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您的检索式：作者名="Asghar Ghasemi"
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| 1 | Nitrate-nitrite-nitrosamines exposure and the risk of type 1 diabetes: A review of current data显示文摘The potential toxic effects of nitrate-nitrite-nitrosamine on pancreatic β cell have remained a controversial issue over the past two decades. In this study, we reviewed epidemiological studies investigated the associations between nitrate-nitrite-nitrosamines exposure, from both diet and drinking water to ascertain whether these compounds may contribute to development of type 1 diabetes. To identify relevant studies, a systematic search strategy of Pub Med, Scopus, and Science Direct was conducted using queries including the key words 'nitrate', 'nitrite', 'nitrosamine' with 'type 1 diabetes' or 'insulin dependent diabetes mellitus'. All searches were limited to studies published in English. Ecologic surveys, case-control and cohort studies have indicated conflicting results in relation to nitrate-nitrite exposure from drinking water and the risk of type 1 diabetes. A null, sometimes even negative association has been mainly reported in regions with a mean nitrate levels < 25 mg/L in drinking water, while increased risk of type 1 diabetes was observed in those with a maximum nitrate levels > 40-80 mg/L. Limited data are available regarding the potential diabetogenic effect of nitrite from drinking water, although there is evidence indicating dietary nitrite could be a risk factor for development of type 1 diabetes, an effect however that seems to be significant in a higher range of acceptable limit for nitrate/nitrite. Current data regarding dietary exposure of nitrosamine and development of type 1 diabetes is also inconsistent. Considering to an increasing trend of type 1 diabetes mellitus(T1DM) along with an elevated nitrate-nitrite exposure, additional research is critical to clarify potential harmful effects of nitrate-nitritenitrosamine exposure on β-cell autoimmunity and the risk of T1DM. | Zahra Bahadoran Asghar Ghasemi Parvin Mirmiran Fereidoun Azizi Farzad Hadaegh | 2016 | World Journal of Diabetes2016，7，18： | 2 |
| 2 | Protein Precipitation Methods Evaluated for Determination of Serum Nitric Oxide End Products by the Griess Assay 显示文摘 | Asghar Ghasemi Mehdi Hedayati Hamed Biabani | 2007 | J Med Sci Res2007，15，2： | 1 |
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