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| 1 | Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients显示文摘AIM:To investigate the clinicopathologic characteristics and prognostic implications associated with loss of CDX2 expression in colorectal cancers(CRCs).METHODS:We immunohistochemically evaluated CDX2 expression in 713 CRCs and paired our findings to clinicopathologic and molecular characteristics of each individual.Endpoints included cytokeratin 7 and CK20 expression,microsatellite instability,Cp G island methylator phenotype,and KRAS and BRAF mutation statuses.Univariate and multivariate survival analysis was performed to reveal the prognostic value of CDX2 downregulation.RESULTS:CDX2 expression was lost in 42(5.9%) patients.Moreover,loss of CDX2 expression was associated with proximal location,infiltrative growth,advanced T,N,M and overall stage.On microscopic examination,loss of CDX2 expression was associated with poor differentiation,increased number of tumor-infiltrating lymphocytes,luminal serration and mucin production.Loss of CDX2 expression was also associated with increased CK7 expression,decreased CK20 expression,Cp G island methylator phenotype,microsatellite instability and BRAF mutation.In a univariate survival analysis,patients with loss of CDX2 expression showed worse overall survival(P < 0.001) and progression-free survival(P < 0.001).In a multivariate survival analysis,loss of CDX2 expression was an independent poor prognostic factor of overall survival [hazard ratio(HR) = 1.72,95%CI:1.04-2.85,P = 0.034] and progression-free survival(HR = 1.94,95%CI:1.22-3.07,P = 0.005).CONCLUSION:Loss of CDX2 expression is associated with aggressive clinical behavior and can be used as a prognostic marker in CRCs. | Jeong Mo Bae Tae Hun Lee Nam-Yun Cho Tae-You Kim Gyeong Hoon Kang | 2015 | World Journal of Gastroenterology2015，21，5： | 14 |
| 2 | Stereotactic body radiation therapy for inoperable hepatocellular carcinoma as a local salvage treatment after incomplete transarterial chemoembolization显示文摘 | Jin‐Kyu Kang Mi‐Sook Kim Chul Koo Cho Kwang Mo Yang Hyung Jun Yoo Jin Ho Kim Sun Hyun Bae Da Hoon Jung Kum Bae Kim Dong Han Lee Chul Ju Han Jin Kim Su Cheol Park Young Han Kim | 2012 | Cancer2012，，21： | 3 |
| 3 | Short-term overlap lamivudine treatment with adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B显示文摘AIM:To evaluate the efficacy of short-term overlap lamivudine therapy with adefovir in patients with lamivudine-resistant and nave chronic hepatitis B,we compared patients receiving overlap therapy with those receiving adefovir alone. METHODS:Eighty patients who had received lamivudine treatment for various periods and had a lamivudine- resistant liver function abnormality were enrolled.Forty of these patients received adefovir treatment combined with lamivudine treatment for≥2 mo,while the other 40 received adefovir alone.We assessed the levels of hepatitis B virus(HBV)DNA at 0,12 and 48 wk and serum alanine aminotransferase(ALT)levels after 0,12, 24 and 48 wk of adefovir treatment in each group. RESULTS:We found serum ALT became normalized in 72(87.5%)of the 80 patients,and HBV DNA decreased by≥2 log10 copies/mL in 60(75%)of the 80 patients at the end of a 48-wk treatment.HBV DNA levels were not significantly different between the groups.The improvements in serum ALT were also not significantly different between the two groups. CONCLUSION:These findings suggest short-term overlap lamivudine treatment results in no better virological and biological outcomes than non-overlap adefovir monotherapy. | Soon Woo Nam Si Hyun Bae Seung Woo Lee Yeon Soo Kim Sang Bum Kang Jong Young Choi Se Hyun Cho Seung Kew Yoon Joon-Yeol Han Jin Mo Yang Young Suk Lee | 2008 | World Journal of Gastroenterology2008，14，11： | 3 |
| 4 | Non-invasive assessment of hepatic steatosis: Prospective comparison of the accuracy of imaging examinations显示文摘 | Seung Soo Lee Seong Ho Park Hye Jin Kim So Yeon Kim Min-Yeong Kim Dae Yoon Kim Dong Jin Suh Kang Mo Kim Mi Hyun Bae Joo Yeon Lee Sung-Gyu Lee Eun Sil Yu | 2010 | Journal of Hepatology2010，，4： | 2 |
| 5 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int J Cancer2012，，9： | 2 |
| 6 | Effects of nonylphenoI, bisphenol A, and their mixture on the viviparous swordtail fish ( Xiphophorus helleri) 显示文摘 | Kwak HI Bae MO Lee MH | 2001 | Environ Toxicol Chem2001，20，4： | 1 |
| 7 | Extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue–type of the orbit and ocular adnexa显示文摘 | Jae-Lyun Lee Min-Kyoung Kim Kyung Hee Lee Myung Soo Hyun Hwa Sun Chung Dong Suk Kim Sei One Shin Hee Soon Cho Sung Hwa Bae Hun Mo Ryoo | 2005 | Annals of Hematology2005，，1： | 1 |
| 8 | Tunneling or value addition? Evidence from mergers by Korean business groups 显示文摘 | Kee - Hong Bae Jun - Koo Kang Jin - Mo Kim | 2002 | Journal of Finance2002，57，6： | 1 |
| 9 | Effects of nonylph-enol,bisphenol A,and their mixture on the viviparous swordtail fish (Xiphophorus helleri)显示文摘 | Kwak HI Bae MO Lee MH | 2001 | Environ Toxicol Chem2001，20，4： | 1 |
| 10 | Treatment of ovarian cancer with paclitaxelor carboplatin-based intraperitoneal hyperthermic chemotherapy during secondary surgery 显示文摘 | JEONG HOON BAE JOON MO LEE KI SUNG RYU | 2007 | Gyne-cologic Ontology2007，106，： | 1 |
| 11 | Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-κB显示文摘 | Sun Mi Kim So Yong Lee Jin Suk Cho Seung Mo Son Sang Sook Choi Yeo Pyo Yun Hwan Soo Yoo Do Young Yoon Ki-Wan Oh Sang Bae Han Jin Tae Hong | 2009 | European Journal of Pharmacology2009，，1： | 1 |
| 12 | Anterior urethrectomy for primary carcinoma of the female urethra mimicking a urethral caruncle 显示文摘 | SS JI MO MI JG LEE JH BAE | 2014 | Int Neurourol J2014，17，4： | 1 |
| 13 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int. J. Cancer2012，，9： | 1 |
| 14 | New approaches to pathogenic gene function discovery with human squamous cell cervical carcinoma by gene ontology显示文摘 | Min-Jae Seo Su Mi Bae Yong-Wan Kim Yong Wook Kim Soo Young Hur Duck Young Ro Joon Mo Lee Sung Eun Namkoong Chong Kook Kim Woong Shick Ahn | 2004 | Gynecologic Oncology2004，，3： | 1 |
| 15 | WKYMVm‐Induced Activation of Formyl Peptide Receptor 2 Stimulates Ischemic Neovasculogenesis by Promoting Homing of Endothelial Colony‐Forming Cells显示文摘 | Soon Chul Heo Yang Woo Kwon Il Ho Jang Geun Ok Jeong Jung Won Yoon Chi Dae Kim Sang Mo Kwon Yoe‐Sik Bae Jae Ho Kim | 2014 | Stem Cells2014，，3： | 1 |
| 16 | Comparative study between doxorubicin-eluting beads and conventional transarterial chemoembolization for treatment of hepatocellular carcinoma显示文摘 | Myeong Jun Song Ho Jong Chun Do Seon Song Hee Yeon Kim Sun Hong Yoo Chung-Hwa Park Si Hyun Bae Jong Young Choi U Im Chang Jin Mo Yang Hae Giu Lee Seung Kew Yoon | 2012 | Journal of Hepatology2012，，6： | 1 |
| 17 | Tunneling or Value Addition? Evidence from Mergers by Korean Business Groups 显示文摘 | Kee -Hong Bae Jun J Koo Kang Jin J Mo Kim | 2002 | Journal of Finance2002，57，： | 1 |
| 18 | Usefulness of Multiple Biomarkers for the Prediction of Significant Fibrosis in Chronic Hepatitis B显示文摘 | Seung Ha Park Chang Hoon Kim Dong Joon Kim Ki Tae Suk Jae Youn Cheong Sung Won Cho Seong Gyu Hwang Youn Jae Lee Mong Cho Jin Mo Yang Young Bae Kim | 2011 | Journal of Clinical Gastroenterology2011，，4： | 1 |
| 19 | Multicenter Analysis of Risk Factors for Anastomotic Leakage After Laparoscopic Rectal Cancer Excision: The Korean Laparoscopic Colorectal Surgery Study Group显示文摘 | Jun Seok Park Gyu-Seog Choi Seon Hahn Kim Hyeong Rok Kim Nam Kyu Kim Kang Young Lee Sung Bum Kang Ji Yeon Kim Kil Yeon Lee Byung Chun Kim Byung Noe Bae Gyung Mo Son Sun Il. Lee Hyun Kang | 2013 | Annals of Surgery2013，，4： | 1 |
| 20 | Tunneling or value added? Evidence from mergers by Korean business groups显示文摘 | Bae K Kang Jun - Koo Kim Jin - Mo | 2002 | Journal of Finance2002，67，6： | 1 |
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