|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Recurrence of inflammatory pseudotumor in the distal bile duct: Lessons learned from a single case and reported cases显示文摘煽动性的 myofibroblastic 肿瘤(IMT ) 或煽动性的假肿瘤(IP ) 广泛地在文学被讨论了。他们通常在肺和上面的呼吸道被发现。然而,包含 biliopancreatic 区域的案例报导在最近的年增加了。限制到胰腺的头或远侧的胆汁管的这些损害的 Immunohistochemical 学习似乎与那些在称为自体免疫的胰腺炎的一个新实体观察了兼容,但是通常强烈的纤维变性反应(带状配列) 支配生产一个团。当这个条件限于胰腺的头时,胆总管可能被煽动性的过程包含,黄疸可以经常发生类似于胰的腺癌。我们以前报导了从与是一个极其稀罕的实体的自体免疫的胰腺炎联系的胆汁管产生的 IMT 的一个案例。在 Kaush-Whipple 切除术以后的四年,平淡的后续上的放射学的检查揭示了一个肿瘤团,建议本地复发。指导超声的 FNA 证实了我们的可疑诊断。作为其它,这个现在的案例建议坚持的后续是必要的以便在这个特定的地点阻止不可逆的肝损坏。 | EM López-Tomassetti Fernández H Díaz Luis A Martín Malagón I Arteaga González A Carrillo Pallarés | 2006 | World Journal of Gastroenterology2006，12，24： | 7 |
| 2 | Targeted cancer therapies显示文摘With unprecedented understanding of molecular events underlying human cancer in this genomic era, a large number of drugs specifically targeting hypothesized oncogenic drivers to which tumors are potentially addicted to have been developed and continue to be developed. These targeted cancer therapies are being actively tested in clinical trials with mixed successes. This editorial provides an overview on successful targeted cancer drugs on the market and those drugs that are in late clinical development stages. Importantly, the article lays out main challenges in developing molecular targeted therapies and potential path forward to overcome these challenges, as well as opportunities for China in this new era of targeted agents. The editorial serves as an introduction to the Targeted Cancer Therapies series that will review in depth of major pathways and drugs targeting these pathways to be published in the coming issues of the Chinese Journal of Cancer. | Li Yan Neal Rosen Carlos Arteaga | 2011 | Chinese Journal of Cancer2011，30，1： | 3 |
| 3 | Strategies for PET imaging of the receptor for advanced glycation endproducts(RAGE)显示文摘The implication of the receptor for advanced glycation end-products(RAGE)in numerous diseases and neurodegenerative disorders makes it interesting both as a therapeutic target and as an inflammatory biomarker.In the context of investigating RAGE as a biomarker,there is interest in developing radiotracers that will enable quantification of RAGE using positron emission tomography(PET)imaging.We have synthesized potential small molecule radiotracers for both the intracellular([18F]InRAGER)and extracellular([18F]RAGER)domains of RAGE.Herein we report preclinical evaluation of both using in vitro(lead panel screens)and in vivo(rodent and nonhuman primate PET imaging)methods.Both radiotracers have high affinity for RAGE and show good brain uptake,but suffer from off-target binding.The source of the off-target PET signal is not attributable to binding to melatonin receptors,but remains unexplained.We have also investigated use of lipopolysaccharide(LPS)-treated mice as a possible animal model with upregulated RAGE for evaluation of new imaging agents.Immunoreactivity of the mouse brain sections revealed increases in RAGE in the male cohorts,but no difference in the female groups.However,it proves challenging to quantify the changes in RAGE due to off-target binding of the radiotracers.Nevertheless,they are appropriate lead scaffolds for future development of 2nd generation RAGE PET radiotracers because of their high affinity for the receptor and good CNS penetration. | Lindsey R.Drake Allen F.Brooks Jenelle Stauff Phillip S.Sherman Janna Arteaga Robert A.Koeppe Aimee Reed Timothy J.Montavon Marc B.Skaddan Peter J.H.Scott | 2020 | Journal of Pharmaceutical Analysis2020，10，5： | 2 |
| 4 | Three-Dimensional Angular Momentum Projected Relativistic Point-Coupling Approach for Low-Lying Excited States in ^24Mg显示文摘在 triaxial 上的完整的三维的尖动量设计相对论的平均数 -- 删除计算第一次被实现。内在的 Lagrangian 是联合模型的一个点,配对关联被单极力量考虑。这个方法被申请在 24Mg 的低激动的状态。对试验性的数据的好同意被作出对有利的裁决扎根的州的性质。在为 2+1 状态的势能表面的最小,与 b?0.55, g?10deg,被用作基础作为与可得到的数据相比调查旋转精力光谱以及相应 B (E2 ) 转变可能性。[从作者抽象] | 尧江明 孟杰 D. Pena Arteaga P. Ring | 2008 | Chinese Physics Letters2008，25，10： | 2 |
| 5 | Inhibition of TGFbeta signaling in cancer therapy显示文摘 | Arteaga CL | 2006 | Curr Opin Genet Dev2006，16，1： | 1 |
| 6 | FAK is required for c-Met/β-catenin-driven hepatocarcinogenesis显示文摘 | Shang N Arteaga M Zaidi A | 2015 | Hepatology2015，61，1： | 1 |
| 7 | Tyrosine kinase inhibitors: why does the current process of clinical development not apply to them? 显示文摘 | Arteaga CL Baselga J | 2004 | Cancer Cell2004，5，： | 1 |
| 8 | Determination of kinetic equations of alkaline activation of blast furnace slag by means of calorimetric data显示文摘 | FERNANDEZ-JIMENEZ A PUERTAS F ARTEAGA A | 1998 | J Therm Anal Calori1998，52，2： | 1 |
| 9 | ErbB - targeted therapeuticapproaches in human cancer显示文摘 | ARTEAGA C L | 2003 | Exp Cell Res2003，284，1： | 1 |
| 10 | Deteetion and identification of species of the genus Fabavirus by RT- PCR with a single pair of primers显示文摘 | Ferrer R M Luis Arteaga M Guerri J | 2007 | Journal Of VirologicalMethods2007，144，： | 1 |
| 11 | The PI3K/AKT pathway as a target for cancer treatment显示文摘 | Mayer IA Arteaga CL | 2016 | Annu Rev Med2016，67，3： | 1 |
| 12 | The epidermal growth factor receptor:from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia 显示文摘 | Arteaga CL | 2001 | J Clin Oncol2001，19，18： | 1 |
| 13 | Inhibitors of HER2/neu(erbB-2) signal transduction显示文摘 | Arteaga CL Chinratanalab W Carter MB | 2001 | Semin Oncol2001，28，618： | 1 |
| 14 | Cdk Inhibitor p27kipl and hormone dependence in breast cancer 显示文摘 | Arteaga CL | 2004 | Clin Cancer Res2004，10，12： | 1 |
| 15 | The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia 显示文摘 | ARTEAGA M F MIKESCH J H QIU J | 2013 | Cancer Cell2013，23，3： | 1 |
| 16 | PC-SPES inhibits colon cancer growth in vitro and in vivo显示文摘 | Huerta S Arteaga JR Irwin RW | 2002 | Cancer Res2002，62，： | 1 |
| 17 | Apoptosis of cultured granulose - lutein cells is reduced by insu- lin -like growth factor 1 and may correlate with embryo fragmentation and pregnancy rate 显示文摘 | Bencomo E Perez R Arteaga MF | 2006 | Fertil Steril2006，85，2： | 1 |
| 18 | Epidermal growth factor receptor dependence in human tumors:more than just expression?显示文摘 | Arteaga CL | 2002 | Oncologist2002，7，4： | 1 |
| 19 | Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia显示文摘 | Arteaga C L | 2002 | Semin Oncol2002，29，514： | 1 |
| 20 | Epidermal growth factor receptor dependence in human tumors:more than just expression显示文摘 | ARTEAGA C L | 2002 | Oncologist2002，7，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员