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231篇 您的检索式:作者名="Arnold M B"
    题名 作者 年代 出处 被引量
1急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI.Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS 2017中华神经外科疾病研究杂志2017,16,6:8
2DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection显示文摘Oertli Mathias Sundquist Malin Hitzler Iris Engler Daniela B Arnold Isabelle C Reuter Sebastian Maxeiner Joachim Hansson Malin Taube Christian Quiding-J?rbrink Marianne Müller Anne 2012EN2012,,3:5
3Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies.Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter 2015World Journal of Psychiatry2015,5,4:3
4Rotational relaxation measurements of laser excited Hydrogen fluoride显示文摘Peterson L M Lindgulst G H Arnold C B 1974J Chem Phys1974,61,8:2
5Myostatin knockout in mice increases myogenesis and decreases adipogenesis 显示文摘Lin J Arnold H B Della- fera M A 2002Biochem Biophys Res Commun2002,291,3:1
6Gaining Competitive Advantage through Environmental Investments显示文摘Bonifant B C Arnold M B Long F J 1995Business Horizons1995,38,4:1
7Molecular effects of theherbal compound C-SPES: identification of activity pathways in prostate carcinoma 显示文摘Bonham M Arnold H Montgomery B 2002Cancer Res2002,62,14:1
8Gas permeation properties of poly (1,1'-dihydroperfluorooctyl acrylate ), poly ( 1,1'- dihydroperfluorooctyl methacrylate ), and poly (styrene)-b-poly (1,1'-dihydroperfluorooctyl acrylate) block copolymers显示文摘ARNOLD M E NAGAI K FREEMAN B D 2001Macromolecules2001,34,16:1
9The impact of glycosylation on the biological function and structure of human im- munoglobulins显示文摘ARNOLD J N WORMALD M R SMI R B 2007Annu Rev Immunol2007,25,:1
10Local elastic proper ties of a metallic glass 显示文摘Wagner H Bedorf D Kuchemann S Schwabe M Zhang B Arnold W Samwer K 2011Nature Materials2011,10,6:1
11The impact of glycosylation on the biological function and structure of human immunoglobulin's显示文摘Arnold J N Wormald M R Sim R B 2007Ann Rev Immunol2007,25,:1
12The measurement of responsibility in Children显示文摘Dale B Harris Kenneth E Clark Arnold M Rose Frances Valasek 1954Child Development1954,25,1:1
13A novel dynamin Ⅲisoform is up-regulated in the central nervous system in hypothyroidism显示文摘Arnold A M Anderson G W McIver B 2003Int J Deve Neuroscience2003,21,:1
14Adoptive transfer of an auto-immunological labyrinthitis in the guinea pig:Animal model for a sympathetic cochleolabyrinthitis 显示文摘Gloddek B Rogowski M Arnold W 1994Clin Exp Immunol1994,97,:1
15DAE time integration for real-time applications in multibody dynamics 显示文摘Burgermeister B Arnold M Esterl B 2006Zeitschrift Angewandte Mathematik Mechanik2006,86,10:1
16Synergistic activa- tion of estrogen receptor with combinations of environmental chemicals(estrogen mimicking pollutants linked to human disea ses)显示文摘Arnold S F Klotz D M Collins B M 1996Science1996,272,:1
17Conflicts regarding decisions to limit treatment: A different diagnosis 显示文摘Goold S D Williams B Arnold R M 2000JAMA2000,283,7:1
18Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase 显示文摘Kadenbach B Hiittemann M Arnold S 2000Free Radical Biology and Medi-cine2000,29,:1
19Myosta-tin knockout in mice increases myogenesis and de-creases adipogenesis显示文摘Lin J Arnold H B Della-Fera M A 2002Biochem Biophys Res Com-mun2002,291,3:1
20Minocycline neuroprotects, reduces microgliosis and inhibits caspase protease expression early after spinal cord injury显示文摘Festoff B W Ameenuddin S Arnold P M 2006J Neurochem2006,97,5:1
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