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| 1 | Treatment of laryngopharyngeal reflux disease: A systematic review显示文摘BACKGROUNG For a long time,laryngopharyngeal reflux disease(LPRD)has been treated by proton pump inhibitors(PPIs)with an uncertain success rate.AIM To shed light the current therapeutic strategies used for LPRD in order to analysis the rationale in the LPRD treatment.METHODS Three authors conducted a PubMed search to identify papers published between January 1990 and February 2019 about the treatment of LPRD.Clinical prospective or retrospective studies had to explore the impact of medical treatment(s)on the clinical presentation of suspected or confirmed LPRD.The criteria for considering studies for the review were based on the population,intervention,comparison,and outcome framework.RESULTS The search identified 1355 relevant papers,of which 76 studies met the inclusion criteria,accounting for 6457 patients.A total of 64 studies consisted of empirical therapeutic trials and 12 were studies where authors formally identified LPRD with pH-monitoring or multichannel intraluminal impedance-pH monitoring(MII-pH).The main therapeutic scheme consisted of once or twice daily PPIs for a duration ranged from 4 to 24 wk.The most used PPIs were omeprazole,esomeprazole,rabeprazole,lansoprazole and pantoprazole with a success rate ranging from 18%to 87%.Other composite treatments have been prescribed including PPIs,alginate,prokinetics,and H2 Receptor antagonists.CONCLUSION Regarding the development of MII-pH and the identification of LPRD subtypes(acid,nonacid,mixed),future studies are needed to improve the LPRD treatment considering all subtypes of reflux. | Jerome R Lechien Francois Mouawad Maria R Barillari Andrea Nacci Seyyedeh Maryam Khoddami Necati Enver Sampath Kumar Raghunandhan Christian Calvo-Henriquez Young-Gyu Eun Sven Saussez | 2019 | World Journal of Clinical Cases2019，7，19： | 9 |
| 2 | Prevalence of hepatitis C virus infection in patients with lymphoprolife relative disorders显示文摘 | Pipan C Barillari G | 1996 | Blood1996，84，： | 1 |
| 3 | Coagulation and oxidative stress plasmatic levels in a type 2 diabetes population显示文摘 | Barillari G Fabbro E Pasca S | 2009 | Blood Coagul Fibrinolysis2009，4，： | 1 |
| 4 | Mental practice is effective in upper limb recocery after stroke a randomized singleblind crossover study显示文摘 | Riccio I Iolascon G Barillari MR | 2010 | Eur J Phys Rehabil Med2010，46，1： | 1 |
| 5 | Coagulation and oxidative stress plasmatic levels in a type 2 diabetes population 显示文摘 | Barillari G Fabbro E Pasca S | 2009 | Blood Coagul Fibrinolysis2009，20，4： | 1 |
| 6 | Surveillance of colorectal caneer:effectiveness of early detection of intraluminal recurrences on prognosis and survival of patients treated for cure显示文摘 | Barillari P Ramacciato G | 1996 | Dis Colon Rectum1996，39，4： | 1 |
| 7 | Prothrombin complex concentrates for urgent antico- agulation reversal in patients with intracranial hemor- rhage显示文摘 | IMBERTI D BARILLARI G BIASIOLI C | 2008 | Pathophysiol Haemost Thromb2008，36，： | 1 |
| 8 | The role eolonoscopy in early diagnosis of intraluminal recurrences in patients already treated for eoloreetal cancer显示文摘 | Barillari P Manetti G | 1996 | Minerva Chit1996，51，11： | 1 |
| 9 | Lung ultrasound:a new tool for the emergency physician显示文摘 | Barillari A Fioretti M | | 0，，： | 1 |
| 10 | HIV protease inhibitors:antiretroviral agents with anti-inflammatory,anti-angiogenic and anti-tumour activity显示文摘 | Monini P Sgadari C Barillari G | | 0，，： | 1 |
| 11 | IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis显示文摘 | Fiorelli VG Barillari E Toschi C | 1999 | Immunology1999，162，： | 1 |
| 12 | Cyanoacrylate glue in the treatment of ano-rectal fistulas 显示文摘 | Barillari P Basso L Larcinese A | 2006 | International Journal of Colorectal Disease2006，21，8： | 1 |
| 13 | In vitro induction of benzo (a) pyrene cell-transforming activity by the glucosinolate gluconasturtiin found in cruciferous vegetables显示文摘 | Perocco P Iori R Barillari J | 2002 | Cancer letters2002，184，1： | 1 |
| 14 | Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats显示文摘 | BARILLARI J LORI R BROCCOLI M | 2007 | Journal of Agricultural and Food Chemistry2007，55，14： | 1 |
| 15 | Occurrence of synchronous colorectal cancer metastasis in the cirrhotic or fatty liver显示文摘 | Iascone C Ruperto M Barillari P | 2005 | Minerva Chir2005，60，3： | 1 |
| 16 | Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of Brassicaceae, differently affect metabolizing enzymes in rats显示文摘 | BARILLARI J LORI R BROCCOLI M | 2007 | Journal of Agricultural and Food Chemistry2007，55，44： | 1 |
| 17 | Isolation of 4- methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (Kaiware Daikon) and its redox properties显示文摘 | BARILLARI J CEVELLATI R PAOLINI M | 2005 | Joumal of Agricultural and Food Chemistry2005，53，： | 1 |
| 18 | IFN-g induces endothe-lial cells to proliferate and to invade the extracellular matrix inresponse to the HIV-1Tat protein:implications for AIDS-Ka-posi's sarcoma pathogenesis显示文摘 | Fiorelli V Barillari G Toschi E | 1999 | J Immunol1999，162，： | 1 |
| 19 | Efficacy and safety of highly purified, doubly virus-inactivated VWF/FVIII concentrates in inherited yon Willebrand' s disease: results of an Italian cohort study on 120 pa- tients characterized by bleeding severity score 显示文摘 | Federici AB Barillari G Zanon E | 2010 | Haemophilia2010，16，1： | 1 |
| 20 | Mental practice is effec- tive in upper limb recovery after stroke:a randomized singleblind cross over study显示文摘 | Riccio I Iolascon G Barillari MR | 2010 | Eur J Phys Rehabil Med2010，46，1： | 1 |
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