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| 1 | Radiofrequency ablation for treatment of hypersplenism: A feasible therapeutic option显示文摘We present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. We performed spleen ablation and measured the total spleen and ablated volumes with contrast-enhanced computed tomography and volumetry. No major complications occurred, thrombocytopenia was resolved, and platelet levels remained stable, which allowed for early treatment of the patient's underlying disease. Previous work has shown that splenic radiofrequency ablation is an attractive alternative treatment for hypersplenism induced by liver cirrhosis. We aimed to contribute to the currently sparse literature evaluating the role of radiofrequency ablation(RFA) in the management of hypersplenism. We conclude that splenic RFA appears to be a viable and promising option for the treatment of hypersplenism. | Guilherme Lopes P Martins Joao Paulo G Bernardes Marcello S Rovella Raphael G Andrade Publio Cesar C Viana Paulo Herman Giovanni Guido Cerri Marcos Roberto Menezes | 2015 | World Journal of Gastroenterology2015，21，20： | 17 |
| 2 | Quality of life, physical performance and nutritional status in older patients hospitalized in a cardiology department显示文摘Objectives Quality of life(QoL) is a priority outcome in older adults suffering from cardiovascular diseases. Frailty and poor nutritional status may affect the QoL through mobility disorders and exhaustion. The objective of this study was to determine if physical frailty and nutritional status were associated with QoL, in older cardiology patients. Methods Cross sectional, observational study conducted in a cardiology department from a university hospital. Participants(n = 100) were aged 70 and older. Collected data included age, sex, cardiac diseases, New York Heart Association(NYHA) classification, comorbidities(Charlson Index) and disability. A Short Physical Performance Battery(SPPB), including walking speed assessment was performed;handgrip strength were measured as well as Fried’s frailty phenotype. Nutritional status was assessed using the Mini Nutritional Assessment(MNA) and Body Mass Index(BMI), inflammation by C-reactive protein(CRP). QoL was assessed using the EORTC–QLQ questionnaire. Univariate and multivariate analyses were performed to study the associations between all recorded parameters and QoL. Results In participants(mean age: 79.3 ± 6.7 years;male: 59%), Charlson index, arrhythmia, heart failure, NYHA class III-IV, MNA, disability, walking speed, SPPB score, frailty and CRP were significantly associated with QoL in univariate analysis. Multivariate analysis showed that NYHA class III-IV(P < 0.001), lower MNA score(P = 0.03), frailty(P < 0.0001), and higher CRP(P < 0.001) were independently associated with decreased QoL. Conclusions Frailty, nutritional status and inflammation were independently associated with poor QoL. Further studies are needed to assess the efficacy of nutritional and physical interventions on QoL in this population. | Matthieu Lilamand Mariannick Saintout Marie Vigan Astrid Bichon Laure Tourame Aurélie Brembilla Diet Bernard Iung Dominique Himbert Cédric Laouenan Agathe Raynaud-Simon | 2020 | Journal of Geriatric Cardiology2020，17，7： | 3 |
| 3 | Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘 | Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D | 2013 | MMWR. Morbidity and Mortality Weekly Report2013，，18： | 3 |
| 4 | Community- acquired Staphylococcus aureus pneumonia following influenza and the choice of empirical antibiotic treatment显示文摘 | van Nieuwkoop C Bernards AT Compier EA | 2008 | Ned Tijdschr Geneeskd2008，152，14： | 1 |
| 5 | Surface modification and photosensitisation of TiO2 nanocrystalline films with ascorbic acid 显示文摘 | Xagas A P Bernard M C GofA H | 2000 | J Photochem PhotobiolA : Chem2000，13，2： | 1 |
| 6 | Virulence factors of Helieobaeter pylori显示文摘 | Dundon WG de Bernard M Montecucco C | 2001 | Int J Med Mierobiol2001，290，8： | 1 |
| 7 | A novel plasmidmediated extended-spectrum beta-lactamase not derived from TEM- or SHV-type enzymes显示文摘 | Bernard H Tancrede C Livrelli V | 1992 | J Antimicrob Chemother1992，29，5： | 1 |
| 8 | Cholinergic me-sencephalic neurons are involved in gait and postural disorders in Parkinson disease显示文摘 | Karachi C Grabli D Bernard F A | 2010 | J Clin Invest2010，120，8： | 1 |
| 9 | Silver-modified titanium dioxide thin films for efficient photodegradation of methyl orange 显示文摘 | ARABATZIS I M STERGIOPOULOS T BERNARD M C | 2003 | Appl Catal B: Environ2003，42，： | 1 |
| 10 | Arthritis after infection with Chikungunya virus 显示文摘 | Sanae AOA Bernard C | 2011 | Best Prac Res CL RH2011，25，3： | 1 |
| 11 | Silver- modified titanium dioxide thin films for efficient photo deg- radation of methyl orange 显示文摘 | Arabatzis I M Stergiopoulos T Bernard M C | 2003 | Appl Catal B: Environ2003，42，2： | 1 |
| 12 | Use of surfactant to reduce CO2 mobility in oil displacement 显示文摘 | Bernard G C Holm L W Harvey C P | 1980 | Soc Pet Engrs J1980，20，4： | 1 |
| 13 | Cataclastic Slip Band Distribution in Normal Fault Damage Zones, Nubian Sandstones,Suez Rift显示文摘 | Du Bernard X Labaume P Darcel C | 2002 | Journal of Geophy- sical Research2002，107，： | 1 |
| 14 | Effects of microcystin-LR on development of medaka fish embryos ( Oryzias latipes )显示文摘 | Claire Jacquet Violette Thermes Amaury de Luze Simone Puiseux-Dao Cécile Bernard Jean-Stéphane Joly Franck Bourrat Marc Edery | 2003 | Toxicon2003，，2： | 1 |
| 15 | Purification and characterization of prophenoloxidase from the haemolymph of Locusta migratoria 显示文摘 | Anas C Bernard D Michel B | 1996 | Arch Insect Biochem1996，32，： | 1 |
| 16 | IFN-γ plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis 显示文摘 | Willenborg D O Fordham S Bernard C C | 1996 | J Immunol1996，157，： | 1 |
| 17 | Use of recombinant human DNase for processing of athawed umbilical cord blood transplant in a patient with relapsed acute lymphoblastic leukemia显示文摘 | Beck C Bernard F | 2002 | Ann Hematol2002，81，： | 1 |
| 18 | Taxonomic, phylogenetic, and ecological diversity of methanogenic archaea显示文摘 | Garcia Jean-Louis Bharat K C Patel Bernard Ollivier | 2000 | Anaerobe2000，6，： | 1 |
| 19 | Shape Distribution显示文摘 | Robert O Thomas F Bernard C | 2002 | ACM Transactions on Graphics2002，21，4： | 1 |
| 20 | Specificity of the Human IgE Response to the Different Purified Caseins in Allergy to Cow's Milk Proteins显示文摘 | BERNARD H CREMINON C YVON M | 1998 | International Archives of Allergy and Immunology1998，115，3： | 1 |
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