation for patients undergoing endoscopy was still significantly associated with an increased risk of hiccups (adjusted odds ratio:8.79,P < 0.001) after adjustment.The incidence of hiccups in males under sedation was high (67.4%).The sedated patients who received 2 mg midazolam developed hiccups more frequently compared to those receiving 1 mg midazolam (P = 0.0028).The patients with the diagnosis of gastroesophageal reflux disease (GERD) were prone to develop hiccups (P = 0.018).CONCLUSION:Male patients undergoing EGD or BDE with sedation are significantly more likely to suffer from hiccups compared to those without sedation.Midazolam was significantly associated with an increased risk of hiccups.Furthermore,patients with GERD are prone to develop hiccups. | Chien Cheng Liu Cheng Yuan Lu Chih Fang Changchien Ping Hsin Liu Daw Shyong Perng | 2012 | World Journal of Gastroenterology2012，18，27： | 4 |
| 5 | Phylotranscriptomic insights into Asteraceae diversity,polyploidy,and morphological innovation显示文摘Biodiversity is not evenly distributed among relatedgroups,raising questions about the factors con-tributing to such disparities.The sunflower family(Asteraceae,>26,000 species)is among the largestand most diverse plant families,but its species di-versity is concentrated in a few subfamilies,pro-viding an opportunity to study the factors affectingbiodiversity.Phylotranscriptomic analyses here of244 transcriptomes and genomes produced a phy-logeny with strong support for the monophyly ofAsteraceae and the monophyly of most subfamiliesand tribes.This phylogeny provides a reference fordetecting changes in diversification rates and pos-sible factors affecting Asteraceae diversity,whichinclude global climate shifts,whole‐genome dupli-cations(WGDs),and morphological evolution.Theorigin of Asteraceae was estimated at~83 Mya,with most subfamilies having diverged before theCretaceous–Paleocene boundary.Phylotran-scriptomic analyses supported the existence of 41WGDs in Asteraceae.Changes to herbaceousnessand capitulescence with multipleflower‐like capitula,often with distinctflorets and scaly pappus/re-ceptacular bracts,are associated with multiple up-shifts in diversification rate.WGDs might have con-tributed to the survival of early Asteraceae byproviding new genetic materials to support mor-phological transitions.The resulting competitive ad-vantage for adapting to different niches would haveincreased biodiversity in Asteraceae. | Caifei Zhang Chien‐Hsun Huang Mian Liu YiHu Jose L.Panero Federico Luebert Tiangang Gao Hong Ma | 2021 | Journal of Integrative Plant Biology2021，63，7： | 4 |
| 6 | Metabolic Factors and Risk of Hepatocellular Carcinoma by Chronic Hepatitis B/C Infection: A Follow-up Study in Taiwan显示文摘 | Chi–Ling Chen Hwai–I. Yang Wei–Shiung Yang Chun–Jen Liu Pei–Jer Chen San–Lin You Li–Yu Wang Chien–An Sun Sheng–Nan Lu Ding–Shin Chen Chien–Jen Chen | 2008 | Gastroenterology2008，，1： | 3 |
| 7 | Prediction models of long‐term Cirrhosis and hepatocellular carcinoma risk in chronic hepatitis B patients: Risk scores integrating host and virus profiles显示文摘 | Mei‐Hsuan Lee Hwai‐I. Yang Jessica Liu Richard Batrla‐Utermann Chin‐Lan Jen Uchenna H. Iloeje Sheng‐Nan Lu San‐Lin You Li‐Yu Wang Chien‐Jen Chen | 2013 | Hepatology2013，，2： | 3 |
| 8 | MicroRNA-18a Prevents Estrogen Receptor-α Expression, Promoting Proliferation of Hepatocellular Carcinoma Cells显示文摘 | Wan–Hsin Liu Shiou–Hwei Yeh Cho–Chun Lu Sung–Liang Yu Hsuan–Yu Chen Chien–Yu Lin Ding–Shinn Chen Pei–Jer Chen | 2009 | Gastroenterology2009，，2： | 2 |
| 9 | Erratum to: Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update显示文摘 | Yun-Fan Liaw Jia-Horng Kao Teerha Piratvisuth Henry Lik Yuen Chan Rong-Nan Chien Chun-Jen Liu Ed Gane Stephen Locarnini Seng-Gee Lim Kwang-Hyub Han Deepak Amarapurkar Graham Cooksley Wasim Jafri Rosmawati Mohamed Jin-Lin Hou Wan-Long Chuang Laurentius A. | 2012 | Hepatology International2012，，4： | 2 |
| 10 | Evaluation of floating car technologies for travel time estimation显示文摘Travel times have been traditionally estimated from data collected by roadway sensors.Recently,new technologies,such as cell phone tracking,license plate matching,automatic vehicle identifications and video detection,are employed for this purpose.In this study,the data collected by TRANSMIT readers,Bluetooth sensors,and INRIX are assessed by comparing each to the 'ground truth' travel times collected by probe vehicles carrying GPS-based navigation devices.Travel times of probe vehicles traveling on the study segment of I-287 in New Jersey were collected in 2009.Statistical measures,such as standard deviation,average absolute speed error,and speed error bias,were used to make an in-depth analysis.The accuracy of each travel time estimation method is analyzed.The data collected by Bluetooth sensors and the TRANSMIT readers seem more consistent with the ground true data,and slightly outperform the data reported by INRIX.This study established a procedure for analyzing the accuracy of floating car data (FCD) collected by different technologies. | Xiaobo LIU Steven CHIEN Kitae KIM | 2012 | Journal of Modern Transportation2012，20，1： | 2 |
| 11 | Blood neutrophil‐to‐lymphocyte ratio correlates with tumor size in patients with differentiated thyroid cancer显示文摘 | Chien‐Liang Liu Jie‐Jen Lee Tsang‐Pai Liu Yuan‐Ching Chang Yi‐Chiung Hsu Shih‐Ping Cheng | 2012 | J. Surg. Oncol2012，，5： | 2 |
| 12 | Mineral scaling mitigation in cooling systems using tertiary-treated municipal wastewater显示文摘 | LIU W CHIEN S H DZOMBAK D A | 2012 | Water Research2012，46，14： | 1 |
| 13 | Variable mold temperature to improve surface quality of microcellular injection molded parts using induction heating technology 显示文摘 | CHEN S C LIU Y W CHIEN R D LI H M | 2008 | Advances in Polymer Technology2008，27，4： | 1 |
| 14 | Effect of Previous Live Birth and Prior Route of Delivery on the Outcome of Early Medical Abortion显示文摘 | Chien LW Liu WM Tzeng CR | 2009 | Obstet Gynecol2009，113，3： | 1 |
| 15 | The As- sociation between Auditor Quality and Human Capital显示文摘 | Cheng Yu Shu Liu Yi Pei Chien Chu Yang | 2009 | Man- agerial Auditing Journal2009，6，： | 1 |
| 16 | Characterization of thyroid nodules using the proposed thyroid imaging reporting and data system (TI‐RADS)显示文摘 | Shih‐Ping Cheng Jie‐Jen Lee Jiun‐Lu Lin Shih‐Ming Chuang Ming‐Nan Chien Chien‐Liang Liu | 2012 | Head Neck2012，，4： | 1 |
| 17 | Application of bifunctional magnetic adsorbent to adsorb metal cations and anionic dyes in aqueous solution显示文摘 | Ya-Fen Lin Hua-Wei Chen Poh-Sun Chien Chyow-San Chiou Cheng-Chung Liu | 2010 | Journal of Hazardous Materials2010，，2： | 1 |
| 18 | Observation of coherent optical information storage in an atomic medium using halted light pulses显示文摘 | CHIEN Liu DUTTON Z BEHROozI C H | 2001 | Nature2001，409，： | 1 |
| 19 | Mineral scaling mitigation in cooling systems using tertiary-treated municipal wastewater显示文摘 | Liu W Chien S H Dzombak D A | 2012 | Wa- ter Research2012，46，14： | 1 |
| 20 | Urine sediment examination: a comparison of automated urinalysis systems and manual microsco py显示文摘 | Chien TI Kao JT Liu HL | 2007 | Clin Chim Aeta2007，384，12： | 1 |
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