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5篇 您的检索式:作者名="Brian Kinsella"
    题名 作者 年代 出处 被引量
1原子力显微镜评价奥氏体不锈钢晶间腐蚀敏感性的研究显示文摘由13Cr可焊马氏体不锈钢(WMSGSS)制造的油气管线由于价格便宜,相对于昂贵的耐腐蚀合金来说是一个很有竞争力的选择。但是实验室试验和现场经历表明,13Cr马氏体不锈钢焊接接头热影响区发生了沿晶应力腐蚀开裂(IGSCC)。对于低等级的马氏体不锈钢来说,沿晶应力腐蚀开裂机理被认为是在晶界的碳化物附近存在贫铬区。对于中等级和高等级马氏体不锈钢来说,只在实验室试验发现有应力腐蚀开裂。它们的应力腐蚀开裂机理还没有明确,虽然最可能的应力腐蚀开裂机理也被认为和低等级马氏体不锈钢的应力腐蚀开裂机理类似。原子力显微镜(AFM)已开始广泛用于材料显微组织和环境敏感断裂的研究中。高等级马氏体不锈钢焊接接头对晶间腐蚀/应力腐蚀开裂敏感性很有希望由原子力显微镜检测到。在原子力显微镜技术应用于这项研究之前,用由304不锈钢准备的不同敏化度的试样来确定它的适用性是十分有益的。本文用原子力显微镜研究了不同敏化程度的304不锈钢的晶间腐蚀敏感性并和SEM和EDS结果进行了对比。黄彦良 Brian Kinsella Thomas Becker 黄偲迪 张杨扬 2008材料开发与应用2008,23,3:5
2Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS.Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight 2010Cellular & Molecular Immunology2010,7,3:3
3Mapping non-uniform corrosion using the wire beam electrode method. I. Multi-phase carbon dioxide corrosion显示文摘Yong-Jun Tan Stuart Bailey Brian Kinsella 2001Corrosion Science2001,,10:2
4全面库存透视带来更多销售显示文摘货架无货是零售企业之大忌。许多零售商充分认识到缺货意味着企业利润的损失。然而,现今零售环境日趋复杂,确保货架有货并非最佳方法,而提高库存透视度才能带来更多销售。Brian Kinsella 2011信息与电脑2011,,8:0
5陈列室现象:是挑战,还是机遇显示文摘简而言之,陈列室现象指的是购物者进入实体店,找到所需产品后,进行拍照或扫描,然后离开门店以更低的价格进行网上购物。Brian Kinsella 2012信息与电脑2012,,10:0
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