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| 1 | Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level显示文摘Mesenchymal stem cells(MSCs)have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions,including the paracrine effect,cell fusion,and mechanical and electrical couplings.Due to heart–muscle complexity,progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC–cardiomyocyte coculture.In conventional coculture systems,however,the in vivo cardiac muscle structure,in which rod-shaped cells are connected end-to-end,is not sustained;instead,irregularly shaped cells spread randomly,resulting in randomly distributed cell junctions.Consequently,contact-mediated cell–cell interactions(e.g.,the electrical triggering signal and the mechanical contraction wave that propagate through MSC–cardiomyocyte junctions)occur randomly.Thus,the data generated on the beneficial effects of MSCs may be irrelevant to in vivo biological processes.In this study,we explored whether cardiomyocyte alignment,the most important phenotype,is relevant to stem cell cardiogenic differentiation.Here,we report(i)the construction of a laser-patterned,biochip-based,stem cell–cardiomyocyte coculture model with controlled cell alignment;and(ii)single-cell-level data on stem cell cardiogenic differentiation under in vivo-like cardiomyocyte alignment conditions. | Zhen Ma Qiuying Liu Huaxiao Yang Raymond B Runyan Carol A Eisenberg Meifeng Xu Thomas K Borg Roger Markwald Yifei Wang Bruce Z Gao | 2013 | Light(Science & Applications)2013，2，1： | 2 |
| 2 | Correlation of VEGF production with IL - 1α and IL - 6 secretion by human pituitary adenoma cells 显示文摘 | BORG S A KERRY K E ROYDS J A | 2005 | European Journal of Endocrinology2005，152，： | 1 |
| 3 | Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with type I diabetes:a three-month study显示文摘 | Johansson BL Borg K Fernqvist-Forbes E | 2000 | Diabetic Med2000，17，3： | 1 |
| 4 | Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitisB using HBsAg and HBV DNA levels 显示文摘 | Rijckborst V Hansen BE Cakaloglu Y Ferenci P Tabak F Akdogan M Simon K Akarca US Flisiak R Verhey E Van Vuuren AJ Boucher CA ter Borg MJ Janssen HL | 2010 | Hepatology2010，52，2： | 1 |
| 5 | Dynamic interactions between myocytes, fibroblasts, and extracellular matrix 显示文摘 | Banerjee I Yekkala K Borg TK | 2006 | Ann N Y Acad Sci2006，1080，： | 1 |
| 6 | Correlation-based visual oclometry for ground vehicles 显示文摘 | NOURANI-VATANI N VINICIUS P BORGES K | 2011 | Journal of Field Robotics2011，28，5： | 1 |
| 7 | Clinical use of ultrasensitive cardiac troponin I assay in intermediate- and high-risk surgery patients 显示文摘 | Borges F K Furtado M V Rossini A P | 2013 | Dis Markers2013，35，6： | 1 |
| 8 | Simulating DCB,ENF and MMB experiments using shell elements and a cohesive zone model显示文摘 | Borg R Nilsson L Simonsson K | | 0，，02： | 1 |
| 9 | An efficient, thermally stable cerium-based silicate phosphor for solid state white lighting显示文摘 | Brgoch J Borg C K H Denanlt K A | 2013 | Inorg Chem2013，52，14： | 1 |
| 10 | Uptake and transport of manganese in primary and secondary olfactory neurones in pike显示文摘 | Tjalve H Mejàre C Borg Neczak K | 1995 | Pharmacol Toxicol1995，77，1： | 1 |
| 11 | IL - 6 is associated with pituitary tumour invasiveness 显示文摘 | SULIMAN M BORG S KERRY K | 2001 | Endocrine Pathology2001，12，： | 1 |
| 12 | Mercury in fish muscle in acidified and limed lakes显示文摘 | P. Andersson H. Borg P. K?rrhage | 1995 | Water Air & Soil Pollution (-)1995，，1： | 1 |
| 13 | Dynamic interactions between myocytes, fibroblasts, and extracellular matrix显示文摘 | Banerjee K Yekkala K Borg TK | 2006 | Ann NY Acad Sci2006，108，： | 1 |
| 14 | Accumulation of waterbome mercury(Ⅱ) in specific areas of fish brain显示文摘 | Rouleau C Borg Neczak K Gottofrey J | 1999 | ES & T1999，333，： | 1 |
| 15 | Muscle fiber atrophy in leg muscles after botulium toxin type A treatment of cervical dystonis显示文摘 | Ansved T Odegren T Borg K | 1997 | Neurology1997，48，： | 1 |
| 16 | Development of emo- tional intelligence in a team-based learning internal medicine clerkship 显示文摘 | Borges N J Kirkham K Deardorff AS | 2012 | Med Teach2012，34，10： | 1 |
| 17 | Life satisfaction among older people with reduced self care capacity; the relationship to social, health and financial aspects显示文摘 | Borg C Hallberg I R Blomqvist K | 2006 | Journal of Clinical Nursing2006，15，5： | 1 |
| 18 | OMT-G: An Object- oriented Data Model for Geographic Application显示文摘 | Borges K Clodoveu A Alberto L | 2001 | Geoinformatica2001，5，3： | 1 |
| 19 | Light-activated ion channels for remote control of neuronal firing显示文摘 | Banghart M Borges K Isacoff E | 2004 | Nat Neurosci2004，7，12： | 1 |
| 20 | Down-regulation of the aberrant expression of the inflammation mediator high mobility group box chromosomal protein 1 in muscle tissue of patients with polymyositis and dermatomyositis treated with corticosteroids显示文摘 | ULFGREN A K GRUNDTMAN C BORG K | 2004 | Arthritis Rheum2004，50，5： | 1 |
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