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180篇 您的检索式:作者名="Buttgereit"
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1Human immune cells' behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model显示文摘骨头骨折愈合的起始的煽动性的阶段为愈合的过程的结果代表关键步。然而,开始这个煽动性的阶段的机制和在破裂地点在场的有免疫力的房间的功能糟糕被理解。以便在破裂 hematoma 以内学习早事件,我们建立了一在里面 vitro 破裂 hematoma 模型:我们有教养的 hematomas 在 bioenergetically 控制的条件下面在 vitro 在全部的新潮的关节造形术(THA ) 期间在腿节的截骨术(人工的骨头破裂) 期间形成。这个模型允许我们在跟随破裂的早阶段期间监视有免疫力的房间人口,房间幸存和 cytokine 表示。而且,这个模型使我们能改变 bioenergetical 条件以便模仿在里面 vivo 状况,它被假定被组织缺氧描绘并且限制了营养素的数量。用这个模型,我们发现有免疫力的房间经由 angiogenic 因素, chemoattractants 和支持 inflammatory 分子的表示适应组织缺氧。另外,联合了氧的限制,滋养的供应与 myeloid 的比较提高了淋巴细胞的选择幸存导出的房间(即, neutrophils ) 。笔记,非限制的 bioenergetical 条件没关于 cytokine 表示或有免疫力的房间子集的不同幸存率显示出任何类似的效果。在结论,我们发现 bioenergetical 条件在导致骨折愈合的起始的煽动性的阶段的关键因素之中并且因此是为在早破裂 hematoma 影响有免疫力的房间的幸存和功能的一个关键步骤。Paula Hoff Patrick Maschmeyer Timo Gaber Tabea Schiitze Tobias Raue Katharina Schmidt-Bleek Rene Dziurla Saskia Schellmann Ferenz Leonard Lohanatha Eric Rohner Andrea Ode Gerd-Riidiger Burmester Georg N Duda Carsten Perka Frank Buttgereit 2013Cellular & Molecular Immunology2013,10,2:3
2糖皮质激素在低疾病活动度的类风湿关节炎患者中的应用:一项多中心、双盲、随机对照试验显示文摘类风湿关节炎(RA)是一种以关节滑膜慢性炎症为特征的系统性自身免疫性疾病。相较于传统的改善风湿病情药物,糖皮质激素具有起效快的优点,既往的ACR及EULAR指南中均推荐在RA起始治疗中,可使用小剂量糖皮质激素作为“桥接疗法”。但糖皮质激素的使用可能给RA患者带来骨质疏松、肾上腺轴功能抑制、类固醇糖尿病等副作用。以往研究表明,持续低剂量使用泼尼松的RA患者可获得更好的临床疗效,但目前尚无针对特定的低剂量泼尼松减量治疗方案与持续低剂量泼尼松治疗方案的双盲、随机、安慰剂对照试验的报道。Burmester GR Buttgereit F Bernasconi C 姜钒(编译) 2021中华医学杂志2021,101,28:2
3blethotrexate treatment in large vessel vasculitis and polymyalgia rheumatic显示文摘Spies CM Burmester GR Buttgereit F 2010Clin Exp Rheumatol2010,28,561:1
4Rapid glucocorticoid effects on immune cells显示文摘Frank Buttgereit Alexander Scheffold 2002Steroids2002,,6:1
5Rapid glucocorticoid effects on immune cells显示文摘Buttgereit F Scheffold A 2002Steroids2002,67,6:1
6Low-dose prednisone ehronotherapy for rheumatoid arthritis:a randomised clinieal trial(CAPRA-2)显示文摘BUTTGEREIT F MEHTA D KIRWAN J 2013Ann Rheum Dis2013,72,2:1
7Targeting of natural killer-Like T immunologic effector cells against Leukemia and lymphoma cellsby reverse antibody-dependent cellular cytotoxicity 显示文摘Lefterova P Marten A Buttgereit P 2000J Immu2000,23,3:1
8New insights into the fascinating world of glucocorticoids:the dexamethasone-miR-342-Rictor axis in regulatory T cells显示文摘In a recent issue of Immunity,Kim et al.reported previously unknown effects of glucocorticoids on murine regulatory T(Treg)cells,and this report added another very interesting perspective to the already very diverse body of knowledge about these important hormones and therapeutics compared to the body of knowledge about other clinically used drugs.1 Treg cells are important regulators of the immune response in autoimmune and allergic inflammation.Frank Buttgereit Timo Gaber 2021Cellular & Molecular Immunology2021,18,3:1
9Efficient gene transfer into lymphoma cells using adenoviral vectors combined with lipofection显示文摘BUTTGEREIT P WEINECK S ROPKE G 2000Cancer Gene Ther2000,7,8:1
10Bioenergetics of immune functions:fundamental and therapeutic aspects显示文摘Buttgereit F Burmester GR Brand MD 2000Immunol Today2000,21,4:1
11Non-genomic glucocorticoid effects to provide the basis for new drug developments显示文摘Song I H Buttgereit F 2006Mol Cell Endocrinol2006,246,12:1
12Generation of activated and antigen-specific T cells with cytotoxic activity after co-culture with dendritic cells显示文摘Angela M?rten Tim Greten Carsten Ziske Sabine Renoth Bj?rn Sch?ttker Peter Buttgereit Frank Schakowski Alexander von Rücker Tilman Sauerbruch Ingo G. Schmidt-Wolf 2002Cancer ImmunologyImmunotherapy2002,,1:1
13Standardised nomencla ture for glucocorticoid dosages and glucocorticoid treatment regi mens:current questions and tentative answers in rheumatolo gy显示文摘Buttgereit F da Silva JA Boers M 0,,08:1
14Molecular mechanisms of glucocorticoid-induced osteoporosis显示文摘Patschan D Loddenkemper K Buttgereit F 2001Bone2001,29,6:1
15Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands 显示文摘Lowenberg M Stahn C Hommes DW Buttgereit F 2008Steroids2008,73,910:1
16Energy reg-ulation and neuroendocrine-immune control in chronic inflamma-tory diseases显示文摘STRAUB R H CUTOLO M BUTTGEREIT F 2010J Intern Med2010,267,6:1
17Which dose regimen for glucocorticoid pulse therapy in patients with severe refractory RA显示文摘Buttgereit F Burmester G Bijlsma J W 2005Ann Rheum Dis2005,64,1:1
18Gene therapy of lymphoma 显示文摘Buttgereit P Schmidt-Wolf IG 2002J Hematother Stem Cell Res2002,11,3:1
19A new hypothesis of modular glucocorticoid actions:steroid treatment of rheumatic diseases revisited显示文摘Buttgereit F Wehling M Burmester GR 1998Arthritis Rheum1998,41,5:1
20Targeting of natural killer-like T immunologic effector cells against leukemia and lymphoma cells by reverse antibody-dependent cellular cytotoxicity显示文摘Lefterova P Marten A Buttgereit P 2000J Immunother2000,23,:1
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